Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 27,251–27,275 of 27,380 studies, newest first · page 1091 of 1096.
March 1986 2
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1986-03-01
Hearing impairment and cognitive decline in senile dementia of the Alzheimer's type
59/100 ✓ Peer-reviewed Risk factors Journal of the American Geriatrics Society
Key finding: Decline in cognitive function one year later, however, was nearly twice as great in the impaired hearing group, a statistically significant difference (P less than .05, by one-tailed t test) even when controlled for age and initial cognitive function. +1 more finding
Full summary, score breakdown and related studies → Original source
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1986-03-01
Determination in human cerebrospinal fluid of glial fibrillary acidic protein, S-100 and myelin basic protein as indices of non-specific or specific central nervous tissue pathology
33/100 ✓ Peer-reviewed Biomarkers Clinica chimica acta; international journal of clinical chemistry
Key finding: Isolated increases of GFAp could be demonstrated in patients with dementia (Alzheimer type or multi-infarct dementia) or syringomyelia. +1 more finding
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February 1986 1
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1986-02-01
Bedside cognitive screening instruments. A critical assessment
36/100 ✓ Peer-reviewed Clinical safety The Journal of nervous and mental disease
Key finding: However, there is currently no evidence that the tests increase the level of diagnostic accuracy achieved through clinical examination alone. +4 more findings
Full summary, score breakdown and related studies → Original source
January 1986 4
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1986-01-01
NON-CHOLINERGIC NEUROTRANSMITTER ABNORMALITIES IN ALZHEIMER'S DISEASE
36/100 ✓ Peer-reviewed Disease mechanisms British Medical Bulletin
Key finding: Apart from the damago to ascending cholinergic projections in Alzheimer's disease, biochemical studies on human brain post mortem have revealed a number of other neurochemical abnormalities.
Full summary, score breakdown and related studies → Original source
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1986-01-01
Postmortem evidence of structural brain changes in schizophrenia. Differences in brain weight, temporal horn area, and parahippocampal gyrus compared with affective disorder
49/100 ✓ Peer-reviewed Getting a diagnosis Archives of general psychiatry
Key finding: From this sample were eliminated the brains of patients whose illnesses did not meet the Washington University criteria for a diagnosis of definite schizophrenia or primary affective disorder and those brains that showed significant histopathologic evidence of Alzheimer's-type change or cerebrovascular disease. +2 more findings
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1986-01-01
Memantine in the treatment of senile dementia of the Alzheimer type
55/100 ✓ Peer-reviewed Treatments Progress in neuro-psychopharmacology & biological psychiatry
Key finding: Statistical evaluation showed no significant differences between the two groups.
Full summary, score breakdown and related studies → Original source
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1986-01-01
Glial fibrillary acidic protein and S-100 protein in human hepatic encephalopathy: immunocytochemical demonstration of dissociation of two glia-associated proteins
40/100 ✓ Peer-reviewed Biomarkers Acta neuropathologica
Key finding: In morphometric comparison, the proportion of GFAP-positive glial cells decreased in the cortex (P less than 0.001) but not significantly in the white matter (0.05 less than P less than 0.1), confirming earlier data that the prominent reduction of GFAP in HE brains is restricted to the grey matter.(
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December 1985 2
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1985-12-01
Neuritic plaques and cerebrovascular amyloid in Alzheimer disease are antigenically related
40/100 ✓ Peer-reviewed Vascular contributions Proceedings of the National Academy of Sciences
Key finding: These findings suggest that the amyloid in neuritic plaques shares antigenic determinants with beta protein of cerebral vessels.
Full summary, score breakdown and related studies → Original source
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1985-12-01
Isolation of HTLV-III from cerebrospinal fluid and neural tissues of patients with neurologic syndromes related to the acquired immunodeficiency syndrome
48/100 ✓ Peer-reviewed Tau biomarkers The New England journal of medicine
Key finding: In one patient, HTLV-III was isolated from the cerebrospinal fluid during acute aseptic meningitis associated with HTLV-III seroconversion. +1 more finding
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November 1985 3
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1985-11-01
The psychosocial and neuropsychiatric sequelae of the acquired immunodeficiency syndrome and related disorders
40/100 ✓ Peer-reviewed Clinical safety Annals of internal medicine
Key finding: The psychological and social impact of AIDS may result in psychiatric symptoms similar to those seen in other life-threatening diseases, including anxiety, depression, and delirium. +1 more finding
Full summary, score breakdown and related studies → Original source
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1985-11-01
Diagnosis of Alzheimer's Disease
58/100 ✓ Peer-reviewed Getting a diagnosis Archives of Neurology
Key finding: To address the problems involved in diagnosing AD in its earliest stages, the National Institute on Aging, the American Association of Retired Persons, the National Institute of Neurological and Communicative Disorders and Stroke, and the National Institute of Mental Health jointly sponsored a workshop for planning research. +4 more findings
Full summary, score breakdown and related studies → Original source
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1985-11-01
Dementia and depression among the elderly living in the Hobart community: the effect of the diagnostic criteria on the prevalence rates
44/100 ✓ Peer-reviewed Cognitive tests and assessment Psychological medicine
Key finding: The prevalence of dementia and of depression was measured by interviewing subjects using a modified version of the Geriatric Mental State Schedule (GMS) (Copeland et al. 1976) and the Mini Mental State Examination (MMSE) (Folstein et al. 1975). +3 more findings
Full summary, score breakdown and related studies → Original source
October 1985 1
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1985-10-01
Subcortical Arteriosclerotic Encephalopathy (Binswanger's Disease)
43/100 ✓ Peer-reviewed Digital health tools Archives of Neurology
Key finding: The necropsy of one patient revealed arteriosclerotic vasculopathy characteristic of subcortical arteriosclerotic encephalopathy (SAE) or Binswanger's disease.
Full summary, score breakdown and related studies → Original source
September 1985 3
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1985-09-01
The suprachiasmatic nucleus of the human brain in relation to sex, age and senile dementia
45/100 ✓ Peer-reviewed Risk factors Brain research
Key finding: Immunocytochemical staining with anti-vasopressin as a marker permitted a morphometric study of this nucleus in the human brain, which revealed that the shape of the SCN is sexually dimorphic.
Full summary, score breakdown and related studies → Original source
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1985-09-01
Empty speech in Alzheimer's disease and fluent aphasia
41/100 ✓ Peer-reviewed Digital health tools Journal of speech and hearing research
Key finding: Our findings may be useful clinically for distinguishing these different patient groups.
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1985-09-01
Measurement of GFAP in hepatic encephalopathy by ELISA and transblots
38/100 ✓ Peer-reviewed Biomarkers Journal of neuropathology and experimental neurology
Key finding: Both methods revealed a 70% decrease in the average amount of GFAP in the cerebral cortex and a 60% decrease in the basal ganglia in HE cases. +3 more findings
Full summary, score breakdown and related studies → Original source
July 1985 1
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1985-07-01
Alzheimer's disease in Down's syndrome: clinicopathologic studies
61/100 ✓ Peer-reviewed Getting a diagnosis Neurology
Key finding: The morphometric observations of the brains of these seven patients with AD showed that the numbers of plaques and tangles exceeded 20 per 1.5 X 10(6) microns2 area, in both the prefrontal and hippocampal cortices. +2 more findings
Full summary, score breakdown and related studies → Original source
June 1985 1
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1985-06-01
Amyloid plaque core protein in Alzheimer disease and Down syndrome
56/100 ✓ Peer-reviewed Down syndrome and Alzheimer's Proceedings of the National Academy of Sciences of the United States of America
Key finding: We have purified and characterized the cerebral amyloid protein that forms the plaque core in Alzheimer disease and in aged individuals with Down syndrome. +4 more findings
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May 1985 3
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1985-05-01
Cholinergic correlates of cognitive impairment in Parkinson's disease: comparisons with Alzheimer's disease
40/100 ✓ Peer-reviewed Brain scans and imaging Journal of Neurology Neurosurgery & Psychiatry
Key finding: We found that the relationship between activity in frontal eye field and eye kinematics varied: the eye speed sensitivity was larger for the different reward conditions than for the different target speed conditions.
Full summary, score breakdown and related studies → Original source
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1985-05-01
Hypersensitivity to ionizing radiation in cultured cells from Down syndrome patients
35/100 ✓ Peer-reviewed Down syndrome and Alzheimer's Journal of the neurological sciences
Key finding: Lines from the four Down syndrome patients were more sensitive to X-rays than lines from 28 normal donors (P = 10(-4)), while survival of the Down syndrome lines after ultraviolet irradiation was not significantly different from normal.
Full summary, score breakdown and related studies → Original source
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1985-05-01
Language disintegration in dementia: effects of etiology and severity
43/100 ✓ Peer-reviewed Digital health tools Brain and language
Key finding: The speech characteristics on a standardized picture description task of 26 subjects with presumed senile dementia of the Alzheimer type (SDAT) and 13 subjects with stroke-related dementia (SRD) were compared to 15 normal subjects over age 59 years. +4 more findings
Full summary, score breakdown and related studies → Original source
April 1985 3
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1985-04-01
Atypical presentation of progressive supranuclear palsy
40/100 ✓ Peer-reviewed Digital health tools Annals of Neurology
Key finding: Four pathologically documented cases of progressive supranuclear palsy are reported. +3 more findings
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1985-04-01
Delirium and other organic mental disorders in a general hospital
45/100 ✓ Peer-reviewed Clinical safety General hospital psychiatry
Key finding: The authors analyze 133 cases of organic mental disorders (OMDs) from a total of 771 patients who were referred for psychiatric consultation from a general hospital. +3 more findings
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1985-04-01
The meaning of cognitive impairment in the elderly
53/100 ✓ Peer-reviewed How common it is Journal of the American Geriatrics Society
Key finding: Ninety-six per cent of the population aged 18-64 scored 23 or higher, whereas 80 per cent of the population 65 and over scored 23 or higher. +4 more findings
Full summary, score breakdown and related studies → Original source
March 1985 1
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1985-03-01
Maternally inherited mitochondrial myopathy and myoclonic epilepsy
40/100 ✓ Peer-reviewed Clinical safety Annals of neurology
Key finding: A family is described with familial myoclonic epilepsy associated with mitochondrial myopathy.
Full summary, score breakdown and related studies → Original source
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