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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 18,776–18,800 of 27,380 studies, newest first · page 752 of 1096.

April 2013 10

  1. 2013-04-01

    MicroRNA-144 is regulated by activator protein-1 (AP-1) and decreases expression of Alzheimer disease-related a disintegrin and metalloprotease 10 (ADAM10)

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: MicroRNA (miR) dysregulation is found in Alzheimer disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2013-04-01

    Regulation of TREM2 expression by an NF-кB-sensitive miRNA-34a

    ✓ Peer-reviewed Risk genes beyond APOE Neuroreport

    Key finding: In this study, we provide evidence that TREM2 is downregulated in samples of sporadic Alzheimer hippocampal CA1 compared with age-matched controls. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2013-04-01

    A transgenic Alzheimer rat with plaques, tau pathology, behavioral impairment, oligomeric aβ, and frank neuronal loss

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: The "amyloid cascade hypothesis" posits that cerebral amyloid sets neurotoxic events into motion that precipitate Alzheimer dementia (Hardy and Allsop, 1991). +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2013-04-01

    Clinical diagnostic criteria and classification controversies in frontotemporal lobar degeneration

    ✓ Peer-reviewed Digital health tools International review of psychiatry (Abingdon, England)

    Key finding: Recently, revised diagnostic criteria have been proposed for the behavioural and progressive aphasia syndromes associated with frontotemporal degeneration.

    Full summary, score breakdown and related studies → Original source

  5. 2013-04-01

    The epidemiology of frontotemporal dementia

    ✓ Peer-reviewed Disparities International review of psychiatry (Abingdon, England)

    Key finding: FTD shows poor life expectancy but with survival comparable to that of Alzheimer's disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2013-04-01

    Monetary costs of dementia in the United States

    ✓ Peer-reviewed Getting a diagnosis The New England journal of medicine

    Key finding: Dementia represents a substantial financial burden on society, one that is similar to the financial burden of heart disease and cancer. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2013-04-01

    White matter hyperintensities and cerebral amyloidosis: necessary and sufficient for clinical expression of Alzheimer disease?

    ✓ Peer-reviewed Prevention and risk JAMA neurology

    Key finding: White matter hyperintensities contribute to the presentation of AD and, in the context of significant amyloid deposition, may provide a second hit necessary for the clinical manifestation of the disease. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2013-04-01

    Predicting cognitive decline: a dementia risk score vs. the Framingham vascular risk scores

    ✓ Peer-reviewed Prevention and risk Neurology

    Key finding: The CAIDE dementia and Framingham risk scores predict cognitive decline in late middle age but the Framingham risk scores may have an advantage over the dementia risk score for use in primary prevention for assessing risk of cognitive decline and targeting of modifiable risk factors. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2013-04-01

    Cerebrovascular effects of apolipoprotein E: implications for Alzheimer disease

    ✓ Peer-reviewed Genetics JAMA neurology

    Key finding: APOE4 is a major genetic risk factor for Alzheimer disease and is associated with dementia in Down syndrome and poor neurological outcome after traumatic brain injury, cerebral hemorrhage, and other neuropathological disorders.

    Full summary, score breakdown and related studies → Original source

  10. 2013-04-01

    Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans

    ✓ Peer-reviewed Genetics JAMA

    Key finding: Genome-wide significance in fully adjusted models (sex, age, APOE genotype, population stratification) was observed for a SNP in ABCA7 (rs115550680, allele = G; frequency, 0.09 cases and 0.06 controls; odds ratio [OR], 1.79 [95% CI, 1.47-2.12]; P = 2.2 × 10(-9)), which is in linkage disequilibrium with SNPs previously associated with Alzheimer disease in Europeans (0.8 Conclusions and relevance In this meta-analysis of data from African American participants, Alzheimer disease was significantly associated with variants in ABCA7 and with other genes that have been associated with Alzheimer disease in individuals of European ancestry. +3 more findings

    Full summary, score breakdown and related studies → Original source

March 2013 15

  1. 2013-03-28

    Prodromal autonomic symptoms and signs in Parkinson's disease and dementia with Lewy bodies

    ✓ Peer-reviewed Brain scans and imaging Movement disorders : official journal of the Movement Disorder Society

    Key finding: Pathologic staging systems suggest that autonomic dysfunction may be an early manifestation of Parkinson's disease and dementia with Lewy bodies. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2013-03-28

    Magnetic resonance imaging evidence for presymptomatic change in thalamus and caudate in familial Alzheimer's disease

    ✓ Peer-reviewed Hippocampus size on brain scans Brain : a journal of neurology

    Key finding: Amyloid imaging studies of presymptomatic familial Alzheimer's disease have revealed the striatum and thalamus to be the earliest sites of amyloid deposition. +2 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2013-03-28

    Vitamin D effects on musculoskeletal health, immunity, autoimmunity, cardiovascular disease, cancer, fertility, pregnancy, dementia and mortality-a review of recent evidence

    ✓ Peer-reviewed Risk factors Autoimmunity reviews

    Key finding: Adequate vitamin D supplementation and sensible sunlight exposure to reach optimal vitamin D status are among the front line factors of prophylaxis for the spectrum of disorders. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2013-03-27

    Factors predicting reversion from mild cognitive impairment to normal cognitive functioning: a population-based study

    ✓ Peer-reviewed Prevention and risk PloS one

    Key finding: There were 66 reverters to normal cognition and 157 non-reverters (stable MCI). +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2013-03-25

    Genome-wide association study of the rate of cognitive decline in Alzheimer's disease

    ✓ Peer-reviewed Genetics Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: SPON1 has not been previously associated with AD risk, but is plausibly related because the gene product binds to the amyloid precursor protein and inhibits its cleavage by β-secretase. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2013-03-25

    The prevalence and incidence of dementia with Lewy bodies: a systematic review of population and clinical studies

    ✓ Peer-reviewed Getting a diagnosis Psychological medicine

    Key finding: DLB currently accounts for around one in 25 dementia cases diagnosed in the community and one in 13 cases in secondary care. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2013-03-24

    Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-β

    ✓ Peer-reviewed Disease mechanisms Nature neuroscience

    Key finding: Thus, transient increases in neuronal DSBs occur as a result of physiological brain activity, and Aβ exacerbates DNA damage, most likely by eliciting synaptic dysfunction.

    Full summary, score breakdown and related studies → Original source

  8. 2013-03-24

    mTOR regulates tau phosphorylation and degradation: implications for Alzheimer's disease and other tauopathies

    ✓ Peer-reviewed Risk factors Aging cell

    Key finding: Age is a major risk factor for all tauopathies, suggesting that molecular changes contributing to the aging process may facilitate tau accumulation and represent common mechanisms across different tauopathies. +1 more finding

    Full summary, score breakdown and related studies → Original source

  9. 2013-03-23

    Prevalence and associated factors of dysphagia in nursing home residents

    ✓ Peer-reviewed Clinical safety Geriatric nursing (New York, N.Y.)

    Key finding: The aims of this study were to evaluate the prevalence of dysphagia in nursing home residents in South Korea and to identify factors associated with dysphagia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2013-03-22

    Dying with dementia: symptom burden, quality of care, and place of death

    ✓ Peer-reviewed End-of-life care Deutsches Arzteblatt international

    Key finding: These data indicate the high symptom burden of persons with dementia in Germany at the end of their lives.

    Full summary, score breakdown and related studies → Original source

  11. 2013-03-22

    Exploring the effect of companion robots on emotional expression in older adults with dementia: a pilot randomized controlled trial

    ✓ Peer-reviewed Clinical safety Journal of gerontological nursing

    Key finding: PARO had a moderate to large positive influence on participants' quality of life compared to the reading group. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2013-03-22

    The intersection of amyloid β and tau in glutamatergic synaptic dysfunction and collapse in Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms Ageing research reviews

    Key finding: More recent data indicate that pathological forms of tau protein, which accumulate in neurofibrillary tangles in the AD brain, also cause synaptic dysfunction and loss.

    Full summary, score breakdown and related studies → Original source

  13. 2013-03-22

    Survival in dementia and predictors of mortality: a review

    ✓ Peer-reviewed Getting a diagnosis International journal of geriatric psychiatry

    Key finding: Substantial heterogeneity in the design of included studies limits the ability to prognosticate for individual patients. +2 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2013-03-21

    Nursing home residents dying with dementia in Flanders, Belgium: a nationwide postmortem study on clinical characteristics and quality of dying

    ✓ Peer-reviewed End-of-life care Journal of the American Medical Directors Association

    Key finding: Regardless of the dementia stage, many nursing home residents develop serious clinical complications and symptoms in the last phase of life, posing major challenges to the provision of optimum end-of-life care. +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2013-03-19

    The triple challenges associated with age-related comorbidities in Down syndrome

    ✓ Peer-reviewed Risk factors Journal of intellectual disability research : JIDR

    Key finding: Further detailed investigations into the development and treatment of comorbidities across the lifespan are needed for a successful longitudinal approach to healthcare in people with Down syndrome. +1 more finding

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →