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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 20,576–20,600 of 27,380 studies, newest first · page 824 of 1096.

September 2010 25

  1. 2010-09-07

    Treatment of cardiovascular risk factors to prevent cognitive decline and dementia: a systematic review

    ✓ Peer-reviewed Treatments Vascular health and risk management

    Key finding: The evidence of a preventive treatment effect aimed at vascular risk factors on cognitive decline and dementia in later life is scarce and mostly based on secondary outcome parameters. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2010-09-03

    Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio

    ✓ Peer-reviewed Treatments The EMBO journal

    Key finding: We show here that small alterations in the Aβ(42):Aβ(40) ratio dramatically affect the biophysical and biological properties of the Aβ mixtures reflected in their aggregation kinetics, the morphology of the resulting amyloid fibrils and synaptic function tested in vitro and in vivo. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2010-09-03

    Advance care planning for patients with ALS: feasibility of an interactive computer program

    ✓ Peer-reviewed End-of-life care Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases

    Key finding: Seventeen individuals completed the pre-intervention questionnaires and decision aid; 16/17 (94%) completed the post-intervention measures, and none reported any burden from the intervention. 'Overall satisfaction' with the decision aid was very high (mean = 8.5 ± 0.27: 1 = not at all satisfied, 10 = extremely satisfied), as was 'perceived accuracy' of the computer generated advance directive in reflecting patients' wishes (mean = 8.6 ± 0.27: 1 = not at all accurate, 10 = extremely accurate). +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2010-09-02

    Inhibition of GSK-3 ameliorates Abeta pathology in an adult-onset Drosophila model of Alzheimer's disease

    ✓ Peer-reviewed Drug development PLoS genetics

    Key finding: Expression of Abeta42 in adult neurons increased GSK-3 activity, and inhibition of GSK-3 (either genetically or pharmacologically by lithium treatment) rescued Abeta42 toxicity. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2010-09-01

    Abeta oligomers cause localized Ca(2+) elevation, missorting of endogenous Tau into dendrites, Tau phosphorylation, and destruction of microtubules and spines

    ✓ Peer-reviewed Disease mechanisms The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: These local effects occur without global changes in Tau, tubulin, or kinase levels. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2010-09-01

    Modulation of gamma-secretase reduces beta-amyloid deposition in a transgenic mouse model of Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms Neuron

    Key finding: Moreover, oral administration (once daily) of another potent GSM to Tg 2576 transgenic AD mice displayed dose-responsive lowering of plasma and brain Abeta(42); chronic daily administration led to significant reductions in both diffuse and neuritic plaques. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2010-09-01

    Cachexia as a major underestimated and unmet medical need: facts and numbers

    ✓ Peer-reviewed Prevention and risk Journal of cachexia, sarcopenia and muscle

    Key finding: In industrialized countries (North America, Europe, Japan), the overall prevalence of cachexia (due to any disease) is growing and currently about 1%, i.e., about nine million patients. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2010-09-01

    Diagnosis of Alzheimer's disease from EEG signals: where are we standing?

    ✓ Peer-reviewed Brain scans and imaging Current Alzheimer research

    Key finding: Before one can analyze EEG, it is necessary to remove artifacts due to for example head and eye movement or interference from electronic equipment. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2010-09-01

    Exercise and Alzheimer's disease biomarkers in cognitively normal older adults

    ✓ Peer-reviewed Brain scans and imaging Annals of neurology

    Key finding: These results are supportive of an association between exercise engagement and AD biomarkers in cognitively normal older adults. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2010-09-01

    Progression of brain atrophy and cognitive decline in diabetes mellitus: a 3-year follow-up

    ✓ Peer-reviewed Vascular contributions Neurology

    Key finding: Our data show that elderly patients with DM without dementia have accelerated progression of brain atrophy with significant consequences in cognition compared to subjects without DM. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2010-09-01

    Antiinflammatory activity of melatonin in central nervous system

    ✓ Peer-reviewed Vascular contributions Current neuropharmacology

    Key finding: Its secretion from the pineal gland has been classically associated with circadian and circanual rhythm regulation. +2 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2010-09-01

    Structural changes in the hippocampus in major depressive disorder: contributions of disease and treatment

    ✓ Peer-reviewed Hippocampus size on brain scans Journal of psychiatry & neuroscience : JPN

    Key finding: Our results suggest that decreased hippocampal tail and hippocampal head volumes could be trait changes, whereas hippocampal body changes may be dependent on treatment. +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2010-09-01

    Hippocampal atrophy patterns in mild cognitive impairment and Alzheimer's disease

    ✓ Peer-reviewed Hippocampus size on brain scans Human brain mapping

    Key finding: The patterns of subfield atrophy in AD and MCI were consistent with patterns of neuronal cell loss/reduced synaptic density described by histopathology. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2010-09-01

    Dementia, dignity and quality of life: nursing practice and its dilemmas

    ✓ Peer-reviewed End-of-life care International journal of older people nursing

    Key finding: Each vignette promoted discussion of differences of perspectives about the ways to enhance the dignity of people with dementia in hospital, care home and community settings.

    Full summary, score breakdown and related studies → Original source

  15. 2010-09-01

    The blood-brain barrier: geriatric relevance of a critical brain-body interface

    ✓ Peer-reviewed Clinical safety Journal of the American Geriatrics Society

    Key finding: Aging, systemic diseases, and ischemic injury can disrupt these processes, resulting in a decline in overall BBB function and integrity.

    Full summary, score breakdown and related studies → Original source

  16. 2010-09-01

    Clinical spectrum of Kufor-Rakeb syndrome in the Chilean kindred with ATP13A2 mutations

    ✓ Peer-reviewed Clinical safety Movement disorders : official journal of the Movement Disorder Society

    Key finding: Examination revealed bradykinesia, subtle postural/action tremor, cogwheel rigidity, spasticity, upward gaze palsy, smooth pursuit with saccadic intrusions, and dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2010-09-01

    Prevalence and risk factors for development of delirium in burn intensive care unit patients

    ✓ Peer-reviewed Clinical safety Journal of burn care & research : official publication of the American Burn Association

    Key finding: Delirium affects 60 to 80% of ventilated patients and is associated with worse clinical outcomes including death. +2 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2010-09-01

    Physical activity and mild cognitive impairment and Alzheimer's disease

    ✓ Peer-reviewed Prevention trials Current neurology and neuroscience reports

    Key finding: In the past decade, researchers and clinicians have begun to focus their attention on whether physical activity also can improve health outcomes of older adults who experience mild cognitive impairment (MCI) or dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2010-09-01

    Biomarkers for early detection of Alzheimer disease

    ✓ Peer-reviewed Tau biomarkers The Journal of the American Osteopathic Association

    Key finding: Multidisciplinary clinical diagnosis of Alzheimer disease is time consuming and expensive and relies on experts who are rarely available outside of specialty clinics. +3 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2010-09-01

    Requiring an amyloid-beta1-42 biomarker for prodromal Alzheimer's disease or mild cognitive impairment does not lead to more efficient clinical trials

    ✓ Peer-reviewed Tau biomarkers Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Low cerebrospinal fluid (CSF) amyloid-beta(1-42) concentration and high total-tau/Abeta(1-42) ratio have been recommended to support the diagnosis of prodromal Alzheimer's disease (AD) in patients with amnestic mild cognitive impairment (aMCI) and also to select patients for clinical trials (Shaw et al, Ann Neurol 2009;65:403-13; Dubois et al, Lancet Neurol 2007;6:734-46). +3 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2010-09-01

    Effect of brain-derived neurotrophic factor Val66Met polymorphism and serum levels on the progression of mild cognitive impairment

    ✓ Peer-reviewed Mild cognitive impairment The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry

    Key finding: The presence of Met-BDNF allele, particularly in association with APOE*E4, may predict a worse cognitive outcome in patients with MCI. +1 more finding

    Full summary, score breakdown and related studies → Original source

  22. 2010-09-01

    Plasma ceramides are altered in mild cognitive impairment and predict cognitive decline and hippocampal volume loss

    ✓ Peer-reviewed Mild cognitive impairment Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: These plasma ceramides may be early indicators of AD progression. +2 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2010-09-01

    Clinical aspects of melatonin intervention in Alzheimer's disease progression

    ✓ Peer-reviewed Mild cognitive impairment Current neuropharmacology

    Key finding: Search terms were "Alzheimer" and "melatonin". +4 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2010-09-01

    TDP-43 proteinopathy and motor neuron disease in chronic traumatic encephalopathy

    ✓ Peer-reviewed Lewy body dementia Journal of neuropathology and experimental neurology

    Key finding: Epidemiological evidence suggests that the incidence of amyotrophic lateral sclerosis is increased in association with head injury. +4 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2010-09-01

    Acetylation of tau inhibits its degradation and contributes to tauopathy

    ✓ Peer-reviewed Lewy body dementia Neuron

    Key finding: We found that tau is acetylated and that tau acetylation prevents degradation of phosphorylated tau (p-tau). +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →