Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 12,501–12,525 of 27,380 studies, newest first · page 501 of 1096.
September 2019 22
-
2019-09-04
The CSF p-tau181/Aβ42 Ratio Offers a Good Accuracy “In Vivo” in the Differential Diagnosis of Alzheimer’s Dementia
46/100 ✓ Peer-reviewed Biomarkers Current Alzheimer Research
Key finding: It might constitute a simple, cost-effective and reproducible in vivo proxy of AD suitable to be adopted worldwide not only in daily clinical practice but also in future experimental trials, to avoid the enrolment of misdiagnosed AD patients.
Full summary, score breakdown and related studies → Original source
-
2019-09-04
Hearing loss and Alzheimer's disease: A Review
39/100 ✓ Peer-reviewed Risk factors The international tinnitus journal
Key finding: The mechanisms and causal relationship of this association are still partially unknown, and several theories have been proposed. +4 more findings
Full summary, score breakdown and related studies → Original source
-
2019-09-04
Longitudinal analysis of dementia diagnosis and specialty care among racially diverse Medicare beneficiaries
57/100 ✓ Peer-reviewed Costs and economics Alzheimer's & dementia : the journal of the Alzheimer's Association
Key finding: Ascertainment of etiologic dementia subtype may inform hereditary risk and facilitate financial and care planning. +1 more finding
Full summary, score breakdown and related studies → Original source
-
2019-09-04
Beyond the synucleinopathies: alpha synuclein as a driving force in neurodegenerative comorbidities
41/100 ✓ Peer-reviewed Clinical safety Translational neurodegeneration
Key finding: A wealth of experimental evidence has linked this relatively small but ubiquitously expressed protein to a plethora of cytopathologic mechanisms and suggests that aSyn may be capable of seeding the progressive spread of synucleinopathy throughout the brain. +1 more finding
Full summary, score breakdown and related studies → Original source
-
2019-09-04
Can Hearing Aids Delay Time to Diagnosis of Dementia, Depression, or Falls in Older Adults?
69/100 ✓ Peer-reviewed Clinical safety Journal of the American Geriatrics Society
Key finding: Use of HAs is associated with delayed diagnosis of AD, dementia, depression, anxiety, and injurious falls among older adults with HL. +1 more finding
Full summary, score breakdown and related studies → Original source
-
2019-09-04
Neuroinflammatory Processes, A1 Astrocyte Activation and Protein Aggregation in the Retina of Alzheimer's Disease Patients, Possible Biomarkers for Early Diagnosis
47/100 ✓ Peer-reviewed Inflammation and the immune system Frontiers in neuroscience
Key finding: It is commonly thought that the lack of early diagnostic criteria is among the main causes of pharmacological therapy and clinical trials failure; therefore, the actual challenge is to define new biomarkers and non-invasive technologies to measure neuropathological changes in vivo at pre-symptomatic stages. +3 more findings
Full summary, score breakdown and related studies → Original source
-
2019-09-04
Impact of Project ECHO Models of Medical Tele-Education: a Systematic Review
61/100 ✓ Peer-reviewed Disparities Journal of general internal medicine
Key finding: The number of studies examining ECHO and ECHO-like models of medical tele-education has been modest compared with the scope and scale of implementation throughout the USA and internationally. +2 more findings
Full summary, score breakdown and related studies → Original source
-
2019-09-04
Dementia in China: epidemiology, clinical management, and research advances
59/100 ✓ Peer-reviewed Getting a diagnosis The Lancet. Neurology
Key finding: The number of clinical trials of Chinese and western medicines has substantially increased as a result of progress in research on new antidementia drugs but international multicentre studies are few in number.
Full summary, score breakdown and related studies → Original source
-
2019-09-03
Mobile applications to detect hearing impairment: opportunities and challenges
41/100 ✓ Peer-reviewed Cognitive tests and assessment Bulletin of the World Health Organization
Hearing loss affects close to 1.3 billion people and is a growing global health concern as the fourth leading contributor to years lived with disability. 1 The global economic cost associated with hearing loss is estimated at 750 billion United States dollars (US$) annually.2 However, hearing loss has limited public health support, especially in low-and middle-income countries, where incidence is high and resources often scarce and unequally distributed.
Full summary, score breakdown and related studies → Original source
-
2019-09-03
Educational Program for Promoting Collaboration Between Community Care Professionals and Convenience Stores
39/100 ✓ Peer-reviewed Risk factors Journal of Applied Gerontology
Key finding: After the program, the total score for attitudes toward dementia ( p = .010) improved significantly among the convenience store staff. +2 more findings
Full summary, score breakdown and related studies → Original source
-
2019-09-02
TREM2 regulates obesity-induced insulin resistance via adipose tissue remodeling in mice of high-fat feeding
43/100 ✓ Peer-reviewed TREM2 and immune genetics Journal of translational medicine
Key finding: Adipose tissue remodeling plays a significant role in obesity-induced insulin resistance. +3 more findings
Full summary, score breakdown and related studies → Original source
-
2019-09 month only
[Anti-tau therapies-what can be expected?]
39/100 ✓ Peer-reviewed Drug development Der Nervenarzt
Key finding: Alzheimer's disease is histopathologically characterized by aggregation of two proteins, namely amyloid-beta peptide and tau protein. +2 more findings
Full summary, score breakdown and related studies → Original source
-
2019-09-01
Sex differences in the genetic predictors of Alzheimer's pathology
82/100 ✓ Peer-reviewed Genetics Brain : a journal of neurology
Key finding: In follow-up analyses, rs34331204 was also associated with hippocampal volume, executive function, and age-at-onset only among males. +1 more finding
Full summary, score breakdown and related studies → Original source
-
2019-09-01
What do relatives value most in end-of-life care for people with dementia?
45/100 ✓ Peer-reviewed End-of-life care International journal of palliative nursing
Key finding: Experiences translated into four themes: acknowledging human dignity; being recognised as an important caregiver; (not) talking about death and dying and making decisions together. +4 more findings
Full summary, score breakdown and related studies → Original source
-
2019-09-01
159 Geographic Accessibility and Capacity of Day Care Services for People with Dementia
34/100 ✓ Peer-reviewed Risk factors Age and Ageing
Key finding: Day care has a place in the menu of service for people with dementia living in the community.
Full summary, score breakdown and related studies → Original source
-
2019-09-01
[New biomarkers for Alzheimer's disease in cerebrospinal fluid and blood]
31/100 ✓ Peer-reviewed Tau biomarkers Der Nervenarzt
Key finding: Several studies have clearly shown that determination of the amyloid beta 42 to amyloid beta 40 peptide ratio is superior to the interpretation of amyloid beta 42 alone and should be implemented in the clinical work-up; however, in recent years different studies have presented many other innovative CSF and blood-based biomarkers. +2 more findings
Full summary, score breakdown and related studies → Original source
-
2019-09-01
Improving diagnostic accuracy of multiple system atrophy: a clinicopathological study
58/100 ✓ Peer-reviewed Digital health tools Brain : a journal of neurology
Key finding: Multiple logistic regression analysis revealed increased likelihood of multiple system atrophy versus Lewy body disease and progressive supranuclear palsy if a patient developed orthostatic hypotension or urinary incontinence with the requirement for urinary catheters [multiple system atrophy versus Lewy body disease: odds ratio (OR): 2.0, 95% confidence interval (CI): 1.1-3.7, P = 0.021; multiple system atrophy versus progressive supranuclear palsy: OR: 11.2, 95% CI: 3.2-39.2, P < 0.01]. +1 more finding
Full summary, score breakdown and related studies → Original source
-
2019-09-01
The Self-Care Needs and Behaviors of Dementia Informal Caregivers: A Systematic Review
58/100 ✓ Peer-reviewed Disparities The Gerontologist
Key finding: Three themes emerged from 29 included studies: self-care needs and behaviors of ICGs, barriers to performing self-care, and enablers of self-care.
Full summary, score breakdown and related studies → Original source
-
2019-09-01
Influence of Positive Aspects of Dementia Caregiving on Caregivers' Well-Being: A Systematic Review
60/100 ✓ Peer-reviewed Caregiving The Gerontologist
Key finding: Fifty-three studies were included in the narrative synthesis. +4 more findings
Full summary, score breakdown and related studies → Original source
-
2019-09-01
Association of Midlife Hearing Impairment With Late-Life Temporal Lobe Volume Loss
67/100 ✓ Peer-reviewed Brain scans and imaging JAMA otolaryngology-- head & neck surgery
Key finding: The findings suggest that midlife HI is a risk factor for temporal lobe volume loss. +4 more findings
Full summary, score breakdown and related studies → Original source
-
2019-09-01
Performance of Fully Automated Plasma Assays as Screening Tests for Alzheimer Disease-Related β-Amyloid Status
71/100 ✓ Peer-reviewed Biomarkers JAMA neurology
Key finding: The mean (SD) age of the 842 participants in cohort 1 was 72 (5.6) years, with a range of 59 to 88 years, and 446 (52.5%) were female. +2 more findings
Full summary, score breakdown and related studies → Original source
-
2019-09-01
Diagnostic Value of Cerebrospinal Fluid Neurofilament Light Protein in Neurology: A Systematic Review and Meta-analysis
69/100 ✓ Peer-reviewed Biomarkers JAMA neurology
Key finding: These data support the use of cNfL as a biomarker of neuroaxonal damage and indicate that age-specific and sex-specific (and in some cases disease-specific) reference values may be needed. +3 more findings
Full summary, score breakdown and related studies → Original source
August 2019 3
-
2019-08-31
Demands for Development of Taurine-Containing Home Meal Replacement for Prevention of Dementia According to Age
36/100 ✓ Peer-reviewed Risk factors Advances in experimental medicine and biology
Key finding: The level of need for EF-HMR was significantly higher in 40-49 years and 50-64 years groups compared to the elderly group (p < 0.001). +3 more findings
Full summary, score breakdown and related studies → Original source
-
2019-08-30
Omega-3 Fatty Acids and Neurodegenerative Diseases: New Evidence in Clinical Trials
68/100 ✓ Peer-reviewed Prevention and risk International journal of molecular sciences
Key finding: A nutritional approach could be a promising strategy to prevent or slow the progression of neurodegenerative diseases such as Parkinson's and Alzheimer's disease, since there is no effective therapy for these diseases so far. +3 more findings
Full summary, score breakdown and related studies → Original source
-
2019-08-30
Transfer of a healthy microbiota reduces amyloid and tau pathology in an Alzheimer's disease animal model
38/100 ✓ Peer-reviewed Disease mechanisms Gut
Key finding: These results indicate that microbiota-mediated intestinal and systemic immune aberrations contribute to the pathogenesis of AD in ADLP APT mice, providing new insights into the relationship between the gut (colonic gene expression, gut permeability), blood (blood immune cell population) and brain (pathology) axis and AD (memory deficits). +1 more finding
Full summary, score breakdown and related studies → Original source
Browse the library by subject, with the full score breakdown →