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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 18,751–18,775 of 27,380 studies, newest first · page 751 of 1096.

April 2013 25

  1. 2013-04-10

    Amyloid imaging and CSF biomarkers in predicting cognitive impairment up to 7.5 years later

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: Abnormal levels of all biomarkers were associated with faster time to cognitive impairment, and some participants with abnormal biomarker levels remained cognitively normal for up to 6.6 years. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2013-04-09

    Consistent decrease in global DNA methylation and hydroxymethylation in the hippocampus of Alzheimer's disease patients

    ✓ Peer-reviewed Genetics Neurobiology of aging

    Key finding: Recent studies indicate that DNA methylation and DNA hydroxymethylation are 2 important epigenetic mechanisms that regulate gene expression in the aging brain. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2013-04-09

    Variants in triggering receptor expressed on myeloid cells 2 are associated with both behavioral variant frontotemporal lobar degeneration and Alzheimer's disease

    ✓ Peer-reviewed TREM2 and immune genetics Neurobiology of aging

    Key finding: TREM2 mutations are the genetic basis for a condition characterized by polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL) and an early-onset dementia syndrome. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2013-04-08

    Functional impairment of microglia coincides with Beta-amyloid deposition in mice with Alzheimer-like pathology

    ✓ Peer-reviewed Inflammation and the immune system PloS one

    Key finding: The significance of this microglial phenotype and the impact of microglia for disease progression have remained controversial. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2013-04-06

    Amyloid PET in clinical practice: Its place in the multidimensional space of Alzheimer's disease

    ✓ Peer-reviewed Biomarkers NeuroImage. Clinical

    Key finding: Amyloid imaging is currently introduced to the market for clinical use. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2013-04-05

    Cognitive training improves sleep quality and cognitive function among older adults with insomnia

    ✓ Peer-reviewed Prevention trials PloS one

    Key finding: Study objectives To investigate the effect of an eight-week, home-based, personalized, computerized cognitive training program on sleep quality and cognitive performance among older adults with insomnia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2013-04-04

    Perivascular spaces are associated with atherosclerosis: an insight from the Northern Manhattan Study

    ✓ Peer-reviewed Disparities AJNR. American journal of neuroradiology

    Key finding: These results suggest that mechanisms leading to atherosclerosis might also lead to an increased number of perivascular spaces. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2013-04-04

    Monetary Costs of Dementia in the United States

    ✓ Peer-reviewed Costs and economics New England Journal of Medicine

    Key finding: Total 2010 US monetary cost of dementia estimated at $157-$215 billion depending on informal-care valuation method +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2013-04-03

    Are Empirically-Derived Subtypes of Mild Cognitive Impairment Consistent with Conventional Subtypes?

    ✓ Peer-reviewed Prevention trials Journal of the International Neuropsychological Society

    Key finding: Given the importance of identifying dementia prodromes for future treatment efforts, we examined two methods of diagnosing mild cognitive impairment (MCI) and determined whether empirically-derived MCI subtypes of these diagnostic methods were consistent with one another as well as with conventional MCI subtypes (i.e., amnestic, non-amnestic, single-domain, multi-domain). +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2013-04-03

    Neuropsychiatric symptoms in Alzheimer's disease: past progress and anticipation of the future

    ✓ Peer-reviewed Risk factors Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Being cognizant of this, in 2010 the Alzheimer's Association convened a research roundtable on the topic of NPS in AD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2013-04-03

    Expanded GGGGCC repeat RNA associated with amyotrophic lateral sclerosis and frontotemporal dementia causes neurodegeneration

    ✓ Peer-reviewed Brain scans and imaging Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Here we developed both Drosophila and mammalian models of this expanded hexanucleotide repeat and showed that expression of the expanded GGGGCC repeat RNA (rGGGGCC) is sufficient to cause neurodegeneration. +2 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2013-04-03

    Neurodegenerative disease status and post-mortem pathology in idiopathic rapid-eye-movement sleep behaviour disorder: an observational cohort study

    ✓ Peer-reviewed Getting a diagnosis The Lancet. Neurology

    Key finding: Our findings indicate that in most patients diagnosed with IRBD this parasomnia represents the prodromal phase of a Lewy body disorder.

    Full summary, score breakdown and related studies → Original source

  13. 2013-04-03

    Association of diabetes with amnestic and nonamnestic mild cognitive impairment

    ✓ Peer-reviewed Prevention and risk Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Diabetes was associated with an increased risk of MCI in elderly persons. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2013-04-02

    The role of palliative care in patients with neurological diseases

    ✓ Peer-reviewed End-of-life care Nature reviews. Neurology

    Key finding: Challenges in the palliative care of patients with incurable neurological diseases include the broad spectrum of the rate of symptom progression, a lack of reliable prognostic markers, scarcity of evidence for efficacy of symptomatic treatments, and a high prevalence of difficulties with communication, cognitive impairment and behavioural disturbances. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2013-04-02

    The endogenous tryptophan metabolite and NAD+ precursor quinolinic acid confers resistance of gliomas to oxidative stress

    ✓ Peer-reviewed Inflammation and the immune system Cancer research

    Key finding: Here, we show that quinolinic acid accumulated in human gliomas and was associated with a malignant phenotype. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2013-04-02

    Increased blood-brain barrier vulnerability to systemic inflammation in an Alzheimer disease mouse model

    ✓ Peer-reviewed Risk genes beyond APOE Neurobiology of aging

    Key finding: Although it is well know that these symptoms often are triggered by infection of peripheral organs, the underlying mechanisms for these pathological conditions are still unclear. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2013-04-02

    SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians

    ✓ Peer-reviewed Genetics PloS one

    Key finding: Subsequent analysis combining results for several SORL1 SNPs in the Japanese, Korean (339 cases, 1,129 controls) and Caucasians (11,840 AD cases, 10,931 controls) revealed genome wide significance with rs11218343 (P = 1.77×10(-9)) and rs3781834 (P = 1.04×10(-8)).

    Full summary, score breakdown and related studies → Original source

  18. 2013-04-01

    Meta-analysis of amyloid-cognition relations in cognitively normal older adults

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: Based on this meta-analytic survey of the literature, increased amyloid burden has small but nontrivial associations with specific domains of cognitive performance in individuals who are currently cognitively normal. +2 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2013-04-01

    Methodology of China's national study on the evaluation, early recognition, and treatment of psychological problems in the elderly: the China Longitudinal Aging Study (CLAS)

    ✓ Peer-reviewed Prevention trials Shanghai archives of psychiatry

    Key finding: Cognitive and depressive disorders are common in elderly Chinese and are becoming an increasingly important public health problem, partly because of the rapid aging of the population. +1 more finding

    Full summary, score breakdown and related studies → Original source

  20. 2013-04-01

    Body mass index, lifestyles, physical performance and cognitive decline: the "Treviso Longeva (TRELONG)" study

    ✓ Peer-reviewed Prevention trials The journal of nutrition, health & aging

    Key finding: Age and higher baseline BMI, independent of gender, and other confounding factors, are risk factors for cognitive decline. +3 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2013-04-01

    Disruption of blood-brain barrier in Alzheimer disease pathogenesis

    ✓ Peer-reviewed Disease mechanisms Tissue barriers

    Key finding: We found enhanced permeability, decreased zonula occludin-1 (ZO-1) expression and increased intracellular calcium and MMP secretion in endothelial cells exposed to Aβ1-42. +2 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2013-04-01

    GWAS of Cerebrospinal Fluid Tau Levels Identifies Risk Variants for Alzheimer’s Disease

    ✓ Peer-reviewed Genetics Neuron

    Full summary, score breakdown and related studies → Original source

  23. 2013-04-01

    Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

    ✓ Peer-reviewed Genetics Cell

    Key finding: LOAD reconfigures specific portions of the molecular interaction structure. +2 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2013-04-01

    Acute and chronic traumatic encephalopathies: pathogenesis and biomarkers

    ✓ Peer-reviewed Brain tissue and pathology Nature reviews. Neurology

    Key finding: Such awareness has been stimulated mainly by reports of progressive neurological dysfunction in athletes exposed to repetitive concussions in high-impact sports such as boxing and American football, and by the rising number of TBIs in war veterans who are now more likely to survive explosive blasts owing to improved treatment. +3 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2013-04-01

    Amyloid precursor protein controls cholesterol turnover needed for neuronal activity

    ✓ Peer-reviewed Risk genes beyond APOE EMBO molecular medicine

    Key finding: APP cleavage is tightly regulated by cholesterol and APP fragments regulate lipid homeostasis. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →