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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 19,226–19,250 of 27,380 studies, newest first · page 770 of 1096.

September 2012 25

  1. 2012-09-12

    Vascular burden and Alzheimer disease pathologic progression

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: Increased WMHs are associated with aging, decreased glucose metabolism, and decline in executive function but do not affect AD-specific pathologic progression, suggesting that the vascular contribution to dementia is probably additive although not necessarily independent of the amyloid pathway. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2012-09-12

    Indicators of amyloid burden in a population-based study of cognitively normal elderly

    ✓ Peer-reviewed Genetics Neurology

    Key finding: Age and APOE genotype are useful predictors of the likelihood of significant amyloid accumulation, but discrimination is modest. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2012-09-11

    δ-Catenin is genetically and biologically associated with cortical cataract and future Alzheimer-related structural and functional brain changes

    ✓ Peer-reviewed Brain scans and imaging PloS one

    Key finding: Multiple lines of evidence suggest that specific subtypes of age-related cataract (ARC) and Alzheimer disease (AD) are related etiologically. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2012-09-10

    Tumor necrosis factor-induced cerebral insulin resistance in Alzheimer's disease links numerous treatment rationales

    ✓ Peer-reviewed Drug development Pharmacological reviews

    Key finding: When this is incorporated into the bigger picture, it becomes evident that the interventions we discuss are not competing alternatives but equally valid approaches to correcting different parts of the same pathway to Alzheimer's disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2012-09-08

    A European multicentre PET study of fibrillar amyloid in Alzheimer's disease

    ✓ Peer-reviewed Mild cognitive impairment European journal of nuclear medicine and molecular imaging

    Key finding: [(11)C]PIB retention in the neocortical and subcortical brain regions was significantly higher in AD patients than in age-matched controls. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2012-09-08

    Metal dyshomeostasis and oxidative stress in Alzheimer's disease

    ✓ Peer-reviewed Caregiving Neurochemistry international

    Key finding: Accumulating evidence suggests that copper, zinc, and iron homeostasis may become perturbed in Alzheimer's disease and could underlie an increased oxidative stress burden.

    Full summary, score breakdown and related studies → Original source

  7. 2012-09-07

    Geographic variation of epilepsy for older Americans: How close to the geographic variation of stroke?

    ✓ Peer-reviewed Risk factors Epilepsia

    Key finding: Of 1,212,015 beneficiaries, 11.9 per 1,000 had prevalent and 2.9 new cases of epilepsy. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2012-09-07

    Anxiety is related to Alzheimer cerebrospinal fluid markers in subjects with mild cognitive impairment

    ✓ Peer-reviewed Tau biomarkers Psychological medicine

    Key finding: Anxiety, apathy and depression are common in subjects with mild cognitive impairment (MCI) and may herald Alzheimer's disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2012-09-05

    Walking stabilizes cognitive functioning in Alzheimer's disease (AD) across one year

    ✓ Peer-reviewed Disparities Archives of gerontology and geriatrics

    Key finding: Our results demonstrated that the patients spent little time engaged in physical activity in general, their overall activity levels decreased over time, and this was paired with a change in global cognition (e.g., MMSE total score) and affect/mood (e.g., POMS score). +2 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2012-09-04

    Role of genes linked to sporadic Alzheimer's disease risk in the production of β-amyloid peptides

    ✓ Peer-reviewed Biomarkers Proceedings of the National Academy of Sciences of the United States of America

    Key finding: However, unlike the genes underlying familial AD, late onset AD-susceptibility genes do not specifically alter the Aβ42/40 ratios and suggest that these genes probably contribute to AD through distinct mechanisms.

    Full summary, score breakdown and related studies → Original source

  11. 2012-09-03

    Engaging life in two Irish nursing home units for people with dementia: Quantitative comparisons before and after implementing household environments

    ✓ Peer-reviewed Health systems and care delivery Aging & Mental Health

    Key finding: The results were consistent for both nursing homes and data were aggregated. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2012-09-03

    Neuroimaging correlates of pathologically defined subtypes of Alzheimer's disease: a case-control study

    ✓ Peer-reviewed Caregiving The Lancet. Neurology

    Key finding: Compared with typical AD, hippocampal-sparing AD has more neurofibrillary tangles in the cortex and fewer in the hippocampus, whereas the opposite pattern is seen in limbic-predominant AD.

    Full summary, score breakdown and related studies → Original source

  13. 2012-09-03

    The natural history of cognitive decline in Alzheimer's disease

    ✓ Peer-reviewed Getting a diagnosis Psychology and aging

    Key finding: The results indicate that cognitive decline in AD begins many years before dementia is diagnosed and accelerates during the course of the disease.

    Full summary, score breakdown and related studies → Original source

  14. 2012-09-01

    Alzheimer's disease, β-amyloid, glutamate, NMDA receptors and memantine--searching for the connections

    ✓ Peer-reviewed Treatments British journal of pharmacology

    Key finding: Most recent evidence indicates that soluble oligomers rather than plaques are the major cause of synaptic dysfunction and ultimately neurodegeneration.

    Full summary, score breakdown and related studies → Original source

  15. 2012-09-01

    Natural products as a rich source of tau-targeting drugs for Alzheimer's disease

    ✓ Peer-reviewed Drug development Future medicinal chemistry

    Key finding: Alzheimer's disease (AD) is a neurodegenerative disorder and the most common form of dementia, affecting more than 5.4 million people in the USA. +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2012-09-01

    Disruption of the sleep-wake cycle and diurnal fluctuation of β-amyloid in mice with Alzheimer's disease pathology

    ✓ Peer-reviewed Tau biomarkers Science translational medicine

    Key finding: These data suggest that Aβ aggregation disrupts the sleep-wake cycle and diurnal fluctuation of Aβ.

    Full summary, score breakdown and related studies → Original source

  17. 2012-09-01

    Hippocampal sclerosis--origins and imaging

    ✓ Peer-reviewed Hippocampus size on brain scans Epilepsia

    Key finding: If adequate MRI shows no structural correlate in patients with MTLE, functional imaging studies are valuable, especially if they are in agreement with ictal electroencephalography (EEG) findings. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2012-09-01

    Assessment and management of pain, with particular emphasis on central neuropathic pain, in moderate to severe dementia

    ✓ Peer-reviewed End-of-life care Drugs & aging

    Key finding: Concerning pain assessment, the findings of this review suggest that self-report pain rating scales, in particular the Verbal Rating Scale, the Horizontal Visual Analogue Scale and the Faces Pain Scale can be administered to patients in a more advanced stage of dementia.

    Full summary, score breakdown and related studies → Original source

  19. 2012-09-01

    Atypical antipsychotic use in patients with dementia: managing safety concerns

    ✓ Peer-reviewed Clinical safety The American journal of psychiatry

    Key finding: Neuropsychiatric symptoms such as agitation and delusions occur commonly in elderly patients with dementia and often cause significant distress. +2 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2012-09-01

    Delirium and Long-term Cognitive Trajectory Among Persons With Dementia

    ✓ Peer-reviewed Clinical safety Archives of internal medicine

    Key finding: Delirium is highly prevalent among persons with AD who are hospitalized and is associated with an increased rate of cognitive deterioration that is maintained for up to 5 years. +4 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2012-09-01

    Is the amyloid hypothesis of Alzheimer's disease therapeutically relevant?

    ✓ Peer-reviewed Disease mechanisms The Biochemical journal

    Key finding: However, AD is likely to be a complex disease driven by multiple factors. +4 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2012-09-01

    Antibody-aided clearance of extracellular α-synuclein prevents cell-to-cell aggregate transmission

    ✓ Peer-reviewed Inflammation and the immune system The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Previous studies demonstrated that immunization against α-synuclein resulted in reduced α-synuclein accumulation and synaptic loss in a transgenic (tg) mouse model, highlighting the potential for immunotherapy. +3 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2012-09-01

    Excessive sleepiness is predictive of cognitive decline in the elderly

    ✓ Peer-reviewed Cognitive tests and assessment Sleep

    Key finding: Study objectives To examine the association of sleep complaints reported at baseline (insomnia complaints and excessive daytime sleepiness (EDS)) and medication, with cognitive decline in community-dwelling elderly. +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2012-09-01

    Vitamin D, cognition, and dementia: a systematic review and meta-analysis

    ✓ Peer-reviewed Cognitive tests and assessment Neurology

    Key finding: Five databases were searched for English-language studies up to August 2010, and included all study designs with a comparative group. +3 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2012-09-01

    Fluid biomarkers in Alzheimer disease

    ✓ Peer-reviewed Tau biomarkers Cold Spring Harbor perspectives in medicine

    Key finding: This knowledge has been translated into new drug candidates with putative disease-modifying effects, which are now being tested in clinical trials. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →