alzhub.org
Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 18,176–18,200 of 27,380 studies, newest first · page 728 of 1096.

January 2014 25

  1. 2014-01-01

    Mortality risk after dementia diagnosis by dementia type and underlying factors: a cohort of 15,209 patients based on the Swedish Dementia Registry

    ✓ Peer-reviewed Cognitive tests and assessment Journal of Alzheimer's disease : JAD

    Key finding: Knowledge on survival in dementia is crucial for patients and public health planning. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2014-01-01

    Post-stroke cognitive impairment: high prevalence and determining factors in a cohort of mild stroke

    ✓ Peer-reviewed Cognitive tests and assessment Journal of Alzheimer's disease : JAD

    Key finding: Because of the aging population and a rise in the number of stroke survivors, the prevalence of post-stroke cognitive impairment (PSCI) is increasing. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2014-01-01

    Regional cortical thinning and cerebrospinal biomarkers predict worsening daily functioning across the Alzheimer's disease spectrum

    ✓ Peer-reviewed Tau biomarkers Journal of Alzheimer's disease : JAD

    Key finding: Impairment in instrumental activities of daily living (IADL) heralds the transition from mild cognitive impairment (MCI) to dementia and is a major source of burden for both the patient and caregiver. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2014-01-01

    Relationship between β-Secretase, inflammation and core cerebrospinal fluid biomarkers for Alzheimer's disease

    ✓ Peer-reviewed Tau biomarkers Journal of Alzheimer's disease : JAD

    Key finding: Biomarkers in the cerebrospinal fluid (CSF) can track specific pathophysiological pathways underlying Alzheimer's disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2014-01-01

    Lack of genetic association between TREM2 and late-onset Alzheimer's disease in a Japanese population

    ✓ Peer-reviewed TREM2 and immune genetics Journal of Alzheimer's disease : JAD

    Key finding: We here conducted a replication study using a well-characterized Japanese sample set, comprising 2,190 late-onset AD (LOAD) cases and 2,498 controls. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2014-01-01

    Increased expression of TREM2 in peripheral blood of Alzheimer's disease patients

    ✓ Peer-reviewed TREM2 and immune genetics Journal of Alzheimer's disease : JAD

    Key finding: Here, we evaluated TREM2 mRNA and protein expressions in peripheral blood from AD patients and healthy controls. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2014-01-01

    Genetics of Alzheimer's disease

    ✓ Peer-reviewed TREM2 and immune genetics Advances in genetics

    Key finding: Despite intensive research efforts, current treatments have only marginal symptomatic benefits and there are no effective disease-modifying or preventive interventions. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2014-01-01

    Alzheimer´s disease and oxidative stress: a review

    ✓ Peer-reviewed Risk genes beyond APOE Current medicinal chemistry

    Key finding: The predominant cognitive impairment is currently treated using cognitive enhancers like cholinesterase inhibitors. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2014-01-01

    Depression in mild cognitive impairment is associated with progression to Alzheimer's disease: a longitudinal study

    ✓ Peer-reviewed Mild cognitive impairment Journal of Alzheimer's disease : JAD

    Key finding: Depressive symptoms in MCI appear to be predictors for progression to AD. +2 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2014-01-01

    Body mass index, weight change, and clinical progression in mild cognitive impairment and Alzheimer disease

    ✓ Peer-reviewed Mild cognitive impairment Alzheimer disease and associated disorders

    Key finding: We assessed whether body mass index (BMI) and 1-year weight change (WC) are associated with clinical progression in amnestic mild cognitive impairment (aMCI) and early-stage AD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2014-01-01

    Neuropsychological predictors of conversion from mild cognitive impairment to Alzheimer's disease

    ✓ Peer-reviewed Mild cognitive impairment Journal of Alzheimer's disease : JAD

    Key finding: Although subjects with MCI have an increased risk of progressing to dementia, most remain stable or return to normality. +2 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2014-01-01

    Cognitive changes preceding clinical symptom onset of mild cognitive impairment and relationship to ApoE genotype

    ✓ Peer-reviewed Mild cognitive impairment Current Alzheimer research

    Key finding: Cognitive changes in normal individuals who will subsequently decline may be observed at least 6.5 years prior to symptom onset.

    Full summary, score breakdown and related studies → Original source

  13. 2014-01-01

    Neuropsychological decline in schizophrenia from the premorbid to the postonset period: evidence from a population-representative longitudinal study

    ✓ Peer-reviewed Mild cognitive impairment The American journal of psychiatry

    Key finding: There is substantial neuropsychological decline in schizophrenia from the premorbid to the postonset period, but the extent and developmental progression of decline varies across mental functions. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2014-01-01

    Neuropsychological criteria for mild cognitive impairment improves diagnostic precision, biomarker associations, and progression rates

    ✓ Peer-reviewed Mild cognitive impairment Journal of Alzheimer's disease : JAD

    Key finding: We compared two methods of diagnosing mild cognitive impairment (MCI): conventional Petersen/Winblad criteria as operationalized by the Alzheimer's Disease Neuroimaging Initiative (ADNI) and an actuarial neuropsychological method put forward by Jak and Bondi designed to balance sensitivity and reliability. 1,150 ADNI participants were diagnosed at baseline as cognitively normal (CN) or MCI via ADNI criteria (MCI: n = 846; CN: n = 304) or Jak/Bondi criteria (MCI: n = 401; CN: n = 749), and the two MCI samples were submitted to cluster and discriminant function analyses. +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2014-01-01

    Synaptophysin and synaptojanin-1 in Down syndrome are differentially affected by Alzheimer's disease

    ✓ Peer-reviewed Down syndrome and Alzheimer's Journal of Alzheimer's disease : JAD

    Key finding: SYN was significantly lower in DSAD compared with DS alone and similar to sporadic AD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2014-01-01

    Long-term metformin usage and cognitive function among older adults with diabetes

    ✓ Peer-reviewed Risk factors Journal of Alzheimer's disease : JAD

    Key finding: Evidence strongly supports the important role of insulin resistance in cognitive decline and dementia and suggests that insulin sensitizers may protect against cognitive decline in diabetic and pre-diabetic individuals. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2014-01-01

    eButton: A Wearable Computer for Health Monitoring and Personal Assistance

    ✓ Peer-reviewed Digital health tools Proceedings. Design Automation Conference

    Key finding: Diagnosis and treatment of diseases are still initiated by occurrences of symptoms, and technologies and devices that emphasize on disease prevention and early detection outside hospitals are under-developed. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2014-01-01

    Parkinson's disease: a review

    ✓ Peer-reviewed How common it is Frontiers in bioscience (Scholar edition)

    Key finding: Resulting from a pathophysiologic loss or degeneration of dopaminergic neurons in the substantia nigra of the midbrain and the development of neuronal Lewy Bodies, idiopathic Parkinson's Disease is associated with risk factors including aging, family history, pesticide exposure and environmental chemicals (e.g., synthetic heroin use). +2 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2014-01-01

    Factors associated with initiation of advance care planning in dementia: a systematic review

    ✓ Peer-reviewed Disparities Journal of Alzheimer's disease : JAD

    Key finding: Professional caregivers may initiate ACP early if strategies carefully consider timing and family and patient receptiveness or reluctance, and are family and patient-centered. +1 more finding

    Full summary, score breakdown and related studies → Original source

  20. 2014-01-01

    Optimizing patient care and research: the Amsterdam Dementia Cohort

    ✓ Peer-reviewed Getting a diagnosis Journal of Alzheimer's disease : JAD

    Key finding: By answering research questions closely related to clinical practice, the results of our research can be looped back to improve clinical work-up for our patients.

    Full summary, score breakdown and related studies → Original source

  21. 2014-01-01

    Modifiable lifestyle factors in dementia: a systematic review of longitudinal observational cohort studies

    ✓ Peer-reviewed Prevention and risk Journal of Alzheimer's disease : JAD

    Key finding: Broad consensus emerged on the protective role against dementia of leisure activities. +2 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2014-01-01

    Heart diseases and long-term risk of dementia and Alzheimer's disease: a population-based CAIDE study

    ✓ Peer-reviewed Prevention and risk Journal of Alzheimer's disease : JAD

    Key finding: Late-life heart diseases increase the subsequent risk of dementia and AD.

    Full summary, score breakdown and related studies → Original source

  23. 2014-01-01

    Serum brain-derived neurotrophic factor and the risk for dementia: the Framingham Heart Study

    ✓ Peer-reviewed Prevention and risk JAMA neurology

    Key finding: Some prior studies showed lower circulating BDNF in persons with Alzheimer disease (AD) compared with control participants; however, it remains uncertain whether reduced levels precede dementia onset. +4 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2014-01-01

    Association of mediterranean diet with mild cognitive impairment and Alzheimer's disease: a systematic review and meta-analysis

    ✓ Peer-reviewed Prevention and risk Journal of Alzheimer's disease : JAD

    Key finding: Out of the 664 studies screened, five studies met eligibility criteria. +2 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2014-01-01

    Is sertraline treatment or depression remission in depressed Alzheimer patients associated with improved caregiver well being? Depression in Alzheimer's Disease Study 2

    ✓ Peer-reviewed Treatments The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    Key finding: Patient treatment with sertraline was not associated with significantly greater reductions in caregiver distress than placebo treatment. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →