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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 18,151–18,175 of 27,380 studies, newest first · page 727 of 1096.

January 2014 25

  1. 2014-01-01

    Increased brain penetration and potency of a therapeutic antibody using a monovalent molecular shuttle

    ✓ Peer-reviewed Vascular contributions Neuron

    Key finding: Brain Shuttle version of an anti-Aβ antibody, which uses a monovalent binding mode to the TfR, increases β-Amyloid target engagement in a mouse model of Alzheimer's disease by 55-fold compared to the parent antibody. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2014-01-01

    BDNF and synaptic plasticity, cognitive function, and dysfunction

    ✓ Peer-reviewed Risk factors Handbook of experimental pharmacology

    Key finding: Converging evidence now strongly suggest that deficits in BDNF signaling contribute to the pathogenesis of several major diseases and disorders such as Huntington's disease, Alzheimer's disease, and depression.

    Full summary, score breakdown and related studies → Original source

  3. 2014-01-01

    The prevalence of peripheral and central hearing impairment and its relation to cognition in older adults

    ✓ Peer-reviewed Risk factors Audiology & neuro-otology

    Key finding: Recent studies have suggested that hearing loss is independently associated with poorer cognitive functioning. +1 more finding

    Full summary, score breakdown and related studies → Original source

  4. 2014-01-01

    Mitochondrial biogenesis: pharmacological approaches

    ✓ Peer-reviewed Drug development Current pharmaceutical design

    Key finding: Whereas a modest expression of this transcriptional co-activator results in positive effects, a moderate to substantial overexpession may have deleterious consequences.

    Full summary, score breakdown and related studies → Original source

  5. 2014-01-01

    Efficacy and safety of donepezil, galantamine, rivastigmine, and memantine for the treatment of Alzheimer's disease: a systematic review and meta-analysis

    ✓ Peer-reviewed Treatments Journal of Alzheimer's disease : JAD

    Key finding: Cholinesterase inhibitors and memantine are able to stabilize or slow decline in cognition, function, behavior, and global change. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2014-01-01

    Motor and cognitive advantages persist 12 months after exenatide exposure in Parkinson's disease

    ✓ Peer-reviewed Drug development Journal of Parkinson's disease

    Key finding: Compared to the control group of patients, patients previously exposed to exenatide had an advantage of 5.6 points (95% CI, 2.2-9.0; p = 0.002) using blinded video rating of the MDS-UPDRS part 3 motor subscale.

    Full summary, score breakdown and related studies → Original source

  7. 2014-01-01

    Specific targeting of tau oligomers in Htau mice prevents cognitive impairment and tau toxicity following injection with brain-derived tau oligomeric seeds

    ✓ Peer-reviewed Drug development Journal of Alzheimer's disease : JAD

    Key finding: Historically, neurofibrillary tangles have been considered the main tau species of interest in Alzheimer's disease; however, we and others have shown that tau oligomers may be the most toxic form and the species responsible for the spread of pathology. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2014-01-01

    Novel plasma biomarker surrogating cerebral amyloid deposition

    ✓ Peer-reviewed Biomarkers Proceedings of the Japan Academy. Series B, Physical and biological sciences

    Key finding: APP669-711/Aβ1-42 significantly increased in the PiB+ groups.

    Full summary, score breakdown and related studies → Original source

  9. 2014-01-01

    Developing novel blood-based biomarkers for Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Alzheimer's disease is the public health crisis of the 21st century. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2014-01-01

    Familial Alzheimer's mutations within APPTM increase Aβ42 production by enhancing accessibility of ε-cleavage site

    ✓ Peer-reviewed Biomarkers Nature communications

    Key finding: The C-terminus of Aβ is generated by γ-secretase cleavage within the transmembrane domain of APP (APPTM), a process that is primed by an initial ε-cleavage at either T48 or L49, resulting in subsequent production of Aβ42 or Aβ40, respectively. +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2014-01-01

    Abnormal amplitude of low-frequency fluctuations of intrinsic brain activity in Alzheimer's disease

    ✓ Peer-reviewed Hippocampus size on brain scans Journal of Alzheimer's disease : JAD

    Key finding: Compared to controls, AD patients showed decreased ALFF values in the bilateral PCC/PCu, inferior parietal lobe, and several temporal regions, and increased ALFF values mainly in the bilateral Hip/PHG, and middle and inferior temporal gyri. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2014-01-01

    Eating patterns are associated with cognitive function in the elderly at risk of metabolic syndrome from rural areas

    ✓ Peer-reviewed Prevention trials European review for medical and pharmacological sciences

    Key finding: Greater adherence to MedDiet and frequency of consumption of some foods were associated with better scores in several CF tests in elderly individuals with high risk of MS living in a rural community. +2 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2014-01-01

    Cognition and nutrition

    ✓ Peer-reviewed Prevention trials Current opinion in clinical nutrition and metabolic care

    Key finding: Undernutrition is associated with cognitive decline. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2014-01-01

    Mediterranean diet and cognitive decline. A lesson from the whole-diet approach: what challenges lie ahead?

    ✓ Peer-reviewed Prevention trials Journal of Alzheimer's disease : JAD

    Key finding: Higher adherence to a Mediterranean-type diet was associated with decreased cognitive decline, although the Mediterranean diet (MeDi) combines several foods, micronutrients, and macronutrients already separately proposed as potential protective factors against dementia and predementia syndromes. +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2014-01-01

    Giving words new life: generalization of word retraining outcomes in semantic dementia

    ✓ Peer-reviewed Prevention trials Journal of Alzheimer's disease : JAD

    Key finding: There was clear evidence of generalization especially in patients with milder semantic impairments. +2 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2014-01-01

    The Timecourse of Global Cognitive Gains from Supervised Computer-Assisted Cognitive Training: A Randomised, Active-Controlled Trial in Elderly with Multiple Dementia Risk Factors

    ✓ Peer-reviewed Prevention trials The journal of prevention of Alzheimer's disease

    Key finding: In older adults with multiple dementia risk factors, group-based CCT is a safe and effective intervention for enhancing overall cognition, memory and processing speed. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2014-01-01

    Is cognitive training an effective treatment for preclinical and early Alzheimer's disease?

    ✓ Peer-reviewed Prevention trials Journal of Alzheimer's disease : JAD

    Key finding: The results of drug trials in this regard have thus far been disappointing, and non-pharmacological interventions are receiving increased attention. +2 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2014-01-01

    Brain insulin resistance in Alzheimer's disease and its potential treatment with GLP-1 analogs

    ✓ Peer-reviewed Prevention trials Neurodegenerative disease management

    Key finding: A promising strategy for developing such therapies is the treatment of brain insulin resistance, a common and early feature of Alzheimer's disease, closely tied to cognitive decline and capable of promoting many biological abnormalities in the disorder. +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2014-01-01

    The potential effects of meditation on age-related cognitive decline: a systematic review

    ✓ Peer-reviewed Prevention trials Annals of the New York Academy of Sciences

    Key finding: Growing evidence suggests that cognitive training programs may have the potential to counteract this decline. +1 more finding

    Full summary, score breakdown and related studies → Original source

  20. 2014-01-01

    Metabolic correlates of Rey auditory verbal learning test in elderly subjects with memory complaints

    ✓ Peer-reviewed Disease mechanisms Journal of Alzheimer's disease : JAD

    Key finding: Patients with aMCI but not those with SMC showed the expected posterior cingulate-precuneus and parietal hypometabolism as compared to controls. +1 more finding

    Full summary, score breakdown and related studies → Original source

  21. 2014-01-01

    Health Motivation for Purchasing Local Foods in the Southeastern United States

    ✓ Peer-reviewed Risk factors 2015 Annual Meeting, January 31-February 3, 2015, Atlanta, Georgia

    Key finding: (2013), Onozaka, Nurse, and Thilmany McFadden (2010), and Wolf, Apitler, and Ahern (2005) found that health motivation can be a significant driver of local foods purchase, yet it remains unclear what specific health aspects determine consumer purchase decisions. +1 more finding

    Full summary, score breakdown and related studies → Original source

  22. 2014-01-01

    Midlife and late-life body mass index and late-life dementia: results from a prospective population-based cohort

    ✓ Peer-reviewed Brain tissue and pathology Journal of Alzheimer's disease : JAD

    Key finding: Obesity has been consistently associated with dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2014-01-01

    Determinants, MRI correlates, and prognosis of mild cognitive impairment: the Rotterdam Study

    ✓ Peer-reviewed Long-term cohort studies Journal of Alzheimer's disease : JAD

    Key finding: We investigated determinants, MRI-correlates, and prognosis of MCI within the population-based Rotterdam Study. +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2014-01-01

    Nonsteroidal anti-inflammatory drugs exposure and the central nervous system

    ✓ Peer-reviewed Long-term cohort studies Handbook of clinical neurology

    Key finding: They are employed as anti-inflammatory, analgesic, and antipyretic agents for a wide spectrum of clinical conditions. +3 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2014-01-01

    Hippocampal sclerosis of aging is a key Alzheimer's disease mimic: clinical-pathologic correlations and comparisons with both alzheimer's disease and non-tauopathic frontotemporal lobar degeneration

    ✓ Peer-reviewed Long-term cohort studies Journal of Alzheimer's disease : JAD

    Key finding: However, much remains unknown about the clinical correlates of HS-Aging pathology or the association(s) between HS-Aging, Alzheimer's disease (AD), and frontotemporal lobar degeneration (FTLD) pathology. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →