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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 18,726–18,750 of 27,380 studies, newest first · page 750 of 1096.

April 2013 25

  1. 2013-04-23

    Improving end-of-life care in nursing homes: implementation and evaluation of an intervention to sustain quality of care

    ✓ Peer-reviewed End-of-life care Palliative medicine

    Key finding: A lower level of nursing support managed to sustain and build on the initial outcomes. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2013-04-23

    Factors regulating microglia activation

    ✓ Peer-reviewed TREM2 and immune genetics Frontiers in cellular neuroscience

    Key finding: However, it is especially important to create and maintain an intact tissue homeostasis to support the neuronal cells, which are very sensitive even to minor changes in their environment. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2013-04-19

    Neuroprotective effects of D-Ala(2)GIP on Alzheimer's disease biomarkers in an APP/PS1 mouse model

    ✓ Peer-reviewed Drug development Alzheimer's research & therapy

    Key finding: The results demonstrate that D-Ala(2)GIP has neuroprotective properties on key hallmarks found in AD. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2013-04-19

    Nardilysin in human brain diseases: both friend and foe

    ✓ Peer-reviewed Down syndrome and Alzheimer's Amino acids

    Key finding: Nardilysin is a metalloprotease that cleaves peptides, such as dynorphin-A, α-neoendorphin, and glucagon, at the N-terminus of arginine and lysine residues in dibasic moieties. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2013-04-18

    Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson’s disease

    ✓ Peer-reviewed Brain tissue and pathology Acta Neuropathologica

    Key finding: Our findings indicate that oligomer modulators provide a new approach for disease-modifying therapy in these diseases, for which only symptomatic treatment is available so far. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2013-04-18

    Glyphosate’s Suppression of Cytochrome P450 Enzymes and Amino Acid Biosynthesis by the Gut Microbiome: Pathways to Modern Diseases

    ✓ Peer-reviewed Disease mechanisms Entropy

    Key finding: Consequences are most of the diseases and conditions associated with a Western diet, which include gastrointestinal disorders, obesity, diabetes, heart disease, depression, autism, infertility, cancer and Alzheimer’s disease.

    Full summary, score breakdown and related studies → Original source

  7. 2013-04-18

    Impairment of proteostasis network in Down syndrome prior to the development of Alzheimer's disease neuropathology: redox proteomics analysis of human brain

    ✓ Peer-reviewed Down syndrome and Alzheimer's Biochimica et biophysica acta

    Key finding: Growing studies demonstrated that increased oxidative damage, accumulation of unfolded/damaged protein aggregates and dysfunction of intracellular degradative system are key players in neurodegenerative processes. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2013-04-18

    Subscale validation of the neuropsychiatric inventory questionnaire: comparison of Alzheimer's disease neuroimaging initiative and national Alzheimer's coordinating center cohorts

    ✓ Peer-reviewed Long-term cohort studies The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    Key finding: Neuropsychiatric symptoms are prevalent in mild cognitive impairment (MCI) and Alzheimer disease (AD) and commonly measured using the Neuropsychiatric Inventory (NPI). +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2013-04-18

    A phenotypic change but not proliferation underlies glial responses in Alzheimer disease

    ✓ Peer-reviewed Biomarkers The American journal of pathology

    Key finding: We conclude that a phenotypic change of existing glial cells, rather than a marked proliferation of glial precursors, accounts for the majority of the glial responses observed in the AD brain.

    Full summary, score breakdown and related studies → Original source

  10. 2013-04-17

    Saxagliptin: a dipeptidyl peptidase-4 inhibitor ameliorates streptozotocin induced Alzheimer's disease

    ✓ Peer-reviewed Drug development Neuropharmacology

    Key finding: Type 2 diabetes (T2D) is one of the major risk factors associated with Alzheimer's disease (AD). +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2013-04-17

    Twenty-year changes in dementia occurrence suggest decreasing incidence in central Stockholm, Sweden

    ✓ Peer-reviewed Brain tissue and pathology Neurology

    Key finding: This study is based on 2 cross-sectional surveys of people aged 75 years or over conducted in central Stockholm: the Kungsholmen Project (KP) (1987-1989, n = 1,700) and the Swedish National study on Aging and Care in Kungsholmen (SNAC-K) (2001-2004, n = 1,575). +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2013-04-17

    Altered expression of diabetes-related genes in Alzheimer's disease brains: the Hisayama study

    ✓ Peer-reviewed Risk factors Cerebral cortex (New York, N.Y. : 1991)

    Key finding: The hippocampi of AD brains showed the most significant alteration in gene expression profile. +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2013-04-16

    Metabolic networks underlying cognitive reserve in prodromal Alzheimer disease: a European Alzheimer disease consortium project

    ✓ Peer-reviewed Brain scans and imaging Journal of nuclear medicine : official publication, Society of Nuclear Medicine

    Key finding: The clusters of significant depression and compensation were further used as volumetric regions of interest (ROIs) in a brain interregional correlation analysis in each prodromal AD subgroup to explore metabolic connectivity. +2 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2013-04-16

    Clathrin adaptor CALM/PICALM is associated with neurofibrillary tangles and is cleaved in Alzheimer's brains

    ✓ Peer-reviewed Genetics Acta neuropathologica

    Key finding: We found that PICALM was abnormally cleaved in AD samples and that the level of the uncleaved 65-75 kDa full-length PICALM species was significantly decreased in AD brains. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2013-04-12

    Modeling disease progression via multi-task learning

    ✓ Peer-reviewed Cognitive tests and assessment NeuroImage

    Key finding: Identifying biomarkers that can track the progress of the disease has recently received increasing attentions in AD research. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2013-04-12

    The effects of hypertension on the cerebral circulation

    ✓ Peer-reviewed How common it is American journal of physiology. Heart and circulatory physiology

    Key finding: Hypertensive artery remodeling results in reduction in the lumen diameter and an increase in the wall-to-lumen ratio in most cerebral arteries; this is linked to reduced blood flow postischemia and increased ischemic damage.

    Full summary, score breakdown and related studies → Original source

  17. 2013-04-11

    Vascular alterations in PDAPP mice after anti-Aβ immunotherapy: Implications for amyloid-related imaging abnormalities

    ✓ Peer-reviewed Treatments Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: These data suggest that vascular leakage events, such as microhemorrhage, may be related to the removal of vascular Aβ. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2013-04-11

    Caregivers' understanding of dementia predicts patients' comfort at death: a prospective observational study

    ✓ Peer-reviewed End-of-life care BMC medicine

    Key finding: Awareness of the terminal nature of dementia may improve patient comfort at the end of life. +1 more finding

    Full summary, score breakdown and related studies → Original source

  19. 2013-04-11

    Patient and Physician Adherence in Hypertension Management

    ✓ Peer-reviewed Health systems and care delivery Journal of Clinical Hypertension

    Key finding: The authors observed that “Our findings showed that nurses provided chronic disease management that was acceptable, feasible and sustainable.” +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2013-04-10

    Bapineuzumab and solanezumab for Alzheimer's disease: is the 'amyloid cascade hypothesis' still alive?

    ✓ Peer-reviewed Treatments Expert opinion on biological therapy

    Key finding: Expert opinion Phase III trials showed that bapineuzumab failed to improve cognitive and functional performances in AD patients, and was associated with a high incidence of amyloid-related imaging abnormalities (ARIA). +3 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2013-04-10

    The case for soluble Aβ oligomers as a drug target in Alzheimer's disease

    ✓ Peer-reviewed Treatments Trends in pharmacological sciences

    Key finding: Accumulating scientific data suggest that soluble Aβ oligomers represent the optimal intervention target within the amyloid manifold.

    Full summary, score breakdown and related studies → Original source

  22. 2013-04-10

    Qualitative evaluation of advanced care planning in early dementia (ACP-ED)

    ✓ Peer-reviewed End-of-life care PloS one

    Key finding: This qualitative evaluation of ACP in early dementia has encouragingly positive results which support the wider application of the intervention in memory services and community mental health teams. +1 more finding

    Full summary, score breakdown and related studies → Original source

  23. 2013-04-10

    Complement receptor 1 coding variant p.Ser1610Thr in Alzheimer's disease and related endophenotypes

    ✓ Peer-reviewed Tau biomarkers Neurobiology of aging

    Key finding: A recent study, however, reported a rare CR1 coding variant p.Ser1610Thr (rs4844609) associated with AD susceptibility, explaining the effect of genome wide association (GWA) top single nucleotide polymorphism rs6656401. +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2013-04-10

    Emerging roles for intersectin (ITSN) in regulating signaling and disease pathways

    ✓ Peer-reviewed Down syndrome and Alzheimer's International journal of molecular sciences

    Key finding: Lower eukaryotes have only one ITSN gene, whereas higher eukaryotes have two ITSN genes. +4 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2013-04-10

    Head-to-head comparison of 11C-PiB and 18F-AZD4694 (NAV4694) for β-amyloid imaging in aging and dementia

    ✓ Peer-reviewed Brain scans and imaging Journal of nuclear medicine : official publication, Society of Nuclear Medicine

    Key finding: (18)F-AZD4694 showed reversible binding kinetics similar to (11)C-PiB, reaching an apparent steady state at 50 min after injection. +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →