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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 17,551–17,575 of 27,380 studies, newest first · page 703 of 1096.

October 2014 25

  1. 2014-10-18

    Cognitive health and Mediterranean diet: just diet or lifestyle pattern?

    ✓ Peer-reviewed Prevention trials Ageing research reviews

    Key finding: It also evaluates evidence on behaviors related to the Mediterranean way of living, that have been shown to be associated with cognition, namely social interaction, participation in leisure activities, including physical activities, and sleep quality.

    Full summary, score breakdown and related studies → Original source

  2. 2014-10-18

    Abnormal retinal nerve fiber layer thickness and macula lutea in patients with mild cognitive impairment and Alzheimer's disease

    ✓ Peer-reviewed Cognitive tests and assessment Archives of gerontology and geriatrics

    Key finding: We investigated possible abnormalities in the retinal nerve fiber layer (RNFL) and macula lutea of patients diagnosed with Alzheimer's disease (AD) and mild cognitive impairment (MCI) and tested for any correlation with the severity of dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2014-10-16

    The main cost drivers in dementia: a systematic review

    ✓ Peer-reviewed Caregiving International journal of geriatric psychiatry

    Key finding: The results of this review highlight the significant economic burden of dementia for patients, families and healthcare systems and thus are important for future health policy planning. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2014-10-16

    Myeloid microvesicles in cerebrospinal fluid are associated with myelin damage and neuronal loss in mild cognitive impairment and Alzheimer disease

    ✓ Peer-reviewed Brain scans and imaging Annals of neurology

    Key finding: Microglial MVs are neurotoxic and myelinotoxic in the presence of Aβ1-42 . +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2014-10-15

    Clinical and neuroimaging characterization of Chinese dementia patients with PSEN1 and PSEN2 mutations

    ✓ Peer-reviewed Risk genes beyond APOE Dementia and geriatric cognitive disorders

    Key finding: We identified 1 known pathogenic PSEN1 (p.His163Arg, c.488A>G) mutation and 3 novel PSEN2 mutations in 6 patients. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2014-10-15

    Complex disposition of methylthioninium redox forms determines efficacy in tau aggregation inhibitor therapy for Alzheimer's disease

    ✓ Peer-reviewed Drug development The Journal of pharmacology and experimental therapeutics

    Key finding: Although the results of a phase 2 study of MTC in 321 mild/moderate AD subjects identified a 138-mg MT/day dose as the minimum effective dose on cognitive and imaging end points, further clinical development of MT was delayed pending resolution of the unexpected lack of efficacy of the 228-mg MT/day dose.

    Full summary, score breakdown and related studies → Original source

  7. 2014-10-15

    The Mediterranean diet, its components, and cardiovascular disease

    ✓ Peer-reviewed Prevention trials The American journal of medicine

    Key finding: These enhancements easily rival those seen with more established tools used to fight cardiovascular disease such as aspirin, beta-blockers, angiotensin-converting enzyme inhibitors, and exercise. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2014-10-14

    Agitation in cognitive disorders: International Psychogeriatric Association provisional consensus clinical and research definition

    ✓ Peer-reviewed Clinical safety International Psychogeriatrics

    Key finding: Agitation was defined broadly as: (1) occurring in patients with a cognitive impairment or dementia syndrome; (2) exhibiting behavior consistent with emotional distress; (3) manifesting excessive motor activity, verbal aggression, or physical aggression; and (4) evidencing behaviors that cause excess disability and are not solely attributable to another disorder (psychiatric, medical, or substance-related). +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2014-10-14

    Maternal immune activation and abnormal brain development across CNS disorders

    ✓ Peer-reviewed Inflammation and the immune system Nature reviews. Neurology

    Key finding: Animal models have revealed maternal immune activation (mIA) to be a profound risk factor for neurochemical and behavioural abnormalities in the offspring. +2 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2014-10-14

    The Cambridge Centre for Ageing and Neuroscience (Cam-CAN) study protocol: a cross-sectional, lifespan, multidisciplinary examination of healthy cognitive ageing

    ✓ Peer-reviewed Prevention trials BMC neurology

    Key finding: Our study is a unique resource of neuroimaging and cognitive measures relevant to change across the adult lifespan. +2 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2014-10-14

    Multiple Brain Markers are Linked to Age-Related Variation in Cognition

    ✓ Peer-reviewed Hippocampus size on brain scans Cerebral cortex (New York, N.Y. : 1991)

    Key finding: We examined multiple brain markers associated with age-related variation in cognition. +2 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2014-10-14

    The phenotypic variability of amyotrophic lateral sclerosis

    ✓ Peer-reviewed Lewy body dementia Nature reviews. Neurology

    Key finding: Classic textbook neurology teaches that amyotrophic lateral sclerosis (ALS) is a degenerative disease that selectively affects upper and lower motor neurons and is fatal 3-5 years after onset--a description which suggests that the clinical presentation of ALS is very homogenous.

    Full summary, score breakdown and related studies → Original source

  13. 2014-10-12

    Machine learning framework for early MRI-based Alzheimer's conversion prediction in MCI subjects

    ✓ Peer-reviewed Digital health tools NeuroImage

    Key finding: We experimentally demonstrated the added value of these novel characteristics in predicting the MCI-to-AD conversion on data obtained from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database. +2 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2014-10-12

    A three-dimensional human neural cell culture model of Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms Nature

    Key finding: More importantly, the 3D-differentiated neuronal cells expressing FAD mutations exhibited high levels of detergent-resistant, silver-positive aggregates of phosphorylated tau in the soma and neurites, as well as filamentous tau, as detected by immunoelectron microscopy. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2014-10-08

    Physical activity attenuates age-related biomarker alterations in preclinical AD

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: In a middle-aged, at-risk cohort, a physically active lifestyle is associated with an attenuation of the deleterious influence of age on key biomarkers of AD pathophysiology. +2 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2014-10-08

    The DSM-5 criteria, level of arousal and delirium diagnosis: inclusiveness is safer

    ✓ Peer-reviewed Getting a diagnosis BMC medicine

    Key finding: Altered consciousness has been regarded as a core feature of delirium; the fact that consciousness itself should be physiologically disrupted due to acute illness attests to its clinical urgency.

    Full summary, score breakdown and related studies → Original source

  17. 2014-10-07

    Short-term trends in dementia prevalence in Germany between the years 2007 and 2009

    ✓ Peer-reviewed Digital health tools Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Data spanning more than 3 years were examined, and the examination revealed a significant yearly reduction between 1% and 2% in the prevalence of dementia among women aged 75 to 84 years. +1 more finding

    Full summary, score breakdown and related studies → Original source

  18. 2014-10-07

    Gastrostomy tube placement in patients with advanced dementia or near end of life

    ✓ Peer-reviewed End-of-life care Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition

    Key finding: This paper recommends a change in clinical practice and care strategy based on the results of a thorough literature review and provides tools for healthcare clinicians, particularly in the hospital setting, including an algorithm for decision making and a checklist to use prior to the placement of G-tubes or other long-term enteral access devices. +1 more finding

    Full summary, score breakdown and related studies → Original source

  19. 2014-10-07

    Inflammasomes in neuroinflammation and changes in brain function: a focused review

    ✓ Peer-reviewed Risk factors Frontiers in neuroscience

    Key finding: These pro-inflammatory cytokines have been shown to promote a variety of innate immune processes associated with infection, inflammation, and autoimmunity, and thereby play an instrumental role in the instigation of neuroinflammation during old age and subsequent occurrence of neurodegenerative diseases, cognitive impairment, and dementia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  20. 2014-10-07

    Hypoglycaemia in diabetes mellitus: epidemiology and clinical implications

    ✓ Peer-reviewed Risk factors Nature reviews. Endocrinology

    Key finding: Mild (self-treated) and severe (requiring help) hypoglycaemia episodes are more common in type 1 diabetes mellitus but people with insulin-treated type 2 diabetes mellitus are also exposed to frequent hypoglycaemic events, many of which occur during sleep. +4 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2014-10-07

    Brain connectivity in neurodegenerative diseases--from phenotype to proteinopathy

    ✓ Peer-reviewed Brain scans and imaging Nature reviews. Neurology

    Key finding: This Review aims to summarize current evidence that connectivity biomarkers are associated with upstream and downstream disease processes (molecular pathology and clinical symptoms, respectively) in the major neurodegenerative diseases. +1 more finding

    Full summary, score breakdown and related studies → Original source

  22. 2014-10-07

    The effects of intracranial volume adjustment approaches on multiple regional MRI volumes in healthy aging and Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging Frontiers in aging neuroscience

    Key finding: Comparing prediction of diagnostic status using the different approaches, small but significant differences were found.

    Full summary, score breakdown and related studies → Original source

  23. 2014-10-05

    Safety and efficacy of idalopirdine, a 5-HT6 receptor antagonist, in patients with moderate Alzheimer's disease (LADDER): a randomised, double-blind, placebo-controlled phase 2 trial

    ✓ Peer-reviewed Clinical trials The Lancet. Neurology

    Key finding: Between Dec 8, 2009, and Dec 23, 2011, we randomly allocated 278 patients to treatment: 133 to placebo and 145 to idalopirdine. 132 patients in the placebo group and 140 in the experimental group were included in the final analysis. +4 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2014-10-05

    Neuroinflammation in Alzheimer's disease; A source of heterogeneity and target for personalized therapy

    ✓ Peer-reviewed Inflammation and the immune system Neuroscience

    Key finding: Neuroinflammation has long been known as an accompanying pathology of Alzheimer's disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2014-10-05

    Studying ventricular abnormalities in mild cognitive impairment with hyperbolic Ricci flow and tensor-based morphometry

    ✓ Peer-reviewed Long-term cohort studies NeuroImage

    Key finding: MCI is attracting increasing attention, as it offers an opportunity to target the disease process during an early symptomatic stage. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →