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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 15,451–15,475 of 27,380 studies, newest first · page 619 of 1096.

January 2017 25

  1. 2017 year only

    Comprehensive Screening for Disease Risk Variants in Early-Onset Alzheimer's Disease Genes in African Americans Identifies Novel PSEN Variants

    ✓ Peer-reviewed Risk genes beyond APOE Journal of Alzheimer's disease : JAD

    Key finding: We conducted a comprehensive screening of rare coding variants in an African American cohort to identify novel pathogenic mutations within the early-onset Alzheimer's disease (EOAD) genes (APP, PSEN1, and PSEN2) in this understudied population. +2 more findings

    Full summary, score breakdown and related studies → Original source

  2. 2017 year only

    TREM2 and the Progression of Alzheimer's Disease

    ✓ Peer-reviewed TREM2 and immune genetics Current neurovascular research

    Key finding: Interestingly, recent findings further suggested that the association between TREM2 variants and AD risk was quite diverse among different ethnicities and populations. +1 more finding

    Full summary, score breakdown and related studies → Original source

  3. 2017 year only

    No Genetic Overlap Between Circulating Iron Levels and Alzheimer's Disease

    ✓ Peer-reviewed Genetics Journal of Alzheimer's disease : JAD

    Key finding: Recently, peripheral iron measures have also been shown to be associated with AD status. +2 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2017 year only

    Apolipoprotein E-mediated Modulation of ADAM10 in Alzheimer's Disease

    ✓ Peer-reviewed Genetics Current Alzheimer research

    Key finding: In a cell free assay, ADAM10 activity was found to be significantly lower in apoE4 samples compared to apoE2. 7WCHO cells over expressing wild type AβPP exposed to apoE4 demonstrated reduced formation of sAβPPα compared to other apoE isoforms. +2 more findings

    Full summary, score breakdown and related studies → Original source

  5. 2017 year only

    Cerebrospinal Fluid Amyloid-β 42, Total Tau and Phosphorylated Tau are Low in Patients with Normal Pressure Hydrocephalus: Analogies and Differences with Alzheimer's Disease

    ✓ Peer-reviewed Tau biomarkers Journal of Alzheimer's disease : JAD

    Key finding: Aβ42 levels were significantly lower in NPH than in control patients, with no significant differences between AD and NPH. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2017 year only

    Plasma Tau Association with Brain Atrophy in Mild Cognitive Impairment and Alzheimer's Disease

    ✓ Peer-reviewed Tau biomarkers Journal of Alzheimer's disease : JAD

    Key finding: Plasma tau was negatively correlated with GMD in the medial temporal lobe (MTL), precuneus, thalamus, and striatum. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2017 year only

    Genetic Risk as a Marker of Amyloid-β and Tau Burden in Cerebrospinal Fluid

    ✓ Peer-reviewed Tau biomarkers Journal of Alzheimer's disease : JAD

    Key finding: In EDAR and DESCRIPA test data, inclusion of a case/control PGRS was no more predictive of Aβ, and a combined Aβ and tau endpoint than the basic models (accuracies of 66.0%, and 73.3% respectively). +4 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2017 year only

    Kidins220 Correlates with Tau in Alzheimer's Disease Brain and Cerebrospinal Fluid

    ✓ Peer-reviewed Tau biomarkers Journal of Alzheimer's disease : JAD

    Key finding: Identification of neurodegeneration-monitoring biomarkers would be of great clinical value for Alzheimer's disease (AD) diagnosis. +4 more findings

    Full summary, score breakdown and related studies → Original source

  9. 2017 year only

    Amyloid Imaging, Cerebrospinal Fluid Biomarkers Predict Driving Performance Among Cognitively Normal Individuals

    ✓ Peer-reviewed Tau biomarkers Alzheimer disease and associated disorders

    Key finding: Postmortem brain studies of older drivers killed in car accidents indicate that many had Alzheimer disease (AD) neuropathologic changes. +1 more finding

    Full summary, score breakdown and related studies → Original source

  10. 2017 year only

    Cerebral Amyloid Angiopathy-Related Microbleeds and Cerebrospinal Fluid Biomarkers in Alzheimer's Disease

    ✓ Peer-reviewed Tau biomarkers Journal of Alzheimer's disease : JAD

    Key finding: The 88 patients with AD included 15 with microbleeds only in cortical/subcortical regions (cortical microbleeds) that could be CAA-related, 16 with microbleeds only in deep locations (deep microbleeds), 3 with microbleeds in both cortical and deep locations (mixed microbleeds), and 54 without microbleeds. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2017 year only

    Plasma Amyloid-β and Alzheimer's Disease-Related Changes in Late-Life Depression

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: Higher plasma Aβ40, but not Aβ42 nor Aβ40/Aβ42 ratio, was associated with higher degree of parahippocampal atrophy and lower verbal fluency performance. +1 more finding

    Full summary, score breakdown and related studies → Original source

  12. 2017 year only

    Effect of Spinal Manometers on Cerebrospinal Fluid Amyloid-β Concentration

    ✓ Peer-reviewed Biomarkers Journal of Alzheimer's disease : JAD

    Key finding: Pooled human CSF samples were divided in two, one half passed through a manometer into a collection tube, the other transferred directly to a collection tube. +4 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2017-01-01

    Down Syndrome, Partial Trisomy 21, and Absence of Alzheimer's Disease: The Role of APP

    ✓ Peer-reviewed Down syndrome and Alzheimer's Journal of Alzheimer's disease : JAD

    Key finding: His serial neuropsychological test scores showed less than a 3% decline as compared to high functioning individuals with DS who developed dementia wherein the scores declined 17-28% per year. +1 more finding

    Full summary, score breakdown and related studies → Original source

  14. 2017-01-01

    Association Between Androgen Deprivation Therapy and Risk of Dementia

    ✓ Peer-reviewed Digital health tools JAMA oncology

    Key finding: Androgen deprivation therapy in the treatment of prostate cancer may be associated with an increased risk of dementia. +4 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2017-01-01

    The Mild Behavioral Impairment Checklist (MBI-C): A Rating Scale for Neuropsychiatric Symptoms in Pre-Dementia Populations

    ✓ Peer-reviewed Getting a diagnosis Journal of Alzheimer's disease : JAD

    Key finding: The MBI-C provides the first measure specifically developed to assess the MBI construct as explicitly described in the criteria.

    Full summary, score breakdown and related studies → Original source

  16. 2017-01-01

    Amyloid-Beta and Phosphorylated Tau Accumulations Cause Abnormalities at Synapses of Alzheimer's disease Neurons

    ✓ Peer-reviewed Disease mechanisms Journal of Alzheimer's disease : JAD

    Key finding: In vitro evidence suggests that Aβ and hyperphosphorylated tau have both direct and indirect cytotoxic effects that affect neurotransmission, axonal transport, signaling cascades, organelle function, and immune response in ways that lead to synaptic loss and dysfunctions in neurotransmitter release. +1 more finding

    Full summary, score breakdown and related studies → Original source

  17. 2017-01-01

    Oxidative Stress, Synaptic Dysfunction, and Alzheimer's Disease

    ✓ Peer-reviewed Disease mechanisms Journal of Alzheimer's disease : JAD

    Key finding: Increased production of reactive oxygen species (ROS) associated with age- and disease-dependent loss of mitochondrial function, altered metal homeostasis, and reduced antioxidant defense directly affect synaptic activity and neurotransmission in neurons leading to cognitive dysfunction. +1 more finding

    Full summary, score breakdown and related studies → Original source

  18. 2017-01-01

    Alzheimer's Disease Histological and Behavioral Manifestations in Transgenic Mice Correlate with Specific Gut Microbiome State

    ✓ Peer-reviewed Disease mechanisms Journal of Alzheimer's disease : JAD

    Key finding: First, the results indicated that impaired spatial learning and memory appeared in 6-month-old APP/PS1 mice and was further aggravated in the 8-month-old group, which was consistent with immunohistochemical studies of amyloid plaque. +1 more finding

    Full summary, score breakdown and related studies → Original source

  19. 2017-01-01

    Altered Gut Microbiome Composition and Tryptic Activity of the 5xFAD Alzheimer's Mouse Model

    ✓ Peer-reviewed Disease mechanisms Journal of Alzheimer's disease : JAD

    Key finding: By using a murine Alzheimer's disease model, we investigated a potential influence of disease-associated changes on gastrointestinal properties. 5xFAD mice at three different ages were compared to wild type littermates in regard to metabolic parameters and enzymes of the gut by fluorimetric enzyme assay and western blotting. +4 more findings

    Full summary, score breakdown and related studies → Original source

  20. 2017-01-01

    Altered Gut Microbiota in a Mouse Model of Alzheimer's Disease

    ✓ Peer-reviewed Disease mechanisms Journal of Alzheimer's disease : JAD

    Key finding: Our results showed that the microbiota composition and diversity were perturbed and the level of SCFAs was reduced in AD mice, predicting alterations in more than 30 metabolic pathways, which may be associated with amyloid deposition and ultrastructural abnormalities in AD mouse intestine. +1 more finding

    Full summary, score breakdown and related studies → Original source

  21. 2017-01-01

    Combustion-Derived Nanoparticles in Key Brain Target Cells and Organelles in Young Urbanites: Culprit Hidden in Plain Sight in Alzheimer's Disease Development

    ✓ Peer-reviewed Risk factors Journal of Alzheimer's disease : JAD

    Key finding: Millions of children and young adults are exposed to fine particulate matter (PM2.5) and ozone, associated with Alzheimer's disease (AD) risk. +4 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2017-01-01

    Sleep, Cognitive impairment, and Alzheimer's disease: A Systematic Review and Meta-Analysis

    ✓ Peer-reviewed Risk factors Sleep

    Key finding: Study objectives Mounting evidence implicates disturbed sleep or lack of sleep as one of the risk factors for Alzheimer's disease (AD), but the extent of the risk is uncertain. +3 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2017-01-01

    Effects of Regular and Long-Acting Insulin on Cognition and Alzheimer's Disease Biomarkers: A Pilot Clinical Trial

    ✓ Peer-reviewed Clinical trials Journal of Alzheimer's disease : JAD

    Key finding: Future research is warranted to examine the mechanistic basis of treatment differences, and to further assess the efficacy and safety of intranasal insulin. +3 more findings

    Full summary, score breakdown and related studies → Original source

  24. 2017-01-01

    Memantine for Alzheimer's Disease: An Updated Systematic Review and Meta-analysis

    ✓ Peer-reviewed Treatments Journal of Alzheimer's disease : JAD

    Key finding: The meta-analyses suggest the credible efficacy and safety of memantine in treating AD when used alone or in combination with ChEIs. +3 more findings

    Full summary, score breakdown and related studies → Original source

  25. 2017-01-01

    Role of Glutamate and NMDA Receptors in Alzheimer's Disease

    ✓ Peer-reviewed Treatments Journal of Alzheimer's disease : JAD

    Key finding: Studies indicate that the distinct outcomes of NMDAR-mediated responses are induced by regionalized receptor activities, followed by different downstream signaling pathways.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →