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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 17,651–17,675 of 27,380 studies, newest first · page 707 of 1096.

September 2014 5

  1. 2014-09-03

    The rare TREM2 R47H variant exerts only a modest effect on Alzheimer disease risk

    ✓ Peer-reviewed TREM2 and immune genetics Neurology

    Key finding: Meta-analysis of the 2 family-based and the 5 case-control cohorts yielded a p value of 0.0029, while the overall summary estimate (using case-control data only) resulted in an odds ratio of 1.67 (95% confidence interval 0.95-2.92) for the association between the TREM2 R47H and increased AD risk. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2014-09-02

    Delirium in patients with cancer: assessment, impact, mechanisms and management

    ✓ Peer-reviewed Clinical safety Nature reviews. Clinical oncology

    Key finding: The communicative impediments associated with delirium generate distress for the patient and their family, and substantive challenges for health-care practitioners, who might have to contend with agitation, and difficulty in assessing pain and other symptoms. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2014-09-01

    Adipokines: a link between obesity and dementia?

    ✓ Peer-reviewed Brain tissue and pathology The Lancet. Neurology

    Key finding: This observation leads us to question what it is about body-mass index that is associated with health of the brain and dementia risk. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2014-09-01

    English Longitudinal Study of Aging: can Internet/E-mail use reduce cognitive decline?

    ✓ Peer-reviewed Digital health tools The journals of gerontology. Series A, Biological sciences and medical sciences

    Key finding: Digital literacy may help reduce cognitive decline among persons aged between 50 and 89 years. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2014-09-01

    Functional connectivity in autosomal dominant and late-onset Alzheimer disease

    ✓ Peer-reviewed Brain scans and imaging JAMA neurology

    Key finding: Resting-state functional connectivity magnetic resonance imaging changes with progressing AD severity are similar between ADAD and LOAD. +1 more finding

    Full summary, score breakdown and related studies → Original source

August 2014 20

  1. 2014-08-30

    Higher homocysteine associated with thinner cortical gray matter in 803 participants from the Alzheimer's Disease Neuroimaging Initiative

    ✓ Peer-reviewed Long-term cohort studies Neurobiology of aging

    Key finding: One such risk factor, high-homocysteine levels in the blood, is known to increase risk for Alzheimer's disease and vascular disorders. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2014-08-29

    Predictors of dementia in Parkinson disease: a prospective cohort study

    ✓ Peer-reviewed How common it is Neurology

    Key finding: Cardiovascular autonomic dysfunction, REM sleep behavior disorder, color discrimination ability, and gait dysfunction strongly predict development of dementia in Parkinson disease.

    Full summary, score breakdown and related studies → Original source

  3. 2014-08-28

    The role of PI3K/AKT/mTOR pathway in the modulation of autophagy and the clearance of protein aggregates in neurodegeneration

    ✓ Peer-reviewed Disease mechanisms Cellular signalling

    Key finding: Therefore, induction of autophagy has been proposed as a reasonable strategy to help neurons clear abnormal protein aggregates and survive. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2014-08-28

    Random Forest ensembles for detection and prediction of Alzheimer's disease with a good between-cohort robustness

    ✓ Peer-reviewed Long-term cohort studies NeuroImage. Clinical

    Key finding: In this context, assessment of models' robustness to noise and imaging protocol differences together with post-processing and tuning strategies are key tasks to be addressed in order to move towards successful clinical applications. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2014-08-28

    Sensor-derived physical activity parameters can predict future falls in people with dementia

    ✓ Peer-reviewed Digital health tools Gerontology

    Key finding: Surprisingly, fallers and non-fallers did not differ on any conventional assessment (p = 0.069-0.991), except for 'previous faller' (p = 0.006). +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2014-08-27

    Apolipoprotein E: structure and function in lipid metabolism, neurobiology, and Alzheimer's diseases

    ✓ Peer-reviewed Genetics Neurobiology of disease

    Key finding: Elucidation of the functional domains within this protein and of the three-dimensional structure of the major isoforms of apoE has contributed significantly to our understanding of its physiological and pathophysiological roles at a molecular level.

    Full summary, score breakdown and related studies → Original source

  7. 2014-08-26

    Subjective cognitive complaints contribute to misdiagnosis of mild cognitive impairment

    ✓ Peer-reviewed Mild cognitive impairment Journal of the International Neuropsychological Society : JINS

    Key finding: Cluster analysis revealed Amnestic and Mixed cognitive phenotypes as well as a third Cluster-Derived Normal subgroup (41.3%), whose neuropsychological and cerebrospinal fluid (CSF) Alzheimer's disease (AD) biomarker profiles did not differ from a "robust" normal control group. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2014-08-25

    Dysregulation of protein trafficking in neurodegeneration

    ✓ Peer-reviewed Down syndrome and Alzheimer's Molecular neurodegeneration

    Key finding: DS patients display a strikingly similar pathology to AD patients, including the generation of neuronal amyloid plaques. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2014-08-25

    The benefits associated with volunteering among seniors: a critical review and recommendations for future research

    ✓ Peer-reviewed Prevention and risk Psychological bulletin

    Key finding: There is an urgent need to identify lifestyle activities that reduce functional decline and dementia associated with population aging. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2014-08-24

    Glucose regulation, cognition, and brain MRI in type 2 diabetes: a systematic review

    ✓ Peer-reviewed Risk factors The lancet. Diabetes & endocrinology

    Key finding: Type 2 diabetes is associated with cognitive dysfunction and structural brain changes. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2014-08-23

    R47H TREM2 variant increases risk of typical early-onset Alzheimer's disease but not of prion or frontotemporal dementia

    ✓ Peer-reviewed TREM2 and immune genetics Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: We confirm only p.R47H as a risk factor for AD (odds ratio or OR = 2.19; 95% confidence interval or CI = 1.04-4.51; P = .03). p.R47H does not significantly alter risk for frontotemporal dementia (OR = 0.81), variant or sporadic CJD (OR = 1.06 95%CI = 0.66-1.69) in our cohorts. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2014-08-21

    Automated quantification of 18F-flutemetamol PET activity for categorizing scans as negative or positive for brain amyloid: concordance with visual image reads

    ✓ Peer-reviewed Brain scans and imaging Journal of nuclear medicine : official publication, Society of Nuclear Medicine

    Key finding: The derived threshold was used to categorize the 172 scans in the test cohort as negative or positive, and results were compared with categorization using visual assessment. +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2014-08-20

    Montreal Cognitive Assessment (MoCA)-Italian version: regression based norms and equivalent scores

    ✓ Peer-reviewed Cognitive tests and assessment Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

    Key finding: In this study we report normative data on the MoCA-Italian version, collected on a sample of 225 Italian healthy subjects ranged in age between 60 and 80 years, and in formal education from 5 to 23 years. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2014-08-20

    An investigation of the molecular mechanisms engaged before and after the development of Alzheimer disease neuropathology in Down syndrome: a proteomics approach

    ✓ Peer-reviewed Down syndrome and Alzheimer's Free radical biology & medicine

    Key finding: DS is also associated with the development of Alzheimer disease (AD) neuropathology after the age of 40 years. +2 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2014-08-17

    Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci

    ✓ Peer-reviewed Genetics Nature neuroscience

    Key finding: We found that the level of methylation at 71 of the 415,848 interrogated CpGs was significantly associated with the burden of AD pathology, including CpGs in the ABCA7 and BIN1 regions, which harbor known AD susceptibility variants. +1 more finding

    Full summary, score breakdown and related studies → Original source

  16. 2014-08-15

    Dynamic changes in pro- and anti-inflammatory cytokines in microglia after PPAR-γ agonist neuroprotective treatment in the MPTPp mouse model of progressive Parkinson's disease

    ✓ Peer-reviewed Inflammation and the immune system Neurobiology of disease

    Key finding: Recent findings have suggested that activated microglia may polarize similarly to peripheral macrophages in the central nervous system (CNS), assuming a pro-inflammatory M1 phenotype or the alternative anti-inflammatory M2 phenotype via cytokine production. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2014-08-15

    Worsening cognitive impairment and neurodegenerative pathology progressively increase risk for delirium

    ✓ Peer-reviewed Cognitive tests and assessment The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    Key finding: Delirium is a profound neuropsychiatric disturbance precipitated by acute illness. +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2014-08-15

    A validation study of the Hong Kong version of Montreal Cognitive Assessment (HK-MoCA) in Chinese older adults in Hong Kong

    ✓ Peer-reviewed Cognitive tests and assessment Hong Kong medical journal = Xianggang yi xue za zhi

    Key finding: Cognition clinic and memory clinic of a public hospital in Hong Kong. +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2014-08-15

    Identification of preclinical Alzheimer's disease by a profile of pathogenic proteins in neurally derived blood exosomes: A case-control study

    ✓ Peer-reviewed Lewy body dementia Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Levels of P-S396-tau, P-T181-tau, and Aβ1-42 in extracts of neurally derived blood exosomes predict the development of AD up to 10 years before clinical onset. +1 more finding

    Full summary, score breakdown and related studies → Original source

  20. 2014-08-14

    Long-term systemic inflammation and cognitive impairment in a population-based cohort

    ✓ Peer-reviewed Risk factors Journal of the American Geriatrics Society

    Key finding: With data collected over 20 years, this study demonstrated greater likelihood of cognitive impairment in individuals with repeated high or increasing IL-6. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →