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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 2,876–2,900 of 27,380 studies, newest first · page 116 of 1096.

October 2025 25

  1. 2025-10-22

    Incretin-Based Drugs and the Risk of Dementia Among Patients with Type 2 Diabetes

    ✓ Peer-reviewed Drug development Drug safety

    Key finding: Among 275,144 initiators of DPP-4 inhibitors or sulfonylureas, followed for 750,846 person-years, DPP-4 inhibitors were associated with a reduced dementia risk compared with sulfonylureas (4.4 vs. 5.7 events per 1000 person-years; HR 0.77, 95% CI 0.71-0.85). +4 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2025-10-22

    Quantifying subpercent nuclear TDP ‐43 loss in cells and ALS cortex using junction‐specific cryptic exon RT ‐ qPCR

    ✓ Peer-reviewed Brain tissue and pathology FEBS Letters

    Key finding: Crucially, the assay revealed a 42-fold CE increase in ALS motor cortex, previously missed by conventional primers.

    Full summary, score breakdown and related studies → Original source

  3. 2025-10-22

    The connection between autophagy and Alzheimer’s disease

    ✓ Peer-reviewed Risk genes beyond APOE Inflammation Research

    Key finding: Alzheimer's disease (AD) is the most prevalent neurodegenerative disease associated with accumulation of amyloid beta peptides and intracellular neurofibrillary tangles formed by hyperphosphorylated Tau.

    Full summary, score breakdown and related studies → Original source

  4. 2025-10-22

    Integrating Artificial Intelligence with Biomarkers to Meet the Challenges of Dementia

    ✓ Peer-reviewed Digital health tools Journal of dementia and Alzheimer's disease

    Key finding: Dementia, the most common subtype of which is Alzheimer’s disease, represents a significant global and social health challenge.

    Full summary, score breakdown and related studies → Original source

  5. 2025-10-22

    Predicting psychological distress in informal caregivers of older people with dementia: development and interpretation of a nomogram and XGBoost model

    ✓ Peer-reviewed Caregiving BMC Nursing

    Key finding: The final models included six predictors: caregivers' social support, caregivers' employment situation, caregivers' average daily care duration, caregivers' monthly family income, caregivers' self-efficacy and PwD's chronic disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  6. 2025-10-21

    Tau biology, biomarkers, and therapeutics

    ✓ Peer-reviewed Drug development Alzheimer's & dementia (New York, N. Y.)

    Key finding: As Alzheimer's disease (AD) research advances, tau has emerged as both a critical biomarker and a promising therapeutic target, central to understanding disease mechanisms, tracking progression, and guiding treatment development. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2025-10-21

    Speech digital biomarker combined with fluid biomarkers predict cognitive impairment through machine learning

    ✓ Peer-reviewed Cognitive tests and assessment Alzheimer's research & therapy

    Key finding: Significant differences in AD biomarkers were observed among different groups. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2025-10-21

    Neurobiological correlates of Mild Behavioral Impairment: a systematic review and meta-analysis

    ✓ Peer-reviewed Inflammation and the immune system Alzheimer's research & therapy

    Key finding: Across studies, MBI appears to be linked to specific neurobiological markers of AD, including Aβ and tau brain deposition, as well as alterations in the mesolimbic pathway and neurodegenerative and neuroinflammatory fluid biomarker levels. +2 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2025-10-21

    TDP-43 nuclear loss in FTD/ALS causes widespread alternative polyadenylation changes

    ✓ Peer-reviewed Brain tissue and pathology Nature Neuroscience

    Key finding: Here we show that loss of TDP-43 from neuronal nuclei of human brain and disease-causing mutations in TDP-43 are associated with widespread changes in alternative polyadenylation (APA). +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2025-10-21

    TDP-43 loss induces cryptic polyadenylation in ALS/FTD

    ✓ Peer-reviewed Brain tissue and pathology Nature Neuroscience

    Key finding: RNA sequencing (RNA-seq), thiol(SH)-linked alkylation for the metabolic sequencing of RNA (SLAM-seq) and ribosome profiling (Ribo-seq) revealed that distinct cryptic APA categories have different downstream effects on transcript levels and that cryptic 3'UTR extensions can increase RNA stability, leading to increased translation.

    Full summary, score breakdown and related studies → Original source

  11. 2025-10-21

    Implication of dopamine transporter and electroencephalography biomarkers in dementia with lewy bodies

    ✓ Peer-reviewed Lewy body dementia Scientific Reports

    Key finding: In the first step, partial correlation and univariable logistic regression analyses were conducted to screen for EEG or DAT biomarkers significantly associated with clinical characteristics. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2025-10-21

    Using Artificial Intelligence–Based Technologies for the Early Detection of Behavioral and Psychological Symptoms of Dementia: Scoping Review

    ✓ Peer-reviewed Digital health tools JMIR Aging

    Key finding: After screening 3670 articles for eligibility, the review includes 12 studies. +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2025-10-21

    A community-based participatory approach to delivering the Dealing with Dementia program to Black caregivers

    ✓ Peer-reviewed Disparities Frontiers in Public Health

    Key finding: Following the pilot field test, a sustainability plan was co-developed with community facilitators to support continued implementation and ensure that resources spent on DWDAlter were not lost. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2025-10-21

    A scoping review of interventions for Hispanic caregivers of persons living with dementia

    ✓ Peer-reviewed Disparities Alzheimer s & Dementia Behavior & Socioeconomics of Aging

    Key finding: Dementia disproportionately affects Hispanic/Latino caregivers, and while some interventions exist, their consideration of intersectional factors remains unclear.

    Full summary, score breakdown and related studies → Original source

  15. 2025-10-20

    APOE genotype and sex drive microbiome divergence after microbiome standardization in APOE-humanized mice

    ✓ Peer-reviewed Genetics mSphere

    Key finding: Previous studies in humans and humanized APOE mice have demonstrated APOE-genotype-specific differences in the GMB. +2 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2025-10-20

    Real-world lecanemab adoption in Japan 1 year after launch: Insights from 311 specialists on infrastructure and reimbursement barriers

    ✓ Peer-reviewed Health systems and care delivery Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: One fourth reported tight outpatient space and staffing and significantly lower capacity of treatment than anticipated. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2025-10-20

    In Silico Screening and DFT Analysis of Nelumbo nucifera Phytochemicals as Potential BACE-1 Inhibitors for Alzheimer’s disease

    ✓ Peer-reviewed Risk genes beyond APOE Prospects in Pharmaceutical Sciences

    Key finding: Consequently, BACE-1 has become a significant focus for therapeutic interventions in AD. +1 more finding

    Full summary, score breakdown and related studies → Original source

  18. 2025-10-20

    Caregiver Burden and Psychological Distress Among Informal Caregivers for Individuals with Dementia in the Republic of Kazakhstan: A Cross-Sectional Study

    ✓ Peer-reviewed Caregiving Healthcare

    Key finding: Overall, 75.9% of the caregivers reported experiencing at least a mild burden, and the levels of depression, anxiety, and stress among the caregivers were higher than expected. +4 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2025-10-20

    Eye-tracking-based tablet application for enhanced cognitive assessment: a clinical trial for software as a medical device (SaMD)

    ✓ Peer-reviewed Getting a diagnosis GeroScience

    Key finding: Analyses of the full analysis set population revealed a strong positive correlation in total scores between the tests (r = 0.831; 95% CI, 0.743-0.891; p < 0.0001). +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2025-10-20

    Faith-Based Lifestyle Intervention for Diabetes Prevention Among Adults in Bangladesh

    ✓ Peer-reviewed Prevention and risk JAMA Network Open

    Key finding: Of the 799 participants (mean [SD] age, 46.2 [11.6] years; 424 women [53.1%]) randomized, 641 completed the 12-month follow-up and were included in the intention-to-treat analysis: 341 (n = 4 mosques) in the intervention group and 300 (n = 4 mosques) in the control group. +4 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2025-10-20

    Remote, lower-intensity, multidomain lifestyle intervention for subjective cognitive decline or mild cognitive impairment (APPLE-Tree): a multicentre, single-masked, randomised controlled trial

    ✓ Peer-reviewed Prevention and risk The Lancet Healthy Longevity

    Key finding: APPLE-Tree is an accessible intervention associated with small improvements in cognition, although these results were not statistically significant.

    Full summary, score breakdown and related studies → Original source

  22. 2025-10-18

    Barriers and Facilitators for Implementing a Dementia Family Caregiver Support Strategy Among Latinos in Primary Care

    ✓ Peer-reviewed Health systems and care delivery Journal of applied gerontology : the official journal of the Southern Gerontological Society

    Key finding: Latino family caregivers of people with dementia face significant challenges and limited access to support.

    Full summary, score breakdown and related studies → Original source

  23. 2025-10-18

    Research progress on the role of oxidative stress in the pathogenesis of vascular dementia and its treatment

    ✓ Peer-reviewed Lewy body dementia Journal of Stroke and Cerebrovascular Diseases

    Key finding: Oxidative stress is deeply involved in multiple pathological processes of VaD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2025-10-18

    Harmonized Cognitive Assessment Protocol: What makes an HCAP an HCAP? An adaptive architecture for measuring cognitive aging around the world

    ✓ Peer-reviewed Getting a diagnosis The Journals of Gerontology Series B

    Key finding: To balance high-quality measurement of cognitive domains and maintain the ability to perform meaningful cross-national comparisons, each HCAP should include a common set of at least three to four continuously distributed test items per domain that can link domains across studies. +4 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2025-10-17

    Advances of therapeutic strategies for Alzheimer's disease

    ✓ Peer-reviewed Treatments Journal of neurology

    Key finding: The past several decades have yielded deeper insights into the multifactorial pathogenesis and intervention strategies of Alzheimer's disease (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →