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Alzheimer's biomarkers in daily practice (ABIDE) project: Rationale and design
Arno de Wilde, Ingrid S van Maurik, Marleen Kunneman, Femke Bouwman, Marissa Zwan, Eline A J Willemse, Geert Jan Biessels, Mirella Minkman et al.. Alzheimer's & dementia (Amsterdam, Netherlands), 2017-01-23
Topic: Plasma and spinal-fluid biomarkers
Based on retrospective data, we develop personalized risk estimates for MCI patients. Prospectively, we collect MRI and CSF data from 200 patients from local memory clinics and amyloid PET from 500 patients in a tertiary setting, to optimize application of these tests in daily practice. Furthermore, ABIDE will develop strategies for optimal patient-clinician conversations. Ultimately, this will result in a set of practical tools for clinicians to support the choice of diagnostic tests and facilitate the interpretation and communication of their results.
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APA 7th
de Wilde, A., van Maurik, I. S., Kunneman, M., Bouwman, F., Zwan, M., Willemse, E. A. J., et al. (2017). Alzheimer's biomarkers in daily practice (ABIDE) project: Rationale and design. Alzheimer's & dementia (Amsterdam, Netherlands). https://doi.org/10.1016/j.dadm.2017.01.003
Vancouver
de Wilde A, van Maurik IS, Kunneman M, Bouwman F, Zwan M, Willemse EAJ, et al. Alzheimer's biomarkers in daily practice (ABIDE) project: Rationale and design. Alzheimer's & dementia (Amsterdam, Netherlands). 2017. doi:10.1016/j.dadm.2017.01.003. PMID: 28239639.
BibTeX
@article{dewilde2017-28239639,
author = {de Wilde, Arno and van Maurik, Ingrid S and Kunneman, Marleen and Bouwman, Femke and Zwan, Marissa and Willemse, Eline A J and Biessels, Geert Jan and Minkman, Mirella and others},
title = {{Alzheimer's biomarkers in daily practice (ABIDE) project: Rationale and design}},
journal = {Alzheimer's \& dementia (Amsterdam, Netherlands)},
year = {2017},
doi = {10.1016/j.dadm.2017.01.003},
pmid = {28239639},
url = {https://doi.org/10.1016/j.dadm.2017.01.003}
}
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Key findings
- Based on retrospective data, we develop personalized risk estimates for MCI patients.
- Prospectively, we collect MRI and CSF data from 200 patients from local memory clinics and amyloid PET from 500 patients in a tertiary setting, to optimize application of these tests in daily practice.
- Furthermore, ABIDE will develop strategies for optimal patient-clinician conversations.
- Ultimately, this will result in a set of practical tools for clinicians to support the choice of diagnostic tests and facilitate the interpretation and communication of their results.
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Study details
- Participants200
- Evidence strengthLow
How this study scored 52/100
Published in a leading specialty journal. Scored zero for study design, effect reported and randomised / blinded because the record does not state it. We have no data on journal's citation record, times cited, citations per year, impact for its field and year, cited by studies here, still being cited, senior author's track record, institution's track record, multi-centre collaboration and free to read, so those were left out: it earned 29 of the 56 points we could judge it on, which is 52 out of 100.
| Component | Points | Why |
|---|---|---|
| Journal tier | 9 / 10 | Tier 2 — leading specialty journal (Alzheimer's & dementia (Amsterdam, Netherlands)) |
| Journal's citation record | — / 4 | No journal record from OpenAlex — left out of this score |
| Study design | 0 / 12 | No study design recorded — scores zero, not guessed (not stated in the record — scored 0) |
| Strength of evidence | 1 / 5 | Rated “low” in our summary |
| Peer-review validation | 10 / 10 | Peer-reviewed. Published as an article in a named peer-reviewed journal. |
| How recent | 2 / 5 | 2017 — within 10 year(s) of the newest study here |
| Sample size | 2 / 4 | 200 participants |
| Effect reported | 0 / 3 | No effect size reported — scores zero (not stated in the record — scored 0) |
| Studied in people | 3 / 3 | Studied in people (participant count stated) |
| Randomised / blinded | 0 / 2 | No randomisation or blinding stated — scores zero (not stated in the record — scored 0) |
| Times cited | — / 7 | No citation count (not found in OpenAlex) — left out of this score |
| Citations per year | — / 5 | No citation count or no year — left out of this score |
| Impact for its field and year | — / 6 | No field-weighted citation impact (OpenAlex has none yet) — left out of this score |
| Cited by studies here | — / 6 | Not yet checked against this library's citation graph — left out of this score |
| Still being cited | — / 4 | No yearly citation counts — left out of this score |
| Senior author's track record | — / 4 | Senior author's record not available — left out of this score |
| Institution's track record | — / 3 | No institution listed in OpenAlex — left out of this score |
| Multi-centre collaboration | — / 3 | Institutions not listed — left out of this score |
| Indexed in PubMed | 2 / 2 | Indexed in PubMed (PMID 28239639) |
| Free to read | — / 2 | Access not recorded — left out of this score |
| Points | 29 / 56 | Scored on 10 of 20 parts. We have no data for the rest, so they are left out: 29 of the 56 points we could judge it on is 52 out of 100. |
| Total | 52 / 100 | — |
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