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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 17,351–17,375 of 27,380 studies, newest first · page 695 of 1096.

January 2015 25

  1. 2015 year only

    Matrix Metalloproteinases in Alzheimer's Disease and Concurrent Cerebral Microbleeds

    ✓ Peer-reviewed Tau biomarkers Journal of Alzheimer's disease : JAD

    Key finding: AD patients showed higher plasma MMP2 levels compared to VaD patients (p < 0.05), and higher CSF MMP10 levels compared to controls (p < 0.05). +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2015 year only

    Progranulin and Amyloid-β Levels: Relationship to Neuropsychology in Frontotemporal and Alzheimer's Disease

    ✓ Peer-reviewed Tau biomarkers Journal of Alzheimer's disease : JAD

    Key finding: For all patients across both groups, an association between PGRN and categoric (p = 0.016) and letter fluency (p = 0.029), naming (p = 0.003), and overall cognition (Mini-Mental State Examination: p = 0.04) was observed. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2015 year only

    A Novel Plasma Based Biomarker of Alzheimer's Disease

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: In the current study, levels of the previously described novel cerebrospinal fluid aberrant protein complex composed of prostaglandin-D-synthase (PDS) and transthyretin (TTR) were quantified in plasma by a custom two-probe sandwich ELISA and compared to amyloid-β (Aβ)(1-42) as a standard plasma biomarker of AD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2015-01-01

    Three-dimensional brain-on-a-chip with an interstitial level of flow and its application as an in vitro model of Alzheimer's disease

    ✓ Peer-reviewed Digital health tools Lab on a chip

    Key finding: Amyloid-β treatment via an osmotic micropump significantly reduced the viability of neurospheroids and caused a significantly more destruction of neural networks, compared to the amyloid-β treatment under static conditions.

    Full summary, score breakdown and related studies → Original source

  5. 2015-01-01

    Epidemiological and economic burden of Alzheimer's disease: a systematic literature review of data across Europe and the United States of America

    ✓ Peer-reviewed Costs and economics Journal of Alzheimer's disease : JAD

    Key finding: This review corroborates previous understanding that AD burden is high for both society and healthcare providers. +3 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2015-01-01

    Barriers to Optimising Prescribing and Deprescribing in Older Adults with Dementia: A Narrative Review

    ✓ Peer-reviewed End-of-life care Current clinical pharmacology

    Key finding: The aim of this narrative review was to explore barriers to optimising prescribing and deprescribing (withdrawing) of medications as the goal of care shifts from prolonging life to optimising quality of life. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2015-01-01

    The microbiome and disease: reviewing the links between the oral microbiome, aging, and Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms Journal of Alzheimer's disease : JAD

    Key finding: Immunosenescence results in increased bacterial load as cell-mediated and humoral immune responses wane. +2 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2015-01-01

    Decreases in Short Term Memory, IQ, and Altered Brain Metabolic Ratios in Urban Apolipoprotein ε4 Children Exposed to Air Pollution

    ✓ Peer-reviewed Risk factors Journal of Alzheimer's disease : JAD

    Key finding: Children's urban air pollution exposures result in systemic and brain inflammation and the early hallmarks of Alzheimer's disease (AD). +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2015-01-01

    Air pollution and children: neural and tight junction antibodies and combustion metals, the role of barrier breakdown and brain immunity in neurodegeneration

    ✓ Peer-reviewed Risk factors Journal of Alzheimer's disease : JAD

    Key finding: We investigated serum and cerebrospinal fluid (CSF) antibodies to neural and tight junction proteins and environmental pollutants in 139 children ages 11.91 ± 4.2 y with high versus low air pollution exposures. +2 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2015-01-01

    Role of environmental contaminants in the etiology of Alzheimer's disease: a review

    ✓ Peer-reviewed Risk factors Current Alzheimer research

    Key finding: However, many in vitro and animal studies have identified toxic effects of environmental contaminants at the cellular level, revealing alterations of pathways and metabolisms associated with AD that warrant further investigations.

    Full summary, score breakdown and related studies → Original source

  11. 2015-01-01

    Ozone, particulate matter, and newly diagnosed Alzheimer's disease: a population-based cohort study in Taiwan

    ✓ Peer-reviewed Risk factors Journal of Alzheimer's disease : JAD

    Key finding: The adjusted HR for AD was weakly associated with a raised concentration in O3 at baseline per increase of 9.63 ppb (adjusted HR 1.06, 95% confidence interval (CI) 1.00-1.12). +2 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2015-01-01

    Recent development of multifunctional agents as potential drug candidates for the treatment of Alzheimer's disease

    ✓ Peer-reviewed Treatments Current medicinal chemistry

    Key finding: The majority of the recently reported structures are acetylcholinesterase inhibitors, often endowed with some additional properties. +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2015-01-01

    The GLP-1 Receptor Agonist Liraglutide Improves Memory Function and Increases Hippocampal CA1 Neuronal Numbers in a Senescence-Accelerated Mouse Model of Alzheimer's Disease

    ✓ Peer-reviewed Drug development Journal of Alzheimer's disease : JAD

    Key finding: Recent studies indicate that glucagon-like peptide 1 (GLP-1) receptor agonists, currently used in the management of type 2 diabetes, exhibit neurotrophic and neuroprotective effects in amyloid-β (Aβ) toxicity models of Alzheimer's disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2015-01-01

    New developments of clinical trial in immunotherapy for Alzheimer's disease

    ✓ Peer-reviewed Treatments Current pharmaceutical biotechnology

    Key finding: Immunotherapy for AD has demonstrated that targeting beta-amyloid (Aβ) or tau protein with vaccines or antibodies can reduce AD pathologies. +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2015-01-01

    Spontaneous ARIA (amyloid-related imaging abnormalities) and cerebral amyloid angiopathy related inflammation in presenilin 1-associated familial Alzheimer's disease

    ✓ Peer-reviewed Treatments Journal of Alzheimer's disease : JAD

    Key finding: Amyloid-related imaging abnormalities (ARIA), thought to reflect immune responses to vascular amyloid, have been detected in several amyloid-modifying therapy trials for Alzheimer's disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2015-01-01

    Prodromal Alzheimer's disease presenting as cerebral amyloid angiopathy-related inflammation with spontaneous amyloid-related imaging abnormalities and high cerebrospinal fluid anti-Aβ autoantibodies

    ✓ Peer-reviewed Treatments Journal of Alzheimer's disease : JAD

    Key finding: Cerebral amyloid angiopathy-related inflammation (CAA-ri), a rare form of vasculitis associated with amyloid-β (Aβ) deposition in vessel walls, has been proposed as a spontaneous human model of the amyloid-related imaging abnormalities (ARIA) occurring after anti-Aβ immunotherapy for the treatment of Alzheimer's disease (AD).

    Full summary, score breakdown and related studies → Original source

  17. 2015-01-01

    The potent BACE1 inhibitor LY2886721 elicits robust central Aβ pharmacodynamic responses in mice, dogs, and humans

    ✓ Peer-reviewed Treatments The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: BACE1 is a key protease controlling the formation of amyloid β, a peptide hypothesized to play a significant role in the pathogenesis of Alzheimer's disease (AD).

    Full summary, score breakdown and related studies → Original source

  18. 2015-01-01

    Retinal ganglion cell analysis using high-definition optical coherence tomography in patients with mild cognitive impairment and Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging Journal of Alzheimer's disease : JAD

    Key finding: Our data strengthens the link between retinal ganglion cell neuronal and optic nerve axonal loss with AD, and suggest that assessment of macular GC-IPL can be a test to detect neuronal injury in early AD and MCI. +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2015-01-01

    Mechanisms of molecular mimicry involving the microbiota in neurodegeneration

    ✓ Peer-reviewed Genetics Journal of Alzheimer's disease : JAD

    Key finding: Cross-seeding of amyloid misfolding, altered proteostasis, and oxidative stress may be induced by amyloid proteins residing in bacteria in our microbiota in the gut and in the diet. +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2015-01-01

    Wilson's disease and other neurological copper disorders

    ✓ Peer-reviewed Risk genes beyond APOE The Lancet. Neurology

    Key finding: Direct genetic testing for ATP7B mutations are increasingly available to confirm the clinical diagnosis of Wilson's disease, and results from biochemical and genetic prevalence studies suggest that Wilson's disease might be much more common than previously estimated. +1 more finding

    Full summary, score breakdown and related studies → Original source

  21. 2015-01-01

    A phase II trial of tideglusib in Alzheimer's disease

    ✓ Peer-reviewed Tau biomarkers Journal of Alzheimer's disease : JAD

    Key finding: Short term (26 weeks) tideglusib was acceptably safe but produced no clinical benefit in this trial. +3 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2015-01-01

    Blood-brain barrier breakdown in the aging human hippocampus

    ✓ Peer-reviewed Tau biomarkers Neuron

    Key finding: Our data suggest that BBB breakdown is an early event in the aging human brain that begins in the hippocampus and may contribute to cognitive impairment.

    Full summary, score breakdown and related studies → Original source

  23. 2015-01-01

    Fatty acid profiles in demented patients: identification of hexacosanoic acid (C26:0) as a blood lipid biomarker of dementia

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: The variations of fatty acid levels and the accumulation of C26:0 in the plasma and RBCs highlight an alteration of fatty acid metabolism in demented patients and point toward possible peroxisomal dysfunction. +2 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2015-01-01

    Blood Protein Markers of Neocortical Amyloid-β Burden: A Candidate Study Using SOMAscan Technology

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: We have further demonstrated the association of PPY and IgM with NAB, despite technical differences between studies. +2 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2015-01-01

    Amyloid-β 42/40 cerebrospinal fluid concentration ratio in the diagnostics of Alzheimer's disease: validation of two novel assays

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: (a) the novel Aβ1-40 and Aβ1-42 ELISA assays characterize with very good analytical performance; (b) we reconfirm that the CSF Aβ42/40 concentration ratio shows significantly better diagnostic performance compared to the CSF Aβ1-42 concentration alone. +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →