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What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 18,126–18,150 of 27,380 studies, newest first · page 726 of 1096.

January 2014 25

  1. 2014-01-07

    Open questions for Alzheimer's disease immunotherapy

    ✓ Peer-reviewed Drug development Alzheimer's research & therapy

    Key finding: Despite disappointing results to date from anti-Aβ immunotherapy therapeutic trials, there is continued hope that such immunotherapies, especially if used in the preclinical stages, could prove to be the first disease-modifying therapies available for AD.

  2. 2014-01-07

    The dual role of astrocyte activation and reactive gliosis

    ✓ Peer-reviewed Brain scans and imaging Neuroscience letters

    Key finding: Activation of astrocytes is associated with changes in the expression of many genes and characteristic morphological hallmarks, and has important functional consequences in situations such as stroke, trauma, epilepsy, Alzheimer's disease (AD), and other neurodegenerative diseases. +1 more finding

  3. 2014-01-06

    Predictors of cognitive impairment in an early stage Parkinson's disease cohort

    ✓ Peer-reviewed Cognitive tests and assessment Movement disorders : official journal of the Movement Disorder Society

    Key finding: Early prediction of future cognitive impairment would help target future interventions. +3 more findings

  4. 2014-01-06

    DJ-1 deficiency triggers microglia sensitivity to dopamine toward a pro-inflammatory phenotype that is attenuated by rasagiline

    ✓ Peer-reviewed TREM2 and immune genetics Journal of neurochemistry

    Key finding: DJ-1 mutations that result in gene deficiency are linked to increased risk of Parkinson's disease (PD). +3 more findings

  5. 2014-01-06

    Cerebral microbleeds: a review of clinical, genetic, and neuroimaging associations

    ✓ Peer-reviewed Caregiving Frontiers in neurology

    Key finding: The presence of microbleeds has been suggested to confer increased risk of incident intracerebral hemorrhage - particularly in the setting of anticoagulation - and of complications of immunotherapy for AD.

  6. 2014-01-04

    Initiating palliative care consults for advanced dementia patients in the emergency department

    ✓ Peer-reviewed End-of-life care Journal of palliative medicine

    Key finding: Preexisting physician attitudes, knowledge, and beliefs prevent emergency physicians from addressing PC needs for AD patients.

  7. 2014-01-04

    Alzheimer disease: epidemiology, diagnostic criteria, risk factors and biomarkers

    ✓ Peer-reviewed Getting a diagnosis Biochemical pharmacology

    Key finding: In the US alone, Alzheimer disease (AD) - the most frequent cause of dementia characterized by a progressive decline in cognitive function in particular the memory domain - causes estimated health-care costs of $ 172 billion per year. +4 more findings

  8. 2014-01-04

    Trazodone improves sleep parameters in Alzheimer disease patients: a randomized, double-blind, and placebo-controlled study

    ✓ Peer-reviewed Treatments The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    Key finding: This study shows significant therapeutic effects of trazodone 50 mg in community-dwelling AD patients with SD. +2 more findings

  9. 2014-01-03

    Early life development in a multiethnic sample and the relation to late life cognition

    ✓ Peer-reviewed Disparities The journals of gerontology. Series B, Psychological sciences and social sciences

    Key finding: These findings demonstrate that early life experiences influence the trajectory of cognitive aging. +4 more findings

  10. 2014-01-02

    Clinicopathologic assessment and imaging of tauopathies in neurodegenerative dementias

    ✓ Peer-reviewed Brain scans and imaging Alzheimer's research & therapy

    Key finding: The spectrum of sporadic frontotemporal lobar degeneration associated with tau pathology includes progressive supranuclear palsy, corticobasal degeneration, and Pick's disease.

  11. 2014-01-02

    Cholesterol as a causative factor in Alzheimer's disease: a debatable hypothesis

    ✓ Peer-reviewed Risk genes beyond APOE Journal of neurochemistry

    Key finding: Some reports, mostly retrospective epidemiological studies, have observed a decreased prevalence of AD in patients taking the cholesterol lowering drugs, statins. +3 more findings

  12. 2014-01-02

    Multiple organ involvement by alpha-synuclein pathology in Lewy body disorders

    ✓ Peer-reviewed Getting a diagnosis Movement disorders : official journal of the Movement Disorder Society

    Key finding: These findings may help in the search of peripheral AS aggregates in vivo for the early diagnosis of PD.

  13. 2014-01-02

    Effect of tai chi on cognitive performance in older adults: systematic review and meta-analysis

    ✓ Peer-reviewed Prevention and risk Journal of the American Geriatrics Society

    Key finding: Tai Chi shows potential to enhance cognitive function in older adults, particularly in the realm of executive functioning and in individuals without significant impairment. +4 more findings

  14. 2014-01-02

    Cerebrospinal fluid neurofilament concentration reflects disease severity in frontotemporal degeneration

    ✓ Peer-reviewed Biomarkers Annals of neurology

    Key finding: CSF NfL is elevated in symptomatic FTD and correlates with disease severity.

  15. 2014 year only

    Targeting synaptic dysfunction in Alzheimer's disease by administering a specific nutrient combination

    ✓ Peer-reviewed Disease mechanisms Journal of Alzheimer's disease : JAD

    Key finding: Memory dysfunction is one key early manifestation in AD and is associated with synapse loss. +1 more finding

  16. 2014 year only

    Cardiovascular risk profile in women and dementia

    ✓ Peer-reviewed Risk factors Journal of Alzheimer's disease : JAD

    Key finding: To explore current evidence on the association between components of the cardiovascular risk profile and dementia risk in women and men, we reviewed all studies reporting the risk of dementia associated with cardiovascular risk factors stratified by gender and found 53 eligible articles out of over 4,000 published since the year 2000. +2 more findings

  17. 2014 year only

    [Sleep problems in dementia]

    ✓ Peer-reviewed Risk factors Rinsho shinkeigaku = Clinical neurology

    Key finding: Age related sleep disturbances and sleep disorders due to the neurodegeneration including REM sleep behavior disorder also increase in dementia. +4 more findings

  18. 2014 year only

    Retinal microvasculature in Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging Journal of Alzheimer's disease : JAD

    Key finding: Recent clinic- and population-based studies have demonstrated a link between retinal vascular changes and dementia, in particular AD, and cerebral small vessel disease.

  19. 2014 year only

    A novel PSEN1 mutation (I238M) associated with early-onset Alzheimer's disease in an African-American woman

    ✓ Peer-reviewed Risk genes beyond APOE Journal of Alzheimer's disease : JAD

    Key finding: Mutations in PSEN1 are the most common cause of autosomal dominant familial Alzheimer's disease (FAD). +3 more findings

  20. 2014 year only

    PSEN1 and PSEN2 gene expression in Alzheimer's disease brain: a new approach

    ✓ Peer-reviewed Risk genes beyond APOE Journal of Alzheimer's disease : JAD

    Key finding: PSEN2 was significantly downregulated in the auditory cortex of AD patients when compared to controls and when compared to other brain regions of the patients.

  21. 2014 year only

    Computerized Neurocognitive Test (CNT) in mild cognitive impairment and Alzheimer's disease

    ✓ Peer-reviewed Cognitive tests and assessment Dementia & neuropsychologia

    Key finding: Currently, computerized batteries are of great value in detecting cognitive impairment. +2 more findings

  22. 2014 year only

    Increased cerebrospinal fluid tau levels in logopenic variant of Alzheimer's disease

    ✓ Peer-reviewed Tau biomarkers Journal of Alzheimer's disease : JAD

    Key finding: p-Tau181 levels were higher in the lvPPA-AD group than in the aMCI-AD group (p < 0.05). +2 more findings

  23. 2014-01-01

    Multivariate data analysis and machine learning in Alzheimer's disease with a focus on structural magnetic resonance imaging

    ✓ Peer-reviewed Digital health tools Journal of Alzheimer's disease : JAD

    Key finding: In particular, these classifiers have been used to discriminate AD patients from healthy control subjects and to predict conversion from mild cognitive impairment to AD. +4 more findings

  24. 2014-01-01

    Deep learning based imaging data completion for improved brain disease diagnosis

    ✓ Peer-reviewed Digital health tools Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention

    Key finding: Combining multi-modality brain data for disease diagnosis commonly leads to improved performance.

  25. 2014-01-01

    Who knows, who cares? Dementia knowledge among nurses, care workers, and family members of people living with dementia

    ✓ Peer-reviewed End-of-life care Journal of palliative care

    Key finding: This paper reports the results of a study that assessed dementia knowledge among these two cohorts using the Dementia Knowledge Assessment Tool; the study surveyed 279 staff members and 164 family members of residents with dementia.

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