Get help now — free helplines

You can call any of these for free. You do not need a diagnosis, an appointment, or a crisis to call — questions and plain exhaustion are reasons enough.

  • Alzheimer's Association 24/7 Helpline 800-272-3900 24 hours a day, 365 days a year Free, confidential support and information for people with dementia, caregivers, families and the public. Master's-level clinicians. Also Spanish.
  • 988 Suicide & Crisis Lifeline 988 24/7 Call or text 988, or chat at 988lifeline.org. For anyone in emotional distress or a mental-health crisis, including caregivers.
  • Alzheimer's Foundation of America (AFA) Helpline 866-232-8484 9:00 am - 9:00 pm ET, seven days a week Licensed social workers providing support, info and referrals. Also text message and web chat. Text: 646-586-5283

In a medical emergency, call 911. More numbers, and what each line does, on the help page.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 14,476–14,500 of 27,380 studies, newest first · page 580 of 1096.

December 2017 25

  1. 2017-12-29

    Cerebrovascular and amyloid pathology in predementia stages: the relationship with neurodegeneration and cognitive decline

    ✓ Peer-reviewed Tau biomarkers Alzheimer's research & therapy

    Key finding: Cerebrovascular disease (CVD) and amyloid-β (Aβ) often coexist, but their influence on neurodegeneration and cognition in predementia stages remains unclear. +3 more findings

  2. 2017-12-28

    Botanicals and phytochemicals active on cognitive decline: The clinical evidence

    ✓ Peer-reviewed Prevention trials Pharmacological research

    Key finding: Then, the aim of the present study was to review and comment the available evidence on botanicals and phytochemicals with a clinically demonstrable effect on cognitive decline. +4 more findings

  3. 2017-12-28

    Test-Retest Reproducibility for the Tau PET Imaging Agent Flortaucipir F 18

    ✓ Peer-reviewed Brain scans and imaging Journal of nuclear medicine : official publication, Society of Nuclear Medicine

    Key finding: Test-retest analyses demonstrated low variability in flortaucipir F 18 SUVR. +3 more findings

  4. 2017-12-27

    Underreporting of Gender and Race/Ethnicity Differences in NIH-Funded Dementia Caregiver Support Interventions

    ✓ Peer-reviewed Caregiving American journal of Alzheimer's disease and other dementias

    Key finding: The majority of studies included women and racial/ethnic minorities; however, 67% did not report results by gender or racial/ethnic group. +1 more finding

  5. 2017-12-27
  6. 2017-12-27

    A Novel Screening Method to Identify Late-Stage Dementia Patients for Palliative Care Research and Practice

    ✓ Peer-reviewed End-of-life care Journal of pain and symptom management

    Key finding: A novel method using an EHR phenotype plus brief medical record review is effective to identify hospitalized patients with late-stage dementia.

  7. 2017-12-27

    Physical exercise improves strength, balance, mobility, and endurance in people with cognitive impairment and dementia: a systematic review

    ✓ Peer-reviewed Clinical safety Journal of physiotherapy

    Key finding: Question Does physical exercise training improve physical function and quality of life in people with cognitive impairment and dementia? +3 more findings

  8. 2017-12-27

    Adherence to Mediterranean Diet and Frailty

    ✓ Peer-reviewed Prevention trials Journal of the American Medical Directors Association

    Key finding: According to study results, a higher adherence to the Mediterranean diet was associated with lower odds of frailty, irrespective of the definition used. +2 more findings

  9. 2017-12-27

    The Efficacy of Cognitive Intervention in Mild Cognitive Impairment (MCI): a Meta-Analysis of Outcomes on Neuropsychological Measures

    ✓ Peer-reviewed Prevention trials Neuropsychology review

    Key finding: As such, this meta-analytic review was conducted to examine the efficacy of cognitive intervention in individuals diagnosed with mild cognitive impairment (MCI) versus MCI controls based on performance of neuropsychological outcome measures in randomized controlled trials (RCT). +3 more findings

  10. 2017-12-27
  11. 2017-12-27
  12. 2017-12-27

    CSF neurofilament light chain and phosphorylated tau 181 predict disease progression in PSP

    ✓ Peer-reviewed Biomarkers Neurology

    Key finding: Both CSF p-tau and NfL correlate with disease severity and rate of disease progression in PSP. +3 more findings

  13. 2017-12-26

    The tau positron-emission tomography tracer AV-1451 binds with similar affinities to tau fibrils and monoamine oxidases

    ✓ Peer-reviewed Brain scans and imaging Movement disorders : official journal of the Movement Disorder Society

    Key finding: High affinity of AV-1451 for monoamine oxidase proteins may limit its utility as a tau PET tracer in PSP and Alzheimer's disease because of high levels of monoamine oxidase expression in brain regions also affected by tau deposition, especially if monoamine oxidase levels change over time or with a treatment intervention. © 2017 International Parkinson and Movement Disorder Society. +2 more findings

  14. 2017-12-24

    Efficacy of computer-based cognitive training in neuropsychological performance of patients with multiple sclerosis: A systematic review and meta-analysis

    ✓ Peer-reviewed Prevention trials Multiple sclerosis and related disorders

    Key finding: The present meta-analysis revealed a significant effect for computer-based cognitive training on the performance of the memory domain of patients with MS. This finding may have significant implications in the current treatment practice when cognitive decline is detected in MS patients. +4 more findings

  15. 2017-12-22

    Neuroinflammatory responses in Alzheimer's disease

    ✓ Peer-reviewed Inflammation and the immune system Journal of neural transmission (Vienna, Austria : 1996)

    Key finding: They involve various cellular and molecular players and associate interaction between the central nervous system (CNS) and the periphery. +4 more findings

  16. 2017-12-21

    The role of microbial amyloid in neurodegeneration

    ✓ Peer-reviewed Inflammation and the immune system PLoS pathogens

    Key finding: Recent work has demonstrated that the microbiota also influences brain function in healthy and diseased individuals. +3 more findings

  17. 2017-12-20

    Tau-mediated Neurodegeneration and Potential Implications in Diagnosis and Treatment of Alzheimer's Disease

    ✓ Peer-reviewed Drug development Chinese medical journal

    Key finding: Amyloid plaques enriched with extracellular amyloid beta (Aβ) and intracellular neurofibrillary tangles comprised of hyperphosphorylated tau proteins are the two main pathological hallmarks of AD. +4 more findings

  18. 2017-12-20

    Analyzing the relationship between store attributes, satisfaction, patronage-intention and lifestyle in food and grocery store choice behavior

    ✓ Peer-reviewed Risk factors International Journal of Retail & Distribution Management

    Key finding: Practical implications With 100 percent foreign direct investment permitted in the F&G category in India, the research outcomes will be useful to all food retailers (prospective and current) interested in this retail market. +4 more findings

  19. 2017-12-20

    Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages

    ✓ Peer-reviewed Tau biomarkers Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: In CN subjects, study-wide significant (P -9 ) loci were identified for total tau near SRRM4 and C14orf79 and for hippocampal volume near MTUS1. +3 more findings

  20. 2017-12-19

    Exenatide exerts cognitive effects by modulating the BDNF-TrkB neurotrophic axis in adult mice

    ✓ Peer-reviewed Drug development Neurobiology of aging

    Key finding: Moreover, recent evidence indicates that GLP-1 modulates the activity of the brain-derived neurotrophic factor (BDNF). +1 more finding

  21. 2017-12-19

    Predictors of Smartphone Uses for Health Information Seeking in the Korean Elderly

    ✓ Peer-reviewed Cognitive tests and assessment Social work in public health

    Key finding: SHIS was significantly predicted by younger age, higher education levels, having a regular exercise, higher medical expenditures, and health literacy.

  22. 2017-12-19

    Distinct differences in prion-like seeding and aggregation between Tau protein variants provide mechanistic insights into tauopathies

    ✓ Peer-reviewed Disease mechanisms The Journal of biological chemistry

    Key finding: Our findings revealed stark differences between FTDP-17 Tau variants in their ability to be seeded, with variants at Pro 301 and Ser 320 showing robust aggregation with seeding. +2 more findings

  23. 2017-12-19

    Involvement of Astrocytes in Alzheimer's Disease from a Neuroinflammatory and Oxidative Stress Perspective

    ✓ Peer-reviewed Inflammation and the immune system Frontiers in molecular neuroscience

    Key finding: Although many explicative theories have been proposed, precise pathophysiological mechanisms are unknown. +3 more findings

  24. 2017-12-19

    The pathology and pathophysiology of vascular dementia

    ✓ Peer-reviewed Brain tissue and pathology Neuropharmacology

    Key finding: Consensus and accurate diagnosis of clinically suspected VaD relies on wide-ranging clinical, neuropsychological and neuroimaging measures in life but more importantly pathological confirmation. +3 more findings

  25. 2017-12-19

Browse the library by subject, with the full score breakdown →