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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 16,251–16,275 of 27,380 studies, newest first · page 651 of 1096.

March 2016 25

  1. 2016-03-03

    A rare coding variant in TREM2 increases risk for Alzheimer's disease in Han Chinese

    ✓ Peer-reviewed TREM2 and immune genetics Neurobiology of aging

    Key finding: This association was not successfully replicated in Han Chinese, where this variant was rare or even absent. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2016-03-03

    Assessment of the genetic variance of late-onset Alzheimer's disease

    ✓ Peer-reviewed TREM2 and immune genetics Neurobiology of aging

    Key finding: More than 20 common markers have been identified, which are associated with AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2016-03-02

    Amyloid-related imaging abnormalities from trials of solanezumab for Alzheimer's disease

    ✓ Peer-reviewed Treatments Alzheimer's & dementia (Amsterdam, Netherlands)

    Key finding: Asymptomatic ARIA-E was detected in solanezumab-treated and placebo-treated AD patients.

    Full summary, score breakdown and related studies → Original source

  4. 2016-03-02

    Cognitive Training Program to Improve Working Memory in Older Adults with MCI

    ✓ Peer-reviewed Prevention trials Clinical gerontologist

    Key finding: Cogmed was better on one core WM measure and had higher ratings of satisfaction. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2016-03-02

    Cerebrospinal fluid analysis detects cerebral amyloid-β accumulation earlier than positron emission tomography

    ✓ Peer-reviewed Long-term cohort studies Brain : a journal of neurology

    Key finding: Amyloid-β can be detected by analysis of cerebrospinal fluid amyloid-β42 or amyloid positron emission tomography, but it is unknown if any of the methods can identify an abnormal amyloid accumulation prior to the other. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2016-03-02

    Regional profiles of the candidate tau PET ligand 18F-AV-1451 recapitulate key features of Braak histopathological stages

    ✓ Peer-reviewed Mild cognitive impairment Brain : a journal of neurology

    Key finding: The estimated Braak stage was significantly associated with amyloid status, diagnostic category and measures of global cognition.

    Full summary, score breakdown and related studies → Original source

  7. 2016-03 month only

    The role of calsyntenin-3 in dystrophic neurite formation in Alzheimer's disease brain

    ✓ Peer-reviewed Disease mechanisms Geriatrics & gerontology international

    Key finding: β-Amyloid (Aβ) oligomers may play an important role in the early pathogenesis of Alzheimer's disease: cognitive impairment caused by synaptic dysfunction. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2016-03 month only

    [Significance and progress of DIAN/A4/API]

    ✓ Peer-reviewed Risk genes beyond APOE Nihon rinsho. Japanese journal of clinical medicine

    Key finding: It has revealed the biomarker changes in the mutation carrier's brain started as early as 20, even 25 years prior to symptoms.

    Full summary, score breakdown and related studies → Original source

  9. 2016-03-01

    The Locus Coeruleus: Essential for Maintaining Cognitive Function and the Aging Brain

    ✓ Peer-reviewed Risk factors Trends in cognitive sciences

    Key finding: However, brainstem regions play essential modulatory roles, and new evidence suggests that, among these, the integrity of the locus coeruleus (LC)-norepinephrine (NE) system plays a key role in determining late-life cognitive abilities.

    Full summary, score breakdown and related studies → Original source

  10. 2016-03-01

    Amyloid-Related Imaging Abnormalities (ARIA) in Immunotherapy Trials for Alzheimer's Disease: Need for Prognostic Biomarkers?

    ✓ Peer-reviewed Treatments Journal of Alzheimer's disease : JAD

    Key finding: Trial results demonstrated that the implementation of cerebrospinal fluid and Aβ-PET biomarkers improves trial enrichment and outcome, which has led to a change in targeting strategy as clinical trials would be conducted with earlier, even presymptomatic, stages of the disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2016-03-01

    First-In-Human safety and long-term exposure data for AAB-003 (PF-05236812) and biomarkers after intravenous infusions of escalating doses in patients with mild to moderate Alzheimer's disease

    ✓ Peer-reviewed Treatments Alzheimer's research & therapy

    Key finding: Based on integrated review of laboratory, electrocardiogram, adverse events, and MRI, AAB-003 was safe and well tolerated up to 8 mg/kg for up to 91 weeks (FIH and extension trials) in patients with mild to moderate AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2016-03-01

    The Feasibility of At-Home iPad Cognitive Testing For Use in Clinical Trials

    ✓ Peer-reviewed Cognitive tests and assessment The journal of prevention of Alzheimer's disease

    Key finding: Excellent reliability was observed among the 6 C3-PAD alternate versions (Cronbach alpha coefficient=0.93). +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2016-03-01

    Blood-Based Biomarker Candidates of Cerebral Amyloid Using PiB PET in Non-Demented Elderly

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: We then sought to extend our discovery findings by investigating whether our candidate biomarkers were also associated with brain amyloid burden in disease, in an independent cohort.

    Full summary, score breakdown and related studies → Original source

  14. 2016-03-01

    Dysphagia, dystussia, and aspiration pneumonia in elderly people

    ✓ Peer-reviewed Clinical safety Journal of thoracic disease

    Key finding: These observations suggest the need for a paradigm shift of the treatment for pneumonia in the elderly. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2016-03-01

    Dietary Factors and Cognitive Decline

    ✓ Peer-reviewed Prevention trials The journal of prevention of Alzheimer's disease

    Key finding: Although prospective epidemiological studies have observed that antioxidants, fatty acids, and B vitamins are associated with better cognitive functioning, randomized clinical trials have generally failed to confirm the value of any specific dietary component in improving neurocognition. +1 more finding

    Full summary, score breakdown and related studies → Original source

  16. 2016-03-01

    Preclinical Alzheimer's disease: Definition, natural history, and diagnostic criteria

    ✓ Peer-reviewed Getting a diagnosis Alzheimer s & Dementia

    During the past decade, a conceptual shift occurred in the field of Alzheimer's disease (AD) considering the disease as a continuum.

    Full summary, score breakdown and related studies → Original source

  17. 2016-03-01

    PET Imaging of Tau Deposition in the Aging Human Brain

    ✓ Peer-reviewed Brain scans and imaging Neuron

    Key finding: Older age was related to increased tracer retention in regions of the medial temporal lobe, which predicted worse episodic memory performance. +2 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2016-03-01

    Actin dynamics and cofilin-actin rods in alzheimer disease

    ✓ Peer-reviewed Inflammation and the immune system Cytoskeleton (Hoboken, N.J.)

    Key finding: Extracellular Aβ-containing plaques and intracellular phospho-tau-containing neurofibrillary tangles are postmortem pathologies required to confirm AD and have been the focus of most studies. +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2016-03-01

    Loss of VPS13C Function in Autosomal-Recessive Parkinsonism Causes Mitochondrial Dysfunction and Increases PINK1/Parkin-Dependent Mitophagy

    ✓ Peer-reviewed Lewy body dementia American journal of human genetics

    Key finding: VPS13C mutations are associated with a distinct form of early-onset parkinsonism characterized by rapid and severe disease progression and early cognitive decline; the pathological features were striking and reminiscent of diffuse Lewy body disease. +2 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2016-03-01

    C9orf72 is required for proper macrophage and microglial function in mice

    ✓ Peer-reviewed Lewy body dementia Science (New York, N.Y.)

    Key finding: Decreased expression of C9orf72 is seen in expansion carriers, suggesting that loss of function may play a role in disease. +1 more finding

    Full summary, score breakdown and related studies → Original source

  21. 2016-03-01

    MRI visual rating scales in the diagnosis of dementia: evaluation in 184 post-mortem confirmed cases

    ✓ Peer-reviewed Digital health tools Brain : a journal of neurology

    Key finding: Additionally, the performance of each scale to predict dementia pathology both individually and in combination was evaluated using a support vector classifier, which was compared with expert scan assessment to estimate clinical value. +1 more finding

    Full summary, score breakdown and related studies → Original source

  22. 2016-03-01

    The Science of Vascular Contributions to Cognitive Impairment and Dementia (VCID): A Framework for Advancing Research Priorities in the Cerebrovascular Biology of Cognitive Decline

    ✓ Peer-reviewed Caregiving Cellular and molecular neurobiology

    Key finding: Despite significant advances in our understanding of the biology of Alzheimer's disease (AD), the leading dementia diagnosis, the actual causes of dementia in affected individuals are unknown except for rare fully penetrant genetic forms. +1 more finding

    Full summary, score breakdown and related studies → Original source

  23. 2016-03-01

    Nutrition and risk of dementia: overview and methodological issues

    ✓ Peer-reviewed Prevention and risk Annals of the New York Academy of Sciences

    Key finding: A number of studies have examined dietary patterns, particularly the Mediterranean diet and DASH (Dietary Approaches to Stop Hypertension), neither of which is tailored to the specific foods and nutrients that have been identified as neuroprotective. +4 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2016-03-01

    Comparing the Effects of Multisensory Stimulation and Individualized Music Sessions on Elderly People with Severe Dementia: A Randomized Controlled Trial

    ✓ Peer-reviewed Treatments Journal of Alzheimer's disease : JAD

    Key finding: Outcomes were agitation (Cohen-Mansfield Agitation Inventory, CMAI), mood (Cornell Scale for Depression in Dementia, CSDD), anxiety (Rating Anxiety in Dementia, RAID), cognitive function (Severe Mini-Mental State Examination, SMMSE), and the overall severity of dementia (Bedford Alzheimer Nursing Severity Scale, BANS-S). +3 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2016-03-01

    CCR5 deficiency accelerates lipopolysaccharide-induced astrogliosis, amyloid-beta deposit and impaired memory function

    ✓ Peer-reviewed Biomarkers Oncotarget

    Key finding: Neuro-inflammation is associated with activation of astrocyte and amyloid-beta (Aβ) generations that lead to pathogenesis of Alzheimer disease (AD). +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →