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No Association between Dietary Patterns and Risk for Cognitive Decline in Older Women with 9-Year Follow-Up: Data from the Women's Health Initiative Memory Study
Haring B, Wu C, Mossavar-Rahmani Y, Snetselaar L, Brunner R, Wallace RB, Neuhouser ML, Wassertheil-Smoller S.. Journal of the Academy of Nutrition and Dietetics, 2016-03-31
Topic: Risk, prevention and care in population studies
Background Data on the association between dietary patterns and age-related cognitive decline are inconsistent. Objective To determine whether dietary patterns assessed by the alternate Mediterranean diet score (aMED), the Healthy Eating Index-2010 (HEI-2010), the Alternate Healthy Eating Index 2010 (AHEI-2010), or the Dietary Approach to Stop Hypertension (DASH) diet score are associated with cognitive decline in older women, and to examine whether dietary patterns modify the risk for cognitive decline in women with hypertension. Design Prospective, longitudinal cohort study. Food frequency questionnaires were used to derive dietary patterns at baseline. Hypertension was defined as self-report of current drug therapy for hypertension or clinic measurement of systolic blood pressure ≥140 mm Hg or diastolic blood pressure ≥90 mm Hg. Participants and setting Postmenopausal women (N=6,425) aged 65 to 79 years who participated in the Women's Health Initiative Memory Study and were cognitively intact at baseline. Main outcome measures Cognitive decline was defined as cases of mild cognitive impairment (MCI) or probable dementia (PD). Cases were identified through rigorous screening and expert adjudication. Statistical analyses performed Cox proportional hazards models with multivariable adjustment were used to estimate the relative risk for developing MCI or PD. Results During a median follow-up of 9.11 years, we documented 499 cases of MCI and 390 of PD. In multivariable analyses we did not detect any statistically significant relationships across quintiles of aMED, HEI-2010, DASH, and AHEI-2010 scores and MCI or PD (P values for trend=0.30, 0.44, 0.23, and 0.45). In women with hypertension, we found no significant association between dietary patterns and cognitive decline (P values for trend=0.19, 0.08, 0.07, and 0.60). Conclusions Dietary patterns characterized by the aMED, HEI-2010, AHEI-2010, or DASH dietary score were not associated with cognitive decline in older women. Adherence to a healthy dietary pattern did not modify the risk for cognitive decline in women with hypertension.
Key findings
- Objective To determine whether dietary patterns assessed by the alternate Mediterranean diet score (aMED), the Healthy Eating Index-2010 (HEI-2010), the Alternate Healthy Eating Index 2010 (AHEI-2010), or the Dietary Approach to Stop Hypertension (DASH) diet score are associated with cognitive decline in older women, and to examine whether dietary patterns modify the risk for cognitive decline in women with hypertension.
- Results During a median follow-up of 9.11 years, we documented 499 cases of MCI and 390 of PD.
- In multivariable analyses we did not detect any statistically significant relationships across quintiles of aMED, HEI-2010, DASH, and AHEI-2010 scores and MCI or PD (P values for trend=0.30, 0.44, 0.23, and 0.45).
- In women with hypertension, we found no significant association between dietary patterns and cognitive decline (P values for trend=0.19, 0.08, 0.07, and 0.60).
- Conclusions Dietary patterns characterized by the aMED, HEI-2010, AHEI-2010, or DASH dietary score were not associated with cognitive decline in older women.
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Study details
- Study designcohort study
- Participants6,425
- Evidence strengthModerate
How this study scored 62/100
Published in a peer-reviewed journal, and it is a cohort study following people over time. Scored zero for effect reported and randomised / blinded because the record does not state it. We have no data on journal's citation record, times cited, citations per year, impact for its field and year, cited by studies here, still being cited, senior author's track record, institution's track record and multi-centre collaboration, so those were left out: it earned 36 of the 58 points we could judge it on, which is 62 out of 100.
| Component | Points | Why |
|---|---|---|
| Journal tier | 7 / 10 | Tier 3 — peer-reviewed journal (Journal of the Academy of Nutrition and Dietetics) |
| Journal's citation record | — / 4 | No journal record from OpenAlex — left out of this score |
| Study design | 7 / 12 | A cohort study following people over time |
| Strength of evidence | 3 / 5 | Rated “moderate” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 1 / 5 | 2016 — within 20 year(s) of the newest study here |
| Sample size | 3 / 4 | 6,425 participants |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | — / 7 | No citation count (not found in OpenAlex) — left out of this score |
| Citations per year | — / 5 | No citation count or no year — left out of this score |
| Impact for its field and year | — / 6 | No field-weighted citation impact (OpenAlex has none yet) — left out of this score |
| Cited by studies here | — / 6 | Not yet checked against this library's citation graph — left out of this score |
| Still being cited | — / 4 | No yearly citation counts — left out of this score |
| Senior author's track record | — / 4 | Senior author's record not available — left out of this score |
| Institution's track record | — / 3 | No institution listed in OpenAlex — left out of this score |
| Multi-centre collaboration | — / 3 | Institutions not listed — left out of this score |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 27050728) |
| Free to read | 0 / 2 | Behind a paywall — scores zero |
| Points | 36 / 58 | Scored on 11 of 20 parts. We have no data for the rest, so they are left out: 36 of the 58 points we could judge it on is 62 out of 100. |
| Total | 62 / 100 | — |
What each of these 20 components measures, and what this score is not →
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Cite this study APA, Vancouver, BibTeX · download .bib or .ris
Built from the record alzhub holds for this paper, not looked up. Volume, issue and page numbers are not held in the record. The record names 8 authors; APA and Vancouver show the first six, BibTeX and the downloads carry all of them. Check the citation against the original before you use it.
APA 7th
Haring, B., Wu, C., Mossavar-Rahmani, Y., Snetselaar, L., Brunner, R., Wallace, R. B., et al. (2016). No Association between Dietary Patterns and Risk for Cognitive Decline in Older Women with 9-Year Follow-Up: Data from the Women's Health Initiative Memory Study. Journal of the Academy of Nutrition and Dietetics. https://doi.org/10.1016/j.jand.2015.12.017
Vancouver
Haring B, Wu C, Mossavar-Rahmani Y, Snetselaar L, Brunner R, Wallace RB, et al. No Association between Dietary Patterns and Risk for Cognitive Decline in Older Women with 9-Year Follow-Up: Data from the Women's Health Initiative Memory Study. Journal of the Academy of Nutrition and Dietetics. 2016. doi:10.1016/j.jand.2015.12.017. PMID: 27050728.
BibTeX
@article{haring2016-27050728,
author = {Haring, B. and Wu, C. and Mossavar-Rahmani, Y. and Snetselaar, L. and Brunner, R. and Wallace, R. B. and Neuhouser, M. L. and Wassertheil-Smoller, S.},
title = {{No Association between Dietary Patterns and Risk for Cognitive Decline in Older Women with 9-Year Follow-Up: Data from the Women's Health Initiative Memory Study}},
journal = {Journal of the Academy of Nutrition and Dietetics},
year = {2016},
doi = {10.1016/j.jand.2015.12.017},
pmid = {27050728},
url = {https://doi.org/10.1016/j.jand.2015.12.017}
}
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