Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 18,501–18,525 of 27,380 studies, newest first · page 741 of 1096.
August 2013 4
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2013-08-01
Poor Sleep as a Precursor to Cognitive Decline in Down Syndrome : A Hypothesis
40/100 ✓ Peer-reviewed Down syndrome and Alzheimer's Journal of Alzheimer's disease & Parkinsonism
Key finding: We propose that sleep disruption is a lever arm that influences how cognition emerges in development and then declines in response to Alzheimer disease in people with Down syndrome. +2 more findings
Full summary, score breakdown and related studies → Original source
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2013-08-01
Glucose levels and risk of dementia
67/100 ✓ Peer-reviewed Prevention and risk The New England journal of medicine
Key finding: Our results suggest that higher glucose levels may be a risk factor for dementia, even among persons without diabetes. +3 more findings
Full summary, score breakdown and related studies → Original source
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2013-08-01
Effect of apolipoprotein E genotype and diet on apolipoprotein E lipidation and amyloid peptides: randomized clinical trial
67/100 ✓ Peer-reviewed Genetics JAMA neurology
Key finding: Baseline levels of LD Aβ were greater for adults with mild cognitive impairment compared with adults with normal cognition (LD Aβ42, P = .05; LD Aβ40, P = .01). +2 more findings
Full summary, score breakdown and related studies → Original source
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2013-08-01
Neuroimaging predictors of brain amyloidosis in mild cognitive impairment
52/100 ✓ Peer-reviewed Biomarkers Annals of neurology
Key finding: As one of the first attempts to use an imaging technique that does not require amyloid-specific radioligands for identification of individuals with brain amyloidosis, our findings could lead to development of multidisciplinary/multimodality brain amyloidosis biomarkers that are reliable, minimally invasive, and widely available. +2 more findings
Full summary, score breakdown and related studies → Original source
July 2013 21
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2013-07-31
Caregiver burden and needs in frontotemporal dementia
45/100 ✓ Peer-reviewed Caregiving Journal of geriatric psychiatry and neurology
Key finding: It appears that changes in the patients' behavior and in the interpersonal relations between caregivers and patients are associated with caregiver depression. +3 more findings
Full summary, score breakdown and related studies → Original source
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2013-07-31
A prospective 14-year longitudinal follow-up of dementia in persons with Down syndrome
36/100 ✓ Peer-reviewed Down syndrome and Alzheimer's Journal of intellectual disability research : JIDR
Key finding: The previously reported high risk levels for dementia among people with Down syndrome was confirmed in these data as was the value of the instruments utilised in tracking decline and helping to confirm diagnosis even in persons with severe intellectual disability. +2 more findings
Full summary, score breakdown and related studies → Original source
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2013-07-31
Glycogen synthase kinase-3 inhibitors: Rescuers of cognitive impairments
36/100 ✓ Peer-reviewed Down syndrome and Alzheimer's Pharmacology & therapeutics
Key finding: These findings demonstrate that GSK3 inhibitors are able to ameliorate cognitive impairments caused by a diverse array of diseases, injury, and treatments. +1 more finding
Full summary, score breakdown and related studies → Original source
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2013-07-31
Dying with dementia: symptoms, treatment, and quality of life in the last week of life
36/100 ✓ Peer-reviewed End-of-life care Journal of pain and symptom management
Key finding: Symptoms are common in dementia at the end of life, despite the large majority of residents receiving opioids. +2 more findings
Full summary, score breakdown and related studies → Original source
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2013-07-31
Cerebrospinal fluid inflammatory markers in Parkinson's disease--associations with depression, fatigue, and cognitive impairment
52/100 ✓ Peer-reviewed Inflammation and the immune system Brain, behavior, and immunity
Key finding: The aim of this study was to measure inflammatory markers in cerebrospinal fluid (CSF) samples from PD patients and a reference group, and to investigate correlations between non-motor symptoms and inflammation. +3 more findings
Full summary, score breakdown and related studies → Original source
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2013-07-31
Non-Alzheimer neurodegenerative pathologies and their combinations are more frequent than commonly believed in the elderly brain: a community-based autopsy series
57/100 ✓ Peer-reviewed Brain tissue and pathology Acta neuropathologica
Key finding: The major proteins are amyloid-β (Aβ), tau, α-synuclein, and TDP-43. +3 more findings
Full summary, score breakdown and related studies → Original source
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2013-07-31
Anemia and risk of dementia in older adults: findings from the Health ABC study
61/100 ✓ Peer-reviewed Disparities Neurology
Key finding: Among older adults, anemia is associated with an increased risk of developing dementia. +4 more findings
Full summary, score breakdown and related studies → Original source
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2013-07-31
Parkinson's disease dementia: convergence of α-synuclein, tau and amyloid-β pathologies
54/100 ✓ Peer-reviewed Getting a diagnosis Nature reviews. Neuroscience
Key finding: Dementia is increasingly being recognized in cases of Parkinson's disease (PD); such cases are termed PD dementia (PDD). +3 more findings
Full summary, score breakdown and related studies → Original source
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2013-07-29
Energetic cost of brain functional connectivity
36/100 ✓ Peer-reviewed Brain scans and imaging Proceedings of the National Academy of Sciences of the United States of America
Key finding: Higher glucose metabolism was associated with proportionally larger MRI signal amplitudes, and a higher degree of connectivity was associated with nonlinear increases in metabolism, supporting our hypothesis for the energy efficiency of the connectivity hubs. +1 more finding
Full summary, score breakdown and related studies → Original source
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2013-07-29
Association of visit-to-visit variability in blood pressure with cognitive function in old age: prospective cohort study
66/100 ✓ Peer-reviewed Hippocampus size on brain scans BMJ (Clinical research ed.)
Key finding: Higher visit-to-visit variability in blood pressure independent of average blood pressure was associated with impaired cognitive function in old age. +2 more findings
Full summary, score breakdown and related studies → Original source
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2013-07-29
A blood based 12-miRNA signature of Alzheimer disease patients
58/100 ✓ Peer-reviewed Getting a diagnosis Genome biology
Key finding: The data indicate that deregulated miRNAs in blood might be used as biomarkers in the diagnosis of AD or other neurological diseases. +1 more finding
Full summary, score breakdown and related studies → Original source
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2013-07-27
Increased risk of dementia in people with previous exposure to general anesthesia: a nationwide population-based case-control study
52/100 ✓ Peer-reviewed Digital health tools Alzheimer's & dementia : the journal of the Alzheimer's Association
Key finding: A history of previous exposure to surgery under GA might be associated with an increased risk of dementia, particularly in subjects who have undergone repeated exposure to GA. +1 more finding
Full summary, score breakdown and related studies → Original source
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2013-07-27
Diet, cognition, and Alzheimer's disease: food for thought
46/100 ✓ Peer-reviewed Prevention and risk European journal of nutrition
Key finding: The prevention of Alzheimer's disease (AD) has become a real challenge due to its rising prevalence and the lack of an effective cure. +2 more findings
Full summary, score breakdown and related studies → Original source
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2013-07-26
Using resting state functional connectivity to unravel networks of tinnitus
36/100 ✓ Peer-reviewed Risk factors Hearing research
Key finding: Evidence from several studies has begun to suggest that tinnitus causes consistent modifications to these networks, including greater connectivity between limbic areas and cortical networks not traditionally involved with emotion processing, and increased connectivity between attention and auditory processing brain regions.
Full summary, score breakdown and related studies → Original source
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2013-07-26
How early can we predict Alzheimer's disease using computational anatomy?
52/100 ✓ Peer-reviewed Digital health tools Neurobiology of aging
Key finding: The obtained classifier was significantly above the chance level (62%) for detecting AD already 4 years before conversion from MCI. +3 more findings
Full summary, score breakdown and related studies → Original source
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2013-07-26
Risk factors for dementia with Lewy bodies: a case-control study
58/100 ✓ Peer-reviewed Genetics Neurology
Key finding: Smoking and education, which have opposing risk effects on AD and PD, are not risk factors for DLB; however, depression and low caffeine intake, both risk factors for AD and PD, increase risk of DLB more strongly than in either. +1 more finding
Full summary, score breakdown and related studies → Original source
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2013-07-25
Oxidative stress and the pathogenesis of Alzheimer's disease
40/100 ✓ Peer-reviewed Disease mechanisms Oxidative medicine and cellular longevity
Key finding: Growing evidence has demonstrated that oxidative stress is an important factor contributing to the initiation and progression of AD. +1 more finding
Full summary, score breakdown and related studies → Original source
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2013-07-25
A literature review of spaced-retrieval interventions: a direct memory intervention for people with dementia
45/100 ✓ Peer-reviewed Prevention trials International psychogeriatrics
Key finding: Current evidence indicates that spaced-retrieval training is effective in enabling people with dementia to learn new information and behavioral strategies. +2 more findings
Full summary, score breakdown and related studies → Original source
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2013-07-25
Determinants for undetected dementia and late-life depression
47/100 ✓ Peer-reviewed Disparities The British journal of psychiatry : the journal of mental science
Key finding: Older adults in China have high levels of undetected dementia and depression. +4 more findings
Full summary, score breakdown and related studies → Original source
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2013-07-25
Genetics of Alzheimer's disease in Caribbean Hispanic and African American populations
42/100 ✓ Peer-reviewed Disparities Biological psychiatry
Key finding: This review summarizes the current knowledge on genetic risk factors associated with LOAD risk in Caribbean Hispanics and African Americans and provides suggestions for future research. +1 more finding
Full summary, score breakdown and related studies → Original source
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2013-07-25
Therapeutics of Alzheimer's disease: Past, present and future
47/100 ✓ Peer-reviewed Caregiving Neuropharmacology
Key finding: The extensive insight into the molecular and cellular pathomechanism in AD over the past few decades has provided us significant progress in the understanding of the disease. +1 more finding
Full summary, score breakdown and related studies → Original source
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