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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 14,751–14,775 of 27,380 studies, newest first · page 591 of 1096.

September 2017 25

  1. 2017-09-12

    Plasma amyloid β 42/40 ratios as biomarkers for amyloid β cerebral deposition in cognitively normal individuals

    ✓ Peer-reviewed Biomarkers Alzheimer's & dementia (Amsterdam, Netherlands)

    Key finding: These findings support the use of plasma Aβ42/40 ratios as surrogate biomarkers of cortical Aβ deposition and enrichment tools, reducing the number of subjects submitted to invasive tests and, consequently, recruitment costs in clinical trials targeting cognitively normal individuals. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2017-09-12

    Alzheimer's disease prevention: from risk factors to early intervention

    ✓ Peer-reviewed Prevention and risk Alzheimer's research & therapy

    Key finding: Disappointing results from clinical trials performed in mild-moderate AD dementia combined with clear epidemiological evidence on AD risk factors are contributing to the development of primary prevention initiatives. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2017-09-11

    Rates of hippocampal atrophy and presence of post-mortem TDP-43 in patients with Alzheimer's disease: a longitudinal retrospective study

    ✓ Peer-reviewed Hippocampus size on brain scans The Lancet. Neurology

    Key finding: We aimed to investigate whether hippocampal TDP-43 is associated with increased rates of hippocampal atrophy. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2017-09-11

    TREM2 promotes Aβ phagocytosis by upregulating C/EBPα-dependent CD36 expression in microglia

    ✓ Peer-reviewed TREM2 and immune genetics Scientific reports

    Key finding: We found that learning and memory functions were improved in aged TREM2 TG mice, with the opposite effects in KO mice. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2017-09-11

    The relationship between obesity and cognitive health and decline

    ✓ Peer-reviewed Prevention and risk The Proceedings of the Nutrition Society

    Key finding: Anthropometric measures of obesity are also associated with reduced neural integrity (e.g. grey and white matter atrophy). +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2017-09-08

    Optical coherence tomography identifies outer retina thinning in frontotemporal degeneration

    ✓ Peer-reviewed Tau biomarkers Neurology

    Key finding: Using a cross-sectional design, we examined retinal structure in 38 consecutively enrolled patients with FTD and 44 controls using a standard SD-OCT protocol. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2017-09-07

    Motor function deficits in the 12 month-old female 5xFAD mouse model of Alzheimer's disease

    ✓ Peer-reviewed Risk factors Behavioural brain research

    Key finding: The 5xFAD mice did not show deficits in the ability of peripheral motor nerves to drive muscle output, suggesting that motor impairments are not due to dysfunction in peripheral motor nerves. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2017-09-07

    Anti-inflammatory effects of flavonoids in neurodegenerative disorders

    ✓ Peer-reviewed Inflammation and the immune system European journal of medicinal chemistry

    Key finding: The activation of microglia is the main feature of neuroinflammation, promoting the release of pro-inflammatory cytokines and resulting in the progressive neuronal cell death. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2017-09-07

    Prevalence of mild behavioral impairment in mild cognitive impairment and subjective cognitive decline, and its association with caregiver burden

    ✓ Peer-reviewed Caregiving International psychogeriatrics

    Key finding: Prevalence estimates across MBI domains were affective dysregulation (77.8%); impulse control (64.4%); decreased motivation (51.7%); social inappropriateness (27.8%); and abnormal perception or thought content (8.7%). +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2017-09-07

    Defining Optimal Brain Health in Adults: A Presidential Advisory From the American Heart Association/American Stroke Association

    ✓ Peer-reviewed Prevention and risk Stroke

    Key finding: Advances in our understanding of the role of cardiovascular risks have shown them to be closely associated with cognitive impairment and dementia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2017-09-06

    Dementia risk and prevention by targeting modifiable vascular risk factors

    ✓ Peer-reviewed Prevention trials Journal of neurochemistry

    Key finding: Secondary prevention trials need to be redesigned based on the risk profile of individual subjects, which require the use of validated and standardized clinical, biological, and neuroimaging biomarkers. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2017-09-06

    MicroRNA Profiling in Aging Brain of PSEN1/PSEN2 Double Knockout Mice

    ✓ Peer-reviewed Risk genes beyond APOE Molecular neurobiology

    Key finding: To investigate the effect of aging on the changes in microRNA expressions in the Alzheimer's disease animal model, we selected 37 hippocampal microRNAs whose expression in 12- and 18-month aged mice changed significantly using microRNA microarray. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2017-09-05

    Hospitalizations for ambulatory care sensitive conditions and unplanned readmissions among Medicare beneficiaries with Alzheimer's disease

    ✓ Peer-reviewed Digital health tools Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Our findings may suggest potential deficiencies in ambulatory care and postdischarge care related to managing comorbidities among Medicare fee-for-service ADRD patients. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2017-09-05

    Antibiotic-induced perturbations in microbial diversity during post-natal development alters amyloid pathology in an aged APP SWE /PS1 ΔE9 murine model of Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms Scientific reports

    Key finding: We show that early post-natal (P) ABX treatment (P14-P21) results in long-term alterations of gut microbial genera (predominantly Lachnospiraceae and S24-7) and reduction in brain Aβ deposition in aged APP SWE /PS1 ΔE9 mice. +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2017-09-04

    Microbiome-Derived Lipopolysaccharide Enriched in the Perinuclear Region of Alzheimer’s Disease Brain

    ✓ Peer-reviewed Disease mechanisms Frontiers in Immunology

    Key finding: Abundant clinical, epidemiological, imaging, genetic, molecular and pathophysiological data together indicate that there occur an unusual inflammatory reaction and a disruption of the innate-immune signaling system in Alzheimer’s disease (AD) brain.

    Full summary, score breakdown and related studies → Original source

  16. 2017-09-04

    Quantification of plasma phosphorylated tau to use as a biomarker for brain Alzheimer pathology: pilot case-control studies including patients with Alzheimer's disease and down syndrome

    ✓ Peer-reviewed Biomarkers Molecular neurodegeneration

    Key finding: We report for the first time quantitative data on the plasma levels of p-tau181 in controls and patients with AD and DS, and these data suggest that the plasma p-tau181 is a promising blood biomarker for brain AD pathology. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2017-09-01

    Neuropsychiatric symptoms in Alzheimer's disease: associations with caregiver burden and treatment outcomes

    ✓ Peer-reviewed Caregiving QJM : monthly journal of the Association of Physicians

    Key finding: The mean follow-up interval was 25.0 ± 12.2 months, and two patients died during follow-up. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2017-09 month only

    Pharmacotherapy for Vascular Cognitive Impairment

    ✓ Peer-reviewed Treatments CNS drugs

    Key finding: Donepezil has shown some cognitive benefit in patients with VaD only, and galantamine has shown some benefit in mixed dementia (AD/VaD). +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2017-09-01

    AChE Inhibitors and NMDA Receptor Antagonists in Advanced Alzheimer's Disease

    ✓ Peer-reviewed Treatments The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists

    Key finding: The evidence to support a specific time frame for discontinuation of Alzheimer's disease treatment is limited. +1 more finding

    Full summary, score breakdown and related studies → Original source

  20. 2017-09-01

    Repeat Hospitalizations Predict Mortality in Patients With Heart Failure

    ✓ Peer-reviewed Digital health tools Military medicine

    Key finding: Repeat HF hospitalizations remain a strong predictor of mortality for existing patients with HF. +2 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2017-09-01

    Microglia emerge as central players in brain disease

    ✓ Peer-reviewed Inflammation and the immune system Nature medicine

    Key finding: There has been an explosion of new findings recently giving us insights into the involvement of microglia in central nervous system (CNS) disorders. +4 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2017-09-01

    Hearing Impairment, Mild Cognitive Impairment, and Dementia: A Meta-Analysis of Cohort Studies

    ✓ Peer-reviewed Risk factors Dementia and geriatric cognitive disorders extra

    Key finding: The meta-analysis showed that hearing impairment is associated with a higher risk of mild cognitive impairment and dementia among older adults. +3 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2017-09-01

    A New Treatment Strategy for Parkinson's Disease through the Gut-Brain Axis: The Glucagon-Like Peptide-1 Receptor Pathway

    ✓ Peer-reviewed Drug development Cell transplantation

    Key finding: Common pathophysiological features exist between T2DM, AD, and PD, including oxidative stress, inflammation, insulin resistance, abnormal protein processing, and cognitive decline, and suggest that effective drugs for T2DM that positively impact the gut-brain axis could provide an effective treatment option for neurodegenerative diseases.

    Full summary, score breakdown and related studies → Original source

  24. 2017-09-01

    Distinct 18F-AV-1451 tau PET retention patterns in early- and late-onset Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging Brain : a journal of neurology

    Key finding: Individuals with late-onset Alzheimer's disease (>65 years) typically present with medial temporal lobe neurodegeneration and predominantly amnestic symptomatology, while patients with early-onset Alzheimer's disease (<65 years) exhibit greater neocortical involvement associated with a clinical presentation including dyspraxia, executive dysfunction, or visuospatial impairment. +2 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2017-09-01

    18 F-AV-1451 and CSF T-tau and P-tau as biomarkers in Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging EMBO molecular medicine

    Key finding: CSF T-tau and P-tau were highly correlated ( R = 0.92, P < 0.001), but they were only moderately associated with retention of 18 F-AV-1451, and mainly in demented AD patients. 18 F-AV-1451, but not CSF T-tau or P-tau, was strongly associated with atrophy and cognitive impairment. +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →