alzhub.org
Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 15,551–15,575 of 27,380 studies, newest first · page 623 of 1096.

January 2017 2

  1. 2017-01-01

    The Risk of Incident Mild Cognitive Impairment and Progression to Dementia Considering Mild Cognitive Impairment Subtypes

    ✓ Peer-reviewed Genetics Dementia and geriatric cognitive disorders extra

    Key finding: Cognitively normal subjects with an APOE ε4 allele had a higher likelihood of developing aMCI and the MCI subtype was associated with the dementia subtype. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2017-01-01

    A Comparison of the Prevalence of Dementia in the United States in 2000 and 2012

    ✓ Peer-reviewed How common it is JAMA Internal Medicine

    Key finding: Dementia prevalence in US adults 65+ fell from 11.6% (2000) to 8.8% (2012), a statistically significant decline (P<.001) +3 more findings

    Full summary, score breakdown and related studies → Original source

December 2016 23

  1. 2016-12-31

    Treadmill exercise ameliorates symptoms of Alzheimer disease through suppressing microglial activation-induced apoptosis in rats

    ✓ Peer-reviewed Biomarkers Journal of exercise rehabilitation

    Key finding: The present results demonstrated that treadmill exercise ameliorated AD-induced impairments of spatial learning ability and short-term memory through suppressing apoptosis.

    Full summary, score breakdown and related studies → Original source

  2. 2016-12-30

    Natural products against Alzheimer's disease: Pharmaco-therapeutics and biotechnological interventions

    ✓ Peer-reviewed Drug development Biotechnology advances

    Key finding: Alzheimer's disease (AD) is a severe, chronic and progressive neurodegenerative disease associated with memory and cognition impairment ultimately leading to death. +3 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2016-12-30

    Comprehensive and Integrated Palliative Care for People With Advanced Chronic Conditions: An Update From Several European Initiatives and Recommendations for Policy

    ✓ Peer-reviewed End-of-life care Journal of pain and symptom management

    Key finding: There is a great need to identify these patients and integrate an early palliative approach according to their individual needs in all settings, as suggested by the World Health Organization. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2016-12-30

    Continued Use of Warfarin in Veterans with Atrial Fibrillation After Dementia Diagnosis

    ✓ Peer-reviewed Health systems and care delivery Journal of the American Geriatrics Society

    Key finding: After a diagnosis of dementia, 405 individuals (16%) persisted on warfarin therapy. +3 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2016-12-30

    Olfaction and risk of dementia in a biracial cohort of older adults

    ✓ Peer-reviewed Disparities Neurology

    Key finding: Poorer OI in older adults without dementia was associated with increased risk of dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2016-12-29

    End-of-life treatment decisions in nursing home residents dying with dementia in the Netherlands

    ✓ Peer-reviewed End-of-life care International journal of geriatric psychiatry

    Key finding: Physicians often withhold potentially burdensome life-prolonging treatment in nursing home residents in all stages of dementia in the Netherlands. +1 more finding

    Full summary, score breakdown and related studies → Original source

  7. 2016-12-28

    Role of the adhesion molecule F3/Contactin in synaptic plasticity and memory

    ✓ Peer-reviewed Disease mechanisms Molecular and cellular neurosciences

    Key finding: Here, we discuss our recent data suggesting that F3/Contactin exerts a role in hippocampal synaptic plasticity and memory in adult and aged mice. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2016-12-28

    Down syndrome and the complexity of genome dosage imbalance

    ✓ Peer-reviewed Down syndrome and Alzheimer's Nature reviews. Genetics

    Key finding: Down syndrome (also known as trisomy 21) is the model human phenotype for all genomic gain dosage imbalances, including microduplications. +3 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2016-12-27

    Accuracy of Caregiver Proxy Reports of Home Care Service Use

    ✓ Peer-reviewed Health systems and care delivery Journal of applied gerontology : the official journal of the Southern Gerontological Society

    Key finding: The four home care services examined include home nursing care, adult day care, home support, and respite care. +4 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2016-12-26

    Safety and Efficacy of Anti-Amyloid-β Immunotherapy in Alzheimer's Disease: A Systematic Review and Meta-Analysis

    ✓ Peer-reviewed Treatments Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology

    Key finding: Immunotherapeutics targeting amyloid-β (Aβ) have had mixed results in clinical trials. +2 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2016-12-25

    Surface Plasmon Resonance Clinical Biosensors for Medical Diagnostics

    ✓ Peer-reviewed Risk factors ACS Sensors

    Key finding: This Perspective reviews the current status of the field, showcasing a series of early successes in the application of SPR for clinical analysis and detailing a series of considerations regarding sensing schemes, exposing issues with analysis in biofluids, and comparing SPR with ELISA, while providing an outlook of the challenges currently associated with plasmonic materials, instrumentation, microfluidics, bioreceptor selection, selection of a clinical market, and validation of a clinical assay for applying SPR sensors to clinical samples.

    Full summary, score breakdown and related studies → Original source

  12. 2016-12-24

    Benzodiazepine Use and Risk of Dementia in the Elderly Population: A Systematic Review and Meta-Analysis

    ✓ Peer-reviewed Drug development Neuroepidemiology

    Key finding: Key Messages: Our results suggest that benzodiazepine use is significantly associated with dementia risk. +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2016-12-23

    Apathy and intrinsic functional connectivity networks in amnestic mild cognitive impairment

    ✓ Peer-reviewed Brain scans and imaging Neuropsychiatric disease and treatment

    Key finding: We observed that the FCs of the DMN were less and those of CEN were more in the aMCI group than the CON group. +2 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2016-12-23

    Synergistic interaction between amyloid and tau predicts the progression to dementia

    ✓ Peer-reviewed Clinical safety Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: The present results support that progression to AD dementia is driven by the synergistic rather than a mere additive effect between Aβ and p-tau proteins. +2 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2016-12-22

    Drug Repositioning for Alzheimer's Disease Based on Systematic 'omics' Data Mining

    ✓ Peer-reviewed Drug development PloS one

    Key finding: We developed a ranking algorithm to prioritize the anti-AD targets, which revealed CD33 and MIF as the strongest candidates with seven existing drugs.

    Full summary, score breakdown and related studies → Original source

  16. 2016-12-22

    The Ontario Neurodegenerative Disease Research Initiative (ONDRI)

    ✓ Peer-reviewed Digital health tools The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques

    Key finding: Because individuals develop dementia as a manifestation of neurodegenerative or neurovascular disorder, there is a need to develop reliable approaches to their identification. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2016-12-21

    Chicoric acid supplementation prevents systemic inflammation-induced memory impairment and amyloidogenesis via inhibition of NF-κB

    ✓ Peer-reviewed Risk genes beyond APOE FASEB journal : official publication of the Federation of American Societies for Experimental Biology

    Key finding: We investigated the inhibitory effects of CA on systemic inflammation-induced neuroinflammation, amyloidogenesis, and cognitive impairment. +3 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2016-12-21

    Tau-PET uptake: Regional variation in average SUVR and impact of amyloid deposition

    ✓ Peer-reviewed Biomarkers Alzheimer's & dementia (Amsterdam, Netherlands)

    Key finding: Regions with high-average SUVR are not necessarily those with the greatest tau pathology.

    Full summary, score breakdown and related studies → Original source

  19. 2016-12-20

    Dementia Caregivers and Live Discharge from Hospice: What Happens When Hospice Leaves?

    ✓ Peer-reviewed End-of-life care Journal of gerontological social work

    Key finding: Hospice offers holistic support for individuals living with terminal illness and their caregivers. +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2016-12-20

    Computer-Based Cognitive Training in Aging

    ✓ Peer-reviewed Prevention trials Frontiers in aging neuroscience

    Key finding: Furthermore, the results indicate that it is important to pay close attention to the methodological standards in future clinical studies.

    Full summary, score breakdown and related studies → Original source

  21. 2016-12-20

    Neurodegenerative disease mutations in TREM2 reveal a functional surface and distinct loss-of-function mechanisms

    ✓ Peer-reviewed TREM2 and immune genetics eLife

    Key finding: To determine how TREM2 variants contribute to these diseases, we performed structural and functional studies of wild-type and variant proteins. +3 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2016-12-19

    Emerging ocular biomarkers of Alzheimer disease

    ✓ Peer-reviewed Brain scans and imaging Clinical & experimental ophthalmology

    Key finding: Interest in reliable biomarkers of Alzheimer disease, the leading cause of dementia, has been fuelled by challenges in diagnosing the disease and monitoring disease progression as well as the response to therapy. +2 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2016-12-19

    AV-1451 tau and β-amyloid positron emission tomography imaging in dementia with Lewy bodies

    ✓ Peer-reviewed Brain scans and imaging Annals of neurology

    Key finding: Medial temporal lobe AV-1451 uptake distinguishes AD dementia from probable DLB, which may be useful for differential diagnosis. +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →