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What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 19,126–19,150 of 27,380 studies, newest first · page 766 of 1096.

November 2012 2

  1. 2012-11-01

    Safety and tolerability of the γ-secretase inhibitor avagacestat in a phase 2 study of mild to moderate Alzheimer disease

    ✓ Peer-reviewed Genetics Archives of neurology

    Key finding: Avagacestat dosed at 25 and 50 mg daily was relatively well tolerated and had low discontinuation rates. +1 more finding

  2. 2012-11-01

    Accuracy of a panel of 5 cerebrospinal fluid biomarkers in the differential diagnosis of patients with dementia and/or parkinsonian disorders

    ✓ Peer-reviewed Biomarkers Archives of neurology

    Key finding: Ascertainment of the -synuclein level in CSF somewhat improves the differential diagnosis of AD vs DLB and PDD when combined with established AD biomarkers. +2 more findings

October 2012 23

  1. 2012-10-30

    Excitotoxicity: bridge to various triggers in neurodegenerative disorders

    ✓ Peer-reviewed Risk factors European journal of pharmacology

    Key finding: Such an aberration, serves as a common pool or bridge between abnormal triggers and deleterious signaling processes with which central neurons cannot cope up, leading to death. +4 more findings

  2. 2012-10-30

    Statistical analysis of longitudinal neuroimage data with Linear Mixed Effects models

    ✓ Peer-reviewed Hippocampus size on brain scans NeuroImage

    Key finding: Our results suggest that the LME approach offers superior statistical power in detecting longitudinal group differences.

  3. 2012-10-30

    Influence of hospice on nursing home residents with advanced dementia who received Medicare-skilled nursing facility care near the end of life

    ✓ Peer-reviewed End-of-life care Journal of the American Geriatrics Society

    Key finding: Residents dying with advanced dementia who received SNF care in the last 90 days of life had fewer aggressive treatments and lower odds of hospital death if they also received hospice care at any point during that time. +2 more findings

  4. 2012-10-30

    Gait and cognition: a complementary approach to understanding brain function and the risk of falling

    ✓ Peer-reviewed Clinical safety Journal of the American Geriatrics Society

    Key finding: Quantifiable alterations in gait in older adults are associated with falls, dementia, and disability. +1 more finding

  5. 2012-10-30

    Psychosocial factors that shape patient and carer experiences of dementia diagnosis and treatment: a systematic review of qualitative studies

    ✓ Peer-reviewed Caregiving PLoS medicine

    Key finding: There is an extensive body of qualitative literature on the experiences of community-dwelling individuals with dementia on receiving and adapting to a diagnosis of dementia.

  6. 2012-10-29

    Oral curcumin for Alzheimer's disease: tolerability and efficacy in a 24-week randomized, double blind, placebo-controlled study

    ✓ Peer-reviewed Biomarkers Alzheimer's research & therapy

    Key finding: Mean age of completers (n = 30) was 73.5 years and mean Mini-Mental Status Examination (MMSE) score was 22.5. +2 more findings

  7. 2012-10-27

    Mild cognitive impairment in a community sample: the Sydney Memory and Ageing Study

    ✓ Peer-reviewed Mild cognitive impairment Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Incidence rates for MCI are higher than previously reported, particularly in men and for single-domain MCI; rates for amnestic and nonamnestic MCI were comparable. +2 more findings

  8. 2012-10-26

    The incretin analogue D-Ala2GIP reduces plaque load, astrogliosis and oxidative stress in an APP/PS1 mouse model of Alzheimer's disease

    ✓ Peer-reviewed Drug development Neuroscience

    Key finding: The results demonstrate that D-Ala(2)GIP has neuroprotective properties on key markers found in Alzheimer's disease.

  9. 2012-10-26

    Extracellular Tau levels are influenced by variability in Tau that is associated with tauopathies

    ✓ Peer-reviewed Tau biomarkers The Journal of biological chemistry

    Key finding: These diseases may occur by sporadic mechanisms in which genetic variants represent risk factors for disease, as is the case in Alzheimer disease (AD). +3 more findings

  10. 2012-10-25

    Diabetes in Older Adults: A Consensus Report

    ✓ Peer-reviewed Brain scans and imaging Journal of the American Geriatrics Society

    Key finding: More than 25% of the U.S. population aged ≥ 65 years has diabetes mellitus (hereafter referred to as diabetes),1 and the aging of the overall population is a significant driver of the diabetes epidemic. +4 more findings

  11. 2012-10-25

    STAR: ultrafast universal RNA-seq aligner

    ✓ Peer-reviewed Laboratory science Bioinformatics

    STAR outperforms other aligners by a factor of >50 in mapping speed, aligning to the human genome 550 million 2 × 76 bp paired-end reads per hour on a modest 12-core server, while at the same time improving alignment sensitivity and precision.

  12. 2012-10-24

    Functional network connectivity in the behavioral variant of frontotemporal dementia

    ✓ Peer-reviewed Brain scans and imaging Cortex; a journal devoted to the study of the nervous system and behavior

    Key finding: A decreased dorsal salience network (DSN) connectivity, mainly involving the anterior cingulum, was observed in bvFTD versus controls and pAD. +4 more findings

  13. 2012-10-24

    Seven sirtuins for seven deadly diseases of aging

    ✓ Peer-reviewed Caregiving Free radical biology & medicine

    Key finding: Since sirtuins are crucial to pathways that counter the decline in health that accompanies aging, pharmacological agents that boost sirtuin activity have clinical potential in treatment of diabetes, cardiovascular disease, dementia, osteoporosis, arthritis, and other conditions. +4 more findings

  14. 2012-10-24

    A higher adherence to a Mediterranean-style diet is inversely associated with the development of frailty in community-dwelling elderly men and women

    ✓ Peer-reviewed Prevention and risk The Journal of nutrition

    Key finding: Adherence to a Mediterranean-style diet is associated with a lower risk for mortality, cognitive decline, and dementia. +3 more findings

  15. 2012-10-24
  16. 2012-10-24

    Effects of APOE on brain white matter microstructure in healthy adults

    ✓ Peer-reviewed Genetics Neurology

    Key finding: APOE affects microstructural properties of the brain WM from early adulthood, but the specific allelic effects do not directly reflect the associated risk of developing Alzheimer disease. +3 more findings

  17. 2012-10-23

    Cerebral blood flow in Alzheimer's disease

    ✓ Peer-reviewed Hippocampus size on brain scans Vascular health and risk management

    Key finding: These results indicate an association between brain hypoperfusion and the dementia of AD. +4 more findings

  18. 2012-10-23

    The experience of providing end-of-life care to a relative with advanced dementia: an integrative literature review

    ✓ Peer-reviewed End-of-life care Palliative & supportive care

    Key finding: This article presents what is known and highlights the gaps in the literature relevant to the experiences of family caregivers of persons with dementia at the end of life. +4 more findings

  19. 2012-10-19

    Longitudinal relationships between subjective fatigue, cognitive function, and everyday functioning in old age

    ✓ Peer-reviewed Prevention trials International psychogeriatrics

    Key finding: Future interventions should address subjective fatigue when managing cognitive and functional abilities in community-dwelling older adults. +2 more findings

  20. 2012-10-16

    Physical activity, brain plasticity, and Alzheimer's disease

    ✓ Peer-reviewed Prevention trials Archives of medical research

    Key finding: The epidemiological literature provides compelling evidence that greater amounts of physical activity are associated with a reduced risk of dementia in late life. +2 more findings

  21. 2012-10-15

    Cognitive reserve in ageing and Alzheimer's disease

    ✓ Peer-reviewed Risk factors The Lancet Neurology

    Key finding: The concept of cognitive reserve provides an explanation for differences between individuals in susceptibility to age-related brain changes or pathology related to Alzheimer's disease, whereby some people can tolerate more of these changes than others and maintain function. +3 more findings

  22. 2012-10-15

    Insulin resistance, brain atrophy, and cognitive performance in late middle-aged adults

    ✓ Peer-reviewed Brain tissue and pathology Diabetes care

    Key finding: This longitudinal study examined whether insulin resistance among late middle-aged, cognitively healthy individuals was associated with 1) less gray matter in Alzheimer disease-sensitive brain regions and 2) worse cognitive performance. +3 more findings

  23. 2012-10-15

    Mindfulness-based stress reduction for family caregivers: a randomized controlled trial

    ✓ Peer-reviewed Disparities The Gerontologist

    Key finding: MBSR was more effective at improving overall mental health, reducing stress, and decreasing depression than CCES. +1 more finding

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