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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 11,076–11,100 of 27,380 studies, newest first · page 444 of 1096.

October 2020 25

  1. 2020-10-15

    Causal Associations Between Modifiable Risk Factors and the Alzheimer's Phenome

    ✓ Peer-reviewed Hippocampus size on brain scans Annals of neurology

    Key finding: Our comprehensive examination of the genetic evidence for the causal relationships between previously reported risk factors in AD using PRS and MR supports a causal role for education, blood pressure, cholesterol levels, smoking, and diabetes with the AD phenome. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2020-10-15

    Small molecule therapeutics for tauopathy in Alzheimer's disease: Walking on the path of most resistance

    ✓ Peer-reviewed Disease mechanisms European journal of medicinal chemistry

    Key finding: Overall, this work aims to provide a comprehensive and critical overview of small molecules which are being explored as a lead candidate for discovering drugs against tauopathy in AD.

    Full summary, score breakdown and related studies → Original source

  3. 2020-10-14

    Semaglutide-mediated protection against Aβ correlated with enhancement of autophagy and inhibition of apotosis

    ✓ Peer-reviewed Drug development Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia

    Key finding: Our results provide a clue for the hypothesis that autophagy enhancement and apoptosis inhibition may be involved in the effect of semaglutide to protect against Aβ 25-35 . +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2020-10-14

    Advance care planning information intervention for persons with mild dementia and their family caregivers: Impact on end-of-life care decision conflicts

    ✓ Peer-reviewed End-of-life care PloS one

    Key finding: The intervention resulted in significant improvements among persons with dementia and FCGs for knowledge of end-stage dementia treatment (p = .008 and p < .001, respectively), knowledge of ACP (both p < .001), and significant reductions in decisional conflicts (both p < .001).

    Full summary, score breakdown and related studies → Original source

  5. 2020-10-14

    Cognitive Training Using Fully Immersive, Enriched Environment Virtual Reality for Patients With Mild Cognitive Impairment and Mild Dementia: Feasibility and Usability Study

    ✓ Peer-reviewed Prevention trials JMIR serious games

    Key finding: Participants included 10 physiatrists, 6 OTs, and 11 patients with mild cognitive impairment and mild dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2020-10-14

    The Effects of COVID-19 and Quarantine Measures on the Lifestyles and Mental Health of People Over 60 at Increased Risk of Dementia

    ✓ Peer-reviewed Prevention trials Frontiers in psychiatry

    Key finding: The sample included 55.6% patients with MCI and 56 people with SCD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2020-10-14

    Microglia in Alzheimer's Disease in the Context of Tau Pathology

    ✓ Peer-reviewed TREM2 and immune genetics Biomolecules

    Key finding: First described more than a century ago, these cells were initially assigned a secondary role in the central nervous system (CNS) with respect to the protagonists, neurons. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2020-10-14

    Impact of dementia on informal care: a systematic review of family caregivers' perceptions

    ✓ Peer-reviewed Caregiving BMJ supportive & palliative care

    Key finding: Eighty-one studies with 3347 participants were included in this review.

    Full summary, score breakdown and related studies → Original source

  9. 2020-10-13

    Cadmium and Lead Exposure, Nephrotoxicity, and Mortality

    ✓ Peer-reviewed Risk factors Toxics

    Key finding: The present review aims to provide an update on health risks associated with the low-to-moderate levels of environmental cadmium (Cd) and lead (Pb) to which most populations are exposed. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2020-10-13

    TREM2 overexpression rescues cognitive deficits in APP/PS1 transgenic mice by reducing neuroinflammation via the JAK/STAT/SOCS signaling pathway

    ✓ Peer-reviewed TREM2 and immune genetics Experimental neurology

    Key finding: Triggering receptor expressed on myeloid cells-2 (TREM2), a type I transmembrane receptor, expressed uniquely by microglia in the brain, is involved in the neuroinflammatory responses of AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2020-10-13

    The role of TDP-43 propagation in neurodegenerative diseases: integrating insights from clinical and experimental studies

    ✓ Peer-reviewed Lewy body dementia Experimental & molecular medicine

    Key finding: Accumulating evidence suggests that prion-like spreading of aberrant protein aggregates composed of tau, amyloid-β, and α-synuclein is involved in the progression of neurodegenerative diseases such as AD and PD.

    Full summary, score breakdown and related studies → Original source

  12. 2020-10-12

    Clusterin as a Potential Biomarker of Obesity-Related Alzheimer's Disease Risk

    ✓ Peer-reviewed Risk factors Biomarker insights

    Key finding: Despite long-standing interest in elucidating clusterin's relationship with amyloid beta (Aβ) aggregation/clearance and toxicity, significant knowledge gaps still exist. +1 more finding

    Full summary, score breakdown and related studies → Original source

  13. 2020-10-12

    Association of Enlarged Perivascular Spaces and Measures of Small Vessel and Alzheimer Disease

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: EPVS are related to SVD, also in early disease stages, but the lack of correlation with cognition suggests that their importance is limited. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2020-10-11

    The SARS-CoV-2 spike protein alters barrier function in 2D static and 3D microfluidic in-vitro models of the human blood-brain barrier

    ✓ Peer-reviewed Risk factors Neurobiology of disease

    Key finding: Thus, the results presented in this report explored whether deleterious outcomes from the SARS-CoV-2 viral spike protein on primary human brain microvascular endothelial cells (hBMVECs) could be observed. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2020-10-10

    Inclusion of African American/Black adults in a pilot brain proteomics study of Alzheimer's disease

    ✓ Peer-reviewed Disparities Neurobiology of disease

    Key finding: Herein, we conducted a pilot proteomics study of postmortem brains from African American/Black and non-Hispanic White adults neuropathologically diagnosed with AD compared to closely-matched cognitively normal individuals. +2 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2020-10-10

    Autophagy and heat-shock response impair stress granule assembly during cellular senescence

    ✓ Peer-reviewed Disease mechanisms Mechanisms of ageing and development

    Key finding: Previously, we demonstrated that senescent cells, which accumulate with age, exposed to chronic oxidative stress, are unable to form SGs.

    Full summary, score breakdown and related studies → Original source

  17. 2020-10-10

    Integrative genomics approach identifies conserved transcriptomic networks in Alzheimer's disease

    ✓ Peer-reviewed Genetics Human molecular genetics

    Key finding: Additionally, we validate our results in multiple published human AD gene expression datasets, which can be easily accessed using our online resource (https://swaruplab.bio.uci.edu/consensusAD).

    Full summary, score breakdown and related studies → Original source

  18. 2020-10-09

    MRI phenotyping of underlying cerebral small vessel disease in mixed hemorrhage patients

    ✓ Peer-reviewed Vascular contributions Journal of the neurological sciences

    Key finding: We included 110 patients with CAA (strictly lobar ICHs/CMBs), 33 with HA (strictly deep ICHs/CMBs) and 97 with mixed lobar/deep ICHs/CMBs. +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2020-10-09

    Symptomatic amyloid-related imaging abnormalities in an APOE ε4/ε4 patient treated with aducanumab

    ✓ Peer-reviewed Treatments Alzheimer's & dementia (Amsterdam, Netherlands)

    Key finding: Acute symptoms included headache and encephalopathy, and magnetic resonance imaging revealed ARIA-E and ARIA-H. +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2020-10-09

    Alzheimer-Related Cerebrovascular Disease in Down Syndrome

    ✓ Peer-reviewed Brain scans and imaging Annals of neurology

    Key finding: There were detectable WMH, enlarged PVS, infarcts, and microbleeds as early as the 5th decade of life. +1 more finding

    Full summary, score breakdown and related studies → Original source

  21. 2020-10-08

    Using Medicare claims in identifying Alzheimer's disease and related dementias

    ✓ Peer-reviewed Costs and economics Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: We found that four items-a Medicare claim recording ADRD 1 year ago, 2 years ago, 3 years ago, and a total stay of 6 months in a nursing home-exhibit a pattern of association consistent with a single underlying ADRD construct, and presence of any two of these four items predict a direct measure of cognitive function and also future claims for ADRD. +2 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2020-10-08

    Retinal imaging in Alzheimer's and neurodegenerative diseases

    ✓ Peer-reviewed Brain scans and imaging Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: In the last 20 years, research focused on developing retinal imaging as a source of potential biomarkers for Alzheimer's disease and other neurodegenerative diseases, has increased significantly. +1 more finding

    Full summary, score breakdown and related studies → Original source

  23. 2020-10-08

    Depression Is Associated With Preserved Cortical Thickness Relative to Apathy in Frontotemporal Dementia

    ✓ Peer-reviewed Brain scans and imaging Journal of geriatric psychiatry and neurology

    Key finding: Apathy severity was significantly associated with cortical thinning of the lateral parts of the right sided frontal, temporal and parietal lobes. +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2020-10-08

    Detection of Mild Cognitive Impairment Through Natural Language and Touchscreen Typing Processing

    ✓ Peer-reviewed Cognitive tests and assessment Frontiers in digital health

    Key finding: The acquired results have shown: (a) keystroke features with a k-NN classifier achieved an Area Under Curve (AUC) of 0.78 [95% confidence interval (CI):0.68-0.88; specificity/sensitivity (SP/SE): 0.64/0.92], (b) NLP features with a Logistic regression classifier achieved an AUC of 0.76 (95% CI: 0.65-0.85; SP/SE: 0.80/0.71), and (c) an ensemble model with the fusion of keystroke and NLP features resulted in AUC of 0.75 (95% CI:0.63-0.86; SP/SE 0.90/0.60).

    Full summary, score breakdown and related studies → Original source

  25. 2020-10-08

    Plasma Aβ and neurofilament light chain are associated with cognitive and physical function decline in non-dementia older adults

    ✓ Peer-reviewed Prevention trials Alzheimer's research & therapy

    Key finding: Combined low plasma Aβ 42 /Aβ 40 ratio and high plasma NfL level was associated with greater declines in cognition and gait speed over time, providing further evidence of the links between cognitive and physical function. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →