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What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 19,426–19,450 of 27,380 studies, newest first · page 778 of 1096.

June 2012 17

  1. 2012-06-01

    Validity of a brief computerized cognitive screening test in dementia

    ✓ Peer-reviewed Cognitive tests and assessment Journal of geriatric psychiatry and neurology

    Key finding: CogState and standard neuropsychological task scores were significantly lower for dementia participants than that of the nondementia groups (P < .05), with a single CogState test distinguishing control from MCI participants, but minimal differentiation existing between dementias using the CogState. +1 more finding

  2. 2012-06-01

    An unconventional role for miRNA: let-7 activates Toll-like receptor 7 and causes neurodegeneration

    ✓ Peer-reviewed Tau biomarkers Nature neuroscience

    Key finding: Our results suggest that microRNAs can function as signaling molecules and identify TLR7 as an essential element in a pathway that contributes to the spread of CNS damage.

  3. 2012-06-01

    Contribution of genetic and dietary insulin resistance to Alzheimer phenotype in APP/PS1 transgenic mice

    ✓ Peer-reviewed Biomarkers Journal of cellular and molecular medicine

    Key finding: Glucose and insulin tolerance tests revealed significant hyperglycaemia in mice overexpressing IGF-2, which was exacerbated by high-fat diet. +2 more findings

  4. 2012-06-01

    Predictive neural biomarkers of clinical response in depression: a meta-analysis of functional and structural neuroimaging studies of pharmacological and psychological therapies

    ✓ Peer-reviewed Hippocampus size on brain scans Neurobiology of disease

    Key finding: We performed a systematic review and meta-analysis of neural predictors of response to the most commonly used, evidence based treatments in clinical practice, namely pharmacological and psychological therapies. +4 more findings

  5. 2012-06-01

    Neurocognitive impairment in obstructive sleep apnea

    ✓ Peer-reviewed Hippocampus size on brain scans Chest

    Key finding: Several studies have shown that OSAS has an adverse effect on inductive and deductive reasoning, attention, vigilance, learning, and memory. +1 more finding

  6. 2012-06-01

    Drug therapy optimization at the end of life

    ✓ Peer-reviewed End-of-life care Drugs & aging

    Key finding: However, discontinuation of drugs is not standard practice, and prescriptions are usually not adapted to changes in the course of advanced diseases. +4 more findings

  7. 2012-06-01

    Mediterranean diet and cognitive decline in women with cardiovascular disease or risk factors

    ✓ Peer-reviewed Prevention trials Journal of the Academy of Nutrition and Dietetics

    Key finding: In women at higher risk of cognitive decline due to vascular disease or risk factors, adherence to a Mediterranean-style diet was not associated with subsequent 5-year cognitive change. +1 more finding

  8. 2012-06-01

    Overview and Findings from the Rush Memory and Aging Project

    ✓ Peer-reviewed Long-term cohort studies Current Alzheimer Research

    The Memory and Aging Project is a longitudinal, epidemiologic clinical-pathologic cohort study of common chronic conditions of aging with an emphasis on decline in cognitive and motor function and risk of Alzheimer’s disease (AD).

  9. 2012-06-01

    ENRICH: a new innovation to facilitate dementia research in care homes

    ✓ Peer-reviewed Health systems and care delivery British Journal of Community Nursing

    Key finding: There are currently almost three times as many care home beds as NHS hospital beds in England, and the number is projected to rise significantly by 2019 (Laing and Buisson, 2009).

  10. 2012-06-01

    Large femoral heads decrease the incidence of dislocation after total hip arthroplasty: a randomized controlled trial

    ✓ Peer-reviewed Brain tissue and pathology The Journal of bone and joint surgery. American volume

    Key finding: The aim of this multicenter randomized controlled trial was to determine whether the incidence of dislocation one year after total hip arthroplasty is significantly lower in association with the use of a 36-mm femoral head articulation as compared with a 28-mm articulation. +3 more findings

  11. 2012-06-01

    Chronic traumatic encephalopathy: neurodegeneration following repetitive concussive and subconcussive brain trauma

    ✓ Peer-reviewed Brain tissue and pathology Brain imaging and behavior

    Key finding: It is thought to result in executive dysfunction, memory impairment, depression and suicidality, apathy, poor impulse control, and eventually dementia. +3 more findings

  12. 2012-06-01

    Rationale for use of the Clinical Dementia Rating Sum of Boxes as a primary outcome measure for Alzheimer's disease clinical trials

    ✓ Peer-reviewed Cognitive tests and assessment Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: The CDR-SB assesses both cognitive and functional domains of AD disability. +3 more findings

  13. 2012-06-01

    Loss of intranetwork and internetwork resting state functional connections with Alzheimer's disease progression

    ✓ Peer-reviewed How common it is The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: We observed loss of correlations within not only the DMN but other networks at CDR 0.5. +2 more findings

  14. 2012-06-01

    Multicentre population-based dementia prevalence survey in Japan: a preliminary report

    ✓ Peer-reviewed Disparities Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society

    Key finding: In total, 3394 participants were examined (participation rate: 62.5%), and 768 dementia cases and 529 mild cognitive impairment cases were identified. +4 more findings

  15. 2012-06-01

    Targeted delivery of nerve growth factor via encapsulated cell biodelivery in Alzheimer disease: a technology platform for restorative neurosurgery

    ✓ Peer-reviewed Brain scans and imaging Journal of neurosurgery

    Key finding: Object The authors describe the first clinical trial with encapsulated cell biodelivery (ECB) implants that deliver nerve growth factor (NGF) to the cholinergic basal forebrain with the intention of halting the degeneration of cholinergic neurons and the associated cognitive decline in patients with Alzheimer disease (AD).

  16. 2012-06-01

    Systematic review of atorvastatin for the treatment of Alzheimer's disease

    ✓ Peer-reviewed Treatments Neural regeneration research

    Key finding: Two randomized controlled trials were included, one was scale A, and the other was scale B. The rates of abnormal liver function, withdrawal from treatment, and withdrawal due to adverse effects were higher in the treatment group (OR = 7.86, 95%CI: 2.50-24.69; OR = 4.70, 95%CI: 2.61-8.44; and OR = 5.47, 95%CI: 3.01-9.94; respectively) compared with the placebo group. +2 more findings

  17. 2012-06-01

    Celecoxib or naproxen treatment does not benefit depressive symptoms in persons age 70 and older: findings from a randomized controlled trial

    ✓ Peer-reviewed Treatments The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    Key finding: Treatment with celecoxib or naproxen did not improve depressive symptoms over time compared with placebo. +4 more findings

May 2012 8

  1. 2012-05-31

    Nuclear factor-κB regulates βAPP and β- and γ-secretases differently at physiological and supraphysiological Aβ concentrations

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: The nuclear factor-κB (NF-κB) is a stress-activated transcription factor that is activated around senile plaques. +3 more findings

  2. 2012-05-30

    Older people dying with dementia: a nationwide study

    ✓ Peer-reviewed End-of-life care International psychogeriatrics

    Key finding: Several areas of end-of-life care provision could be improved. +2 more findings

  3. 2012-05-30

    Screening for cognitive impairment: comparing the performance of four instruments in primary care

    ✓ Peer-reviewed Disparities Journal of the American Geriatrics Society

    Key finding: In individuals without a prior diagnosis of cognitive impairment, the prevalence of dementia was low, but the prevalence of CIND was high.

  4. 2012-05-30

    A single-question screen for rapid eye movement sleep behavior disorder: a multicenter validation study

    ✓ Peer-reviewed Getting a diagnosis Movement disorders : official journal of the Movement Disorder Society

    Key finding: A single-question screen for RBD may reliably detect disease, with psychometric properties favorably comparable to those reported for longer questionnaires. +1 more finding

  5. 2012-05-29

    Structure and pathology of tau protein in Alzheimer disease

    ✓ Peer-reviewed Disparities International journal of Alzheimer's disease

    Key finding: Alterations in the amount or the structure of tau protein can affect its role as a stabilizer of microtubules as well as some of the processes in which it is implicated. +4 more findings

  6. 2012-05-29
  7. 2012-05-28

    Time to diagnosis in young-onset dementia as compared with late-onset dementia

    ✓ Peer-reviewed Brain tissue and pathology Psychological medicine

    Key finding: The extent to which specific factors influence diagnostic delays in dementia is unclear. +3 more findings

  8. 2012-05-24

    The Lewy body in Parkinson's disease and related neurodegenerative disorders

    ✓ Peer-reviewed Lewy body dementia Molecular neurobiology

    Key finding: However, recent studies have indicated that nonfibrillar α-synuclein is cytotoxic and that fibrillar aggregates of α-synuclein (LBs and pale bodies) may represent a cytoprotective mechanism in PD.

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