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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 11,701–11,725 of 27,380 studies, newest first · page 469 of 1096.

April 2020 25

  1. 2020-04-23

    TLR4 Cross-Talk With NLRP3 Inflammasome and Complement Signaling Pathways in Alzheimer's Disease

    ✓ Peer-reviewed Inflammation and the immune system Frontiers in immunology

    Key finding: Aβ fibrils and tau aggregates in the brain are closely associated with neuroinflammation and synapse loss, characterized by activated microglia and dystrophic neurites. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2020-04-23

    Incomplete penetrance in familial Alzheimer's disease with PSEN1 Ala260Gly mutation

    ✓ Peer-reviewed Risk genes beyond APOE Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

    Key finding: In order to evaluate whether or not epigenetic modifications could contribute to the phenotypic heterogeneity, we assessed global DNA methylation levels which resulted significantly higher in the three females than in their presymptomatic brother. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2020-04-23

    Self-reported health behaviors and longitudinal cognitive performance in late middle age: Results from the Wisconsin Registry for Alzheimer's Prevention

    ✓ Peer-reviewed Prevention trials PloS one

    Key finding: In this study, we explored whether several individual self-reported health behaviors were associated with cognitive decline when considered simultaneously, using data from the Wisconsin Registry for Alzheimer's Prevention (WRAP), an Alzheimer's disease risk-enriched cohort who were non-demented and in late midlife at baseline. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2020-04-23

    Modeling Parkinson's Disease With the Alpha-Synuclein Protein

    ✓ Peer-reviewed Lewy body dementia Frontiers in pharmacology

    Key finding: More precisely, the aggregation of α-Syn is associated with the dysfunctionality and degeneration of neurons in PD. +1 more finding

    Full summary, score breakdown and related studies → Original source

  5. 2020-04-22

    Protective effects of Akkermansia muciniphila on cognitive deficits and amyloid pathology in a mouse model of Alzheimer's disease

    ✓ Peer-reviewed Disease mechanisms Nutrition & diabetes

    Key finding: Akk effectively improved glucose tolerance, intestine barrier dysfunction and dyslipidemia in AD model mice. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2020-04-22

    Individual brain metabolic connectome indicator based on Kullback-Leibler Divergence Similarity Estimation predicts progression from mild cognitive impairment to Alzheimer's dementia

    ✓ Peer-reviewed Long-term cohort studies European journal of nuclear medicine and molecular imaging

    Key finding: Positron emission tomography (PET) with 18 F-fluorodeoxyglucose (FDG) reveals altered cerebral metabolism in individuals with mild cognitive impairment (MCI) and Alzheimer's dementia (AD). +3 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2020-04-22

    An update on blood-based biomarkers for non-Alzheimer neurodegenerative disorders

    ✓ Peer-reviewed Biomarkers Nature reviews. Neurology

    Key finding: Cerebrospinal fluid analyses and neuroimaging can identify the underlying pathophysiology at the earliest stage of some neurodegenerative disorders, but do not have the scalability needed for population screening. +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2020-04-21

    Identifying and Treating Insomnia in Patients Living With Alzheimer's Disease

    ✓ Peer-reviewed Risk factors The Journal of clinical psychiatry

    Key finding: The number of patients with Alzheimer's disease (AD) is increasing significantly.

    Full summary, score breakdown and related studies → Original source

  9. 2020-04-21

    [Toward a preventive management Alzheimer's disease]

    ✓ Peer-reviewed Prevention trials Bulletin de l'Academie nationale de medecine

    Key finding: However, three major data may change the severity of these pathologies: in young adults, simple measures of healthy lifestyle (control of vascular risk factors, physical activity and cognitive stimulation), have an impact on a future cognitive decline; the same lifestyle interventions may delay the start of the disease for elderly people potentially at-risk; finally, and for the first time, a monoclonal antibody directed against amyloid lesions has just shown a significant effect on the progression of AD in patients at an early stage of the disease. +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2020-04-21

    Early-phase [18F]PI-2620 tau-PET imaging as a surrogate marker of neuronal injury

    ✓ Peer-reviewed Brain scans and imaging European journal of nuclear medicine and molecular imaging

    Key finding: Highest agreement with [18F]FDG-PET quantification was reached for [18F]PI-2620-PET acquisition from 0.5 to 2.5 min p.i. for global mean (lowest R = 0.69) and cerebellar scaling (lowest R = 0.63). +4 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2020-04-21

    Sleep Disruption Exacerbates and Prolongs the Inflammatory Response to Traumatic Brain Injury

    ✓ Peer-reviewed TREM2 and immune genetics Journal of neurotrauma

    Key finding: Sleep disruption (SD) is an understudied post-injury environmental stressor that directly engages stress-immune pathways. +3 more findings

    Full summary, score breakdown and related studies → Original source

  12. 2020-04-21

    Human brain connectivity: Clinical applications for clinical neurophysiology

    ✓ Peer-reviewed Brain scans and imaging Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology

    Key finding: This manuscript is the second part of a two-part description of the current status of understanding of the network function of the brain in health and disease. +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2020-04-20

    Advance Care Planning for African American Caregivers of Relatives With Dementias: Cluster Randomized Controlled Trial

    ✓ Peer-reviewed End-of-life care The American journal of hospice & palliative care

    Key finding: Knowledge of CPR, MV, TF, and self-efficacy to make EOL treatment decisions increased significantly more in the ACT-Plan group at weeks 4 and 20. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2020-04-20

    Sex and gender differences in caregiving burden experienced by family caregivers of persons with dementia: A systematic review

    ✓ Peer-reviewed Caregiving PloS one

    Key finding: Current evidence on sex and gender differences in caregiving burden, mental and physical health is limited. +1 more finding

    Full summary, score breakdown and related studies → Original source

  15. 2020-04-19

    New Insights into the Molecular Bases of Familial Alzheimer's Disease

    ✓ Peer-reviewed Risk genes beyond APOE Journal of personalized medicine

    Key finding: Recent genetic studies have identified in four genes associated with inherited AD (amyloid precursor protein-APP, Presenilin-1, Presenilin-2 and Apolipoprotein E), rare mutations which cause dysregulation of APP processing and alterations of folding of the derived amyloid beta peptide (A).

    Full summary, score breakdown and related studies → Original source

  16. 2020-04-18

    Longitudinal flortaucipir ([18F]AV-1451) PET uptake in semantic dementia

    ✓ Peer-reviewed Brain scans and imaging Neurobiology of aging

    Key finding: Longitudinal analyses did not support significant changes in flortaucipir uptake between visits. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2020-04-18

    The impact of nutrition on COVID-19 susceptibility and long-term consequences

    ✓ Peer-reviewed Prevention and risk Brain, behavior, and immunity

    Key finding: The high rate of consumption of diets high in saturated fats, sugars, and refined carbohydrates (collectively called Western diet, WD) worldwide, contribute to the prevalence of obesity and type 2 diabetes, and could place these populations at an increased risk for severe COVID-19 pathology and mortality.

    Full summary, score breakdown and related studies → Original source

  18. 2020-04-18

    Findings of a Pilot Study Investigating the Effects of Mediterranean Diet and Aerobic Exercise on Cognition in Cognitively Healthy Older People Living Independently within Aged-Care Facilities: The Lifestyle Intervention in Independent Living Aged Care (LIILAC) Study

    ✓ Peer-reviewed Treatments Current developments in nutrition

    Key finding: This research indicates that diet and exercise programs have the potential to improve aspects of cognition and mood in an aging population. +3 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2020-04-17

    Association Between Family Caregiver Burden and Affiliate Stigma in the Families of People with Dementia

    ✓ Peer-reviewed Caregiving International journal of environmental research and public health

    Key finding: Affiliate stigma is the stigma internalized by individuals associated with PWD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2020-04-17

    Urban green space and the risks of dementia and stroke

    ✓ Peer-reviewed Digital health tools Environmental research

    Key finding: Increased exposure to urban green space was associated with reduced incidence of dementia and stroke. +2 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2020-04-17

    Proteomic and biological profiling of extracellular vesicles from Alzheimer's disease human brain tissues

    ✓ Peer-reviewed Digital health tools Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: In addition to Aβ and tau, ANXA5, VGF, GPM6A, and ACTZ are new signature proteins in AD EVs. +1 more finding

    Full summary, score breakdown and related studies → Original source

  22. 2020-04-17

    Predictors of attrition in a longitudinal population-based study of aging

    ✓ Peer-reviewed Digital health tools International psychogeriatrics

    Key finding: Attrition was most likely to occur in participants who were older, male, inactive, socially isolated, and cognitively impaired. +4 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2020-04-16

    Loneliness Increases the Risk of All-Cause Dementia and Alzheimer's Disease

    ✓ Peer-reviewed Risk factors The journals of gerontology. Series B, Psychological sciences and social sciences

    Key finding: During the follow-up, 428 developed dementia; 221 had AD, 157 had VaD, and 50 had dementia of other subtypes. +4 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2020-04-16

    Circadian and sleep dysfunction in Alzheimer's disease

    ✓ Peer-reviewed Inflammation and the immune system Ageing research reviews

    Key finding: Aging can alter both sleep timings and quality that can be strongly disrupted in AD. +4 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2020-04-15

    Co-occurrence of positive staff interactions and positive affect in memory-care residents: An observational study

    ✓ Peer-reviewed Health systems and care delivery International journal of geriatric psychiatry

    Key finding: The most observed resident affect type was neutral (53.1% of all minutes observed), followed by positive affect (44.5%). +4 more findings

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →