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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 20,876–20,900 of 27,380 studies, newest first · page 836 of 1096.

April 2010 17

  1. 2010-04-01

    End of life care for community dwelling older people with dementia: an integrated review

    ✓ Peer-reviewed End-of-life care International journal of geriatric psychiatry

    Key finding: Research on end-of-life care for people with dementia has yet to develop interventions that address the particular challenges that dying with dementia poses. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2010-04-01

    The older adult driver with cognitive impairment: "It's a very frustrating life"

    ✓ Peer-reviewed Clinical safety JAMA

    Key finding: Yet clinicians are called on by patients, their families, other health professionals, and often their state's Department of Motor Vehicles to assess their patients' fitness to drive and to make recommendations about driving privileges. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2010-04-01

    Cognitive intervention programs for individuals with mild cognitive impairment: systematic review of the literature

    ✓ Peer-reviewed Prevention trials The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    Key finding: The data showed statistically significant improvements at the end of training on 44% of objective measures of memory, when compared with 12% of objective measures of cognition other than memory. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2010-04-01

    Place of Death of Older Persons with Dementia. A Study in Five European Countries

    ✓ Peer-reviewed Health systems and care delivery Journal of the American Geriatrics Society

    Key finding: Multivariate analysis showed that place of death was related to age, sex, available hospital and nursing home beds, and country of residence. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2010-04-01

    Olfactory epithelium amyloid-beta and paired helical filament-tau pathology in Alzheimer disease

    ✓ Peer-reviewed Brain tissue and pathology Annals of neurology

    Key finding: Olfactory dysfunction is common in Alzheimer disease (AD) and other neurodegenerative diseases. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2010-04-01

    Alzheimer's disease phenotypes and genotypes associated with mutations in presenilin 2

    ✓ Peer-reviewed Brain tissue and pathology Brain : a journal of neurology

    Key finding: Eighteen presenilin 2 mutations have been reported, although not all have been confirmed pathogenic. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2010-04-01

    Brain-derived neurotrophic factor is associated with age-related decline in hippocampal volume

    ✓ Peer-reviewed Brain tissue and pathology The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: In rodents, brain-derived neurotrophic factor (BDNF) promotes the growth and proliferation of cells in the hippocampus and is important in long-term potentiation and memory formation. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2010-04-01

    Hippocampal, caudate, and ventricular changes in Parkinson's disease with and without dementia

    ✓ Peer-reviewed Cognitive tests and assessment Movement disorders : official journal of the Movement Disorder Society

    Key finding: Using radial distance mapping, we studied the 3D structural and volumetric differences between the hippocampi, caudates, and lateral ventricles in 20 cognitively normal elderly (NC), 12 cognitively normal PD (PDND), 8 PDMCI, and 15 PDD subjects and examined the associations between these structures and Unified Parkinson's Disease Rating Scale (UPDRS) Part III:motor subscale and Mini-Mental State Examination (MMSE) performance. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2010-04-01

    NIH state-of-the-science conference statement: Preventing Alzheimer's disease and cognitive decline

    ✓ Peer-reviewed Mild cognitive impairment NIH consensus and state-of-the-science statements

    Key finding: Evidence is insufficient to support the use of pharmaceutical agents or dietary supplements to prevent cognitive decline or Alzheimer’s disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2010-04-01

    What is semantic dementia?: a cohort study of diagnostic features and clinical boundaries

    ✓ Peer-reviewed Digital health tools Archives of neurology

    Key finding: Semantic dementia is distinguishable from other presentations of frontotemporal dementia and Alzheimer disease, not only by fluent speech and impaired comprehension without loss of episodic memory, syntax, and phonology but also by empty, garrulous speech with thematic perseverations, semantic paraphasias, and poor category fluency. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2010-04-01

    Blueberry supplementation improves memory in older adults

    ✓ Peer-reviewed How common it is Journal of agricultural and food chemistry

    Key finding: In addition, anthocyanins have been associated with increased neuronal signaling in brain centers, mediating memory function as well as improved glucose disposal, benefits that would be expected to mitigate neurodegeneration. +2 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2010-04-01

    Prediction of dementia by subjective memory impairment: effects of severity and temporal association with cognitive impairment

    ✓ Peer-reviewed How common it is Archives of general psychiatry

    Key finding: The prediction of dementia in AD by SMI with subsequent amnestic MCI supports the model of a consecutive 3-stage clinical manifestation of AD from SMI via MCI to dementia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2010-04-01

    When, where, and how the corpus callosum changes in MCI and AD: a multimodal MRI study

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: Callosal changes are already present in patients with amnestic mild cognitive impairment (MCI) and mild Alzheimer disease (AD). +2 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2010-04-01

    Reduced lean mass in early Alzheimer disease and its association with brain atrophy

    ✓ Peer-reviewed Brain scans and imaging Archives of neurology

    Key finding: Lean mass was reduced in persons with early AD compared with controls without dementia (F = 7.73; P = .006) after controlling for sex. +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2010-04-01

    "I know what you told me, but this is what I think:" perceived risk of Alzheimer disease among individuals who accurately recall their genetics-based risk estimate

    ✓ Peer-reviewed Treatments Genetics in medicine : official journal of the American College of Medical Genetics

    Key finding: Among the 158 participants who accurately recalled their Alzheimer disease risk assessment 6 weeks after risk disclosure, 75 (47.5%) believed their Alzheimer disease risk was more than 5% points different from the Alzheimer disease risk estimate they were given. +1 more finding

    Full summary, score breakdown and related studies → Original source

  16. 2010-04-01

    A single ascending dose study of bapineuzumab in patients with Alzheimer disease

    ✓ Peer-reviewed Treatments Alzheimer disease and associated disorders

    Key finding: PK analysis demonstrated a half-life of 21 to 26 days, supporting a 13-week dosing interval for bapineuzumab. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2010-04-01

    Inflammation, cytokines, immune response, apolipoprotein E, cholesterol, and oxidative stress in Alzheimer disease: therapeutic implications

    ✓ Peer-reviewed Genetics Rejuvenation research

    Key finding: Understanding the pathophysiology process of AD plays a prominent role in new strategies for extending the health of the elderly population. +4 more findings

    Full summary, score breakdown and related studies → Original source

March 2010 8

  1. 2010-03-31

    Val(8)GLP-1 rescues synaptic plasticity and reduces dense core plaques in APP/PS1 mice

    ✓ Peer-reviewed Drug development Neurobiology of aging

    Key finding: LTP was also enhanced in 18-month-old wild type mice, indicating that Val(8)GLP-1 also ameliorates age-related synaptic degenerative processes. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2010-03-31

    Beneficial effect of human anti-amyloid-beta active immunization on neurite morphology and tau pathology

    ✓ Peer-reviewed Treatments Brain : a journal of neurology

    Key finding: Hippocampal sections from five patients with Alzheimer's disease enrolled in the AN1792 Phase 2a trial were compared with those from 13 non-immunized Braak-stage and age-matched patients with Alzheimer's disease, and eight age-matched non-demented controls. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2010-03-31

    Caspase activation precedes and leads to tangles

    ✓ Peer-reviewed Lewy body dementia Nature

    Key finding: Studies of post-mortem tissue have shown that the location of fibrillar tau deposits, called neurofibrillary tangles (NFT), matches closely with regions of massive neuronal death, severe cytological abnormalities, and markers of caspase activation and apoptosis, leading to the idea that tangles cause neurodegeneration in Alzheimer's disease and tau-related frontotemporal dementia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2010-03-30

    Selective neuronal vulnerability to oxidative stress in the brain

    ✓ Peer-reviewed Disease mechanisms Frontiers in aging neuroscience

    Key finding: Because of their selective vulnerability, these neurons are usually the first to exhibit functional decline and cell death during normal aging, or in age-associated neurodegenerative diseases, such as Alzheimer's disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2010-03-29

    A novel Abeta isoform pattern in CSF reflects gamma-secretase inhibition in Alzheimer disease

    ✓ Peer-reviewed Treatments Alzheimer's research & therapy

    Key finding: CSF Abeta1-14, Abeta1-15, and Abeta1-16 increase during gamma-secretase inhibitor treatment in AD, even at doses that do not affect Abeta1-42 or Abeta1-40, probably because of increased substrate availability of the C99 APP stub (APP beta-CTF) induced by gamma-secretase inhibition. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2010-03-27

    Altered glial-neuronal crosstalk: cornerstone in the pathogenesis of hepatic encephalopathy

    ✓ Peer-reviewed Biomarkers Neurochemistry international

    Key finding: Decreased expression of EAAT-2 results in decreased glutamate transport and impaired cycling of glutamate-glutamine between astrocytes and neurons, as well as increased extracellular glutamate, activation of the NMDA receptor-mediated cGMP-NO signal transduction pathway, and nitration of tyrosine residues on key astroglial proteins such as glutamine synthetase (GS) and the MBR. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2010-03-25

    High-molecular-weight beta-amyloid oligomers are elevated in cerebrospinal fluid of Alzheimer patients

    ✓ Peer-reviewed Mild cognitive impairment FASEB journal : official publication of the Federation of American Societies for Experimental Biology

    Key finding: Analysis of Abeta oligomers derived from synthetic Abeta 1-42, by size-exclusion chromatography (SEC), revealed that our ELISA specifically detected HMW Abeta oligomers of 40-200 kDa. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2010-03-25

    Predicting clinical scores from magnetic resonance scans in Alzheimer's disease

    ✓ Peer-reviewed Digital health tools NeuroImage

    Key finding: Training with one data set and testing with another demonstrated stability between data sets. +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →