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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 18,701–18,725 of 27,380 studies, newest first · page 749 of 1096.

May 2013 6

  1. 2013-05-01

    Prognosis of mild cognitive impairment in early Parkinson disease: the Norwegian ParkWest study

    ✓ Peer-reviewed Mild cognitive impairment JAMA neurology

    Key finding: Significantly more patients with MCI than without MCI at baseline (10 of 37 [27.0%] vs 1 of 145 [0.7%]; relative risk, 39.2 [95% CI, 5.2-296.5]; P Conclusions and relevance Mild cognitive impairment at PD diagnosis predicts a highly increased risk for early dementia.

    Full summary, score breakdown and related studies → Original source

  2. 2013-05-01

    The Mental Activity and eXercise (MAX) trial: a randomized controlled trial to enhance cognitive function in older adults

    ✓ Peer-reviewed Disparities JAMA internal medicine

    Key finding: Participants had a mean age of 73.4 years; 62.7% were women, and 34.9% were Hispanic or nonwhite. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2013-05-01

    Mechanisms of sporadic cerebral small vessel disease: insights from neuroimaging

    ✓ Peer-reviewed Caregiving The Lancet. Neurology

    Key finding: Although the pathological processes leading to the arteriolar disease are associated with vascular risk factors and are believed to result from an intrinsic cerebral arteriolar occlusive disease, little is known about how these processes result in brain disease, how SVD lesions contribute to neurological or cognitive symptoms, and the association with risk factors.

    Full summary, score breakdown and related studies → Original source

  4. 2013-05-01

    Late-life depression and risk of vascular dementia and Alzheimer's disease: systematic review and meta-analysis of community-based cohort studies

    ✓ Peer-reviewed Prevention and risk The British journal of psychiatry : the journal of mental science

    Key finding: The present results suggest that it will be valuable to design clinical trials to investigate the effect of late-life depression prevention on risk of dementia, in particular vascular dementia and Alzheimer's disease. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2013-05-01

    Effects of the Finnish Alzheimer disease exercise trial (FINALEX): a randomized controlled trial

    ✓ Peer-reviewed Treatments JAMA internal medicine

    Key finding: An intensive and long-term exercise program had beneficial effects on the physical functioning of patients with AD without increasing the total costs of health and social services or causing any significant adverse effects. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2013-05-01

    Neuropathologic basis of age-associated brain atrophy

    ✓ Peer-reviewed Genetics JAMA neurology

    Key finding: Ventricular volume trajectory is more sensitive than total brain and hippocampal volume trajectories as a marker of accruing Alzheimer disease and vascular pathology in elderly individuals. +3 more findings

    Full summary, score breakdown and related studies → Original source

April 2013 19

  1. 2013-04-30

    Maternal choline supplementation improves spatial learning and adult hippocampal neurogenesis in the Ts65Dn mouse model of Down syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's Neurobiology of disease

    Key finding: Ts65Dn offspring of choline-supplemented dams performed significantly better than unsupplemented Ts65Dn mice. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2013-04-30

    Factors associated with weight loss, low BMI, and malnutrition among nursing home patients: a systematic review of the literature

    ✓ Peer-reviewed Clinical safety Journal of the American Medical Directors Association

    Key finding: Potentially modifiable factors consistently associated with increased likelihood of weight loss, low BMI, or poor nutrition included depression, impaired function, and poor oral intake. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2013-04-30

    Rapid accumulation of endogenous tau oligomers in a rat model of traumatic brain injury: possible link between traumatic brain injury and sporadic tauopathies

    ✓ Peer-reviewed Disease mechanisms The Journal of biological chemistry

    Key finding: These findings suggest that diagnostic tools and therapeutics that target only toxic forms of Tau may provide earlier detection and safe, more effective treatments for tauopathies associated with repetitive neurotrauma.

    Full summary, score breakdown and related studies → Original source

  4. 2013-04-30

    Arterial spin labeled MRI in prodromal Alzheimer's disease: A multi-site study

    ✓ Peer-reviewed Long-term cohort studies NeuroImage. Clinical

    Key finding: Measures of CBF, in a predetermined set of regions (meta-ROI), and hippocampal volume were compared between CN (n = 47), patients with early and late Mild Cognitive Impairment [EMCI (n = 32), LMCI (n = 35)], and AD (n = 15). +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2013-04-30

    A blood-based predictor for neocortical Aβ burden in Alzheimer's disease: results from the AIBL study

    ✓ Peer-reviewed Digital health tools Molecular psychiatry

    Key finding: Five analytes showed significant difference between subjects with high compared to low NAB. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2013-04-29

    Adhesion molecule L1 binds to amyloid beta and reduces Alzheimer's disease pathology in mice

    ✓ Peer-reviewed Biomarkers Neurobiology of disease

    Key finding: In an effort to contribute to the potential of molecular approaches to reduce degenerative processes we have tested the possibility that the neural adhesion molecule L1 ameliorates some characteristic cellular and molecular parameters associated with the disease in a mouse model of AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2013-04-29

    Neural predictors of individual differences in response to math tutoring in primary-grade school children

    ✓ Peer-reviewed Hippocampus size on brain scans Proceedings of the National Academy of Sciences of the United States of America

    Key finding: A significant shift in arithmetic problem-solving strategies from counting to fact retrieval was observed with tutoring. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2013-04-29

    Improving memory in Parkinson's disease: a healthy brain ageing cognitive training program

    ✓ Peer-reviewed Prevention trials Movement disorders : official journal of the Movement Disorder Society

    Key finding: This study aimed to evaluate the efficacy of a multifactorial 'healthy brain ageing cognitive training program' for Parkinson's disease. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2013-04-29

    TARDBP and FUS mutations associated with amyotrophic lateral sclerosis: summary and update

    ✓ Peer-reviewed Brain tissue and pathology Human mutation

    Key finding: Interestingly, TDP-43 positive inclusion bodies were first discovered in ubiquitin-positive, tau-negative ALS and frontotemporal dementia (FTD) inclusion bodies, and subsequently observed in the majority of neurodegenerative disorders. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2013-04-29

    Targeting norepinephrine in mild cognitive impairment and Alzheimer's disease

    ✓ Peer-reviewed Mild cognitive impairment Alzheimer's research & therapy

    Key finding: Advances in AD biomarker research have demonstrated changes in amyloid-beta (Aβ), brain metabolism and other pathophysiologies prior to the onset of memory loss, with some markers possibly changing one or two decades earlier. +2 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2013-04-27

    The impact of Medicare prescription drug coverage on the use of antidementia drugs

    ✓ Peer-reviewed Health systems and care delivery BMC Geriatrics

    Key finding: The No coverage group had a 38% increase in the odds ratio of any use of antidementia medications (P = 0.0008) post-Part D relative to the No cap group. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2013-04-26

    Sexuality in nursing homes: practice and policy

    ✓ Peer-reviewed Health systems and care delivery Journal of gerontological nursing

    Key finding: Many responses indicated that sexual expression of residents was considered non-normative. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2013-04-26

    Anti-amyloid β autoantibodies in cerebral amyloid angiopathy-related inflammation: implications for amyloid-modifying therapies

    ✓ Peer-reviewed Treatments Annals of neurology

    Key finding: Our data support the hypothesis that the pathogenesis of CAA-ri may be mediated by a selective autoimmune reaction against cerebrovascular Aβ, directly related to autoantibody concentration and soluble Aβ.

    Full summary, score breakdown and related studies → Original source

  14. 2013-04-26

    Calcium-sensing receptor antagonist (calcilytic) NPS 2143 specifically blocks the increased secretion of endogenous Aβ42 prompted by exogenous fibrillary or soluble Aβ25-35 in human cortical astrocytes and neurons-therapeutic relevance to Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Biochimica et biophysica acta

    Key finding: Previously we showed that fibrillar (f)Aβ25-35, an Aβ42 proxy, evokes a surplus endogenous Aβ42 production/accumulation in cortical adult human astrocytes. +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2013-04-26

    Diabetes mellitus and risk of dementia: A meta-analysis of prospective observational studies

    ✓ Peer-reviewed How common it is Journal of diabetes investigation

    Key finding: The results showed a 73% increased risk of ATD, 56% increase of AD and 127% increase of VaD in diabetes patients. +2 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2013-04-26

    Heart disease as a risk factor for dementia

    ✓ Peer-reviewed Prevention and risk Clinical epidemiology

    Key finding: As life expectancy lengthens, dementia is becoming a significant human condition in terms of its prevalence and cost to society worldwide.

    Full summary, score breakdown and related studies → Original source

  17. 2013-04-25

    ApoE influences amyloid-β (Aβ) clearance despite minimal apoE/Aβ association in physiological conditions

    ✓ Peer-reviewed Tau biomarkers Proceedings of the National Academy of Sciences of the United States of America

    Key finding: We find that a significant portion of apoE and sAβ compete for the low-density lipoprotein receptor-related protein 1 (LRP1)-dependent cellular uptake pathway in astrocytes, providing a mechanism to account for apoE's regulation of sAβ metabolism despite minimal evidence of direct interactions in extracellular fluids. +1 more finding

    Full summary, score breakdown and related studies → Original source

  18. 2013-04-25

    Alzheimer’s Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta

    ✓ Peer-reviewed Risk genes beyond APOE Neuron

    Key finding: Increased expression of CD33 in microglial cells in AD brain. +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2013-04-24

    The coming crisis: obtaining care for the growing burden of neurodegenerative conditions

    ✓ Peer-reviewed Costs and economics Neurology

    Key finding: However, many of these patients and their families currently do not receive neurologic care. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →