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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 18,351–18,375 of 27,380 studies, newest first · page 735 of 1096.

October 2013 25

  1. 2013-10-12

    Controlled cortical impact results in an extensive loss of dendritic spines that is not mediated by injury-induced amyloid-beta accumulation

    ✓ Peer-reviewed Disease mechanisms Journal of neurotrauma

    Key finding: The loss of excitatory synapses could potentially explain why such diverse symptoms occur after TBI, and a recent preclinical study has demonstrated a loss of dendritic spines, the postsynaptic site of the excitatory synapse, after fluid percussion injury. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2013-10-11

    Mediterranean diet habits in older individuals: associations with cognitive functioning and brain volumes

    ✓ Peer-reviewed Prevention trials Experimental gerontology

    Key finding: These observational findings suggest that keeping to a low meat intake could prove to be an impact-driven public health policy to support healthy cognitive aging, when confirmed by longitudinal studies. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2013-10-11

    Triggering receptor expressed on myeloid cells 2 variant is rare in late-onset Alzheimer's disease in Han Chinese individuals

    ✓ Peer-reviewed TREM2 and immune genetics Neurobiology of aging

    Key finding: To date, no study has investigated the association between rare mutations of TREM2 and LOAD risk in non-European population. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2013-10-11

    Biomarker-based prediction of progression in MCI: Comparison of AD signature and hippocampal volume with spinal fluid amyloid-β and tau

    ✓ Peer-reviewed Mild cognitive impairment Frontiers in aging neuroscience

    Key finding: For prediction of dementia in MCI, the AD signature cortical thickness biomarker performed better than hippocampal volume. +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2013-10-10

    Vildagliptin: an anti-diabetes agent ameliorates cognitive deficits and pathology observed in streptozotocin-induced Alzheimer's disease

    ✓ Peer-reviewed Drug development The Journal of pharmacy and pharmacology

    Key finding: These robust therapeutic effects of vildagliptin demonstrate a unique mechanism for Aβ and tau clearance and reverse the cognitive deficits and pathology observed in AD. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2013-10-10

    Meditation's impact on default mode network and hippocampus in mild cognitive impairment: a pilot study

    ✓ Peer-reviewed Hippocampus size on brain scans Neuroscience letters

    Key finding: The results showed that after the intervention, MBSR participants had increased functional connectivity between the posterior cingulate cortex and bilateral medial prefrontal cortex and left hippocampus compared to controls. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2013-10-09

    Brain hemorrhages in cerebral amyloid angiopathy

    ✓ Peer-reviewed Vascular contributions Seminars in thrombosis and hemostasis

    Key finding: CAA-associated vasculopathies, such as microaneurysmal formation with fibrinoid necrosis, underlie such cerebrovascular events. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2013-10-09

    Compassion in healthcare - lessons from a qualitative study of the end of life care of people with dementia

    ✓ Peer-reviewed End-of-life care Journal of the Royal Society of Medicine

    Key finding: The concepts of compassion, kindness and humanity in dementia care are discussed within the paper.

    Full summary, score breakdown and related studies → Original source

  9. 2013-10-09

    Investigating the role of rare heterozygous TREM2 variants in Alzheimer's disease and frontotemporal dementia

    ✓ Peer-reviewed TREM2 and immune genetics Neurobiology of aging

    Key finding: Moreover, a rare TREM2 exon 2 variant (p.R47H) was reported to increase the risk of Alzheimer's disease (AD) with an odds ratio as strong as that for APOEε4. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2013-10-09

    MRI and pathology of REM sleep behavior disorder in dementia with Lewy bodies

    ✓ Peer-reviewed Digital health tools Neurology

    Key finding: Patients with autopsy-confirmed low-, intermediate-, and high-likelihood DLB, according to the probability statement recommended by the third report of the DLB Consortium, and antemortem MRI, were identified (n = 75). +2 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2013-10-09

    Clinical and multimodal biomarker correlates of ADNI neuropathological findings

    ✓ Peer-reviewed Brain scans and imaging Acta neuropathologica communications

    Key finding: Biomarkers can be used to independently predict coincident AD and DLB pathology, a common finding in amnestic MCI and DAT patients.

    Full summary, score breakdown and related studies → Original source

  12. 2013-10-07

    Effect of phosphodiesterase-5 inhibition on apoptosis and beta amyloid load in aged mice

    ✓ Peer-reviewed Biomarkers Neurobiology of aging

    Key finding: Because it has been previously demonstrated that phosphodiesterase-5 inhibitors (PDE5-Is) protect against hippocampal synaptic dysfunction and memory deficits in mouse models of Alzheimer's disease and physiological aging, we investigated the effect of a treatment with the PDE5-I, sildenafil, on cell death, pro- and antiapoptotic molecules, and Aβ production. +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2013-10-07

    Phagocytosis executes delayed neuronal death after focal brain ischemia

    ✓ Peer-reviewed Inflammation and the immune system Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Phagocytic removal of neurons is generally assumed to be beneficial and to occur only after neuronal death. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2013-10-07

    Study design of ASPirin in Reducing Events in the Elderly (ASPREE): a randomized, controlled trial

    ✓ Peer-reviewed Prevention and risk Contemporary clinical trials

    Key finding: Secondary endpoints are all-cause and cause specific mortality, fatal and non-fatal cardiovascular events, fatal and non-fatal cancer (excluding non-melanoma skin cancer), dementia, mild cognitive impairment, depression, physical disability, and clinically significant bleeding. +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2013-10-06

    Psychosis in Alzheimer's disease

    ✓ Peer-reviewed Genetics Biological psychiatry

    Key finding: Neuroimaging studies suggest that AD + P subjects demonstrate greater cortical synaptic impairments than AD subjects without psychosis, reflected in reduced gray matter volume, reduced regional blood flow, and reduced regional glucose metabolism. +2 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2013-10-06

    Cognitive deficits in geriatric depression: clinical correlates and implications for current and future treatment

    ✓ Peer-reviewed Cognitive tests and assessment The Psychiatric clinics of North America

    Key finding: The purpose of this article is to identify the cognitive deficits commonly associated with geriatric depression and describe their clinical significance.

    Full summary, score breakdown and related studies → Original source

  17. 2013-10-06

    Dipeptide repeat protein pathology in C9ORF72 mutation cases: clinico-pathological correlations

    ✓ Peer-reviewed Brain tissue and pathology Acta neuropathologica

    Key finding: Recently, unconventional non-ATG translation of the expanded hexanucleotide repeat, resulting in the production and aggregation of dipeptide repeat (DPR) proteins (poly-GA, -GR and GP), was identified as a potential pathomechanism of C9ORF72 mutations. +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2013-10-05

    Special Care Units and Traditional Care in Dementia: Relationship with Behavior, Cognition, Functional Status and Quality of Life - A Review

    ✓ Peer-reviewed Caregiving Dementia and Geriatric Cognitive Disorders Extra

    Key finding: Our literature search resulted in 32 studies published until October 2012. +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2013-10-03

    Optimizing function and physical activity among nursing home residents with dementia: testing the impact of function-focused care

    ✓ Peer-reviewed Clinical safety The Gerontologist

    Key finding: Purpose of the study The purpose of this study was to test the impact of Function-Focused Care for the Cognitively Impaired Intervention on nursing home residents with dementia and the nursing assistants who care for them. +1 more finding

    Full summary, score breakdown and related studies → Original source

  20. 2013-10-03

    Integrative EEG biomarkers predict progression to Alzheimer's disease at the MCI stage

    ✓ Peer-reviewed Mild cognitive impairment Frontiers in aging neuroscience

    Key finding: Importantly, by integrating six EEG biomarkers into a diagnostic index using logistic regression the prediction improved compared with the classification using the individual biomarkers, with a sensitivity of 88% and specificity of 82%, compared with a sensitivity of 64% and specificity of 62% of the best individual biomarker in this index. +1 more finding

    Full summary, score breakdown and related studies → Original source

  21. 2013-10-02

    Two novel Tau antibodies targeting the 396/404 region are primarily taken up by neurons and reduce Tau protein pathology

    ✓ Peer-reviewed Inflammation and the immune system The Journal of biological chemistry

    Key finding: Recent studies from our group and others have demonstrated that both active and passive immunizations reduce Tau pathology and prevent cognitive decline in transgenic mice. +2 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2013-10-02

    Modeling Alzheimer's Disease Progression Using Disease Onset Time and Disease Trajectory Concepts Applied to CDR-SOB Scores From ADNI

    ✓ Peer-reviewed Long-term cohort studies CPT: pharmacometrics & systems pharmacology

    Key finding: The model enabled the estimation of a DOT and a disease trajectory for each patient. +3 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2013-10-02

    The innate immune system in Alzheimer's disease

    ✓ Peer-reviewed TREM2 and immune genetics International journal of cell biology

    Key finding: It is characterized by two biochemically distinct types of protein aggregates: amyloid β (A β ) peptide in the forms of parenchymal amyloid plaques and congophilic amyloid angiopathy (CAA) and aggregated tau protein in the form of intraneuronal neurofibrillary tangles (NFT). +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2013-10 month only

    [The DIAN study]

    ✓ Peer-reviewed Risk genes beyond APOE Brain and nerve = Shinkei kenkyu no shinpo

    Key finding: The study revealed that the biomarker change, which is the reduction of Aβ42 in the CSF of the carrier's brain, started approximately 15-20 years prior to the onset of symptoms. +1 more finding

    Full summary, score breakdown and related studies → Original source

  25. 2013-10-01

    Long-term cognitive impairment after critical illness

    ✓ Peer-reviewed Risk factors The New England journal of medicine

    Key finding: Patients in medical and surgical ICUs are at high risk for long-term cognitive impairment. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →