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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 21,126–21,150 of 27,380 studies, newest first · page 846 of 1096.

December 2009 25

  1. 2009-12-15

    Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

    ✓ Peer-reviewed Biomarkers The Lancet Neurology

    This study proposes a model that relates disease stages to Alzheimer's disease biomarkers.

    Full summary, score breakdown and related studies → Original source

  2. 2009-12-13

    Microglia: biology and pathology

    ✓ Peer-reviewed Inflammation and the immune system Acta neuropathologica

    Key finding: More than 10,000 articles have been published during this time. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2009-12-13

    Okadaic acid induces apoptosis in Down syndrome fibroblasts

    ✓ Peer-reviewed Down syndrome and Alzheimer's Toxicology in vitro : an international journal published in association with BIBRA

    Key finding: Down's syndrome (DS) is characterized by several pathological aspects leading to an increased susceptibility to cardiovascular diseases, infections, leukemia, endocrine alterations.

    Full summary, score breakdown and related studies → Original source

  4. 2009-12-11

    Long-term inhibition of dipeptidyl peptidase-4 in Alzheimer's prone mice

    ✓ Peer-reviewed Drug development Experimental gerontology

    Key finding: The treatments counteracted: (i) the memory impairment in the contextual fear conditioning test; (ii) increased the brain levels of GLP-1; (iii) produced significant reductions of nitrosative stress and inflammation hallmarks within the brain, as well as (iv) a significant diminution in the ultimate number and total area of betaAPP and Abeta deposits. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2009-12-11

    The role of event-related potentials in cognitive decline in Alzheimer's disease

    ✓ Peer-reviewed Mild cognitive impairment Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology

    Key finding: The combination of neuropsychological tests and P300 measurements proved useful in improving reliability and increasing sensitivity to early cognitive decline or disease progression in AD patients. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2009-12-11

    Atrial fibrillation is independently associated with senile, vascular, and Alzheimer's dementia

    ✓ Peer-reviewed Getting a diagnosis Heart rhythm

    Key finding: Patients with dementia were older and had higher rates of hypertension, coronary artery disease, renal failure, heart failure, and prior strokes. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2009-12-09

    Association of parental dementia with cognitive and brain MRI measures in middle-aged adults

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: Studies of autosomal dominant Alzheimer disease (AD) have shown structural and cognitive changes in mutation carriers decades prior to clinical disease.

    Full summary, score breakdown and related studies → Original source

  8. 2009-12-04

    Targeting p38 MAPK pathway for the treatment of Alzheimer's disease

    ✓ Peer-reviewed Inflammation and the immune system Neuropharmacology

    Key finding: The p38 MAPK signalling has been widely accepted as a cascade contributing to neuroinflammation. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2009-12-03

    Predicting six-month mortality for patients who are on maintenance hemodialysis

    ✓ Peer-reviewed End-of-life care Clinical journal of the American Society of Nephrology : CJASN

    Key finding: An integrated 6-mo prognostic tool was developed and validated for the HD population.

    Full summary, score breakdown and related studies → Original source

  10. 2009-12-03

    FUS mutations in amyotrophic lateral sclerosis: clinical, pathological, neurophysiological and genetic analysis

    ✓ Peer-reviewed Brain tissue and pathology Journal of neurology, neurosurgery, and psychiatry

    Key finding: FUS gene mutations were recently identified in familial amyotrophic lateral sclerosis (ALS). +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2009-12-03

    Two-year outcome of MCI subtypes and aetiologies in the Göteborg MCI study

    ✓ Peer-reviewed Tau biomarkers Journal of neurology, neurosurgery, and psychiatry

    Key finding: After 2 years, 34 subjects (16%) were lost for follow-up. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2009-12-03

    Gain and loss of function of ALS-related mutations of TARDBP (TDP-43) cause motor deficits in vivo

    ✓ Peer-reviewed Lewy body dementia Human molecular genetics

    Key finding: Together these approaches showed that TARDBP mutations cause motor neuron defects and toxicity, suggesting that both a toxic gain of function as well as a novel loss of function may be involved in the molecular mechanism by which mutant TDP-43 contributes to disease pathogenesis.

    Full summary, score breakdown and related studies → Original source

  13. 2009-12-02

    ApoE4 decreases spine density and dendritic complexity in cortical neurons in vivo

    ✓ Peer-reviewed Genetics The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Using Golgi staining, we found age-dependent effects of APOE4 on spine density in the cortex. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2009-12-02

    Automated detection of brain atrophy patterns based on MRI for the prediction of Alzheimer's disease

    ✓ Peer-reviewed Mild cognitive impairment NeuroImage

    Key finding: Subjects with mild cognitive impairment (MCI) have an increased risk to develop Alzheimer's disease (AD). +2 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2009-12-01

    Effect of quinolinic acid on human astrocytes morphology and functions: implications in Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Journal of Neuroinflammation

    Key finding: We assessed the stimulatory effects of QUIN at low physiological to high excitotoxic concentrations in comparison with the cytokines commonly associated with AD including IFN-gamma and TNF-alpha on primary human astrocytes. +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2009-12-01

    Amyloid Deposition and Inflammation in APPswe/PS1dE9 Mouse Model of Alzheimers Disease

    ✓ Peer-reviewed Biomarkers Current Alzheimer Research

    Key finding: Alzheimer's disease (AD) is characterized by amyloid plaques and neurofibrillary tangles associated with chronic inflammation. +2 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2009-12 month only

    Cerebrospinal fluid beta-amyloid and dynabridging in Alzheimer's disease drug development

    ✓ Peer-reviewed Tau biomarkers Biomarkers in medicine

    Key finding: Studies have revealed the diagnostic potential of CSF amyloid-beta, tau and phosphorylated tau levels.

    Full summary, score breakdown and related studies → Original source

  18. 2009-12-01

    Amyloid-beta as a positive endogenous regulator of release probability at hippocampal synapses

    ✓ Peer-reviewed Disease mechanisms Nature neuroscience

    Key finding: These observations suggest that endogenous Abeta peptides have a crucial role in activity-dependent regulation of synaptic vesicle release and might point to the primary pathological events that lead to compensatory synapse loss in Alzheimer's disease.

    Full summary, score breakdown and related studies → Original source

  19. 2009-12-01

    Cholesterol metabolism and transport in the pathogenesis of Alzheimer's disease

    ✓ Peer-reviewed Drug development Journal of neurochemistry

    Key finding: Taken together, these findings provide strong evidence that changes in cholesterol metabolism are intimately involved in AD pathogenic processes.

    Full summary, score breakdown and related studies → Original source

  20. 2009-12-01

    Neuropathology of non-motor features of Parkinson disease

    ✓ Peer-reviewed Brain scans and imaging Parkinsonism & related disorders

    Key finding: Extrapyramidal signs in PD are tightly linked to striatonigral dopaminergic denervation associated with neuronal loss and Lewy bodies in the residual neurons of the substantia nigra.

    Full summary, score breakdown and related studies → Original source

  21. 2009-12-01

    One-year brain atrophy evident in healthy aging

    ✓ Peer-reviewed Brain scans and imaging The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: In the present study, 142 healthy elderly participants (60-91 years of age) were followed with repeated MRI, and were compared with 122 patients with mild to moderate Alzheimer's disease (AD). +2 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2009-12-01

    Anterior temporal involvement in semantic word retrieval: voxel-based lesion-symptom mapping evidence from aphasia

    ✓ Peer-reviewed Vascular contributions Brain : a journal of neurology

    Key finding: In picture naming, semantic errors (horse for goat) generally result from something having gone awry in lexical access such that the right concept was mapped to the wrong word. +2 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2009-12-01

    Cognitive decline and brain volume loss as signatures of cerebral amyloid-beta peptide deposition identified with Pittsburgh compound B: cognitive decline associated with Abeta deposition

    ✓ Peer-reviewed Hippocampus size on brain scans Archives of neurology

    Key finding: The in vivo measure of cerebral amyloidosis known as [(11)C]PiB is associated with cross-sectional regionally specific brain atrophy and longitudinal cognitive decline in multiple cognitive domains that occur before the clinical diagnosis of Alzheimer disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2009-12-01

    Mild cognitive impairment: ten years later

    ✓ Peer-reviewed Mild cognitive impairment Archives of Neurology

    In the past 10 years, there has been a virtual explosion in the literature concerning the construct of mild cognitive impairment.

    Full summary, score breakdown and related studies → Original source

  25. 2009-12-01

    High striatal amyloid beta-peptide deposition across different autosomal Alzheimer disease mutation types

    ✓ Peer-reviewed Risk genes beyond APOE Archives of neurology

    Key finding: Mutations in the amyloid precursor protein (APP), presenilin 1 (PSEN1), and presenilin 2 (PSEN2) genes lead to increased Abeta levels before symptoms arise. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →