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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 23,576–23,600 of 27,380 studies, newest first · page 944 of 1096.

August 2005 5

  1. 2005-08-01

    Longitudinal volumetric MRI change and rate of cognitive decline

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: Hippocampal volume was the primary determinant of memory decline, whereas executive function (EXEC) decline was related to multiple brain components. +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2005-08-01

    The AD8: a brief informant interview to detect dementia

    ✓ Peer-reviewed Getting a diagnosis Neurology

    Key finding: The AD8 is a brief, sensitive measure that reliably differentiates between nondemented and demented individuals. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2005-08-01

    The prevention of hip fracture with risedronate and ergocalciferol plus calcium supplementation in elderly women with Alzheimer disease: a randomized controlled trial

    ⚠ Retracted — do not rely on it Treatments Archives of internal medicine

    Key finding: Elderly patients with AD hypovitaminosis D are at increased risk for hip fracture. +2 more findings

    Scored 36 on our rubric, shown as 16: non-peer-reviewed sources are capped at 16. See the breakdown.

    Full summary, score breakdown and related studies → Original source

  4. 2005-08-01

    Modulation of apolipoprotein E structure by domain interaction: differences in lipid-bound and lipid-free forms

    ✓ Peer-reviewed Genetics The Journal of biological chemistry

    Key finding: Both methods demonstrated that the two domains are closer in both lipid-free and phospholipid-bound apoE4 than in apoE3 as a result of domain interaction. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2005-08-01

    Increased hippocampal activation in mild cognitive impairment compared to normal aging and AD

    ✓ Peer-reviewed Genetics Neurology

    Key finding: The authors hypothesize that there is a phase of increased medial temporal lobe activation early in the course of prodromal Alzheimer disease followed by a subsequent decrease as the disease progresses.

    Full summary, score breakdown and related studies → Original source

July 2005 20

  1. 2005-07-24

    Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia

    ✓ Peer-reviewed Lewy body dementia Nature genetics

    Key finding: Here we identify a mutation in CHMP2B, encoding a component of the endosomal ESCRTIII complex, and show that it results in aberrant mRNA splicing in tissue samples from affected members of this family. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2005-07-20

    The evolution and pathology of frontotemporal dementia

    ✓ Peer-reviewed How common it is Brain : a journal of neurology

    Key finding: Tau positive histologies of CBD, PSP and Pick bodies were most frequently associated with PPA onset or CBDS/PSP, but behavioural symptoms were also common.

    Full summary, score breakdown and related studies → Original source

  3. 2005-07-18

    The senescence-accelerated prone mouse (SAMP8): a model of age-related cognitive decline with relevance to alterations of the gene expression and protein abnormalities in Alzheimer's disease

    ✓ Peer-reviewed Genetics Experimental gerontology

    Key finding: Therefore, this mini review examines the recent findings of SAMP8 mice abnormalities at the gene and protein levels. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2005-07-18

    BRI2 interacts with amyloid precursor protein (APP) and regulates amyloid beta (Abeta) production

    ✓ Peer-reviewed Risk genes beyond APOE The Journal of biological chemistry

    Key finding: A specific interaction between BRI2 and APP was unveiled by immunoprecipitation experiments using transfected and non-transfected cells. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2005-07-17

    Regulation of NMDA receptor trafficking by amyloid-beta

    ✓ Peer-reviewed Disease mechanisms Nature neuroscience

    Key finding: We found that application of amyloid-beta promoted endocytosis of NMDA receptors in cortical neurons.

    Full summary, score breakdown and related studies → Original source

  6. 2005-07-14

    Amyloid ion channels: a common structural link for protein-misfolding disease

    ✓ Peer-reviewed Brain tissue and pathology Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Protein conformational diseases, including Alzheimer's, Huntington's, and Parkinson's diseases, result from protein misfolding, giving a distinct fibrillar feature termed amyloid.

    Full summary, score breakdown and related studies → Original source

  7. 2005-07-14

    Self-esteem, locus of control, hippocampal volume, and cortisol regulation in young and old adulthood

    ✓ Peer-reviewed Hippocampus size on brain scans NeuroImage

    Key finding: Self-esteem, the value we place on ourselves, has been associated with effects on health, life expectancy, and life satisfaction. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2005-07-14

    Tau Suppression in a Neurodegenerative Mouse Model Improves Memory Function

    ✓ Peer-reviewed Disease mechanisms Science

    Neurofibrillary tangles (NFTs) are the most common intraneuronal inclusion in the brains of patients with neurodegenerative diseases and have been implicated in mediating neuronal death and cognitive deficits.

    Full summary, score breakdown and related studies → Original source

  9. 2005-07-14

    Cognitive frailty: Predementia syndrome and vascular risk factors

    ✓ Peer-reviewed Genetics Neurobiology of aging

    Key finding: Prevalence and incidence of different predementia syndromes vary as a result of different diagnostic criteria, as well as different sampling and assessment procedures. +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2005-07-07

    White matter changes in mild cognitive impairment and AD: A diffusion tensor imaging study

    ✓ Peer-reviewed Brain scans and imaging Neurobiology of aging

    Key finding: Voxel-by-voxel comparisons showed significant regional reductions of FA in participants with MCI and AD compared to controls in multiple posterior white matter regions.

    Full summary, score breakdown and related studies → Original source

  11. 2005-07-07

    Beta-amyloid-induced dynamin 1 depletion in hippocampal neurons. A potential mechanism for early cognitive decline in Alzheimer disease

    ✓ Peer-reviewed Disease mechanisms The Journal of biological chemistry

    Key finding: We report here that beta-amyloid (Abeta), the main component of senile plaques, induced a significant decrease in dynamin 1, a protein that is essential for synaptic vesicle recycling and, hence, for memory formation and information processing. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2005-07-06

    The pathological basis of semantic dementia

    ✓ Peer-reviewed Clinical safety Brain : a journal of neurology

    Key finding: Two cases had Alzheimer's disease and significant coincidental Alzheimer-type pathology was also found in one of the ubiquitin inclusion cases.

    Full summary, score breakdown and related studies → Original source

  13. 2005-07-01

    Mild Cognitive Impairment as a Clinical Entity and Treatment Target

    ✓ Peer-reviewed Mild cognitive impairment Archives of Neurology

    Key finding: Several studies on longitudinal populations were conducted, some retrofitting criteria to longitudinal studies of aging, and several others are either underway or completed and have demonstrated a progression from MCI to AD at an elevated rate over the base rate in the population. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2005-07-01

    The non-motor symptom complex of Parkinson's disease: a comprehensive assessment is essential

    ✓ Peer-reviewed Costs and economics Current neurology and neuroscience reports

    Key finding: Parkinson's disease (PD) is a progressive disease that usually affects the motor system but is also associated with a non-motor symptom (NMS) complex that ranges from dribbling saliva, constipation, depression, sleep disorders, apathy, hallucinations, and dementia. +2 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2005-07-01

    Invited review: Bovine milk fat globule membrane as a potential nutraceutical

    ✓ Peer-reviewed Disease mechanisms Journal of dairy science

    Key finding: For the last 15 yr, a great deal of knowledge has been accumulated on health beneficial factors, protein and nonprotein, of bovine milk fat globule membrane (MFGM). +2 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2005-07-01

    Potential occupational risks for neurodegenerative diseases

    ✓ Peer-reviewed Risk factors American journal of industrial medicine

    Key finding: Support was observed for hypothesized excess neurodegenerative disease associated with a variety of occupations, 60 Hz magnetic fields and welding. +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2005-07-01

    Statin use and the risk of incident dementia: the Cardiovascular Health Study

    ✓ Peer-reviewed Drug development Archives of neurology

    Key finding: In this cohort study, statin therapy was not associated with a decreased risk of dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2005-07-01

    Enhancing central nervous system endogenous GLP-1 receptor pathways for intervention in Alzheimer's disease

    ✓ Peer-reviewed Drug development Current Alzheimer research

    Key finding: The biochemical cascades activated by neural GLP-1R stimulation are discussed in comparison to those activated by pancreatic receptors, and, additionally, are compared to signaling pathways associated with the classical neurotrophins.

    Full summary, score breakdown and related studies → Original source

  19. 2005-07-01

    Chronic traumatic encephalopathy in a National Football League player

    ✓ Peer-reviewed Genetics Neurosurgery

    Key finding: This case highlights potential long-term neurodegenerative outcomes in retired professional National Football League players subjected to repeated mild traumatic brain injury. +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2005-07-01

    Structural and functional brain development after hydrocortisone treatment for neonatal chronic lung disease

    ✓ Peer-reviewed Hippocampus size on brain scans Pediatrics

    Key finding: Prematurity is associated with mild brain structural differences that persist at 8 years of age, with associated lower scores in neurocognitive assessments. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →