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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 15,376–15,400 of 27,380 studies, newest first · page 616 of 1096.

January 2017 25

  1. 2017-01-31

    Increase of TREM2 during Aging of an Alzheimer's Disease Mouse Model Is Paralleled by Microglial Activation and Amyloidosis

    ✓ Peer-reviewed TREM2 and immune genetics Frontiers in aging neuroscience

    Key finding: Since TREM2 is specifically expressed by microglia in the brain, we hypothesized that soluble TREM2 (sTREM2) levels may increase together with in vivo biomarkers of microglial activity and amyloidosis in an AD mouse model as assessed by small animal positron-emission-tomography (μPET). +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2017-01-31

    Optimizing Neuropsychological Assessments for Cognitive, Behavioral, and Functional Impairment Classification: A Machine Learning Study

    ✓ Peer-reviewed Digital health tools Behavioural neurology

    Key finding: Our findings show that some tests are more frequently best predictors for the automatic classification, namely, LM, ADAS-Cog, AVLT, and FAQ, with a major role of the ADAS-Cog measures of delayed and immediate memory and the FAQ measure of financial competency.

    Full summary, score breakdown and related studies → Original source

  3. 2017-01-31

    Particulate air pollutants, APOE alleles and their contributions to cognitive impairment in older women and to amyloidogenesis in experimental models

    ✓ Peer-reviewed How common it is Translational psychiatry

    Key finding: We suggest that airborne PM exposure promotes pathological brain aging in older women, with potentially a greater impact in ɛ4 carriers.

    Full summary, score breakdown and related studies → Original source

  4. 2017-01-30

    Pathogenic PS1 phosphorylation at Ser367

    ✓ Peer-reviewed Biomarkers eLife

    Key finding: The high levels of serine (S) and threonine (T) residues within the Presenilin 1 (PS1) N-terminus and in the large hydrophilic loop region suggest that the enzymatic function of PS1/γ-secretase can be modulated by its 'phosphorylated' and 'dephosphorylated' states.

    Full summary, score breakdown and related studies → Original source

  5. 2017-01-27

    Late-Life Depression, Hippocampal Volumes, and Hypothalamic-Pituitary-Adrenal Axis Regulation: A Systematic Review and Meta-analysis

    ✓ Peer-reviewed Hippocampus size on brain scans Biological psychiatry

    Key finding: Relative to control subjects, patients had significantly smaller HCVs (standardized mean difference = -0.32 [95% confidence interval, -0.44 to -0.19]). +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2017-01-27

    Frontotemporal dementia with the V337M MAPT mutation: Tau-PET and pathology correlations

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: Our study supports the usefulness of [ 18 F]AV1451 to characterize tau pathology in at least a subset of pathogenic MAPT mutations. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2017-01-26

    Variation in use of antipsychotic medications in nursing homes in the United States: A systematic review

    ✓ Peer-reviewed Disparities BMC geriatrics

    Key finding: Variation in use of APMs in U.S. nursing homes based upon facility characteristics exemplifies the need for a more systematic protocol guiding the use of these medications, along with heightened regulatory policies and enforcement. +1 more finding

    Full summary, score breakdown and related studies → Original source

  8. 2017-01-26

    Cognitive Decline and Its Risk Factors in Prevalent Hemodialysis Patients

    ✓ Peer-reviewed Disparities American journal of kidney diseases : the official journal of the National Kidney Foundation

    Key finding: Prevalent hemodialysis patients demonstrate significant cognitive decline, particularly within tests of executive function. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2017-01-26

    Comprehensive, Individualized, Person-Centered Management of Community-Residing Persons with Moderate-to-Severe Alzheimer Disease: A Randomized Controlled Trial

    ✓ Peer-reviewed Treatments Dementia and geriatric cognitive disorders

    Key finding: These results are approximately 10 times those usually observed with both nonpharmacological and pharmacological treatments and indicate substantial benefits with the management program for advanced AD persons. +2 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2017-01-25

    Retinal thickness in Alzheimer's disease: A systematic review and meta-analysis

    ✓ Peer-reviewed Brain scans and imaging Alzheimer's & dementia (Amsterdam, Netherlands)

    Key finding: Retinal thickness is decreased in AD and MCI patients compared to HC. +1 more finding

    Full summary, score breakdown and related studies → Original source

  11. 2017-01-24

    Deep ensemble learning of sparse regression models for brain disease diagnosis

    ✓ Peer-reviewed Digital health tools Medical image analysis

    Key finding: We also rigorously analyzed our results and compared with the previous studies on the ADNI cohort in the literature.

    Full summary, score breakdown and related studies → Original source

  12. 2017-01-23

    Systemic inflammation and resting state connectivity of the default mode network

    ✓ Peer-reviewed Brain scans and imaging Brain, behavior, and immunity

    Key finding: Accordingly, we tested whether plasma interleukin (IL)-6, an indicator of systemic inflammation, covaried with resting-state functional connectivity of the DMN among 98 adults aged 30-54 (39% male; 81% Caucasian). +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2017-01-23

    Alzheimer's biomarkers in daily practice (ABIDE) project: Rationale and design

    ✓ Peer-reviewed Brain scans and imaging Alzheimer's & dementia (Amsterdam, Netherlands)

    Key finding: Based on retrospective data, we develop personalized risk estimates for MCI patients. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2017-01-23

    Endo-lysosomal and autophagic dysfunction: a driving factor in Alzheimer's disease?

    ✓ Peer-reviewed Clinical safety Journal of neurochemistry

    Key finding: Alzheimer's disease (AD) is the most common cause of dementia, and its prevalence will increase significantly in the coming decades.

    Full summary, score breakdown and related studies → Original source

  15. 2017-01-23

    Quantitative EEG (QEEG) Measures Differentiate Parkinson's Disease (PD) Patients from Healthy Controls (HC)

    ✓ Peer-reviewed Digital health tools Frontiers in aging neuroscience

    Key finding: Random Forest and LASSO were found to be optimal methods for feature selection. +3 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2017-01-21

    Locus coeruleus cellular and molecular pathology during the progression of Alzheimer's disease

    ✓ Peer-reviewed Mild cognitive impairment Acta neuropathologica communications

    Key finding: Stereologic estimates of total LC neuron number revealed a 30% loss during the transition from NCI to aMCI, with an additional 25% loss of LC neurons in AD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2017-01-20

    Effects of pioglitazone on the incidence of dementia in patients with diabetes

    ✓ Peer-reviewed Digital health tools Journal of diabetes and its complications

    Key finding: Pioglitazone is a time- and dose-dependent protective factor against dementia in patients with diabetes. +1 more finding

    Full summary, score breakdown and related studies → Original source

  18. 2017-01-20

    A novel mutation in TREM2 gene causing Nasu-Hakola disease and review of the literature

    ✓ Peer-reviewed TREM2 and immune genetics Neurobiology of aging

    Key finding: NHD may be the prototype of primary microglial disorders of the CNS or, as they have been coined, "microgliopathies". +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2017-01-20

    Natural course of mild cognitive impairment in Parkinson disease: A 5-year population-based study

    ✓ Peer-reviewed Mild cognitive impairment Neurology

    Key finding: Early PD-MCI, regardless of persistence or reversion to normal cognition, has prognostic value for predicting dementia in patients with PD. +1 more finding

    Full summary, score breakdown and related studies → Original source

  20. 2017-01-20

    Clinical practice with anti-dementia drugs: A revised (third) consensus statement from the British Association for Psychopharmacology

    ✓ Peer-reviewed Prevention and risk Journal of psychopharmacology (Oxford, England)

    Key finding: Though results of pivotal studies in early (prodromal/mild) Alzheimer's disease are awaited, results to date in more established (mild to moderate) Alzheimer's disease have been equivocal and no disease modifying agents are either licensed or can be currently recommended for clinical use.

    Full summary, score breakdown and related studies → Original source

  21. 2017-01-20

    TOMM40'523 variant and cognitive decline in older persons with APOE ε3/3 genotype

    ✓ Peer-reviewed Genetics Neurology

    Key finding: Our data reveal an association of APOE ε3/3- TOMM40 '523 haplotypes with cognitive decline in community-based older persons such that the S/S poly-T genotype is related to faster cognitive decline, primarily in the domains of episodic and semantic memory.

    Full summary, score breakdown and related studies → Original source

  22. 2017-01-19

    Multimodal Neuroimaging Feature Learning With Multimodal Stacked Deep Polynomial Networks for Diagnosis of Alzheimer's Disease

    ✓ Peer-reviewed Digital health tools IEEE journal of biomedical and health informatics

    Key finding: Experimental results indicate that MM-SDPN is superior over the state-of-the-art multimodal feature-learning-based algorithms for AD diagnosis.

    Full summary, score breakdown and related studies → Original source

  23. 2017-01-19

    ApoE2, ApoE3, and ApoE4 Differentially Stimulate APP Transcription and Aβ Secretion

    ✓ Peer-reviewed Genetics Cell

    Key finding: Using ES-cell-derived human neurons, we show that ApoE secreted by glia stimulates neuronal Aβ production with an ApoE4 > ApoE3 > ApoE2 potency rank order. +4 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2017-01-19

    Exploring healthcare assistants' role and experience in pain assessment and management for people with advanced dementia towards the end of life: a qualitative study

    ✓ Peer-reviewed End-of-life care BMC palliative care

    Key finding: Healthcare assistants are frontline staff who have a key role in direct patient care, spending a considerable amount of time with patients in comparison to other health professionals.

    Full summary, score breakdown and related studies → Original source

  25. 2017-01-18

    Novel genetic loci associated with hippocampal volume

    ✓ Peer-reviewed Hippocampus size on brain scans Nature communications

    Key finding: To identify the genetic underpinnings of hippocampal structure here we perform a genome-wide association study (GWAS) of 33,536 individuals and discover six independent loci significantly associated with hippocampal volume, four of them novel. +2 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →