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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 20,776–20,800 of 27,380 studies, newest first · page 832 of 1096.

June 2010 10

  1. 2010-06-01

    Cerebrospinal fluid abnormalities and rate of decline in everyday function across the dementia spectrum: normal aging, mild cognitive impairment, and Alzheimer disease

    ✓ Peer-reviewed Tau biomarkers Archives of neurology

    Key finding: Immunoassays of total tau (t-tau), tau phosphorylated at threonine 181 (p-tau(181)), and beta-amyloid 1-42 (Abeta(42)) concentrations were performed in CSF obtained from participants in the Alzheimer's Disease Neuroimaging Initiative. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2010-06-01

    Anesthetic sevoflurane causes neurotoxicity differently in neonatal naïve and Alzheimer disease transgenic mice

    ✓ Peer-reviewed Risk genes beyond APOE Anesthesiology

    Key finding: Recent studies have suggested that children undergoing surgery under anesthesia could be at an increased risk for the development of learning disabilities, but whether anesthetics contribute to this learning disability is unclear. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2010-06-01

    Posttraumatic stress disorder and risk of dementia among US veterans

    ✓ Peer-reviewed How common it is Archives of general psychiatry

    Key finding: The mean baseline age of the veterans was 68.8 years, and 174 806 (96.5%) were men. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2010-06-01

    Cognitive dysfunction in HIV patients despite long-standing suppression of viremia

    ✓ Peer-reviewed How common it is AIDS (London, England)

    Key finding: Patients had undetectable HIV-1 RNA concentrations for a median time of 48 months (range 3.2-136.6).

    Full summary, score breakdown and related studies → Original source

  5. 2010-06-01

    Dementia with Lewy bodies and Alzheimer disease: neurodegenerative patterns characterized by DTI

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: Increased amygdalar diffusivity in the absence of tissue loss in dementia with Lewy bodies (DLB) may be related to microvacuolation, a common pathology associated with Lewy body disease in the amygdala. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2010-06-01

    Validation of the new interpretive guidelines for the clinical dementia rating scale sum of boxes score in the national Alzheimer's coordinating center database

    ✓ Peer-reviewed Getting a diagnosis Archives of neurology

    Key finding: These findings cross-validate the previously published CDR-SB interpretative guidelines for staging dementia severity and extend those findings to a large heterogeneous sample of patients with dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2010-06-01

    Cognitive deficits and associated neurological complications in individuals with Down's syndrome

    ✓ Peer-reviewed Getting a diagnosis The Lancet. Neurology

    Key finding: Seizures are associated with cognitive decline and seem to cause additional decline in cognitive functioning, particularly in people with Down's syndrome and comorbid disorders such as autism. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2010-06-01

    Probing the biology of Alzheimer's disease in mice

    ✓ Peer-reviewed Getting a diagnosis Neuron

    Key finding: We will argue that transgenic mice expressing amyloid precursor protein should be considered models of accelerated brain aging or asymptomatic AD, and the results of interventional studies in these mice should be considered in the context of primary prevention.

    Full summary, score breakdown and related studies → Original source

  9. 2010-06-01

    Age-varying association between statin use and incident Alzheimer's disease

    ✓ Peer-reviewed Genetics Journal of the American Geriatrics Society

    Key finding: This enlarged study confirms earlier findings that statin therapy in early old age, but not in late age, may be associated with a lower risk of AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2010-06-01

    Genetic variation and neuroimaging measures in Alzheimer disease

    ✓ Peer-reviewed Genetics Archives of neurology

    Key finding: Furthermore, neuroimaging analysis identified 2 additional loci of high interest for further study.

    Full summary, score breakdown and related studies → Original source

May 2010 15

  1. 2010-05-31

    Characterization of the 3xTg-AD mouse model of Alzheimer's disease: part 1. Circadian changes

    ✓ Peer-reviewed Disease mechanisms Brain research

    Key finding: Both male and female 3xTg-AD mice demonstrated alterations to their circadian pacemaker with decreased nocturnal behavior when compared to controls. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2010-05-30

    Phosphorylated TDP-43 pathology and hippocampal sclerosis in progressive supranuclear palsy

    ✓ Peer-reviewed Disease mechanisms Acta neuropathologica

    Key finding: However, several studies have suggested that cases of progressive supranuclear palsy (PSP) lack TDP-43 pathology. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2010-05-29

    Anterior insula degeneration in frontotemporal dementia

    ✓ Peer-reviewed Digital health tools Brain structure & function

    Key finding: The frontotemporal dementias selectively target these large-scale systems, leading to at least three distinct clinical syndromes. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2010-05-28

    Trehalose ameliorates dopaminergic and tau pathology in parkin deleted/tau overexpressing mice through autophagy activation

    ✓ Peer-reviewed Disease mechanisms Neurobiology of disease

    Key finding: The autophagy markers in the brain, the autophagic vacuoles isolated from the liver, and the electron microscopy data indicate that these effects of trehalose are mediated by autophagy.

    Full summary, score breakdown and related studies → Original source

  5. 2010-05-27

    Reviews: developing culturally sensitive dementia caregiver interventions: are we there yet?

    ✓ Peer-reviewed Caregiving American journal of Alzheimer's disease and other dementias

    Key finding: Despite evidence of ethnic differences in family caregivers' experiences, the extent to which caregiver interventions are culturally tailored to address these differences is unknown.

    Full summary, score breakdown and related studies → Original source

  6. 2010-05-26

    Homodimerization is essential for the receptor for advanced glycation end products (RAGE)-mediated signal transduction

    ✓ Peer-reviewed Disease mechanisms The Journal of biological chemistry

    Key finding: Recent fluorescence resonance energy transfer evidence indicates that RAGE may form oligomers on the cell surface and that this could be related to signal transduction. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2010-05-26

    T cells specifically targeted to amyloid plaques enhance plaque clearance in a mouse model of Alzheimer's disease

    ✓ Peer-reviewed TREM2 and immune genetics PloS one

    Key finding: Here, we examine whether Abeta vaccination can facilitate the migration of T lymphocytes to specifically target Abeta plaques and consequently enhance their removal. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2010-05-22

    Vegetables, unsaturated fats, moderate alcohol intake, and mild cognitive impairment

    ✓ Peer-reviewed Prevention and risk Dementia and geriatric cognitive disorders

    Key finding: Vegetables, unsaturated fats, and a high MeDi score may be beneficial to cognitive function.

    Full summary, score breakdown and related studies → Original source

  9. 2010-05-21

    Timing and risk factors for functional changes associated with medical hospitalization in older patients

    ✓ Peer-reviewed Clinical safety The journals of gerontology. Series A, Biological sciences and medical sciences

    Key finding: Most decline occurred prior to hospitalization and was associated with common indicators of poor outcomes in hospitalized elders. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2010-05-21

    Effects of rivastigmine transdermal patch and capsule on aspects of clinical global impression of change in Alzheimer's disease: a retrospective analysis

    ✓ Peer-reviewed Treatments Dementia and geriatric cognitive disorders

    Key finding: Cognitive alterations show greatest correlation with total CGIC. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2010-05-20

    FUS pathology defines the majority of tau- and TDP-43-negative frontotemporal lobar degeneration

    ✓ Peer-reviewed Brain tissue and pathology Acta neuropathologica

    Key finding: This FTLD-FUS collection specifically focussed on aFTLD-U cases, one of three recently defined subtypes of FTLD-FUS. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2010-05-20

    Midlife psychological stress and risk of dementia: a 35-year longitudinal population study

    ✓ Peer-reviewed Brain tissue and pathology Brain : a journal of neurology

    Key finding: Nevertheless, the pathogeneses of these diseases are not sufficiently understood. +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2010-05-20

    Unintended effects of statins in men and women in England and Wales: population based cohort study using the QResearch database

    ✓ Peer-reviewed How common it is BMJ (Clinical research ed.)

    Key finding: Individual statins were not significantly associated with risk of Parkinson's disease, rheumatoid arthritis, venous thromboembolism, dementia, osteoporotic fracture, gastric cancer, colon cancer, lung cancer, melanoma, renal cancer, breast cancer, or prostate cancer. +2 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2010-05-18

    TREM2- and DAP12-dependent activation of PI3K requires DAP10 and is inhibited by SHIP1

    ✓ Peer-reviewed TREM2 and immune genetics Science signaling

    Key finding: TREM2 (triggering receptor expressed on myeloid cells-2) is the main DAP12-associated receptor in osteoclasts and, similar to DAP12 deficiency, loss of TREM2 in humans leads to Nasu-Hakola disease, which is characterized by bone cysts and dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2010-05-18

    Ubiquitin regulates GGA3-mediated degradation of BACE1

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: The BACE1 C-terminal fragment contains a DXXLL motif that has been shown to bind the VHS (VPS27, Hrs, and STAM) domain of GGA1-3 (Golgi-localized gamma-ear-containing ARF-binding proteins). +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →