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What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 26,951–26,975 of 27,380 studies, newest first · page 1079 of 1096.

May 1991 2

  1. 1991-05-01

    Hydrated autoclave pretreatment enhances tau immunoreactivity in formalin-fixed normal and Alzheimer's disease brain tissues

    ✓ Peer-reviewed Drug development Laboratory investigation; a journal of technical methods and pathology

    Key finding: In previous studies on normal tau distribution, different optimized fixations that effectively preserve tau antigenicity were used but none of these revealed all of these compartments together. +1 more finding

  2. 1991-05-01

April 1991 7

  1. 1991-04-01

    A review of chemical issues in 1H NMR spectroscopy: N-acetyl-L-aspartate, creatine and choline

    ✓ Peer-reviewed Vascular contributions NMR in biomedicine

    Key finding: NAA is elevated in several degenerative neurological conditions including amyotrophic lateral sclerosis and canavan disease, and in high concentrations it may behave like a neurotoxin. +4 more findings

  2. 1991-04-01
  3. 1991-04-01

    The Consortium to Establish a Registry for Alzheimer's Disease (CERAD)

    ✓ Peer-reviewed Cognitive tests and assessment Neurology

    Key finding: The Neuropathology Task Force of the Consortium to Establish a Registry for Alzheimer's Disease (CERAD) has developed a practical and standardized neuropathology protocol for the postmortem assessment of dementia and control subjects. +4 more findings

  4. 1991-04-01

    How old are the elderly?

    ✓ Peer-reviewed Health systems and care delivery The British Journal of Psychiatry

    Key finding: Contrary to the experience at the Crichton Royal, our major difficulty is providing in-patient beds for the functionally ill, which again may be a local problem.

  5. 1991-04-01

    Characteristics of age-related language decline in adults with Down syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's Mental retardation

    Key finding: Our results showed significant relations between aging and language comprehension and aging and self-help skills. +1 more finding

  6. 1991-04-01

    Ubiquitin-immunoreactive intraneuronal inclusions in amyotrophic lateral sclerosis. Morphology, distribution, and specificity

    ✓ Peer-reviewed Disparities Brain : a journal of neurology

    Key finding: We conclude that the presence of ubiquitin-IR inclusions in lower motor neurons represents a characteristic pathological feature of ALS in its various clinical forms.

  7. 1991-04-01

    Very mild Alzheimer's disease: informant-based clinical, psychometric, and pathologic distinction from normal aging

    ✓ Peer-reviewed Getting a diagnosis Neurology

    Key finding: These findings indicate that even "questionable" dementia can be diagnostic for Alzheimer's disease.

March 1991 7

  1. 1991-03-01

    Advances in Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms The FASEB Journal

    Key finding: But in the past several years there have been significant extensions of our knowledge of the disease and advances in determining the molecular changes underlying the disorder.

  2. 1991-03-01

    Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions

    ✓ Peer-reviewed Inflammation and the immune system Journal of Clinical Investigation

    Key finding: LT was associated with CD3+ lymphocytes and Leu-M5+ microglia cells at the lesion edge and to a lesser extent, in adjacent white matter. +2 more findings

  3. 1991-03-01

    Advance directives for medical care--a case for greater use

    ✓ Peer-reviewed Getting a diagnosis The New England journal of medicine

    Key finding: When people are asked to imagine themselves incompetent with a poor prognosis, they decide against life-sustaining treatments about 70 percent of the time.

  4. 1991-03-01

    Detection of abnormal memory decline in mild cases of Alzheimer's disease using CERAD neuropsychological measures

    ✓ Peer-reviewed Risk factors Archives of neurology

    Key finding: The test for delayed recall was found to be the best overall discriminatory measure. +2 more findings

  5. 1991-03-01

    Visual impairment and cognitive dysfunction in Alzheimer's disease

    ✓ Peer-reviewed Risk factors Journal of general internal medicine

    Key finding: Visual impairment is associated with both an increased risk and an increased clinical severity of Alzheimer's disease, but the increased risk may not be consistent with a progressive dose-response relationship. +4 more findings

  6. 1991-03-01

    Ultrastructural localization of beta-amyloid, tau, and ubiquitin epitopes in extracellular neurofibrillary tangles

    ✓ Peer-reviewed Drug development Proceedings of the National Academy of Sciences of the United States of America

    Key finding: The antigenic changes in E-NFTs suggest that when NFTs become extracellular they lose the N and, possibly, the C termini of tau while maintaining the intermediate region of the molecule; they also lose the N-terminal two-thirds of Ub while the C-terminal conjugation site of Ub is preserved. +1 more finding

  7. 1991-03-01

    Expression of the amyloid precursor protein gene in mouse oocytes and embryos

    ✓ Peer-reviewed Down syndrome and Alzheimer's Proceedings of the National Academy of Sciences of the United States of America

    Key finding: Screens for APP clones in embryonic cDNA libraries from the egg cylinder stage and the early somite stage were used to confirm the results of the polymerase chain reaction, and APP clone abundance was found to increase 10-fold between the two stages.

February 1991 9

  1. 1991-02-21

    Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease

    ✓ Peer-reviewed Genetics Nature

    Key finding: In this kindred, which shows linkage to chromosome 21 markers, there is a point mutation in the APP gene. +2 more findings

  2. 1991-02-01

    Marked cerebrospinal fluid void: indicator of successful shunt in patients with suspected normal-pressure hydrocephalus

    ✓ Peer-reviewed Digital health tools Radiology

    Key finding: A significant (P less than .003) correlation existed between good or excellent response to surgery and an increased CSF flow void. +1 more finding

  3. 1991-02-01

    The screen for caregiver burden

    ✓ Peer-reviewed Caregiving The Gerontologist

    Key finding: Finally, evidence suggests that changes in OB and SB over time are explained by changes in care-recipient functioning and caregiver distress.

  4. 1991-02-01

    Antibodies to non-beta regions of the beta-amyloid precursor protein detect a subset of senile plaques

    ✓ Peer-reviewed Drug development The American journal of pathology

    Key finding: Here the presence and distribution within senile plaques of various epitopes of the beta-amyloid precursor protein (APP) are compared with the distribution of A beta P itself and markers for plaque neurites. +2 more findings

  5. 1991-02-01

    Quinolinic acid in cerebrospinal fluid and serum in HIV-1 infection: relationship to clinical and neurological status

    ✓ Peer-reviewed Tau biomarkers Annals of neurology

    Key finding: CSF concentrations of quinolinic acid were significantly correlated to the severity of the neuropsychological deficits. +1 more finding

  6. 1991-02-01

    The cardiovascular health study: Design and rationale

    ✓ Peer-reviewed Long-term cohort studies Annals of Epidemiology

    Key finding: The Cardiovascular Health Study (CHS) is a population-based, longitudinal study of coronary heart disease and stroke in adults aged 65 years and older. +3 more findings

  7. 1991-02-01
  8. 1991-02-01

    The promoter activity of the gene encoding Alzheimer beta-amyloid precursor protein (APP) is regulated by two blocks of upstream sequences

    ✓ Peer-reviewed Down syndrome and Alzheimer's Brain research. Molecular brain research

    Key finding: Transfection of these constructs into Hela and PC12 cells revealed the presence of two blocks of regulatory sequences in the APP promoter. +3 more findings

  9. 1991-02-01

    Mini-Mental State exam scores vary with education in blacks and whites

    ✓ Peer-reviewed Disparities Journal of the American Geriatrics Society

    Key finding: Previous studies have suggested that education and race may affect performance on standardized mental status tests. +2 more findings

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