Newest studies
Every summary in our library, newest first, as a dated timeline.
Showing 16,001–16,025 of 27,380 studies, newest first · page 641 of 1096.
June 2016 25
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2016-06-15
Physiological functions and pathobiology of TDP-43 and FUS/TLS proteins
49/100 ✓ Peer-reviewed Lewy body dementia Journal of neurochemistry
Key finding: The two major RNA Binding Proteins involved in Amyotrophic Lateral Sclerosisi and Frontotemporal Dementia are TDP-43 and FUST/TLS. +4 more findings
Full summary, score breakdown and related studies → Original source
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2016-06-14
Blood cadmium levels and Alzheimer's disease mortality risk in older US adults
50/100 ✓ Peer-reviewed Risk factors Environmental health : a global access science source
Key finding: We observed a significant association between blood cadmium levels and AD mortality among older adults in the US. +4 more findings
Full summary, score breakdown and related studies → Original source
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2016-06-14
Pain in Hospice Patients With Dementia: The Informal Caregiver Experience
36/100 ✓ Peer-reviewed End-of-life care American journal of Alzheimer's disease and other dementias
Key finding: Our findings indicate the possible need for increased support for caregivers, including educational interventions targeting pain etiology and assessment, and improved communication with health-care professionals. +1 more finding
Full summary, score breakdown and related studies → Original source
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2016-06-14
Relation of cerebral vessel disease to Alzheimer's disease dementia and cognitive function in elderly people: a cross-sectional study
69/100 ✓ Peer-reviewed How common it is The Lancet. Neurology
Key finding: Each level increase in the severity of atherosclerosis or arteriolosclerosis was associated with significantly higher odds of Alzheimer's disease dementia (odds ratio [OR] for atherosclerosis 1·33, 95% CI 1·11-1·58; OR for arteriolosclerosis 1·20, 1·04-1·40). +3 more findings
Full summary, score breakdown and related studies → Original source
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2016-06-13
An autoradiographic evaluation of AV-1451 Tau PET in dementia
57/100 ✓ Peer-reviewed Brain scans and imaging Acta neuropathologica communications
Key finding: Reduced AV-1451 binding in neuritic pathology compared to neurofibrillary tangles suggests that the maturity of tau pathology may affect AV-1451 binding and suggests complexity in AV-1451 binding. +3 more findings
Full summary, score breakdown and related studies → Original source
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2016-06-10
Home-based caregiver training: Benefits differ by care receivers' dementia diagnosis
71/100 ✓ Peer-reviewed Caregiving Geriatric nursing (New York, N.Y.)
Key finding: Our sub-sample comprised patient-caregiver dyads (46 VaD and 68 AD patients) followed for 18 months. +4 more findings
Full summary, score breakdown and related studies → Original source
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2016-06-10
Medicare and Amyloid PET Imaging: The Battle Over Evidence
39/100 ✓ Peer-reviewed Brain scans and imaging Journal of aging & social policy
Key finding: We examine a recent dispute regarding the Centers for Medicare and Medicaid Services' (CMS) refusal to unconditionally pay for amyloid positron emission tomography (PET) imaging for Medicare beneficiaries being assessed for Alzheimer's disease. +2 more findings
Full summary, score breakdown and related studies → Original source
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2016-06-10
Healthy Ageing Through Internet Counselling in the Elderly: the HATICE randomised controlled trial for the prevention of cardiovascular disease and cognitive impairment
74/100 ✓ Peer-reviewed Prevention trials BMJ open
Key finding: Recruitment of 2600 older people (≥65 years) at increased risk of cardiovascular disease will take place in the Netherlands, Finland and France. +1 more finding
Full summary, score breakdown and related studies → Original source
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2016-06-10
The relationship between cerebrospinal fluid markers of Alzheimer pathology and positron emission tomography tau imaging
53/100 ✓ Peer-reviewed Tau biomarkers Brain : a journal of neurology
Key finding: Investigations into these pathologies have been restricted to cerebrospinal fluid assays, and positron emission tomography tracers that can image amyloid-β plaques. +3 more findings
Full summary, score breakdown and related studies → Original source
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2016-06-09
Apolipoprotein E: from cardiovascular disease to neurodegenerative disorders
38/100 ✓ Peer-reviewed Genetics Journal of molecular medicine (Berlin, Germany)
Key finding: ApoE4 likely causes neurodegeneration secondary to its abnormal structure, caused by an interaction between its carboxyl- and amino-terminal domains, called domain interaction. +4 more findings
Full summary, score breakdown and related studies → Original source
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2016-06-09
Neurofilament Light Chain in Blood and CSF as Marker of Disease Progression in Mouse Models and in Neurodegenerative Diseases
36/100 ✓ Peer-reviewed Biomarkers Neuron
Key finding: We found robust increases of neurofilament light chain (NfL) in CSF and blood in murine models of α-synucleinopathies, tauopathy, and β-amyloidosis. +1 more finding
Full summary, score breakdown and related studies → Original source
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2016-06-09
Argyrophilic Grain Disease: Demographics, Clinical, and Neuropathological Features From a Large Autopsy Study
52/100 ✓ Peer-reviewed Disease mechanisms Journal of neuropathology and experimental neurology
Key finding: AGD was associated with older age, lower socioeconomic status (SES), and appetite disorders. +1 more finding
Full summary, score breakdown and related studies → Original source
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2016-06-09
Perceptions of dementia and use of services in minority ethnic communities: a scoping exercise
40/100 ✓ Peer-reviewed Disparities Health & social care in the community
Key finding: The findings suggest that although groups attributed a biological basis for memory loss, a number of misconceptions prevailed regarding the cause of dementia.
Full summary, score breakdown and related studies → Original source
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2016-06-08
Development of an ultra-high sensitive immunoassay with plasma biomarker for differentiating Parkinson disease dementia from Parkinson disease using antibody functionalized magnetic nanoparticles
40/100 ✓ Peer-reviewed Biomarkers Journal of nanobiotechnology
Key finding: The ultra-sensitive IMR by utilizing antibody-functionalized magnetic nanoparticles and high-Tc SQUID magnetometer is promising as a method to assay plasma α-synuclein, which is a potential biomarker for discriminating patients with PD or PDD. +2 more findings
Full summary, score breakdown and related studies → Original source
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2016-06-07
Potential neuroprotective properties of epigallocatechin-3-gallate (EGCG)
40/100 ✓ Peer-reviewed Costs and economics Nutrition journal
Key finding: In a hope for cure, these diseases have been studied extensively over the last decade to successfully develop symptom-oriented therapies. +4 more findings
Full summary, score breakdown and related studies → Original source
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2016-06-07
Fidelity to a behavioral intervention to improve goals of care decisions for nursing home residents with advanced dementia
72/100 ✓ Peer-reviewed End-of-life care Clinical trials (London, England)
Key finding: The methods we used for intervention fidelity allowed nursing home staff to implement a goals of care decision aid intervention for advanced dementia.
Full summary, score breakdown and related studies → Original source
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2016-06-06
Appetite and Weight Loss Symptoms in Late-Life Depression Predict Dementia Outcomes
50/100 ✓ Peer-reviewed Risk factors The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry
Key finding: Higher scores on the appetite and weight loss symptom factor were associated with an increased hazard of both AD and non-AD dementia. +4 more findings
Full summary, score breakdown and related studies → Original source
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2016-06-06
The care needs and experiences with the use of services of people with young-onset dementia and their caregivers: a systematic review
57/100 ✓ Peer-reviewed Costs and economics International journal of geriatric psychiatry
Key finding: The literature indicates that people with YOD and their caregivers face a wide range of difficulties during the disease process. +2 more findings
Full summary, score breakdown and related studies → Original source
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2016-06-06
Prevalence of Artificial Food Colors in Grocery Store Products Marketed to Children
36/100 ✓ Peer-reviewed Risk factors Clinical Pediatrics
Key finding: Overall, 350 products (43.2%) contained AFCs.
Full summary, score breakdown and related studies → Original source
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2016-06-03
Exercise for Individuals with Lewy Body Dementia: A Systematic Review
77/100 ✓ Peer-reviewed Prevention trials PloS one
Key finding: 111,485 articles were initially retrieved; 288 full articles were reviewed and 89.6% subsequently deemed ineligible due to exclusion of participants with co-existence of dementia and Parkinsonism. +4 more findings
Full summary, score breakdown and related studies → Original source
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2016-06-03
DYRK1A, a Dosage-Sensitive Gene Involved in Neurodevelopmental Disorders, Is a Target for Drug Development in Down Syndrome
40/100 ✓ Peer-reviewed Down syndrome and Alzheimer's Frontiers in behavioral neuroscience
Key finding: DYRK1A is a dual-specificity kinase that is overexpressed in DS and plays a key role in neurogenesis, outgrowth of axons and dendrites, neuronal trafficking and aging. +4 more findings
Full summary, score breakdown and related studies → Original source
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2016-06-02
Microglial immunophenotype in dementia with Alzheimer's pathology
55/100 ✓ Peer-reviewed Inflammation and the immune system Journal of neuroinflammation
Key finding: Genetic risk factors for Alzheimer's disease imply that inflammation plays a causal role in development of the disease. +3 more findings
Full summary, score breakdown and related studies → Original source
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2016-06-02
(1)H-MRS metabolites in adults with Down syndrome: Effects of dementia
53/100 ✓ Peer-reviewed Down syndrome and Alzheimer's NeuroImage. Clinical
Key finding: We evaluated associations between (1)H-MRS results and cognition among DS participants. +4 more findings
Full summary, score breakdown and related studies → Original source
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2016-06 month only
End-of-life care in a psychiatric hospital
38/100 ✓ Peer-reviewed End-of-life care BJPsych bulletin
Key finding: It is becoming more important for different services to provide long-term palliative care for patients with dementia. +4 more findings
Full summary, score breakdown and related studies → Original source
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2016-06-01
Defining Safety in the Nursing Home Setting: Implications for Future Research
38/100 ✓ Peer-reviewed Health systems and care delivery Journal of the American Medical Directors Association
Key finding: Future research needs include expanding our definition of safety in the NH setting, which differs considerably from that of hospitals, to include contributing factors to adverse events as well as more resident-centered care measures. +4 more findings
Full summary, score breakdown and related studies → Original source
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