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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 17,101–17,125 of 27,380 studies, newest first · page 685 of 1096.

March 2015 25

  1. 2015-03-18

    APOE ‐modulated Aβ‐induced neuroinflammation in Alzheimer's disease: current landscape, novel data, and future perspective

    ✓ Peer-reviewed Inflammation and the immune system Journal of Neurochemistry

    Key finding: APOE 4 is the greatest AD ‐genetic risk factor; increasing risk up to 12‐fold compared to APOE 3, with APOE 4 ‐specific neuroinflammation an important component of this risk. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2015-03-18

    Predicting the risk of mild cognitive impairment in the Mayo Clinic Study of Aging

    ✓ Peer-reviewed Mild cognitive impairment Neurology

    Key finding: We have developed MCI risk scores using variables easily assessable in the clinical setting and that may be useful in routine patient care. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2015-03-17

    Galantamine improves sleep quality in patients with dementia

    ✓ Peer-reviewed Treatments Acta neurologica Belgica

    Key finding: The improvement in sleep quality was better with regard to changes in Pittsburgh Sleep Quality Index scores with galantamine treatment compared to the donepezil and the control groups. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2015-03-17

    DNA methylation of the serotonin transporter gene in peripheral cells and stress-related changes in hippocampal volume: a study in depressed patients and healthy controls

    ✓ Peer-reviewed Hippocampus size on brain scans PloS one

    Key finding: For instance, animal studies have demonstrated that early disruptions in the serotonin system affect brain development and emotion regulation in later life. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2015-03-17

    Community-based palliative care is associated with reduced emergency department use by people with dementia in their last year of life: A retrospective cohort study

    ✓ Peer-reviewed End-of-life care Palliative medicine

    Key finding: Community-based palliative care of people who die with or of dementia is relatively infrequent but associated with significant reductions in hospital emergency department use in the last year of life. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2015-03-17

    The TREM2-DAP12 signaling pathway in Nasu-Hakola disease: a molecular genetics perspective

    ✓ Peer-reviewed TREM2 and immune genetics Research and reports in biochemistry

    Key finding: Here, we review the genetic causes of PLOSL with loss-of-function mutations or deletions in one of two genes, TYROBP and TREM2 , encoding for two proteins DNAX-activating protein 12 (DAP12) and triggering receptor expressed on myeloid cells-2 (TREM2). +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2015-03-17

    A novel Alzheimer disease locus located near the gene encoding tau protein

    ✓ Peer-reviewed Genetics Molecular psychiatry

    Key finding: APOE ɛ4, the most significant genetic risk factor for Alzheimer disease (AD), may mask effects of other loci. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2015-03-16

    Neuroinflammation in Alzheimer's disease

    ✓ Peer-reviewed Inflammation and the immune system The Lancet Neurology

    Full summary, score breakdown and related studies → Original source

  9. 2015-03-13

    Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies

    ✓ Peer-reviewed Disease mechanisms Experimental & molecular medicine

    Key finding: Aggregation-prone substrates resistant to both the UPS and the CMA can be degraded by macroautophagy, in which cargoes are segregated into autophagosomes before degradation by lysosomal hydrolases. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2015-03-13

    Sleep, circadian rhythms, and the pathogenesis of Alzheimer disease

    ✓ Peer-reviewed Brain tissue and pathology Experimental & molecular medicine

    Key finding: Recent evidence demonstrates that sleep-wake and circadian disruption often occur early in the course of the disease and may even precede the development of cognitive symptoms. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2015-03-13

    Insulin resistance as a key link for the increased risk of cognitive impairment in the metabolic syndrome

    ✓ Peer-reviewed Risk factors Experimental & molecular medicine

    Key finding: Insulin resistance (IR) is at the core of MetS and likely represent the key link between MetS and AD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2015-03-13

    Risk factors for neurodegeneration in idiopathic rapid eye movement sleep behavior disorder: a multicenter study

    ✓ Peer-reviewed Prevention and risk Annals of neurology

    Key finding: Of 305 patients, follow-up information was available for 279, of whom 93 (33.3%) developed defined neurodegenerative disease.

    Full summary, score breakdown and related studies → Original source

  13. 2015-03-13

    Dietary patterns, cognitive decline, and dementia: a systematic review

    ✓ Peer-reviewed Prevention and risk Advances in nutrition (Bethesda, Md.)

    Key finding: The results suggest that better adherence to a Mediterranean diet is associated with less cognitive decline, dementia, or Alzheimer disease, as shown by 4 of 6 cross-sectional studies, 6 of 12 longitudinal studies, 1 trial, and 3 meta-analyses. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2015-03-12

    Cerebellum Can Serve As a Pseudo-Reference Region in Alzheimer Disease to Detect Neuroinflammation Measured with PET Radioligand Binding to Translocator Protein

    ✓ Peer-reviewed Inflammation and the immune system Journal of nuclear medicine : official publication, Society of Nuclear Medicine

    Key finding: Alzheimer disease (AD) is associated with an increase in the brain of the 18-kDa translocator protein (TSPO), which is overexpressed in activated microglia and reactive astrocytes. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2015-03-12

    Hippocampal plasticity during the progression of Alzheimer's disease

    ✓ Peer-reviewed Mild cognitive impairment Neuroscience

    Key finding: Neuroplasticity involves molecular and structural changes in central nervous system (CNS) throughout life. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2015-03-12

    Cognitive impairment six months after ischaemic stroke: a profile from the ASPIRE-S study

    ✓ Peer-reviewed Caregiving BMC neurology

    Key finding: Encouragingly, aspects of secondary prevention were identified that may be protective in reducing the incidence of cognitive impairment post-stroke. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2015-03-12

    A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial

    ✓ Peer-reviewed Prevention and risk Lancet (London, England)

    Key finding: Modifiable vascular and lifestyle-related risk factors have been associated with dementia risk in observational studies. +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2015-03-12

    A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial

    ✓ Peer-reviewed Prevention and risk The Lancet

    Key finding: 1,260 adults aged 60-77 with elevated dementia risk scores randomized to 2-year multidomain intervention vs. control (regular health advice) +2 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2015-03-11

    Regulatory Effects of Caffeic Acid Phenethyl Ester on Neuroinflammation in Microglial Cells

    ✓ Peer-reviewed Inflammation and the immune system International Journal of Molecular Sciences

    Key finding: Microglial activation has been widely demonstrated to mediate inflammatory processes that are crucial in several neurodegenerative disorders. +2 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2015-03-11

    Voluntary Running Attenuates Memory Loss, Decreases Neuropathological Changes and Induces Neurogenesis in a Mouse Model of A lzheimer's Disease

    ✓ Peer-reviewed Biomarkers Brain Pathology

    Key finding: It has been suggested that exercise might ameliorate the disease; here, we evaluated the effect of voluntary running on several aspects of AD including amyloid deposition, tau phosphorylation, inflammatory reaction, neurogenesis and spatial memory in the double transgenic APPswe/PS1ΔE9 mouse model of AD. +2 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2015-03-11

    Hearing loss and cognition: the role of hearing AIDS, social isolation and depression

    ✓ Peer-reviewed Risk factors PloS one

    Key finding: Hearing loss is associated with poor cognitive performance and incident dementia and may contribute to cognitive decline. +4 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2015-03-11

    Neuropathologically mixed Alzheimer's and Lewy body disease: burden of pathological protein aggregates differs between clinical phenotypes

    ✓ Peer-reviewed Caregiving Acta neuropathologica

    Key finding: In addition, we investigated cases that were both clinically and neuropathologically diagnosed as either AD (pure AD; n = 5) or DLB/neocortical LBD (pure DLB; n = 4). +4 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2015-03-10

    The role of the tripartite glutamatergic synapse in the pathophysiology of Alzheimer's disease

    ✓ Peer-reviewed Digital health tools Aging and disease

    Key finding: However, the exact mechanism by which these proteins cause neurodegeneration is still not clear. +4 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2015-03-10

    Link between type 2 diabetes and Alzheimer's disease: from epidemiology to mechanism and treatment

    ✓ Peer-reviewed Drug development Clinical interventions in aging

    Key finding: Studies have shown that insulin resistance and deficiency can interact with amyloid-β protein and tau protein phosphorylation, each leading to the onset and development of AD. +1 more finding

    Full summary, score breakdown and related studies → Original source

  25. 2015-03-10

    Cellular Models of Aggregation-dependent Template-directed Proteolysis to Characterize Tau Aggregation Inhibitors for Treatment of Alzheimer Disease

    ✓ Peer-reviewed Disease mechanisms The Journal of biological chemistry

    Key finding: We use these in combination with dissolution of native PHFs to quantify the activity of Tau aggregation inhibitors (TAIs). +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →