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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 19,201–19,225 of 27,380 studies, newest first · page 769 of 1096.

September 2012 25

  1. 2012-09-26

    Injury markers predict time to dementia in subjects with MCI and amyloid pathology

    ✓ Peer-reviewed Genetics Neurology

    Key finding: In subjects with MCI and evidence of amyloid pathology, the injury markers CSF t-tau and p-tau and hippocampal atrophy can predict further cognitive decline.

    Full summary, score breakdown and related studies → Original source

  2. 2012-09-25

    Toward a predictive model of Alzheimer's disease progression using capillary electrophoresis-mass spectrometry metabolomics

    ✓ Peer-reviewed Mild cognitive impairment Analytical chemistry

    Key finding: Our results suggest that CE-MS metabolomics of CSF samples can be a useful tool to predict AD progression.

    Full summary, score breakdown and related studies → Original source

  3. 2012-09-25

    The Beijing version of the Montreal Cognitive Assessment as a brief screening tool for mild cognitive impairment: a community-based study

    ✓ Peer-reviewed Getting a diagnosis BMC psychiatry

    Key finding: In general, the MoCA-BJ is an acceptable tool for MCI screening in both urban and rural regions of Beijing. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2012-09-24

    Abnormal network connectivity in frontotemporal dementia: evidence for prefrontal isolation

    ✓ Peer-reviewed Digital health tools Cortex; a journal devoted to the study of the nervous system and behavior

    Key finding: The present findings support a theory of FTD as a disorder of frontolimbic disconnection leading to unconstrained prefrontal connectivity. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2012-09-24

    Cross-sectional and longitudinal association of body mass index and brain volume

    ✓ Peer-reviewed Hippocampus size on brain scans Human brain mapping

    Key finding: We found that associations of BMI and brain volume were not significantly different in former lead workers when compared with community controls. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2012-09-21

    The diabetes drug liraglutide ameliorates aberrant insulin receptor localisation and signalling in parallel with decreasing both amyloid-β plaque and glial pathology in a mouse model of Alzheimer's disease

    ✓ Peer-reviewed Drug development Neuromolecular medicine

    Key finding: In the present study, we show that distinctive alterations in the localisation and distribution of the IR and increased levels of insulin receptor substrate (IRS)-1 phosphorylated at serine 616 (IRS-1 pS(616)), a key marker of insulin resistance, are associated with amyloid-β plaque pathology in the frontal cortex of a mouse model of AD, APPSWE/PS1dE9. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2012-09-20

    The neuroprotective effects of GLP-1: possible treatments for cognitive deficits in individuals with mood disorders

    ✓ Peer-reviewed Drug development Behavioural brain research

    Key finding: Mood disorders (e.g. bipolar disorder (BD), major depressive disorder (MDD)) are associated with similar alterations in brain structure and function, as well as a range of cognitive deficits (e.g. memory, learning, executive function). +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2012-09-20

    The prevalence of dementia in rural Tanzania: a cross-sectional community-based study

    ✓ Peer-reviewed Disparities International journal of geriatric psychiatry

    Key finding: The prevalence of dementia in this rural Tanzanian population is similar to that reported in high-income countries. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2012-09-20

    Dimebon alters hippocampal amyloid pathology in 3xTg-AD mice

    ✓ Peer-reviewed Biomarkers International journal of physiology, pathophysiology and pharmacology

    Key finding: A double blind, placebo-controlled phase II study revealed that the antihistamine, Dimebon® (dimebolin, latrepirdine) improved cognition in Alzheimer disease (AD) patients compared to placebo controls. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2012-09-19

    Guiding Principles for the Care of Older Adults with Multimorbidity: An Approach for Clinicians

    ✓ Peer-reviewed Health systems and care delivery Journal of the American Geriatrics Society

    Key finding: The heterogeneous patterns and severity of conditions produce distinctive cumulative effects for each individual.5 Multimorbidity is associated with many adverse consequences, including death, disability, institutionalization, greater use of healthcare resources, poorer quality of life, and higher rates of adverse effects of treatment or interventions.1 Comprehensive strategies for healthcare delivery that are not disease specific, as well as interventions that target geriatric syndromes common in older adults with multimorbidity, show promise for this population,5-9 although the best approaches to decision-making and clinical management of older adults with multimorbidity remain unclear. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2012-09-19

    Novel risk markers and long-term outcomes of delirium: the successful aging after elective surgery (SAGES) study design and methods

    ✓ Peer-reviewed Prevention and risk Journal of the American Medical Directors Association

    Key finding: Ultimately, we hope this project will provide the groundwork for future development of prevention and treatment strategies for delirium, designed to minimize the long term negative impact of delirium in older adults.

    Full summary, score breakdown and related studies → Original source

  12. 2012-09-18

    Engineering of blended nanoparticle platform for delivery of mitochondria-acting therapeutics

    ✓ Peer-reviewed Disease mechanisms Proceedings of the National Academy of Sciences

    Key finding: The versatility of this platform was demonstrated by studying various mitochondria-acting therapeutics for different applications, including the mitochondria-targeting chemotherapeutics lonidamine and α-tocopheryl succinate for cancer, the mitochondrial antioxidant curcumin for Alzheimer's disease, and the mitochondrial uncoupler 2,4-dinitrophenol for obesity. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2012-09-18

    Neurotoxic potential of iron oxide nanoparticles in the rat brain striatum and hippocampus

    ✓ Peer-reviewed Risk factors Neurotoxicology

    Key finding: The striatum and hippocampus are important structures in the brain and are associated with the development of Parkinson's and Alzheimer's diseases. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2012-09-18

    Pinocembrin protects against β-amyloid-induced toxicity in neurons through inhibiting receptor for advanced glycation end products (RAGE)-independent signaling pathways and regulating mitochondrion-mediated apoptosis

    ✓ Peer-reviewed Disease mechanisms BMC medicine

    Key finding: Interaction between Aβ and the receptor for advanced glycation end products (RAGE) has been implicated in neuronal degeneration associated with this disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2012-09-17

    Anthocyanin-enriched bilberry and blackcurrant extracts modulate amyloid precursor protein processing and alleviate behavioral abnormalities in the APP/PS1 mouse model of Alzheimer's disease

    ✓ Peer-reviewed Biomarkers The Journal of nutritional biochemistry

    Key finding: A growing body of epidemiological evidence suggests that fruit and vegetable juices containing various phenolic compounds can reduce the risk of Alzheimer's disease (AD). +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2012-09-17

    Alzheimer disease and platelets: how's that relevant

    ✓ Peer-reviewed Risk genes beyond APOE Immunity & ageing : I & A

    Key finding: At the microscopic level distinctive features of AD are neurons and synapses degeneration, together with extensive amounts of senile plaques and neurofibrillars tangles. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2012-09-17

    β-Site amyloid precursor protein (APP)-cleaving enzyme 1 (BACE1)-deficient mice exhibit a close homolog of L1 (CHL1) loss-of-function phenotype involving axon guidance defects

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: However, little is known about the functions of BACE1. +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2012-09-17

    Motoric cognitive risk syndrome and the risk of dementia

    ✓ Peer-reviewed How common it is The journals of gerontology. Series A, Biological sciences and medical sciences

    Key finding: A motor-based MCR syndrome provides a clinical approach to identify individuals at high risk for dementia, especially vascular dementia, to target for further investigations and who may benefit from preventive interventions. +2 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2012-09-14

    Disrupted topological organization in white matter structural networks in amnestic mild cognitive impairment: relationship to subtype

    ✓ Peer-reviewed Brain scans and imaging Radiology

    Key finding: Moreover, cognitive correlations with topological network properties suggest their potential use as markers to assess the risk of Alzheimer disease.

    Full summary, score breakdown and related studies → Original source

  20. 2012-09-13

    Exercise therapy, cardiorespiratory fitness and their effect on brain volumes: a randomised controlled trial in patients with schizophrenia and healthy controls

    ✓ Peer-reviewed Hippocampus size on brain scans European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology

    Key finding: Significantly smaller baseline cerebral (grey) matter, and larger third ventricle volumes, and thinner cortex in most areas of the brain were found in patients versus controls. +1 more finding

    Full summary, score breakdown and related studies → Original source

  21. 2012-09-13

    Reliability of six physical performance tests in older people with dementia

    ✓ Peer-reviewed Cognitive tests and assessment Physical therapy

    Key finding: Physical performance tests are important for assessing the effect of physical activity interventions in older people with dementia, but their psychometric properties have not been systematically established within this specific population. +3 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2012-09-12

    Astrocyte Senescence as a Component of Alzheimer’s Disease

    ✓ Peer-reviewed Disease mechanisms PLoS ONE

    Key finding: Compared with fetal tissue samples (n = 4), a significant increase in p16(INK4a)-positive astrocytes was observed in subjects aged 35 to 50 years (n = 6; P = 0.02) and 78 to 90 years (n = 11; P<10(-6)). +3 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2012-09-12

    Target-based selection of flavonoids for neurodegenerative disorders

    ✓ Peer-reviewed Risk factors Trends in pharmacological sciences

    Key finding: Preclinical models suggest that flavonoids reduce hearing loss resulting from treatment with the chemotherapeutic drug cisplatin by opposing the excessive production of ROS and proinflammatory mediators implicated in PD, stroke, and AD.

    Full summary, score breakdown and related studies → Original source

  24. 2012-09-12

    Cholinesterase inhibitors for mild cognitive impairment

    ✓ Peer-reviewed Mild cognitive impairment The Cochrane database of systematic reviews

    Key finding: Main results Nine studies (from eight published reports) of 5149 individuals with mild cognitive impairment (however defined) were included in the review. +4 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2012-09-12

    Neuropathologically defined subtypes of Alzheimer's disease differ significantly from neurofibrillary tangle-predominant dementia

    ✓ Peer-reviewed Digital health tools Acta neuropathologica

    Key finding: On the other hand, cortical β-amyloid burden did not significantly differ between AD subtypes. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →