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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 18,976–19,000 of 27,380 studies, newest first · page 760 of 1096.

January 2013 25

  1. 2013-01-01

    Current and future treatments for Alzheimer's disease

    ✓ Peer-reviewed Treatments Therapeutic advances in neurological disorders

    Key finding: Three cholinesterase inhibitors (CIs) are currently available and have been approved for the treatment of mild to moderate AD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2013-01-01

    Discovering new treatments for Alzheimer's disease by repurposing approved medications

    ✓ Peer-reviewed Drug development Current topics in medicinal chemistry

    Key finding: We provide a review of the current literature in assessing possibilities of repurposing medications currently used for non-AD indications. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2013-01-01

    Biomarkers of Alzheimer's disease among Mexican Americans

    ✓ Peer-reviewed Drug development Journal of Alzheimer's disease : JAD

    Key finding: The biomarker profile for AD among Mexican American cases is significantly different from that previously identified among non-Hispanic cases from many large-scale studies. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2013-01-01

    The neuroprotection of liraglutide on Alzheimer-like learning and memory impairment by modulating the hyperphosphorylation of tau and neurofilament proteins and insulin signaling pathways in mice

    ✓ Peer-reviewed Drug development Journal of Alzheimer's disease : JAD

    Key finding: The results show that both hyperphosphorylated tau and neurofilament proteins had deceased protein glycosylation and the tau bound to microtubules was lower in the STZ group compared to the CON group. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2013-01-01

    Subcutaneous administration of liraglutide ameliorates Alzheimer-associated tau hyperphosphorylation in rats with type 2 diabetes

    ✓ Peer-reviewed Drug development Journal of Alzheimer's disease : JAD

    Key finding: Our results indicated that subcutaneous administration of liraglutide restores both peripheral and brain insulin sensitivity and ameliorates tau hyperphosphorylation in rats with type 2 diabetes. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2013-01-01

    Genetics of familial and sporadic Alzheimer's disease

    ✓ Peer-reviewed Genetics Frontiers in bioscience (Elite edition)

    Key finding: Genome-wide association studies (GWASs) revealed the genetic complexity of the disease and recent studies suggested that epigenetic mechanisms may play an essential role in disease development.

    Full summary, score breakdown and related studies → Original source

  7. 2013-01-01

    Genetic insights in Alzheimer's disease

    ✓ Peer-reviewed Genetics The Lancet. Neurology

    Key finding: In the search for new genes in Alzheimer's disease, classic linkage-based and candidate-gene-based association studies have been supplanted by exome sequencing, genome-wide sequencing (for mendelian forms of Alzheimer's disease), and genome-wide association studies (for non-mendelian forms). +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2013-01-01

    Alzheimer's disease mutations in APP but not γ-secretase modulators affect epsilon-cleavage-dependent AICD production

    ✓ Peer-reviewed Biomarkers Nature communications

    Key finding: Molecular simulations suggest that familial Alzheimer's disease mutations modulate the flexibility of the APP transmembrane domain and the presentation of its γ-site, modifying at the same time, the solvation of the ε-site.

    Full summary, score breakdown and related studies → Original source

  9. 2013-01-01

    A selected reaction monitoring (SRM)-based method for absolute quantification of Aβ38, Aβ40, and Aβ42 in cerebrospinal fluid of Alzheimer's disease patients and healthy controls

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: The diagnostic performance of the method was evaluated on two independent clinical materials with research volunteers who were cognitively normal and AD patients with mild to moderate dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2013-01-01

    Niemann-Pick diseases

    ✓ Peer-reviewed Clinical safety Handbook of clinical neurology

    Key finding: Systemic manifestations, if present, always precede onset of neurological manifestations. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2013-01-01

    The impact of human-computer interaction-based comprehensive training on the cognitive functions of cognitive impairment elderly individuals in a nursing home

    ✓ Peer-reviewed Prevention trials Journal of Alzheimer's disease : JAD

    Key finding: Human-computer interaction-based comprehensive training may improve cognitive functions among cognitively impaired elderly individuals. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2013-01-01

    Natural cannabinoids improve dopamine neurotransmission and tau and amyloid pathology in a mouse model of tauopathy

    ✓ Peer-reviewed Disease mechanisms Journal of Alzheimer's disease : JAD

    Key finding: Sativex® significantly reduced the intraneuronal, MAO-related free radicals produced during dopamine metabolism in the limbic system.

    Full summary, score breakdown and related studies → Original source

  13. 2013-01-01

    The Diagnosis of Mild Cognitive Impairment due to Alzheimer’s Disease: Recommendations from the National Institute on Aging-Alzheimer’s Association Workgroups on Diagnostic Guidelines for Alzheimer’s Disease

    ✓ Peer-reviewed Mild cognitive impairment FOCUS The Journal of Lifelong Learning in Psychiatry

    Key finding: The workgroup developed the following two sets of criteria: (1) core clinical criteria that could be used by healthcare providers without access to advanced imaging techniques or cerebrospinal fluid analysis, and (2) research criteria that could be used in clinical research settings, including clinical trials. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2013-01-01

    CB2 cannabinoid receptor agonist ameliorates Alzheimer-like phenotype in AβPP/PS1 mice

    ✓ Peer-reviewed Inflammation and the immune system Journal of Alzheimer's disease : JAD

    Key finding: This effect was more pronounced when administered at the pre-symptomatic rather than the early symptomatic stage. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2013-01-01

    Determining the presence of periodontopathic virulence factors in short-term postmortem Alzheimer's disease brain tissue

    ✓ Peer-reviewed Inflammation and the immune system Journal of Alzheimer's disease : JAD

    Key finding: Our request matched 10 AD cases for tissue from Brains for Dementia Research alongside 10 non-AD age-related controls with similar or greater postmortem interval. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2013-01-01

    Inflammation and white matter degeneration persist for years after a single traumatic brain injury

    ✓ Peer-reviewed Inflammation and the immune system Brain : a journal of neurology

    Key finding: However, the pathological processes linking traumatic brain injury and neurodegenerative disease remain poorly understood. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2013-01-01

    Mesenchymal stem cells enhance autophagy and increase β-amyloid clearance in Alzheimer disease models

    ✓ Peer-reviewed Brain tissue and pathology Autophagy

    Key finding: Using in vitro and in vivo AD models, the present study investigated whether mesenchymal stem cells (MSCs) could enhance autophagy and thus exert a neuroprotective effect through modulation of Aβ clearance In Aβ-treated neuronal cells, MSCs increased cellular viability and enhanced LC3-II expression compared with cells treated with Aβ only. +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2013-01-01

    Clinical symptoms and symptom signatures of Alzheimer's disease subgroups

    ✓ Peer-reviewed Tau biomarkers Journal of Alzheimer's disease : JAD

    Key finding: Over 99% of AD patients suffer from the sporadic form of the disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2013-01-01

    Marked increase of the astrocytic marker S100B in the cerebrospinal fluid of HIV-infected patients on LPV/r-monotherapy

    ✓ Peer-reviewed Tau biomarkers AIDS (London, England)

    Key finding: The Monotherapy Switzerland/Thailand study (MOST) trial compared monotherapy with ritonavir-boosted lopinavir with continued therapy. +3 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2013-01-01

    TREM2 R47H variant as a risk factor for early-onset Alzheimer's disease

    ✓ Peer-reviewed TREM2 and immune genetics Journal of Alzheimer's disease : JAD

    Key finding: In this study we examined the association between TREM2 exon 2 variants and early-onset AD in a sample of Caucasian subjects of French origin including 726 patients with age of onset ≤65 years and 783 controls. +2 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2013-01-01

    Brain microstructure reveals early abnormalities more than two years prior to clinical progression from mild cognitive impairment to Alzheimer's disease

    ✓ Peer-reviewed Mild cognitive impairment The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Significant group differences were mainly found in the volume and microstructure of the left hippocampus, while white matter group differences were also found in the body of the fornix, left fimbria, and superior longitudinal fasciculus (SLF). +1 more finding

    Full summary, score breakdown and related studies → Original source

  22. 2013-01-01

    Synthetic tau fibrils mediate transmission of neurofibrillary tangles in a transgenic mouse model of Alzheimer's-like tauopathy

    ✓ Peer-reviewed Lewy body dementia The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Although emerging evidence suggests that tau pathology may be transmitted, we demonstrate here that synthetic tau fibrils are sufficient to transmit tau inclusions in a mouse model.

    Full summary, score breakdown and related studies → Original source

  23. 2013-01-01

    The many faces of α-synuclein: from structure and toxicity to therapeutic target

    ✓ Peer-reviewed Lewy body dementia Nature reviews. Neuroscience

    Key finding: Disorders characterized by α-synuclein (α-syn) accumulation, Lewy body formation and parkinsonism (and in some cases dementia) are collectively known as Lewy body diseases. +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2013-01-01

    Apolipoprotein A-I: insights from redox proteomics for its role in neurodegeneration

    ✓ Peer-reviewed Down syndrome and Alzheimer's Proteomics. Clinical applications

    Key finding: Using proteomic techniques, apolipoprotein A-I (ApoA-I) has been found at decreased levels in subjects with a variety of neurodegenerative disorders including in the serum and cerebrospinal fluid (CSF) of Alzheimer disease (AD), Parkinson disease (PD), and Down syndrome (DS) with gout subjects. +4 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2013-01-01

    Automated assessment of cognitive health using smart home technologies

    ✓ Peer-reviewed Digital health tools Technology and health care : official journal of the European Society for Engineering and Medicine

    Key finding: The results suggest that it is possible to automatically quantify the task quality of smart home activities and perform limited assessment of the cognitive health of individual if smart home activities are properly chosen and learning algorithms are appropriately trained. +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →