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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 15,701–15,725 of 27,380 studies, newest first · page 629 of 1096.

October 2016 25

  1. 2016-10-20

    Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans

    ✓ Peer-reviewed Genetics Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: Two SNPs at novel loci, rs112404845 (P = 3.8 × 10-8), upstream of COBL, and rs16961023 (P = 4.6 × 10-8), downstream of SLC10A2, obtained genome-wide significant evidence of association with the posterior liability. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2016-10-20

    Classification of CT brain images based on deep learning networks

    ✓ Peer-reviewed Digital health tools Computer methods and programs in biomedicine

    Key finding: As a result, the classification accuracy rates rendered by this elaborated CNN architecture are 85.2%, 80% and 95.3% for classes of AD, lesion and normal respectively with an average of 87.6%. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2016-10-20

    Association Between Life's Simple 7 and Noncardiovascular Disease: The Multi-Ethnic Study of Atherosclerosis

    ✓ Peer-reviewed Prevention and risk Journal of the American Heart Association

    Key finding: The American Heart Association's LS7 score identified individuals who were vulnerable to multiple chronic nonvascular conditions. +3 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2016-10-20

    Plasma levels of apolipoprotein E, APOE genotype and risk of dementia and ischemic heart disease: A review

    ✓ Peer-reviewed Genetics Atherosclerosis

    Key finding: Approximately half of plasma apoE is associated with triglyceride-rich lipoproteins, where apoE serves as the main ligand for the low density lipoprotein (LDL) receptor and the LDL receptor Related Protein (LRP). +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2016-10-19

    Increasing comorbidity and health services utilization in older adults with prior stroke

    ✓ Peer-reviewed Digital health tools Neurology

    Key finding: Our findings demonstrate the importance of community-based patient-centered care strategies for stroke survivors that address their range of health needs and prevent more costly acute care use. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2016-10-19

    High fat diet induces brain insulin resistance and cognitive impairment in mice

    ✓ Peer-reviewed Prevention trials Biochimica et biophysica acta. Molecular basis of disease

    Key finding: High fat diet-induced obesity is associated with insulin resistance (IR) and other chronic, diet related illnesses, including dementia. +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2016-10-18

    Emerging Putative Associations between Non-Coding RNAs and Protein-Coding Genes in Neuropathic Pain: Added Value from Reusing Microarray Data

    ✓ Peer-reviewed Down syndrome and Alzheimer's Frontiers in neurology

    Key finding: Relevance was therefore assigned to differential expression of neighbor protein-coding genes, with neighborhood defined by a fixed genomic distance from long or antisense ncRNA loci, and of parental genes associated with pseudogenes. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2016-10-18

    The economic burden of dementia in China, 1990-2030: implications for health policy

    ✓ Peer-reviewed Caregiving Bulletin of the World Health Organization

    Key finding: The estimated total annual costs of dementia in China increased from 0.9 billion United States dollars (US$) in 1990 to US$ 47.2 billion in 2010 and were predicted to reach US$ 69.0 billion in 2020 and US$ 114.2 billion in 2030. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2016-10-18

    Inhomogeneous distribution of Alzheimer pathology along the isocortical relief. Are cortical convolutions an Achilles heel of evolution?

    ✓ Peer-reviewed Biomarkers Brain pathology (Zurich, Switzerland)

    Key finding: It was shown that both plaques and tangles were more prominent in sulcal fundi than gyri crowns. +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2016-10-17

    The role of optical coherence tomography in Alzheimer's disease

    ✓ Peer-reviewed Brain scans and imaging International journal of retina and vitreous

    Key finding: The purpose of this article is to review the main findings on OCT in AD patients, to discuss the role of this important diagnostic tool in these patients and how OCT technology may be useful in understanding morphological retinal changes in AD.

    Full summary, score breakdown and related studies → Original source

  11. 2016-10-17

    Mutations, associated with early-onset Alzheimer's disease, discovered in Asian countries

    ✓ Peer-reviewed Risk genes beyond APOE Clinical interventions in aging

    Key finding: However, recent studies have been started to investigate the genes and mutations associated with AD in Korea, the People's Republic of China, and Malaysia. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2016-10-17

    Oxidative Stress and the Central Nervous System

    ✓ Peer-reviewed Risk factors The Journal of pharmacology and experimental therapeutics

    Key finding: Oxidative stress occurs upon excessive free radical production resulting from an insufficiency of the counteracting antioxidant response system. +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2016-10-17

    Colocalization of cerebral iron with Amyloid beta in Mild Cognitive Impairment

    ✓ Peer-reviewed Mild cognitive impairment Scientific reports

    Key finding: Quantitative Susceptibility Mapping (QSM) MRI at 7 Tesla and 11-Carbon Pittsburgh-Compound-B PET were used for investigating the relationship between brain iron and Amyloid beta (Aβ) plaque-load in a context of increased risk for Alzheimer's disease (AD), as reflected by the Apolipoprotein E ε4 (APOE-e4) allele and mild cognitive impairment (MCI) in elderly subjects. +3 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2016-10-17

    VNTR-DAT1 and COMTVal158Met Genotypes Modulate Mental Flexibility and Adaptive Behavior Skills in Down Syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's Frontiers in behavioral neuroscience

    Key finding: Our results suggest that genetic variants of COMTVal158Met and VNTR-DAT1 may contribute to PFC-dependent cognition, while only COMTVal158Met is involved in behavioral phenotypes of DS, similar to euploid population.

    Full summary, score breakdown and related studies → Original source

  15. 2016-10-15

    Proteostasis regulation by the ubiquitin system

    ✓ Peer-reviewed Disease mechanisms Essays in biochemistry

    Key finding: Disturbances to protein homoeostasis (proteostasis) can result in severe cellular phenotypes and are closely linked with the accumulation of microscopically visible deposits of aggregated proteins.

    Full summary, score breakdown and related studies → Original source

  16. 2016-10-15

    Neuronal exosomes reveal Alzheimer's disease biomarkers in Down syndrome

    ✓ Peer-reviewed Down syndrome and Alzheimer's Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: These early increases in Aβ 1-42 , P-T181-tau, and P-S396-tau in individuals with DS may provide a basis for early intervention as targeted treatments become available. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2016-10-15

    Review of Safety and Efficacy of Sleep Medicines in Older Adults

    ✓ Peer-reviewed Risk factors Clinical therapeutics

    Key finding: Although non-BzRAs have improved safety profiles compared with benzodiazepines, their side effects include dementia, serious injury, and fractures, which should limit their use. +2 more findings

    Full summary, score breakdown and related studies → Original source

  18. 2016-10-13

    Targeting SUMO-1ylation Contrasts Synaptic Dysfunction in a Mouse Model of Alzheimer's Disease

    ✓ Peer-reviewed Disease mechanisms Molecular neurobiology

    Key finding: Our previous findings have shown that increased SUMOylation at presynaptic level reduces the KCl-induced glutamate release. +1 more finding

    Full summary, score breakdown and related studies → Original source

  19. 2016-10-12

    Intersectin scaffold proteins and their role in cell signaling and endocytosis

    ✓ Peer-reviewed Prevention trials Biochimica et biophysica acta. Molecular cell research

    Key finding: ITSNs participate in several human cancers, such as neuroblastomas and glioblastomas, while their downregulation is associated with lung injury.

    Full summary, score breakdown and related studies → Original source

  20. 2016-10-12

    Presymptomatic cortical thinning in familial Alzheimer disease: A longitudinal MRI study

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: The FAD cortical signature appears to be similar to that described for sporadic AD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2016-10-12

    Environmental risk factors for dementia: a systematic review

    ✓ Peer-reviewed Prevention and risk BMC geriatrics

    Key finding: Studies varied widely in size and quality and therefore we must be circumspect in our conclusions. +2 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2016-10-11

    Human whole genome genotype and transcriptome data for Alzheimer's and other neurodegenerative diseases

    ✓ Peer-reviewed Genetics Scientific data

    Key finding: Previous genome-wide association studies (GWAS), conducted by our group and others, have identified loci that harbor risk variants for neurodegenerative diseases, including Alzheimer's disease (AD). +4 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2016-10-11

    MRI uncovers disrupted hippocampal microstructure that underlies memory impairments after early-life adversity

    ✓ Peer-reviewed Hippocampus size on brain scans Hippocampus

    Key finding: Thus, disrupted hippocampal neuronal structure and connectivity, associated with cognitive impairments, are detectable via non-invasive imaging modalities in rats experiencing early-life adversity.

    Full summary, score breakdown and related studies → Original source

  24. 2016-10-11

    A systematic review of effectiveness of decision aids to assist older patients at the end of life

    ✓ Peer-reviewed End-of-life care Patient education and counseling

    Key finding: Continuing evaluation of DAs in routine practice to support advance care planning is worth exploring further.

    Full summary, score breakdown and related studies → Original source

  25. 2016-10-11

    Orthostatic Hypotension and the Long-Term Risk of Dementia: A Population-Based Study

    ✓ Peer-reviewed Long-term cohort studies PLoS medicine

    Key finding: Orthostatic hypotension (OH) is a common cause of transient cerebral hypoperfusion in the population. +3 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →