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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 17,076–17,100 of 27,380 studies, newest first · page 684 of 1096.

March 2015 25

  1. 2015-03-31

    Reactive microglia drive tau pathology and contribute to the spreading of pathological tau in the brain

    ✓ Peer-reviewed Inflammation and the immune system Brain

    Key finding: We have previously shown that the deficiency of the microglial fractalkine receptor (CX3CR1) led to the acceleration of tau pathology and memory impairment in an hTau mouse model of tauopathy. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2015-03-31

    UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

    ✓ Peer-reviewed Long-term cohort studies PLoS Medicine

    Key finding: Points• UK Biobank is a very large and detailed prospective study with over 500,000 participants aged 40-69 years when recruited in 2006-2010.• The study has collected and continues to collect extensive phenotypic and genotypic detail about its participants, including data from questionnaires, physi

    Full summary, score breakdown and related studies → Original source

  3. 2015-03-31

    Would older adults with mild cognitive impairment adhere to and benefit from a structured lifestyle activity intervention to enhance cognition?: a cluster randomized controlled trial

    ✓ Peer-reviewed Cognitive tests and assessment PloS one

    Key finding: Epidemiologic evidence suggests that cognitive and physical activities are associated with better cognition in late life. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2015-03-30

    Prevalence of epilepsy among people with intellectual disabilities: A systematic review

    ✓ Peer-reviewed Down syndrome and Alzheimer's Seizure

    Key finding: Epilepsy is highly prevalent in people with intellectual disabilities.

    Full summary, score breakdown and related studies → Original source

  5. 2015-03-30

    A Prospective, Longitudinal Study of the Effect of Remission on Cortical Thickness and Hippocampal Volume in Patients with Treatment-Resistant Depression

    ✓ Peer-reviewed Hippocampus size on brain scans The international journal of neuropsychopharmacology

    Key finding: The results suggest that longitudinal structural trajectories may differ in major depressive disorder patients according to their clinical response to treatment. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2015-03-30

    Transitions between health care settings in the final three months of life in four EU countries

    ✓ Peer-reviewed End-of-life care European journal of public health

    Key finding: End-of-life transitions between health care settings are common across EU countries, in particular late hospitalizations for people residing at home.

    Full summary, score breakdown and related studies → Original source

  7. 2015-03-29

    Atrophy of presubiculum and subiculum is the earliest hippocampal anatomical marker of Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging Alzheimer's & dementia (Amsterdam, Netherlands)

    Key finding: The volumes of the presubiculum and subiculum presented the most remarkable reduction in the patient's groups. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2015-03-29

    Can agrin cerebrospinal fluid concentration be used as an early biomarker for Alzheimer's disease?

    ✓ Peer-reviewed Tau biomarkers Alzheimer's & dementia (Amsterdam, Netherlands)

    Key finding: The levels of agrin CSF were not significantly divergent among the different patient groups and did not correlate with the concentration of Aβ42, total tau, phosphorylated tau, or the Mini Mental State Examination scores. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2015-03-29

    Reduced plasma desmosterol-to-cholesterol ratio and longitudinal cognitive decline in Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Alzheimer's & dementia (Amsterdam, Netherlands)

    Key finding: Plasma DES/CHO was significantly reduced in Japanese AD patients and significantly correlated with Mini-Mental State Examination (MMSE) score. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2015-03-29

    Automatic speech analysis for the assessment of patients with predementia and Alzheimer's disease

    ✓ Peer-reviewed Digital health tools Alzheimer's & dementia (Amsterdam, Netherlands)

    Key finding: Automatic speech analyses could be an additional objective assessment tool for elderly with cognitive decline.

    Full summary, score breakdown and related studies → Original source

  11. 2015-03-28

    FIBT versus florbetaben and PiB: a preclinical comparison study with amyloid-PET in transgenic mice

    ✓ Peer-reviewed Brain scans and imaging EJNMMI research

    Key finding: We found that FIBT (2-(p-methylaminophenyl)-7-(2-[(18)F]fluoroethoxy)imidazo[2,1-b]benzothiazole) compares favorably to florbetaben as a high-contrasting PET radiopharmaceutical for imaging Aβ pathology. +4 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2015-03-28

    Different Experiences and Goals in Different Advanced Diseases: Comparing Serial Interviews With Patients With Cancer, Organ Failure, or Frailty and Their Family and Professional Carers

    ✓ Peer-reviewed End-of-life care Journal of pain and symptom management

    Key finding: These contrasting illness narratives affect and shape the experiences, thoughts, and fears of patients and their carers in the last months of life.

    Full summary, score breakdown and related studies → Original source

  13. 2015-03-28

    Traumatic brain injury in later life increases risk for Parkinson disease

    ✓ Peer-reviewed Risk factors Annals of neurology

    Key finding: Among patients aged ≥55 years presenting to inpatient/ED settings with trauma, TBI is associated with a 44% increased risk of developing PD over 5 to 7 years that is unlikely to be due to confounding or reverse causation. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2015-03-27

    Florbetaben PET imaging to detect amyloid beta plaques in Alzheimer's disease: Phase 3 study

    ✓ Peer-reviewed Brain scans and imaging Alzheimer s & Dementia

    Florbetaben PET shows high sensitivity and specificity for the detection of histopathology-confirmed neuritic β-amyloid plaques and may thus be a valuable adjunct to clinical diagnosis, particularly for the exclusion of AD.

    Full summary, score breakdown and related studies → Original source

  15. 2015-03-26

    Is the risk of Alzheimer's disease and dementia declining?

    ✓ Peer-reviewed Clinical safety Alzheimer's research & therapy

    Key finding: At least nine recent population-based studies of dementia incidence or prevalence have shown a declining age-specific risk in the US, England, The Netherlands, Sweden, and Denmark. +1 more finding

    Full summary, score breakdown and related studies → Original source

  16. 2015-03-26

    Bioenergetic mechanisms in astrocytes may contribute to amyloid plaque deposition and toxicity

    ✓ Peer-reviewed Biomarkers The Journal of biological chemistry

    Key finding: Here we show that, in cultures of human fetal astrocytes, pharmacological inhibition or molecular down-regulation of a main enzymatic regulator of glycolysis, 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase (PFKFB3), results in increased accumulation of Aβ within and around astrocytes and greater vulnerability of these cells to Aβ toxicity. +2 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2015-03-25

    From prescription drug purchases to drug use periods – a second generation method (PRE2DUP)

    ✓ Peer-reviewed Health systems and care delivery BMC medical informatics and decision making

    Key finding: PRE2DUP method gives highly accurate drug use periods for most drug classes, especially those meant for long-term use.

    Full summary, score breakdown and related studies → Original source

  18. 2015-03-24

    Anti-Inflammatory and Antiatherogenic Effects of the NLRP3 Inflammasome Inhibitor Arglabin in ApoE 2 .Ki Mice Fed a High-Fat Diet

    ✓ Peer-reviewed Genetics Circulation

    Key finding: A marked reduction in atherosclerotic lesions was observed. +1 more finding

    Full summary, score breakdown and related studies → Original source

  19. 2015-03-24

    Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia

    ✓ Peer-reviewed Genetics Nature neuroscience

    Key finding: Gene-based rare variant analysis identified an exome-wide significant enrichment of eight loss-of-function (LoF) mutations in TBK1 (encoding TANK-binding kinase 1) in 13 fALS pedigrees. +1 more finding

    Full summary, score breakdown and related studies → Original source

  20. 2015-03-24

    Co-morbidity and systemic inflammation as drivers of cognitive decline: new experimental models adopting a broader paradigm in dementia research

    ✓ Peer-reviewed Inflammation and the immune system Alzheimer's research & therapy

    Key finding: However, significant variability and overlap exists in the extent of amyloid-β and Tau pathology in AD and non-demented populations and it is clear that other factors must influence progression of cognitive decline, perhaps independent of effects on amyloid pathology. +3 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2015-03-23

    Clinicopathologic and 11C-Pittsburgh compound B implications of Thal amyloid phase across the Alzheimer's disease spectrum

    ✓ Peer-reviewed Getting a diagnosis Brain : a journal of neurology

    Key finding: Second, we examined the relevance of Thal amyloid phase in a prospectively-followed autopsied cohort who underwent ante-mortem (11)C-Pittsburgh compound B imaging; using the large autopsy cohort to broaden our perspective of (11)C-Pittsburgh compound B results. +1 more finding

    Full summary, score breakdown and related studies → Original source

  22. 2015-03-21

    Fyn inhibition rescues established memory and synapse loss in Alzheimer mice

    ✓ Peer-reviewed Risk genes beyond APOE Annals of neurology

    Key finding: Currently no effective disease-modifying agents exist for the treatment of Alzheimer disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2015-03-20

    Diagnostic accuracy of 123I-meta-iodobenzylguanidine myocardial scintigraphy in dementia with Lewy bodies: a multicenter study

    ✓ Peer-reviewed Cognitive tests and assessment PloS one

    Key finding: Dementia with Lewy bodies (DLB) needs to be distinguished from Alzheimer's disease (AD) because of important differences in patient management and outcome. +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2015-03-20

    Glucocerebrosidase and Parkinson disease: Recent advances

    ✓ Peer-reviewed Caregiving Molecular and cellular neurosciences

    Key finding: Homozygous GBA mutations result in Gaucher disease (GD), a lysosomal storage disorder. +4 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2015-03-19

    First administration of the Fc-attenuated anti-β amyloid antibody GSK933776 to patients with mild Alzheimer's disease: a randomized, placebo-controlled study

    ✓ Peer-reviewed Treatments PloS one

    Key finding: In this FTIH study the Fc-inactivated anti-Aβ mAb GSK933776 engaged its target in plasma and CSF without causing brain ARIA-E/H in patients with mild AD or MCI.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →