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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 19,451–19,475 of 27,380 studies, newest first · page 779 of 1096.

May 2012 25

  1. 2012-05-24

    Apolipoprotein E ε4 and age effects on florbetapir positron emission tomography in healthy aging and Alzheimer disease

    ✓ Peer-reviewed Brain scans and imaging Neurobiology of aging

    Key finding: Cerebral amyloid deposition is associated with APOE4 carrier status in older healthy control subjects and symptomatic AD patients, and increases with age in older cognitively normal individuals. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2012-05-24

    Nutritional treatment of aged individuals with Alzheimer disease living at home with their spouses: study protocol for a randomized controlled trial

    ✓ Peer-reviewed Treatments Trials

    Key finding: This study provides data on whether tailored nutritional care is beneficial to home-dwelling AD patients and their spouses. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2012-05-23

    Regional dynamics of amyloid-β deposition in healthy elderly, mild cognitive impairment and Alzheimer's disease: a voxelwise PiB-PET longitudinal study

    ✓ Peer-reviewed Mild cognitive impairment Brain : a journal of neurology

    Key finding: However, few longitudinal Pittsburgh compound B-positron emission tomography studies have tested this hypothesis, and with conflicting results. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2012-05-23

    Dementia incidence and mortality in middle-income countries, and associations with indicators of cognitive reserve: a 10/66 Dementia Research Group population-based cohort study

    ✓ Peer-reviewed Disparities Lancet (London, England)

    Key finding: 12,887 participants were interviewed at baseline. 11,718 were free of dementia, of whom 8137 (69%) were reinterviewed, contributing 34,718 person-years of follow-up. +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2012-05-22

    Preferences for end-of-life treatment: concordance between older adults with dementia or mild cognitive impairment and their spouses

    ✓ Peer-reviewed End-of-life care International psychogeriatrics

    Key finding: Our results show that regarding end-of-life preferences for patients, there is moderate agreement between patients and their spouses, but limited evidence for projection of spouses' preferences on patients (i.e. spouse making a prediction based on own wishes). +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2012-05-22

    Derivation and validation of updated QFracture algorithm to predict risk of osteoporotic fracture in primary care in the United Kingdom: prospective open cohort study

    ✓ Peer-reviewed Risk factors BMJ (Clinical research ed.)

    Key finding: We found significant independent associations with overall fracture risk in women for age, body mass index, ethnic origin, alcohol intake, smoking status, chronic obstructive pulmonary disease or asthma, any cancer, cardiovascular disease, dementia, diagnosis or treatment for epilepsy, history of falls, chronic liver disease, Parkinson's disease, rheumatoid arthritis or systemic lupus erythematosus, chronic renal disease, type 1 diabetes, type 2 diabetes, previous fracture, endocrine disorders, gastrointestinal malabsorption, any antidepressants, corticosteroids, unopposed hormone replacement therapy, and parental history of osteoporosis. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2012-05-22

    The problem with "problem behaviors": a systematic review of the association between individual patient behavioral and psychological symptoms and caregiver depression and burden within the dementia patient-caregiver dyad

    ✓ Peer-reviewed Caregiving International psychogeriatrics

    Key finding: The evidence is not conclusive as to whether some symptoms are more important than others. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2012-05-21

    Neuropsychological measures predict decline to Alzheimer's dementia from mild cognitive impairment

    ✓ Peer-reviewed Prevention trials Neuropsychology

    Key finding: At 20 months 12.3% of the MCI group progressed to dementia, 62.9% continued to meet MCI criteria, and 24.7% reverted to unimpaired levels of function. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2012-05-21

    Hypertension induces brain β-amyloid accumulation, cognitive impairment, and memory deterioration through activation of receptor for advanced glycation end products in brain vasculature

    ✓ Peer-reviewed Inflammation and the immune system Hypertension (Dallas, Tex. : 1979)

    Key finding: We developed a model of hypertension, obtained by transverse aortic constriction, leading to alterations typical of Alzheimer disease, such as amyloid plaques, neuroinflammation, blood-brain barrier dysfunction, and cognitive impairment, shown here for the first time. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2012-05-21

    Microglial activatory (immunoreceptor tyrosine-based activation motif)- and inhibitory (immunoreceptor tyrosine-based inhibition motif)-signaling receptors for recognition of the neuronal glycocalyx

    ✓ Peer-reviewed TREM2 and immune genetics Glia

    Key finding: To fulfill this task, microglia express a whole set of recognition receptors. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2012-05-19

    Evaluation and management of oropharyngeal dysphagia in different types of dementia: a systematic review

    ✓ Peer-reviewed Clinical safety Archives of gerontology and geriatrics

    Key finding: Prevalence of swallowing difficulties in patients with dementia ranged from 13 to 57%. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2012-05-18

    Inhibition of tau aggregation in a novel Caenorhabditis elegans model of tauopathy mitigates proteotoxicity

    ✓ Peer-reviewed Disease mechanisms Human molecular genetics

    Key finding: In addition, we observed that the axonal transport of mitochondria was perturbed in these animals.

    Full summary, score breakdown and related studies → Original source

  13. 2012-05-18

    Comparison of the quick mild cognitive impairment (Qmci) screen and the SMMSE in screening for mild cognitive impairment

    ✓ Peer-reviewed Cognitive tests and assessment Age and ageing

    Key finding: The AB Cognitive Screen (ABCS) 135, sensitive in differentiating MCI from dementia, was modified to improve sensitivity and specificity, producing the quick mild cognitive impairment (Qmci) screen. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2012-05-17

    The neurobiology of depression in later-life: clinical, neuropsychological, neuroimaging and pathophysiological features

    ✓ Peer-reviewed Brain tissue and pathology Progress in neurobiology

    Key finding: Like dementia, late-life depressive disorders are common and are linked to increased disability, high healthcare utilisation, cognitive decline and premature mortality. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2012-05-17

    Strikingly different clinicopathological phenotypes determined by progranulin-mutation dosage

    ✓ Peer-reviewed Lewy body dementia American journal of human genetics

    Key finding: Unexpectedly, we found these siblings to be homozygous for a c.813_816del (p.Thr272Serfs∗10) mutation in the progranulin gene (GRN, granulin precursor) in the latter peak. +2 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2012-05-16

    Apolipoprotein E controls cerebrovascular integrity via cyclophilin A

    ✓ Peer-reviewed Risk factors Nature

    Key finding: APOE4 is a major genetic risk factor for Alzheimer's disease and is associated with Down's syndrome dementia and poor neurological outcome after traumatic brain injury and haemorrhage. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2012-05-15

    Liraglutide protects against amyloid-β protein-induced impairment of spatial learning and memory in rats

    ✓ Peer-reviewed Drug development Neurobiology of aging

    Key finding: We found that (1) bilateral intrahippocampal injection of Aβ(25-35) resulted in a significant decline of spatial learning and memory of rats in water maze tests, together with a serious depression of in vivo hippocampal late-phase long-term potentiation (L-LTP) in CA1 region of rats; (2) pretreatment with liraglutide effectively and dose-dependently protected against the Aβ(25-35)-induced impairment of spatial memory and deficit of L-LTP; (3) liraglutide injection also activated cAMP signal pathway in the brain, with a nearly doubled increase in the cAMP contents compared with control. +1 more finding

    Full summary, score breakdown and related studies → Original source

  18. 2012-05-15

    Genome-wide association study of Alzheimer's disease

    ✓ Peer-reviewed Genetics Translational psychiatry

    Key finding: As expected, several markers in the APOE regions showed genome-wide significant associations in the Pittsburg sample. +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2012-05-15

    Olfactory dysfunction in Parkinson disease

    ✓ Peer-reviewed Getting a diagnosis Nature reviews. Neurology

    Key finding: These neuroanatomical findings, together with evidence for involvement of the autonomic nervous system in numerous PD-related symptoms, suggest that deficits in cholinergic, noradrenergic and serotonergic function may contribute to the olfactory loss.

    Full summary, score breakdown and related studies → Original source

  20. 2012-05-15

    Convergent functional genomics of schizophrenia: from comprehensive understanding to genetic risk prediction

    ✓ Peer-reviewed Genetics Molecular psychiatry

    Key finding: Overall, the data are consistent with a model of disrupted connectivity in schizophrenia, resulting from the effects of neurodevelopmental environmental stress on a background of genetic vulnerability. +2 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2012-05-11

    Disturbance of emotion processing in frontotemporal dementia: a synthesis of cognitive and neuroimaging findings

    ✓ Peer-reviewed Digital health tools Neuropsychology review

    Key finding: Accurate processing of emotional information is a critical component of appropriate social interactions and interpersonal relationships.

    Full summary, score breakdown and related studies → Original source

  22. 2012-05-11

    Cigarette smoking accelerated brain aging and induced pre-Alzheimer-like neuropathology in rats

    ✓ Peer-reviewed Risk genes beyond APOE PloS one

    Key finding: To date, little is known for how smoking can predispose our brains to dementia or cognitive impairment. +3 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2012-05-11

    A 1-year randomized controlled trial comparing mind body exercise (Tai Chi) with stretching and toning exercise on cognitive function in older Chinese adults at risk of cognitive decline

    ✓ Peer-reviewed Prevention and risk Journal of the American Medical Directors Association

    Key finding: Regular exercise, especially mind-body exercise with integrated cognitive and motor coordination, may help with preservation of global ability in elders at risk of cognitive decline; however, logistics to promote long-term practice and optimize adherence needs to be revisited. +2 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2012-05-10

    Sports concussions and aging: a neuroimaging investigation

    ✓ Peer-reviewed Hippocampus size on brain scans Cerebral cortex (New York, N.Y. : 1991)

    Key finding: Former athletes who sustained their last sports concussion >3 decades prior to testing were compared with those with no history of traumatic brain injury. +1 more finding

    Full summary, score breakdown and related studies → Original source

  25. 2012-05-10

    Executive function and activities of daily living in Alzheimer's disease: a correlational meta-analysis

    ✓ Peer-reviewed Clinical safety Dementia and geriatric cognitive disorders

    Key finding: The meta-analysis suggests a consistent moderate association between ADL and EF, supporting the growing evidence for a link between ADL and executive dysfunction in early dementia. +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →