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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 18,851–18,875 of 27,380 studies, newest first · page 755 of 1096.

February 2013 25

  1. 2013-02-26

    Retinal vascular biomarkers for early detection and monitoring of Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging Translational psychiatry

    Key finding: This report presents results from analysis of retinal photographs from AD and healthy control participants from the Australian Imaging, Biomarkers and Lifestyle (AIBL) Flagship Study of Ageing.

    Full summary, score breakdown and related studies → Original source

  2. 2013-02-26

    Symptom burden, palliative care need and predictors of physical and psychological discomfort in two UK hospitals

    ✓ Peer-reviewed End-of-life care BMC palliative care

    Key finding: The paper highlights elevated levels of burden experienced by patients with palliative care requirements. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2013-02-24

    A review on cholinesterase inhibitors for Alzheimer's disease

    ✓ Peer-reviewed Treatments Archives of pharmacal research

    Key finding: Furthermore, it has been also demonstrated that both acetylcholinesterase and butrylcholinesterase (BuChE) play an important role in Aβ-aggregation during the early stages of senile plaque formation.

    Full summary, score breakdown and related studies → Original source

  4. 2013-02-22

    Changes in mortality and causes of death in the Swedish Down syndrome population

    ✓ Peer-reviewed Down syndrome and Alzheimer's American journal of medical genetics. Part A

    Key finding: Dementia was not reported in any subjects with DS before 40 years of age, but was a main or contributing cause of death in 30% of the older subjects. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2013-02-22

    An MRI rating scale for amyloid-related imaging abnormalities with edema or effusion

    ✓ Peer-reviewed Treatments AJNR. American journal of neuroradiology

    Key finding: The proposed rating scale provides a reliable and easily implemented instrument to grade ARIA-E imaging findings.

    Full summary, score breakdown and related studies → Original source

  6. 2013-02-22

    Brain-wide pathway for waste clearance captured by contrast-enhanced MRI

    ✓ Peer-reviewed Tau biomarkers The Journal of clinical investigation

    Key finding: Here we provide proof of concept that glymphatic pathway function can be measured using a clinically relevant imaging technique. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2013-02-22

    Five things physicians and patients should question in hospice and palliative medicine

    ✓ Peer-reviewed End-of-life care Journal of pain and symptom management

    Key finding: The American Board of Internal Medicine Foundation's Choosing Wisely® campaign is a multiyear effort to encourage physician leadership in reducing harmful or inappropriate resource utilization. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2013-02-21

    The current and projected economic burden of Parkinson's disease in the United States

    ✓ Peer-reviewed Costs and economics Movement disorders : official journal of the Movement Disorder Society

    Key finding: The national economic burden of PD exceeds $14.4 billion in 2010 (approximately $22,800 per patient). +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2013-02-21

    Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Aβ and differential drug responsiveness

    ✓ Peer-reviewed Risk genes beyond APOE Cell stem cell

    Key finding: Differential manifestation of ER stress and DHA responsiveness may help explain variable clinical results obtained with the use of DHA treatment and suggests that DHA may in fact be effective for a subset of patients.

    Full summary, score breakdown and related studies → Original source

  10. 2013-02-21

    Moving in: adjustment of people living with dementia going into a nursing home and their families

    ✓ Peer-reviewed Clinical safety International psychogeriatrics

    Key finding: Adjustment to admission to residential care can be difficult for people with dementia and their family caregivers.

    Full summary, score breakdown and related studies → Original source

  11. 2013-02-20

    Nonpharmacological enhancement of cognitive function in Parkinson's disease: a systematic review

    ✓ Peer-reviewed Prevention trials Movement disorders : official journal of the Movement Disorder Society

    Key finding: The methodology, study populations, interventions, outcomes, control groups, analyses, results, limitations, biases, and evidence levels of all reviewed studies were described. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2013-02-19

    APOE and BCHE as modulators of cerebral amyloid deposition: a florbetapir PET genome-wide association study

    ✓ Peer-reviewed Genetics Molecular psychiatry

    Key finding: Deposition of amyloid-β (Aβ) in the cerebral cortex is thought to be a pivotal event in Alzheimer's disease (AD) pathogenesis with a significant genetic contribution. +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2013-02-19

    Soluble amyloid precursor protein β as blood-based biomarker of Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Translational psychiatry

    Key finding: Significantly decreased plasma concentrations in the AD group compared with both the control group and the bvFTD group were detected for sAPPβ (P = 0.03 for both group comparisons), but not for sAPPα. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2013-02-19

    Advanced glycation end-products disrupt the blood-brain barrier by stimulating the release of transforming growth factor-β by pericytes and vascular endothelial growth factor and matrix metalloproteinase-2 by endothelial cells in vitro

    ✓ Peer-reviewed Disease mechanisms Neurobiology of aging

    Key finding: The breakdown of the blood-brain barrier (BBB) is associated with dementia in patients with type 2 diabetes mellitus (T2DM). +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2013-02-19

    Cerebral amyloid angiopathy burden associated with leukoaraiosis: a positron emission tomography/magnetic resonance imaging study

    ✓ Peer-reviewed Brain scans and imaging Annals of neurology

    Key finding: These findings support the idea that vascular amyloid burden directly contributes to chronic cerebral ischemia and highlights the possible utility of amyloid imaging as a marker of CAA severity. +1 more finding

    Full summary, score breakdown and related studies → Original source

  16. 2013-02-18

    Effectiveness of cognitive training for Chinese elderly in Hong Kong

    ✓ Peer-reviewed Prevention trials Clinical interventions in aging

    Key finding: Subjects with lower education level were associated with better cognitive response to the cognitive-training program. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2013-02-18

    Efficacy of a cognitive intervention program in patients with mild cognitive impairment

    ✓ Peer-reviewed Prevention trials International psychogeriatrics

    Key finding: These results suggest that persons with MCI can improve their performance on cognitive and functional measures when provided with early cognitive training and it could persist in a long-term follow-up. +1 more finding

    Full summary, score breakdown and related studies → Original source

  18. 2013-02-16

    Structural changes in hippocampal subfields in major depressive disorder: a high-field magnetic resonance imaging study

    ✓ Peer-reviewed Hippocampus size on brain scans Biological psychiatry

    Key finding: Hippocampal volumes in unmedicated MDD showed evidence of localization to specific subfields and subregions, findings that appear, on the surface, consistent with preclinical evidence for localized mechanisms of hippocampal neuroplasticity.

    Full summary, score breakdown and related studies → Original source

  19. 2013-02-15

    Ca2+‐dependent endoplasmic reticulum stress correlates with astrogliosis in oligomeric amyloid β‐treated astrocytes and in a model of A lzheimer's disease

    ✓ Peer-reviewed Biomarkers Aging Cell

    Key finding: Here, we found that amyloid β oligomers caused a cytoplasmic Ca(2+) increase in cultured astrocytes, which was reduced by inhibitors of PLC and ER Ca(2+) release. +2 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2013-02-14

    Linking pesticide exposure and dementia: what is the evidence?

    ✓ Peer-reviewed Risk factors Toxicology

    Key finding: At the cellular and molecular level, the mechanism of action of many classes of pesticides suggests that these compounds could be, at least partly, accountable for the neurodegeneration accompanying AD and other dementias.

    Full summary, score breakdown and related studies → Original source

  21. 2013-02-14

    TREM2 in Alzheimer's disease

    ✓ Peer-reviewed TREM2 and immune genetics Molecular neurobiology

    Key finding: The reduced function of TREM2 was speculated to be the main cause in the pathogenic effects of this risk variant, and TREM2 is highly expressed in white matter, as well as in the hippocampus and neocortex, which is partly consistent with the pathological features reported in AD brain, indicating the possible involvement of TREM2 in AD pathogenesis. +3 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2013-02-14

    Amyloid β-peptide (1-42)-induced oxidative stress in Alzheimer disease: importance in disease pathogenesis and progression

    ✓ Peer-reviewed Risk genes beyond APOE Antioxidants & redox signaling

    Key finding: Alzheimer disease (AD) is an age-related neurodegenerative disease. +3 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2013-02-12

    [(18)F]T807, a novel tau positron emission tomography imaging agent for Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: [(18)F]T807 demonstrates high affinity and selectivity to PHF-tau as well as favorable in vivo properties, making this a promising candidate as an imaging agent for AD. +2 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2013-02-12

    Unconventional translation of C9ORF72 GGGGCC expansion generates insoluble polypeptides specific to c9FTD/ALS

    ✓ Peer-reviewed Lewy body dementia Neuron

    Key finding: These findings have significant implications for treatment strategies directed at RAN-translated peptides and their aggregation and the RNA structures necessary for their production.

    Full summary, score breakdown and related studies → Original source

  25. 2013-02-12

    Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology

    ✓ Peer-reviewed Genetics Molecular psychiatry

    Key finding: Finally, the 3 bp insertion was associated with Tau but not Amyloid loads in AD brains.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →