Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 16,076–16,100 of 27,380 studies, newest first · page 644 of 1096.

May 2016 25

  1. 2016-05-10

    A retrospective population based cohort study of access to specialist palliative care in the last year of life: who is still missing out a decade on?

    ✓ Peer-reviewed End-of-life care BMC palliative care

    Key finding: There is small but significant increase in access to specialist palliative care services in Western Australia, specifically in patients dying with non-cancer conditions. +4 more findings

  2. 2016-05-10

    Cognition and gait in older people

    ✓ Peer-reviewed Prevention trials Maturitas

    Key finding: Structural and functional assays highlight the shared anatomic control of cognitive and gait function, mostly in the prefrontal cortices. +4 more findings

  3. 2016-05-10

    Prevalence of dementia subtypes in United States Medicare fee-for-service beneficiaries, 2011-2013

    ✓ Peer-reviewed Getting a diagnosis Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: This study is the first to document concurrent prevalence of primary dementia subtypes among this US population.

  4. 2016-05-09

    Optical coherence tomography and neurodegeneration: are eyes the windows to the brain?

    ✓ Peer-reviewed Brain scans and imaging Expert review of neurotherapeutics

    Key finding: Central nervous system (CNS) pathologies have ocular manifestations due to direct and/or retrograde degeneration of the visual pathways, most often related to a direct injury to the optic nerve, retinal ganglion cells and/or its surrounding cells.

  5. 2016-05-09

    Triggering Receptor Expressed on Myeloid Cells 2 Deficiency Alters Acute Macrophage Distribution and Improves Recovery after Traumatic Brain Injury

    ✓ Peer-reviewed TREM2 and immune genetics Journal of neurotrauma

    Key finding: There is increasing evidence that persons exposed to TBI have increased risk of the development of multiple neurodegenerative conditions, including Alzheimer disease (AD). +3 more findings

  6. 2016-05-07

    Impaired protein degradation in FTLD and related disorders

    ✓ Peer-reviewed Disease mechanisms Ageing research reviews

    Key finding: FTD-linked mutations in genes encoding three autophagy adaptor proteins, p62/SQSTM1, ubiquilin 2 and optineurin, indicate that impaired autophagy might cause FTD.

  7. 2016-05-07

    Impaired fasting glucose is associated with increased regional cerebral amyloid

    ✓ Peer-reviewed Genetics Neurobiology of aging

    Key finding: The Alzheimer's disease risk gene apolipoprotein E epsilon 4 (APOE ε4) is associated with increased cerebral amyloid. +3 more findings

  8. 2016-05-06

    Default mode network differences between rigidity- and tremor-predominant Parkinson's disease

    ✓ Peer-reviewed Brain scans and imaging Cortex; a journal devoted to the study of the nervous system and behavior

    Key finding: There was decreased activity in the left inferior parietal cortex (IPC) and the left posterior cingulate cortex (PCC) within the DMN between PDAR and both HC and PDT subjects, even after controlling for multiple comparisons, but not between PDT and HC. +4 more findings

  9. 2016-05-06

    New relationships and intimacy in long-term care: The views of relatives of residents with dementia and care home staff

    ✓ Peer-reviewed Health systems and care delivery Dementia

    Key finding: The views of care home staff and relatives had similarities in general terms regarding the problems arising around expressions of sexuality in care homes: indicting that a light-hearted or non-physical connection between residents is deemed acceptable, but the moment it becomes a sexual relationship then decision making becomes more complicated. +4 more findings

  10. 2016-05-06

    Common neurodegenerative pathways in obesity, diabetes, and Alzheimer's disease

    ✓ Peer-reviewed Risk factors Biochimica et biophysica acta. Molecular basis of disease

    Key finding: Damage to the blood brain barrier (BBB) as seen with aging can lead to infiltration of immune cells into the brain, leading to the exacerbation of central inflammation. +4 more findings

  11. 2016-05-06

    What is the association between sedentary behaviour and cognitive function? A systematic review

    ✓ Peer-reviewed Prevention and risk British journal of sports medicine

    Key finding: 8 studies examined the association of sedentary behaviour with cognitive function. 6 studies reported significant negative associations between sedentary behaviour and cognitive function. 8 different measures of sedentary behaviour and 13 different measures of cognitive function were used across all eight studies. +4 more findings

  12. 2016-05-05

    Apolipoprotein E lipoprotein particles inhibit amyloid-β uptake through cell surface heparan sulphate proteoglycan

    ✓ Peer-reviewed Genetics Molecular neurodegeneration

    Key finding: In this study, we show that apoE lipoprotein particles from conditioned media of immortalized astrocytes isolated from human APOE-targeted replacement (TR) mice significantly suppress cellular Aβ42 and Aβ40 uptake through cell surface HSPG. +4 more findings

  13. 2016-05-05

    The Health and Well-Being of Older Adults with Dual Sensory Impairment (DSI) in Four Countries

    ✓ Peer-reviewed Risk factors PloS one

    Key finding: Raising awareness of this unique disability is imperative to insure that individuals receive the necessary rehabilitation and supportive services to improve their level of independence and quality of life. +1 more finding

  14. 2016-05-05

    Discovery of 6-(Fluoro-(18)F)-3-(1H-pyrrolo[2,3-c]pyridin-1-yl)isoquinolin-5-amine ([(18)F]-MK-6240): A Positron Emission Tomography (PET) Imaging Agent for Quantification of Neurofibrillary Tangles (NFTs)

    ✓ Peer-reviewed Brain scans and imaging Journal of medicinal chemistry

    Key finding: Neurofibrillary tangles (NFTs) made up of aggregated tau protein have been identified as the pathologic hallmark of several neurodegenerative diseases including Alzheimer's disease. +2 more findings

  15. 2016-05-05

    Kinetics of the Tau PET Tracer 18F-AV-1451 (T807) in Subjects with Normal Cognitive Function, Mild Cognitive Impairment, and Alzheimer Disease

    ✓ Peer-reviewed Brain scans and imaging Journal of nuclear medicine : official publication, Society of Nuclear Medicine

    Key finding: We report kinetic modeling results of dynamic acquisition data from 0 to 100 min after injection with the tau PET tracer 18 F-AV-1451 in 19 subjects. +1 more finding

  16. 2016-05-05

    Long-Term Population-Based Cerebral Ischemic Event and Cognitive Outcomes of Direct Oral Anticoagulants Compared With Warfarin Among Long-term Anticoagulated Patients for Atrial Fibrillation

    ✓ Peer-reviewed Prevention and risk The American journal of cardiology

    Key finding: The use of DOACs compared with warfarin was associated with a reduced risk of long-term adverse outcomes: death (p = 0.09), stroke/TIA (p <0.0001), major bleed (p <0.0001), and bleed (p = 0.14). +3 more findings

  17. 2016-05-04

    Cholinesterase Inhibitor Utilization: The Impact of Provincial Drug Policy on Discontinuation

    ✓ Peer-reviewed Treatments Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

    Key finding: Patients who started ChEI therapy after the introduction of the coverage policy had a significantly longer persistence. +4 more findings

  18. 2016-05-04

    A Multimodal Structural and Functional Neuroimaging Study of Amnestic Mild Cognitive Impairment

    ✓ Peer-reviewed Brain scans and imaging The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    Key finding: Patients with aMCI showed significant gray matter volumetric reductions in bilateral parahippocampal gyri as well as multiple other brain regions including frontal, temporal, and parietal cortices. +2 more findings

  19. 2016-05-04

    Tau: From research to clinical development

    ✓ Peer-reviewed Brain scans and imaging Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Tau pathology is recognized as the key driver of disease progression in Alzheimer's and other neurodegenerative diseases. +4 more findings

  20. 2016-05-03

    Pharmacologic Treatment of Insomnia Disorder: An Evidence Report for a Clinical Practice Guideline by the American College of Physicians

    ✓ Peer-reviewed Clinical safety Annals of internal medicine

    Key finding: Data synthesis Eszopiclone, zolpidem, and suvorexant improved short-term global and sleep outcomes compared with placebo, although absolute effect sizes were small (low- to moderate-strength evidence). +3 more findings

  21. 2016-05-02
  22. 2016-05-01

    The American Psychiatric Association Practice Guideline on the Use of Antipsychotics to Treat Agitation or Psychosis in Patients With Dementia

    ✓ Peer-reviewed Clinical safety American Journal of Psychiatry

    Key finding: Author(s): Reus, Victor I; Fochtmann, Laura J; Eyler, A Evan; Hilty, Donald M; Horvitz-Lennon, Marcela; Jibson, Michael D; Lopez, Oscar L; Mahoney, Jane; Pasic, Jagoda; Tan, Zaldy S; Wills, Cheryl D; Rhoads, Richard; Yager, Joel

  23. 2016-05-01

    Pericytes of the neurovascular unit: key functions and signaling pathways

    ✓ Peer-reviewed Inflammation and the immune system Nature neuroscience

    Key finding: CNS pericytes are uniquely positioned in the neurovascular unit between endothelial cells, astrocytes and neurons. +4 more findings

  24. 2016-05-01

    Association of Antipsychotic Use With Mortality Risk in Patients With Parkinson Disease

    ✓ Peer-reviewed Clinical safety JAMA neurology

    Key finding: The use of APs by patients with dementia in the general population is associated with increased mortality, but whether this risk extends to patients with PD remains unknown. +4 more findings

  25. 2016-05-01

    Healthy cognitive aging and dementia prevention

    ✓ Peer-reviewed Prevention trials The American psychologist

    Key finding: Behavioral prevention strategies can help maintain high levels of cognition and functional integrity, and can reduce the social, medical, and economic burden associated with cognitive aging and age-associated neurodegenerative diseases.

Browse the library by subject, with the full score breakdown →