alzhub.org
Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 24,426–24,450 of 27,380 studies, newest first · page 978 of 1096.

July 2003 25

  1. 2003-07-08

    Subacute meningoencephalitis in a subset of patients with AD after Aβ42 immunization

    ✓ Peer-reviewed Clinical safety Neurology

    Postvaccination meningoencephalitis occurred without clear relation to serum anti-Abeta42 antibody titers.

    Full summary, score breakdown and related studies → Original source

  2. 2003-07-02

    Chronic stress and age-related increases in the proinflammatory cytokine IL-6

    ✓ Peer-reviewed Risk factors Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Overproduction of IL-6, a proinflammatory cytokine, is associated with a spectrum of age-related conditions including cardiovascular disease, osteoporosis, arthritis, type 2 diabetes, certain cancers, periodontal disease, frailty, and functional decline. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2003-07-01

    App gene dosage modulates endosomal abnormalities of Alzheimer's disease in a segmental trisomy 16 mouse model of down syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: These results identify an essential role for App gene triplication in causing AD-related endosomal abnormalities and further establish the pathogenic significance of endosomal dysfunction in AD.

    Full summary, score breakdown and related studies → Original source

  4. 2003-07-01

    Clinical and organizational factors associated with feeding tube use among nursing home residents with advanced cognitive impairment

    ✓ Peer-reviewed Health systems and care delivery JAMA

    Key finding: More than one third of severely cognitively impaired residents in US nursing homes have feeding tubes. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2003-07-01

    Age but not diagnosis is the main predictor of plasma amyloid beta-protein levels

    ✓ Peer-reviewed Drug development Archives of neurology

    Key finding: Plasma Abeta measures increase with age, but, in contrast to reports on familial AD, plasma Abeta measures were neither sensitive nor specific for the clinical diagnosis of mild cognitive impairment or sporadic AD. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2003-07-01

    Statin-associated memory loss: analysis of 60 case reports and review of the literature

    ✓ Peer-reviewed Drug development Pharmacotherapy

    Key finding: Current literature is conflicting with regard to the effects of statins on memory loss. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2003-07-01

    Melatonin for treatment of REM sleep behavior disorder in neurologic disorders: results in 14 patients

    ✓ Peer-reviewed Brain scans and imaging Sleep medicine

    Key finding: Fourteen patients were commenced on melatonin over the specified time period (13 male, median RBD onset age 56 years, range 20-77 years). +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2003-07-01

    Parkinson's disease is associated with hippocampal atrophy

    ✓ Peer-reviewed Hippocampus size on brain scans Movement disorders : official journal of the Movement Disorder Society

    Key finding: Patients with Parkinson's disease (PD) may have hippocampal atrophy compared with controls. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2003-07-01

    Dementia after delirium in patients with femoral neck fractures

    ✓ Peer-reviewed Clinical safety Journal of the American Geriatrics Society

    Key finding: Delirium in nondemented femoral neck fracture patients is associated with the development of dementia and a higher mortality rate. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2003-07-01

    RAGE mediates amyloid-beta peptide transport across the blood-brain barrier and accumulation in brain

    ✓ Peer-reviewed Disease mechanisms Nature medicine

    Key finding: Systemic Abeta infusion and studies in genetically manipulated mice show that Abeta interaction with receptor for advanced glycation end products (RAGE)-bearing cells in the vessel wall results in transport of Abeta across the blood-brain barrier (BBB) and expression of proinflammatory cytokines and endothelin-1 (ET-1), the latter mediating Abeta-induced vasoconstriction. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2003-07-01

    Consumption of Fish and n-3 Fatty Acids and Risk of Incident Alzheimer Disease

    ✓ Peer-reviewed Risk factors Archives of Neurology

    Dietary intake of n-3 fatty acids and weekly consumption of fish may reduce the risk of incident Alzheimer disease.

    Full summary, score breakdown and related studies → Original source

  12. 2003-07-01

    Pattern Recognition by TREM-2: Binding of Anionic Ligands

    ✓ Peer-reviewed TREM2 and immune genetics The Journal of Immunology

    We recently described the cloning of murine triggering receptor expressed by myeloid cells (TREM) 2, a single Ig domain DNAX adaptor protein 12-associated receptor expressed by cells of the myeloid lineage.

    Full summary, score breakdown and related studies → Original source

  13. 2003-07-01

    Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles

    ✓ Peer-reviewed Laboratory science Neuron

    Key finding: 3xTg-AD mice progressively develop plaques and tangles. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2003-07-01

    Melissa officinalis extract in the treatment of patients with mild to moderate Alzheimer's disease: a double blind, randomised, placebo controlled trial

    ✓ Peer-reviewed Cognitive tests and assessment Journal of neurology, neurosurgery, and psychiatry

    Key finding: A four month, parallel group, placebo controlled trial undertaken in three centres in Tehran, Iran. +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2003-07-01

    DNA synthesis and neuronal apoptosis caused by familial Alzheimer disease mutants of the amyloid precursor protein are mediated by the p21 activated kinase PAK3

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: However, the signaling mechanisms that mediate these events have not been defined. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2003-07-01

    The amyloid precursor protein and its regulatory protein, FE65, in growth cones and synapses in vitro and in vivo

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: Much less is known about its binding partner FE65. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2003-07-01

    Relation between apolipoprotein E genotype, hepatitis B virus status, and thyroid status in a sample of older persons with Down syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's American journal of medical genetics. Part A

    Key finding: In females, there was an ApoE allele effect on thyroid status (P < or = 0.01), E2 being negatively (P < or = 0.01) and E4 being positively (P < or = 0.05) associated with "hypothyroidism".

    Full summary, score breakdown and related studies → Original source

  18. 2003-07-01

    Homocysteine and Alzheimer's disease

    ✓ Peer-reviewed Risk factors The Lancet. Neurology

    Key finding: Epidemiological studies found associations between hyperhomocysteinaemia and both histologically confirmed AD and disease progression and revealed that dementia in AD was associated with evidence of brain infarcts on autopsy. +1 more finding

    Full summary, score breakdown and related studies → Original source

  19. 2003-07-01

    Prevalence of dementia in three ethnic groups: the South Florida program on aging and health

    ✓ Peer-reviewed Disparities Annals of epidemiology

    Key finding: Age (p = 0.001), family history of AD (p = 0.02) and African American (p = 0.0001) or Cuban (p = 0.006) ethnic group were directly and independently associated with the prevalence of AD.

    Full summary, score breakdown and related studies → Original source

  20. 2003-07-01

    Donepezil is associated with delayed nursing home placement in patients with Alzheimer's disease

    ✓ Peer-reviewed Treatments Journal of the American Geriatrics Society

    Key finding: Use of donepezil by AD patients resulted in significant delays in NHP. +1 more finding

    Full summary, score breakdown and related studies → Original source

  21. 2003-07-01

    An 18-year follow-up of overweight and risk of Alzheimer disease

    ✓ Peer-reviewed Prevention and risk Archives of internal medicine

    Key finding: During the 18-year follow-up (4184.8 risk-years), 93 participants were diagnosed as having dementia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  22. 2003-07-01

    Psychosis of Alzheimer disease: validity of the construct and response to risperidone

    ✓ Peer-reviewed Treatments The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    Key finding: The construct of psychosis of dementia was validated, and the severity of both psychosis and aggressiveness was reduced with risperidone treatment in a robust and dose-related way, with a continuing response over the 12-week trial period.

    Full summary, score breakdown and related studies → Original source

  23. 2003-07-01

    Treating depression in Alzheimer disease: efficacy and safety of sertraline therapy, and the benefits of depression reduction: the DIADS

    ✓ Peer-reviewed Treatments Archives of general psychiatry

    Key finding: In the sertraline-treated group 9 patients (38%) were full responders and 11 (46%) were partial responders compared with 3 (20%) and 4 (15%), respectively, in the placebo-treated group (P =.007). +2 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2003-07-01

    Mid-life smoking and late-life dementia: the Honolulu-Asia Aging Study

    ✓ Peer-reviewed Genetics Neurobiology of aging

    Key finding: Very heavy smoking was not associated with AD (OR=1.08; 95% CI=0.43-2.63). +1 more finding

    Full summary, score breakdown and related studies → Original source

  25. 2003-07-01

    Mild hypercholesterolemia is an early risk factor for the development of Alzheimer amyloid pathology

    ✓ Peer-reviewed Genetics Neurology

    Key finding: Serum hypercholesterolemia may be an early risk factor for the development of AD amyloid pathology. +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →