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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 19,326–19,350 of 27,380 studies, newest first · page 774 of 1096.

July 2012 25

  1. 2012-07-25

    Focal atrophy on MRI and neuropathologic classification of dementia with Lewy bodies

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: Patients with high likelihood DLB typically have normal hippocampal volumes but have atrophy in the dorsal mesopontine GM nuclei.

    Full summary, score breakdown and related studies → Original source

  2. 2012-07-25

    Microstructural white matter changes in cognitively normal individuals at risk of amnestic MCI

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: Microstructural white matter changes are present in cognitively normal individuals in the pre-aMCI stage, and may serve as a potential imaging marker of early AD-related brain changes.

    Full summary, score breakdown and related studies → Original source

  3. 2012-07-25

    Trajectory of white matter hyperintensity burden preceding mild cognitive impairment

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: Acceleration in WMH burden, a common indicator of cerebrovascular disease in the elderly, is a pathologic change that emerges early in the presymptomatic phase leading to MCI. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2012-07-25

    Regional cerebral perfusion in patients with Alzheimer's disease and mild cognitive impairment: effect of APOE epsilon4 allele

    ✓ Peer-reviewed Genetics Neuroradiology

    Key finding: The objective of this study was to evaluate the effect of apolipoprotein E (APOE) epsilon 4 allele on regional cerebral perfusion (rCBF) changes using arterial spin labeling (ASL) magnetic resonance imaging (MRI) in subjects who are carriers or noncarriers of this risk factor for Alzheimer disease (AD). +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2012-07-24

    Postural stability and history of falls in cognitively able older adults: the Canton Ticino study

    ✓ Peer-reviewed Clinical safety Gait & posture

    Key finding: The mean position of the COP in the AP direction and the confidence ellipse area were associated with the fall-history in the EOFS, ECFS and EOCS conditions (P<0.05). +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2012-07-23

    Exendin-4 protected against cognitive dysfunction in hyperglycemic mice receiving an intrahippocampal lipopolysaccharide injection

    ✓ Peer-reviewed Drug development PloS one

    Key finding: These findings reveal that both hyperglycemia and intrahippocampal LPS injection induced cognitive dysfunction via activation of NF-κB-related inflammatory responses. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2012-07-22

    Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons

    ✓ Peer-reviewed Disease mechanisms Nature neuroscience

    Key finding: These results delineate an Aβ oligomer signal transduction pathway that requires PrP(C) and Fyn to alter synaptic function, with deleterious consequences in Alzheimer's disease.

    Full summary, score breakdown and related studies → Original source

  8. 2012-07-20

    Cerebrospinal fluid APOE levels: an endophenotype for genetic studies for Alzheimer's disease

    ✓ Peer-reviewed Genetics Human molecular genetics

    Key finding: The aim of this study was to test whether CSF or plasma APOE levels could be a useful endophenotype for AD and to identify genetic variants associated with APOE levels. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2012-07-20

    Acute injury in the peripheral nervous system triggers an alternative macrophage response

    ✓ Peer-reviewed TREM2 and immune genetics Journal of neuroinflammation

    Key finding: The activation of the immune system in neurodegeneration has detrimental as well as beneficial effects. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2012-07-18

    Serum ceramides increase the risk of Alzheimer disease: the Women's Health and Aging Study II

    ✓ Peer-reviewed Hippocampus size on brain scans Neurology

    Key finding: Twenty-seven (27.3%) of the 99 women developed incident dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2012-07-18

    Coevolution of white matter hyperintensities and cognition in the elderly

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: Aging-associated WMHs evolve significantly over a 4-year period. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2012-07-17

    Blood-Based Protein Biomarkers for Diagnosis of Alzheimer Disease

    ✓ Peer-reviewed Long-term cohort studies Archives of Neurology

    Key finding: A biomarker panel was identified that included markers significantly increased (cortisol, pancreatic polypeptide, insulinlike growth factor binding protein 2, β(2) microglobulin, vascular cell adhesion molecule 1, carcinoembryonic antigen, matrix metalloprotein 2, CD40, macrophage inflammatory protein 1α, superoxide dismutase, and homocysteine) and decreased (apolipoprotein E, epidermal growth factor receptor, hemoglobin, calcium, zinc, interleukin 17, and albumin) in AD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2012-07-17

    Insulin in the brain: there and back again

    ✓ Peer-reviewed Risk factors Pharmacology & therapeutics

    Key finding: Resistance to insulin action within the CNS, sometimes referred to as diabetes mellitus type III, is associated with peripheral insulin resistance, but it is possible that variable hormonal resistance syndromes exist so that resistance at one tissue bed may be independent of that at others. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2012-07-16

    The endoplasmic reticulum stress response in aging and age-related diseases

    ✓ Peer-reviewed Risk factors Frontiers in physiology

    Key finding: One mechanism to explain age associated declines in cellular functions and age-related diseases is a progressive failure of chaperoning systems. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2012-07-15

    Yogic meditation reverses NF-κB and IRF-related transcriptome dynamics in leukocytes of family dementia caregivers in a randomized controlled trial

    ✓ Peer-reviewed Caregiving Psychoneuroendocrinology

    Key finding: In response to KKM treatment, 68 genes were found to be differentially expressed (19 up-regulated, 49 down-regulated) after adjusting for potentially confounded differences in sex, illness burden, and BMI. +1 more finding

    Full summary, score breakdown and related studies → Original source

  16. 2012-07-13

    Geographical variation in dementia: systematic review with meta-analysis

    ✓ Peer-reviewed Disparities International journal of epidemiology

    Key finding: There is evidence of geographical variation in rates of dementia in affluent countries at a variety of geographical scales. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2012-07-11

    Amyloid imaging in Alzheimer's disease: comparison of florbetapir and Pittsburgh compound-B positron emission tomography

    ✓ Peer-reviewed Brain scans and imaging Journal of neurology, neurosurgery, and psychiatry

    Key finding: Both ligands displayed highly significant group discrimination and correlation of regional uptake. +1 more finding

    Full summary, score breakdown and related studies → Original source

  18. 2012-07-11

    Computerized cognitive training with older adults: a systematic review

    ✓ Peer-reviewed Cognitive tests and assessment PloS one

    Key finding: Studies were included if they met the following criteria: average sample age of at least 55 years at time of training; participants did not have Alzheimer's disease or mild cognitive impairment; and the study measured cognitive outcomes as a result of training. +1 more finding

    Full summary, score breakdown and related studies → Original source

  19. 2012-07-11

    Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease

    ✓ Peer-reviewed Biomarkers New England Journal of Medicine

    Key finding: Concentrations of amyloid-beta (Aβ)(42) in the CSF appeared to decline 25 years before expected symptom onset. +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2012-07-11

    Retinopathy and risk of dementia: the Rotterdam Study

    ✓ Peer-reviewed Long-term cohort studies Neurology

    Key finding: We investigated the associations between retinopathy and dementia and its subtypes Alzheimer disease (AD) and vascular dementia both cross-sectionally and prospectively in the Rotterdam Study, a large population-based cohort study. +3 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2012-07-11

    Amyloid-β assessed by florbetapir F 18 PET and 18-month cognitive decline: a multicenter study

    ✓ Peer-reviewed Cognitive tests and assessment Neurology

    Key finding: Florbetapir F 18 PET can image amyloid-β (Aβ) aggregates in the brains of living subjects. +3 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2012-07-11

    Vitamin D, effects on brain development, adult brain function and the links between low levels of vitamin D and neuropsychiatric disease

    ✓ Peer-reviewed Brain scans and imaging Frontiers in neuroendocrinology

    Key finding: Increasingly vitamin D deficiency is being associated with a number of psychiatric conditions. +1 more finding

    Full summary, score breakdown and related studies → Original source

  23. 2012-07-10

    Genetic architectures of psychiatric disorders: the emerging picture and its implications

    ✓ Peer-reviewed Prevention and risk Nature reviews. Genetics

    Key finding: Psychiatric disorders are among the most intractable enigmas in medicine. +4 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2012-07-10

    Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy

    ✓ Peer-reviewed Laboratory science Neurodegenerative Diseases

    Key finding: Acute injections of Aβ oligomers had no effect on p-tau epitopes but did result in elevation of phosphorylated/activated GSK3 (pGSK3). +4 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2012-07-10

    Late-stage Parkinson disease

    ✓ Peer-reviewed Brain tissue and pathology Nature reviews. Neurology

    Key finding: However, the presence and spectrum of, and disability caused by, nonmotor symptoms (NMS) are being increasingly recognized. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →