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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 19,601–19,625 of 27,380 studies, newest first · page 785 of 1096.

March 2012 17

  1. 2012-03-05

    Curcumin loaded-PLGA nanoparticles conjugated with Tet-1 peptide for potential use in Alzheimer's disease

    ✓ Peer-reviewed Treatments PloS one

    Key finding: Our results suggest that curcumin encapsulated-PLGA nanoparticles are able to destroy amyloid aggregates, exhibit anti-oxidative property and are non-cytotoxic.

    Full summary, score breakdown and related studies → Original source

  2. 2012-03-05

    Phenolic compounds prevent amyloid β-protein oligomerization and synaptic dysfunction by site-specific binding

    ✓ Peer-reviewed Disease mechanisms The Journal of biological chemistry

    Key finding: Cerebral deposition of amyloid β protein (Aβ) is an invariant feature of Alzheimer disease (AD), and epidemiological evidence suggests that moderate consumption of foods enriched with phenolic compounds reduce the incidence of AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2012-03-04

    Cognitive activity, education and socioeconomic status as preventive factors for mild cognitive impairment and Alzheimer's disease

    ✓ Peer-reviewed Disparities Psychiatry research

    Key finding: Growing epidemiological evidence suggests that premorbid participation in cognitive leisure activities (CLA) reduces the risk of dementia by increasing cognitive reserve. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2012-03-03

    Voxelwise meta-analysis of gray matter anomalies in Alzheimer's disease and mild cognitive impairment using anatomic likelihood estimation

    ✓ Peer-reviewed Mild cognitive impairment Journal of the neurological sciences

    Key finding: Our meta-analysis identified similar distributions of neuroanatomical changes in AD and MCI, which are consistent with the hierarchical model of neuropathological alterations of neurofibrillary tangles in AD and MCI. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2012-03-02

    Disability and decline in physical function associated with hospital use at end of life

    ✓ Peer-reviewed End-of-life care Journal of general internal medicine

    Key finding: Functional decline is significantly associated with end-of-life hospital use among older adults. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2012-03-01

    Donepezil and memantine for moderate-to-severe Alzheimer's disease

    ✓ Peer-reviewed Treatments The New England journal of medicine

    Key finding: In patients with moderate or severe Alzheimer's disease, continued treatment with donepezil was associated with cognitive benefits that exceeded the minimum clinically important difference and with significant functional benefits over the course of 12 months. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2012-03-01

    Amygdala and hippocampal volume reductions as candidate endophenotypes for borderline personality disorder: a meta-analysis of magnetic resonance imaging studies

    ✓ Peer-reviewed Hippocampus size on brain scans Psychiatry research

    Key finding: Volumetric magnetic resonance imaging results from 11 studies comprising 205 BPD patients and 222 healthy controls were quantitatively synthesized using meta-analytic techniques. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2012-03-01

    Barriers to providing end-of-life care for people with dementia: a whole-system qualitative study

    ✓ Peer-reviewed End-of-life care BMJ supportive & palliative care

    Key finding: Qualitative methods of service evaluation facilitated a broader and deeper understanding of a range of perspectives, which, with other components of rapid participatory appraisal, generated potential solutions to improve care.

    Full summary, score breakdown and related studies → Original source

  9. 2012-03-01

    Use of medical foods and nutritional approaches in the treatment of Alzheimer's disease

    ✓ Peer-reviewed Prevention trials Clinical practice (London, England)

    Key finding: Axona supplies ketone bodies as alternative energy source to neurons. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2012-03-01

    Clinico-pathological features in amyotrophic lateral sclerosis with expansions in C9ORF72

    ✓ Peer-reviewed Brain tissue and pathology Brain : a journal of neurology

    Key finding: Initial reports indicate that this variant within the frontotemporal dementia/amyotrophic lateral sclerosis spectrum is associated with transactive response DNA binding protein (TDP-43) proteinopathy. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2012-03-01

    Proline isomer-specific antibodies reveal the early pathogenic tau conformation in Alzheimer's disease

    ✓ Peer-reviewed Mild cognitive impairment Cell

    Key finding: However, there is no direct evidence for the existence of cis-trans protein isomers in vivo or for their conformation-specific function or regulation. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2012-03-01

    Frontotemporal dementia with the C9ORF72 hexanucleotide repeat expansion: clinical, neuroanatomical and neuropathological features

    ✓ Peer-reviewed How common it is Brain : a journal of neurology

    Key finding: The neuroimaging profile of the C9ORF72 expansion was significantly more symmetrical than progranulin mutations with significantly less temporal lobe involvement than microtubule-associated protein tau mutations. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2012-03-01

    Characterization of frontotemporal dementia and/or amyotrophic lateral sclerosis associated with the GGGGCC repeat expansion in C9ORF72

    ✓ Peer-reviewed Getting a diagnosis Brain : a journal of neurology

    Key finding: Incomplete penetrance was suggested in two kindreds, and the youngest generation had significantly earlier age of onset (>10 years) compared with the next oldest generation in 11 kindreds. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2012-03-01

    Neuroimaging signatures of frontotemporal dementia genetics: C9ORF72, tau, progranulin and sporadics

    ✓ Peer-reviewed Getting a diagnosis Brain : a journal of neurology

    Key finding: We aimed to determine the regional pattern of brain atrophy associated with the C9ORF72 gene mutation, and to determine which regions best differentiate C9ORF72 from subjects with mutations in tau and progranulin, and from sporadic frontotemporal dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2012-03-01

    Disturbed sleep patterns in elders with mild cognitive impairment: the role of memory decline and ApoE ε4 genotype

    ✓ Peer-reviewed Genetics Current Alzheimer research

    Key finding: Sleep disturbances are prevalent in patients with Alzheimer' disease (AD), being one of the most troubling symptoms during the progression of disease. +2 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2012-03-01

    Low-density lipoprotein receptor represents an apolipoprotein E-independent pathway of Aβ uptake and degradation by astrocytes

    ✓ Peer-reviewed Genetics The Journal of biological chemistry

    Key finding: Deletion of LDLR caused a decrease in Aβ uptake, whereas increasing LDLR levels significantly enhanced both the uptake and clearance of Aβ. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2012-03-01

    Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease

    ✓ Peer-reviewed Genetics Cold Spring Harbor perspectives in medicine

    Key finding: There is substantial evidence that differential effects of apoE isoform on AD risk are influenced by the ability of apoE to affect Aβ aggregation and clearance in the brain. +4 more findings

    Full summary, score breakdown and related studies → Original source

February 2012 8

  1. 2012-02-29

    An epigenetic blockade of cognitive functions in the neurodegenerating brain

    ✓ Peer-reviewed Disease mechanisms Nature

    Key finding: These findings advocate for the development of selective inhibitors of histone deacetylase 2 and suggest that cognitive capacities following neurodegeneration are not entirely lost, but merely impaired by this epigenetic blockade.

    Full summary, score breakdown and related studies → Original source

  2. 2012-02-29

    Staging and natural history of cerebrovascular pathology in dementia

    ✓ Peer-reviewed Caregiving Neurology

    Key finding: A staging system based on this conceptual model of cerebrovascular pathology could enable the neuropathologic quantification of the cerebrovascular burden in dementia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2012-02-28

    Cerebral hemodynamics and incident depression: the Rotterdam Study

    ✓ Peer-reviewed Long-term cohort studies Biological psychiatry

    Key finding: According to the vascular depression hypothesis, subclinical cerebrovascular disease can cause depression in older adults. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2012-02-27

    Advance directives and physicians' orders in nursing home residents with dementia in Flanders, Belgium: prevalence and associated outcomes

    ✓ Peer-reviewed End-of-life care International psychogeriatrics

    Key finding: Nursing home residents receiving palliative care are more likely to have a GP order. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2012-02-27

    Increased risk of cognitive and functional decline in patients with atrial fibrillation: results of the ONTARGET and TRANSCEND studies

    ✓ Peer-reviewed Cognitive tests and assessment CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne

    Key finding: The role of atrial fibrillation in cognitive impairment and dementia, independent of stroke, is uncertain. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2012-02-27

    Interregional correlations in Parkinson disease and Parkinson-related dementia with resting functional MR imaging

    ✓ Peer-reviewed Brain scans and imaging Radiology

    Key finding: PRD was associated with selective disruption of corticostriatal resting functional MR imaging correlations, which suggests that resting functional MR imaging analyzed in subject-native space may be a useful biomarker in this disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2012-02-27

    The role of cognitive impairment in fall risk among older adults: a systematic review and meta-analysis

    ✓ Peer-reviewed Getting a diagnosis Age and ageing

    Key finding: Our objective was to evaluate the epidemiological evidence linking cognitive impairment and fall risk. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2012-02-24

    Usability of a new electronic assistive device for community-dwelling persons with mild dementia

    ✓ Peer-reviewed Digital health tools Aging & mental health

    Key finding: With the suggested adaptations, the CDN is expected to be a useful tool for supporting community-dwelling persons with mild dementia and their carers.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →