alzhub.org
Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 16,601–16,625 of 27,380 studies, newest first · page 665 of 1096.

October 2015 25

  1. 2015-10-27

    The burden of health care costs for patients with dementia in the last 5 years of life

    ✓ Peer-reviewed Caregiving Annals of internal medicine

    Key finding: Health care expenditures among persons with dementia were substantially larger than those for other diseases, and many of the expenses were uncovered (uninsured).

    Full summary, score breakdown and related studies → Original source

  2. 2015-10-26

    Integrating longitudinal information in hippocampal volume measurements for the early detection of Alzheimer's disease

    ✓ Peer-reviewed Long-term cohort studies NeuroImage

    Key finding: Structural MRI measures for monitoring Alzheimer's Disease (AD) progression are becoming instrumental in the clinical practice, and more so in the context of longitudinal studies. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2015-10-24

    The prevalence of neuropsychiatric symptoms in Alzheimer's disease: Systematic review and meta-analysis

    ✓ Peer-reviewed Risk factors Journal of affective disorders

    Key finding: NPS were observed to be highly prevalent in AD patients. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2015-10-24

    Microglial genes regulating neuroinflammation in the progression of Alzheimer's disease

    ✓ Peer-reviewed TREM2 and immune genetics Current opinion in neurobiology

    Key finding: Microglia act as sentinel and protective cells, but may become inappropriately reactive in AD to drive neuropathology. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2015-10-24

    Social activity, cognitive decline and dementia risk: a 20-year prospective cohort study

    ✓ Peer-reviewed Prevention and risk BMC public health

    Key finding: We observed a complex series of relationships between social-environment variables and cognitive decline and dementia. +2 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2015-10-23

    Alterations in stress granule dynamics driven by TDP-43 and FUS: a link to pathological inclusions in ALS?

    ✓ Peer-reviewed Brain tissue and pathology Frontiers in cellular neuroscience

    Key finding: Since their discovery in 1999, over 120 proteins have been described to be localized to these structures (in 154 publications). +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2015-10-23

    The roles of lipid and glucose metabolism in modulation of β-amyloid, tau, and neurodegeneration in the pathogenesis of Alzheimer disease

    ✓ Peer-reviewed Genetics Frontiers in aging neuroscience

    Key finding: Apolipoprotein E (ApoE) and several genes related to AD have recently been identified by genome-wide association studies (GWAS) as being closely linked to lipid metabolism. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2015-10-21

    Review of endocrine disorders associated with environmental toxicants and possible involved mechanisms

    ✓ Peer-reviewed Risk factors Life sciences

    Key finding: Clinical evidence, experimental models, and epidemiological studies suggest that EDC have major risks for human by targeting different organs and systems in the body. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2015-10-21

    Common polygenic variation enhances risk prediction for Alzheimer's disease

    ✓ Peer-reviewed Genetics Brain : a journal of neurology

    Key finding: Polygenic score analysis tested whether the alleles identified to associate with disease in one sample set were significantly enriched in the cases relative to the controls in an independent sample. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2015-10-21

    Mediterranean diet and brain structure in a multiethnic elderly cohort

    ✓ Peer-reviewed Prevention trials Neurology

    Key finding: Among older adults, MeDi adherence was associated with less brain atrophy, with an effect similar to 5 years of aging. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2015-10-21

    Dietary Patterns and Socioeconomic Status in the Very Old: The Newcastle 85+ Study

    ✓ Peer-reviewed Risk factors PLoS ONE

    Key finding: We identified three distinct DP (characterised as 'High Red Meat', 'Low Meat', and 'High Butter') that varied with key sociodemographic, health and functioning measures. 'Low Meat' participants were more advantaged (i.e. higher education and occupational class, and lived in more affluent areas in owned homes), were least disabled, cognitively impaired, and depressed, and were more physically active than those in the other DP. +2 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2015-10-20

    Organophosphate pesticide exposure and neurodegeneration

    ✓ Peer-reviewed Risk factors Cortex; a journal devoted to the study of the nervous system and behavior

    Key finding: In particular this review aims to discuss common targets and pathways identified which may underlie the functional deficits associated with both pesticide exposure and neurodegeneration.

    Full summary, score breakdown and related studies → Original source

  13. 2015-10-20

    Speaking in Alzheimer's Disease, is That an Early Sign? Importance of Changes in Language Abilities in Alzheimer's Disease

    ✓ Peer-reviewed Digital health tools Frontiers in aging neuroscience

    Key finding: However, knowledge about the unique features of the language problems associated with different dementia variants still has to be improved and refined.

    Full summary, score breakdown and related studies → Original source

  14. 2015-10-20

    The age factor in Alzheimer's disease

    ✓ Peer-reviewed How common it is Genome medicine

    Key finding: A recent genome-wide study identified a locus on chromosome 17 associated with the age at onset, and a specific variant in CCL11 is probably responsible for the association.

    Full summary, score breakdown and related studies → Original source

  15. 2015-10-19

    Smartphone for smart living: Using new technologies to cope with everyday limitations in semantic dementia

    ✓ Peer-reviewed Cognitive tests and assessment Neuropsychological Rehabilitation

    Key finding: New technologies have considerable potential to support people with semantic dementia-a form of progressive aphasia-in their everyday lives, but evidence is still sparse. +1 more finding

    Full summary, score breakdown and related studies → Original source

  16. 2015-10-19

    Cerebral correlates of cognitive reserve

    ✓ Peer-reviewed Risk factors Psychiatry research. Neuroimaging

    Key finding: Structural MRI exams were acquired in about 50% of the sample from whom a subsample were recruited into an additional fMRI study. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2015-10-17

    Reversal effects of crocin on amyloid β-induced memory deficit: Modification of autophagy or apoptosis markers

    ✓ Peer-reviewed Disease mechanisms Pharmacology, biochemistry, and behavior

    Key finding: Beta amyloid hypothesis is the main theoretical research framework for Alzheimer's disease which states that extracellular aggregation of beta amyloid results in synaptic loss and eventually cell apoptosis. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2015-10-15

    Montreal Cognitive Assessment: One Cutoff Never Fits All

    ✓ Peer-reviewed Cognitive tests and assessment Stroke

    Key finding: The objective of this study is to examine the discrepancy between single versus age and education corrected cutoff scores in classifying performance on the Montreal Cognitive Assessment (MoCA) in patients with stroke or transient ischemic attack. +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2015-10-15

    Working memory and executive function decline across normal aging, mild cognitive impairment, and Alzheimer's disease

    ✓ Peer-reviewed Mild cognitive impairment BioMed research international

    Key finding: Examples of executive dysfunction in AD include poor selective and divided attention, failed inhibition of interfering stimuli, and poor manipulation skills. +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2015-10-15

    Clinical Practice Guideline for the Treatment of Intrinsic Circadian Rhythm Sleep-Wake Disorders: Advanced Sleep-Wake Phase Disorder (ASWPD), Delayed Sleep-Wake Phase Disorder (DSWPD), Non-24-Hour Sleep-Wake Rhythm Disorder (N24SWD), and Irregular Sleep-Wake Rhythm Disorder (ISWRD). An Update for 2015: An American Academy of Sleep Medicine Clinical Practice Guideline

    ✓ Peer-reviewed Risk factors Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine

    Key finding: A systematic literature review and meta-analyses (where appropriate) were performed and the GRADE approach was used to update the previous American Academy of Sleep Medicine Practice Parameters on the treatment of intrinsic circadian rhythm sleep-wake disorders. +4 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2015-10-14

    Use of amyloid-PET to determine cutpoints for CSF markers: A multicenter study

    ✓ Peer-reviewed Biomarkers Neurology

    Key finding: Amyloid-PET-based CSF Aβ42 cutpoints were higher and tended to reduce intercenter variability compared with clinical-based cutpoints. +2 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2015-10-13

    Dissecting Alzheimer disease in Down syndrome using mouse models

    ✓ Peer-reviewed Down syndrome and Alzheimer's Frontiers in behavioral neuroscience

    Key finding: Down syndrome (DS) is a common genetic condition caused by the presence of three copies of chromosome 21 (trisomy 21). +4 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2015-10-12

    The Role of Oxidative Stress in Neurodegenerative Diseases

    ✓ Peer-reviewed Disease mechanisms Experimental neurobiology

    Key finding: Previous studies have demonstrated that oxidative stress plays a central role in a common pathophysiology of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease. +1 more finding

    Full summary, score breakdown and related studies → Original source

  24. 2015-10-12

    Rescue of long-range circuit dysfunction in Alzheimer's disease models

    ✓ Peer-reviewed Brain scans and imaging Nature neuroscience

    Key finding: Alzheimer's disease (AD) is associated with defects of synaptic connectivity. +1 more finding

    Full summary, score breakdown and related studies → Original source

  25. 2015-10-12

    Replacement of brain-resident myeloid cells does not alter cerebral amyloid-β deposition in mouse models of Alzheimer's disease

    ✓ Peer-reviewed TREM2 and immune genetics The Journal of experimental medicine

    Key finding: However, assigning functional roles to myeloid cell subtypes has been problematic, and the potential for peripheral myeloid cells to alleviate AD pathology remains unclear. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →