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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 17,326–17,350 of 27,380 studies, newest first · page 694 of 1096.

January 2015 25

  1. 2015-01-03

    Pseudophosphorylation of Tau at distinct epitopes or the presence of the P301L mutation targets the microtubule-associated protein Tau to dendritic spines

    ✓ Peer-reviewed Drug development Biochimica et biophysica acta

    Key finding: In determining the role physiological Fyn has in the spine localization of Tau, we found that neither were endogenous Tau levels reduced in Fyn knockout compared with wild-type synaptosomal brain fractions nor was the spine localization of over-expressed pseudophosphorylated or P301L Tau.

    Full summary, score breakdown and related studies → Original source

  2. 2015-01-03

    Relying on procedural memory to enhance independence in daily living activities: Smartphone use in a case of semantic dementia

    ✓ Peer-reviewed Cognitive tests and assessment Neuropsychological rehabilitation

    Key finding: The impact of learning to use specific smartphone applications, which display concepts and their semantic characteristics, on relearning useful significant concepts, was also explored in MH.

    Full summary, score breakdown and related studies → Original source

  3. 2015-01-03

    Early etiology of Alzheimer's disease: tipping the balance toward autophagy or endosomal dysfunction?

    ✓ Peer-reviewed Disease mechanisms Acta neuropathologica

    Key finding: While the exact pathogenic contribution of these two AD hallmarks and their abundant constituents [aggregation-prone amyloid β (Aβ) peptide species and hyperphosphorylated tau protein, respectively] remain debated, a growing body of evidence suggests that their development may be paralleled or even preceded by the alterations/dysfunctions in the endolysosomal and the autophagic system.

    Full summary, score breakdown and related studies → Original source

  4. 2015-01-02

    Improved serum leptin and ghrelin following bariatric surgery predict better postoperative cognitive function

    ✓ Peer-reviewed Cognitive tests and assessment Journal of clinical neurology (Seoul, Korea)

    Key finding: Improvements in leptin and ghrelin levels following bariatric surgery appear to contribute to postoperative cognitive benefits. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2015-01-02

    Disrupted hippocampal sharp-wave ripple-associated spike dynamics in a transgenic mouse model of dementia

    ✓ Peer-reviewed Disease mechanisms The Journal of physiology

    Key finding: These findings indicate there is reduced inhibitory control of hippocampal network events and point to a novel mechanism which may underlie the cognitive impairments in this model of dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2015-01 month only

    White Matter Microstructural Damage in Small Vessel Disease Is Associated With Montreal Cognitive Assessment But Not With Mini Mental State Examination Performances

    ✓ Peer-reviewed Cognitive tests and assessment Stroke

    Key finding: MoCA is suited for the cognitive screening of patients with small vessel disease. +2 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2015-01-01

    PON-1 and ferroxidase activities in older patients with mild cognitive impairment, late onset Alzheimer’s disease or vascular dementia

    ✓ Peer-reviewed Mild cognitive impairment Clinical Chemistry and Laboratory Medicine (CCLM)

    Key finding: A large body of evidence suggests that not only cerebral but also systemic oxidative stress (OxS) might be involved in the pathogenesis of late onset Alzheimer’s disease (LOAD) and vascular dementia (VAD), as well as of the prodromal phase of dementia, the so-called mild cognitive impairment (MCI). +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2015-01 month only

    Behavioral and Psychological Symptoms of Dementia: How Long Does Every Behavior Last, and Are Particular Behaviors Associated With PRN Antipsychotic Agent Use?

    ✓ Peer-reviewed Clinical safety Journal of Gerontological Nursing

    Key finding: Read the article, “Behavioral and Psychological Symptoms of Dementia: How Long Does Every Behavior Last, and Are Particular Behaviors Associated With PRN Antipsychotic Agent Use?” found on pages 22–37, carefully noting any tables and other illustrative materials that are included to enhance your knowledge and understanding of the content. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2015 year only

    Electroencephalographic Finding in Idiopathic REM Sleep Behavior Disorder

    ✓ Peer-reviewed Risk factors Neuropsychobiology

    Key finding: The REM sleep behavior disorder (RBD) is a type of parasomnia manifested by vivid, often frightening dreams associated with motor behaviors during REM sleep, sometimes causing injuries to patients themselves or to their bed partners. +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2015 year only

    Effects of Chronic REM Sleep Restriction on D 1 Receptor and Related Signal Pathways in Rat Prefrontal Cortex

    ✓ Peer-reviewed Risk factors BioMed Research International

    Key finding: The general state and morphology of PFC in rats were changed by CSR, and DA level and the expression of D 1 R in PFC were markedly decreased ( P < 0.01 , P < 0.05 ); the expression of phosphor-PKAc α was significantly lowered in CSR rats ( P < 0.05 ). +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2015-01 month only

    Sleep, Cognition, and Normal Aging

    ✓ Peer-reviewed Risk factors Perspectives on Psychological Science

    Key finding: Broadly speaking, sleep and cognitive functions are often related in advancing age, though the prevalence of null effects in healthy older adults (including correlations in the unexpected, negative direction) indicates that age may be an effect modifier of these associations. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2015-01-01

    Sleep-related behaviors in Alzheimer’s disease and dementia with Lewy bodies

    ✓ Peer-reviewed Risk factors Reviews in the Neurosciences

    Key finding: Prevalence studies suggest that Alzheimer’s disease (AD) and dementia with Lewy bodies (DLB) are the most common dementing illnesses in the elderly.

    Full summary, score breakdown and related studies → Original source

  13. 2015 year only

    The Relationship between Obstructive Sleep Apnea Syndrome and Apolipoprotein E Genetic Variants

    ✓ Peer-reviewed Genetics Respiration

    Key finding: The APOE3 allele was found in 97.3% (71/73) of the study population. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2015-01 month only

    Activation of an Innate Immune Receptor, Nod1, Accelerates Atherogenesis in Apoe −/− Mice

    ✓ Peer-reviewed Genetics The Journal of Immunology

    Key finding: Immunohistochemical studies revealed the increases in the accumulation of macrophages and CD3 T cells within the plaques in aortic roots. +2 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2015-01-01

    Disturbed flow induces systemic changes in metabolites in mouse plasma: a metabolomics study using ApoE −/− mice with partial carotid ligation

    ✓ Peer-reviewed Genetics American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

    Key finding: A metabolome-wide association study showed that 128 metabolites were significantly altered in the ligated mice compared with the sham group. +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2015-01 month only

    Increased Plasma S-Adenosylhomocysteine–Accelerated Atherosclerosis Is Associated With Epigenetic Regulation of Endoplasmic Reticulum Stress in apoE −/− Mice

    ✓ Peer-reviewed Genetics Arteriosclerosis, Thrombosis, and Vascular Biology

    Key finding: Plasma SAH levels and atherosclerotic lesion size were significantly increased in adenosine dialdehyde and SAH hydrolase short hairpin RNA groups when compared with control group. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2015 year only

    Regulating extracellular proteostasis capacity through the unfolded protein response

    ✓ Peer-reviewed Disease mechanisms Prion

    Key finding: Disruptions in ER protein homeostasis or proteostasis (i.e., ER stress) can facilitate the aberrant secretion of misfolded protein conformations to the extracellular space and exacerbate pathologic protein aggregation into proteotoxic species. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2015 year only

    Patterns of Tau and α-Synuclein Pathology in the Visual System

    ✓ Peer-reviewed Brain tissue and pathology Journal of Parkinson's disease

    Key finding: We detected immunoreactivity for all proteins along the optic pathway. +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2015-01 month only

    Mediterranean diet and cognitive health: an update of available knowledge

    ✓ Peer-reviewed Prevention and risk Current opinion in clinical nutrition and metabolic care

    Key finding: RECENT FINDINGS: Based on available epidemiological studies, two meta-analyses published in 2013 have underlined a protective effect of a greater MeDi adherence on cognitive health, including a reduced risk of Alzheimer's disease and cognitive impairment. +1 more finding

    Full summary, score breakdown and related studies → Original source

  20. 2015 year only

    Recent data on Mediterranean diet, cardiovascular disease, cancer, diabetes and life expectancy

    ✓ Peer-reviewed Prevention and risk Bratislavske lekarske listy

    Key finding: Benefits of dietary moderation when on a Mediterranean diet type (MD) have been known for well over half a century. +4 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2015 year only

    Traumatic brain injury and reserve

    ✓ Peer-reviewed Risk factors Handbook of clinical neurology

    Key finding: The CR model suggests the brain actively attempts to cope with brain damage by using pre-existing cognitive processing approaches or by enlisting compensatory approaches. +4 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2015 year only

    Combination Therapy of Cholinesterase Inhibitor (Donepezil or Galantamine) plus Memantine in the Okayama Memantine Study

    ✓ Peer-reviewed Treatments Journal of Alzheimer's disease : JAD

    Key finding: The addition of memantine resulted in stabilization of the Mini-Mental State Examination scores and Hasegawa dementia rating for 6 months, and then significantly declined at 12 months in both subgroups. +4 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2015 year only

    [Not Available]

    ✓ Peer-reviewed Treatments Therapie

    Key finding: Thirty-three patients were included: the revaluation of anti-dementia treatment led to 22 discontinuations and 11 continuations. +4 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2015 year only

    Ocular biomarkers of Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging Central nervous system agents in medicinal chemistry

    Key finding: Whilst these methods have reported a high degree of diagnostic specificity and accuracy, they fall significantly short in terms of practicality; they are often highly invasive, expensive or unsuitable for large-scale population screening.

    Full summary, score breakdown and related studies → Original source

  25. 2015 year only

    Neuropsychiatric Symptoms and Functional Connectivity in Mild Cognitive Impairment

    ✓ Peer-reviewed Brain scans and imaging Journal of Alzheimer's disease : JAD

    Key finding: There was a significant association between greater Affective factor symptoms and reduced FPCN connectivity (p = 0.03). +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →