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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 14,201–14,225 of 27,380 studies, newest first · page 569 of 1096.

March 2018 22

  1. 2018-03-02

    Differential Phagocytic Properties of CD45low Microglia and CD45high Brain Mononuclear Phagocytes-Activation and Age-Related Effects

    ✓ Peer-reviewed TREM2 and immune genetics Frontiers in immunology

    Key finding: While CD11b + CD45 low microglia account for the majority of CNS MPs, a small population of CD11b + CD45 high CNS MPs is also recognized in AD that surround Aβ plaques. +3 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2018-03-01

    TDP-43 Prions

    ✓ Peer-reviewed Brain tissue and pathology Cold Spring Harbor perspectives in medicine

    Key finding: Recent studies have shown that, like tau and α-synuclein, TAR-DNA binding protein of 43 kDa (TDP-43) can form aggregates in vitro in a seed-dependent, self-templating, prion-like manner.

    Full summary, score breakdown and related studies → Original source

  3. 2018-03 month only

    Mediterranean Diet in Preventing Neurodegenerative Diseases

    ✓ Peer-reviewed Prevention and risk Current nutrition reports

    Key finding: We reviewed the most recent literature examining the associations between the Mediterranean-style diet (MD), neurodegenerative diseases, and markers and mechanisms of neurodegeneration.

    Full summary, score breakdown and related studies → Original source

  4. 2018-03 month only

    Color Vision Impairment Differentiates Alzheimer Dementia From Dementia With Lewy Bodies

    ✓ Peer-reviewed Risk factors Journal of geriatric psychiatry and neurology

    Key finding: Fifty-two patients were included in this study with a median age of 77 years, of which 44% were female. +4 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2018-03-01

    Microglia-Mediated Synapse Loss in Alzheimer's Disease

    ✓ Peer-reviewed Risk factors The Journal of neuroscience : the official journal of the Society for Neuroscience

    Key finding: However, several recent studies have demonstrated a direct role of microglia in "neuro" degeneration observed in AD by promoting phagocytosis of neuronal, in particular, synaptic structures. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2018-03-01

    Extracellular Monomeric and Aggregated Tau Efficiently Enter Human Neurons through Overlapping but Distinct Pathways

    ✓ Peer-reviewed Drug development Cell reports

    Key finding: These data suggest that tau entry to human neurons is a physiological process and not a disease-specific phenomenon.

    Full summary, score breakdown and related studies → Original source

  7. 2018-03-01

    Fibre-specific white matter reductions in Alzheimer's disease and mild cognitive impairment

    ✓ Peer-reviewed Brain scans and imaging Brain : a journal of neurology

    Key finding: Alzheimer's disease is increasingly considered a large-scale network disconnection syndrome, associated with progressive aggregation of pathological proteins, cortical atrophy, and functional disconnections between brain regions. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2018-03-01

    Treatment of autonomic dysfunction in Parkinson disease and other synucleinopathies

    ✓ Peer-reviewed Clinical safety Movement disorders : official journal of the Movement Disorder Society

    Key finding: For example, gastrointestinal dysfunction can lead to impaired drug pharmacodynamics causing a worsening in motor symptoms, and neurogenic orthostatic hypotension can cause syncope, falls, and fractures. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2018-03-01

    Detection of Alzheimer Disease (AD)-Specific Tau Pathology in AD and NonAD Tauopathies by Immunohistochemistry With Novel Conformation-Selective Tau Antibodies

    ✓ Peer-reviewed Disease mechanisms Journal of neuropathology and experimental neurology

    Key finding: In cases with co-occurring AD tauopathy, GT-7 and GT-38 distinguish comorbid AD tau from pathological tau in frontotemporal lobar degeneration characterized by tau inclusions (FTLD-Tau), as confirmed by the presence of both 3 versus 4 microtubule-binding repeat isoforms (3R and 4R tau isoforms, respectively), in AD neurofibrillary tangles but not in the tau aggregates of CBD, PSP, or PiD. +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2018-03-01

    2018 Alzheimer's disease facts and figures

    ✓ Peer-reviewed How common it is Alzheimer s & Dementia

    Between 2000 and 2015, deaths resulting from stroke, heart disease, and prostate cancer decreased, whereas deaths from AD increased 123%.

    Full summary, score breakdown and related studies → Original source

  11. 2018-03-01

    Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer's Disease Models

    ✓ Peer-reviewed TREM2 and immune genetics Neuron

    Key finding: To study whether increasing TREM2 gene dosage could modify the disease pathogenesis, we developed BAC transgenic mice expressing human TREM2 (BAC-TREM2) in microglia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2018-03-01

    TREM2 Is a Receptor for β-Amyloid that Mediates Microglial Function

    ✓ Peer-reviewed TREM2 and immune genetics Neuron

    Key finding: Neurobiological functions of TREM2 and its pathophysiological ligands remain elusive. +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2018-03-01

    CSF biomarkers of Alzheimer's disease concord with amyloid-β PET and predict clinical progression: A study of fully automated immunoassays in BioFINDER and ADNI cohorts

    ✓ Peer-reviewed Mild cognitive impairment Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Elecsys CSF biomarker assays may provide reliable alternatives to PET in Alzheimer's disease diagnosis. +2 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2018-03-01

    Early striatal amyloid deposition distinguishes Down syndrome and autosomal dominant Alzheimer's disease from late-onset amyloid deposition

    ✓ Peer-reviewed Down syndrome and Alzheimer's Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Disorders associated with early-life alterations in amyloid precursor protein production or processing are associated with a distinct pattern of early striatal fibrillary Aβ deposition before significant cognitive impairment. +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2018-03-01

    Vascular smooth muscle contraction in hypertension

    ✓ Peer-reviewed Risk factors Cardiovascular research

    Key finding: Growing evidence indicates that contraction is also regulated by calcium-independent mechanisms involving RhoA-Rho kinase, protein Kinase C and mitogen-activated protein kinase signalling, reactive oxygen species, and reorganization of the actin cytoskeleton.

    Full summary, score breakdown and related studies → Original source

  16. 2018-03-01

    Omega-3 Polyunsaturated Fatty Acids and Their Health Benefits

    ✓ Peer-reviewed Risk factors Annual review of food science and technology

    Key finding: Omega-3 polyunsaturated fatty acids (PUFAs) include α-linolenic acid (ALA; 18:3 ω-3), stearidonic acid (SDA; 18:4 ω-3), eicosapentaenoic acid (EPA; 20:5 ω-3), docosapentaenoic acid (DPA; 22:5 ω-3), and docosahexaenoic acid (DHA; 22:6 ω-3). +3 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2018-03-01

    Changes in Everyday and Digital Health Technology Use Among Seniors in Declining Health

    ✓ Peer-reviewed Digital health tools The journals of gerontology. Series A, Biological sciences and medical sciences

    Key finding: Between 2011 and 2014, seniors experiencing health decline used various digital health technologies at low absolute rates (range: 1%-20%). +1 more finding

    Full summary, score breakdown and related studies → Original source

  18. 2018-03-01

    Clinical phenotypes of delirium during critical illness and severity of subsequent long-term cognitive impairment: a prospective cohort study

    ✓ Peer-reviewed How common it is The Lancet. Respiratory medicine

    Key finding: Our findings suggest that clinicians should consider sedative-associated, hypoxic, and septic delirium, which often co-occur, as distinct indicators of acute brain injury and seek to identify all potential risk factors that may impact on long-term cognitive impairment, especially those that are iatrogenic and potentially modifiable such as sedation. +1 more finding

    Full summary, score breakdown and related studies → Original source

  19. 2018-03-01

    Reminiscence therapy for dementia

    ✓ Peer-reviewed Caregiving The Cochrane database of systematic reviews

    Key finding: We undertook subgroup analysis by setting (community versus care home) and by modality (individual versus group). +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2018-03-01

    Effect of the Mediterranean diet on cognition and brain morphology and function: a systematic review of randomized controlled trials

    ✓ Peer-reviewed Prevention and risk The American journal of clinical nutrition

    Key finding: Five RCTs of the Mediterranean diet and cognition have been published to date. +4 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2018-03-01

    Associations of the Top 20 Alzheimer Disease Risk Variants With Brain Amyloidosis

    ✓ Peer-reviewed Genetics JAMA neurology

    Key finding: The precise mechanism through which many of these genes are associated with AD remains unknown. +2 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2018-03-01

    Rates of Amyloid Imaging Positivity in Patients With Primary Progressive Aphasia

    ✓ Peer-reviewed Biomarkers JAMA neurology

    Key finding: Inclusion criteria included clinical diagnosis of PPA; availability of complete speech, language, and cognitive testing; magnetic resonance imaging performed within 6 months of the cognitive evaluation; and PET carbon 11-labeled Pittsburgh Compound-B or florbetapir F 18 brain scan results. +4 more findings

    Full summary, score breakdown and related studies → Original source

February 2018 3

  1. 2018-02-28

    SLAB51 Probiotic Formulation Activates SIRT1 Pathway Promoting Antioxidant and Neuroprotective Effects in an AD Mouse Model

    ✓ Peer-reviewed Disease mechanisms Molecular neurobiology

    Key finding: In this study, we explored the properties of a probiotic formulation (namely SLAB51) in counteracting brain oxidative damages associated with Alzheimer's disease (AD). +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2018-02-28

    Current Clinical Applications of Diffusion-Tensor Imaging in Neurological Disorders

    ✓ Peer-reviewed Vascular contributions Journal of clinical neurology (Seoul, Korea)

    Key finding: The signal contrast in DTI is generated by differences in the Brownian motion of the water molecules in brain tissue. +4 more findings

    Full summary, score breakdown and related studies → Original source

  3. 2018-02-28

    A key role for MAM in mediating mitochondrial dysfunction in Alzheimer disease

    ✓ Peer-reviewed Risk genes beyond APOE Cell death & disease

    Key finding: A major reason for this is the central role that this subdomain of the ER plays in metabolic regulation and in mitochondrial biology. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →