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Newest studies

Every summary in our library, newest first, as a dated timeline.

What "newest" means here

The most recent study in this library is dated 2026-11-01 (Paths of Aging Minds: Health Journeys of Older Adults with Mild Cognitive Impairment). This is our summary library, not a news wire — it is added to in batches, so the newest entry may not be the newest paper published anywhere.

Entries are sorted strictly by publication date, newest first. 26489 of the 27380 entries carry a full day-level date. 65 have no date recorded at all and are placed by publication year, at the start of that year; those are marked "no date recorded" below so you can see where the ordering is a best effort rather than a fact.

Prefer a reader? Subscribe to the Atom feed. Want them sorted by subject or by score instead? Browse the research library.

Showing 13,251–13,275 of 27,380 studies, newest first · page 531 of 1096.

January 2019 25

  1. 2019-01-09

    Association between serum cholesterol levels and Alzheimer's disease in China: a case-control study

    ✓ Peer-reviewed Risk factors International journal of food sciences and nutrition

    Key finding: Higher serum total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) levels and lower serum high-density lipoprotein cholesterol (HDL-C) levels associated with AD risk in the models adjusted for (1) age, sex and education; and (2) further adjusted for body mass index, smoking status, stroke, hypertension, type 2 diabetes mellitus and heart disease. +1 more finding

    Full summary, score breakdown and related studies → Original source

  2. 2019-01-09

    Gut microbiota in neurodegenerative disorders

    ✓ Peer-reviewed Disease mechanisms Journal of neuroimmunology

    Key finding: Studies revealed that intake of probiotics may help in the integrity of intestinal and BBB thus ameliorating the above neurodegenerative disorders.

    Full summary, score breakdown and related studies → Original source

  3. 2019-01-09

    A cellular complex of BACE1 and γ-secretase sequentially generates Aβ from its full-length precursor

    ✓ Peer-reviewed Biomarkers The Journal of cell biology

    Key finding: BACE1 coimmunoprecipitated and cofractionated with γ-secretase in cultured cells and in mouse and human brain. +4 more findings

    Full summary, score breakdown and related studies → Original source

  4. 2019-01-09

    The Active Ingredient of Cognitive Restoration: A Multicenter Randomized Controlled Trial of Sequential Combination of Aerobic Exercise and Computer-Based Cognitive Training in Stroke Survivors With Cognitive Decline

    ✓ Peer-reviewed Prevention trials Archives of physical medicine and rehabilitation

    Key finding: Aerobic exercise combined with computerized cognitive training has better effects on the cognitive functional status of survivors of stroke than an active control.

    Full summary, score breakdown and related studies → Original source

  5. 2019-01-09

    Associations between tau, Aβ, and cortical thickness with cognition in Alzheimer disease

    ✓ Peer-reviewed Brain scans and imaging Neurology

    Key finding: Our findings suggest that tau PET is more sensitive than Aβ PET and measures of cortical thickness for detecting early cognitive changes in preclinical AD. +1 more finding

    Full summary, score breakdown and related studies → Original source

  6. 2019-01-08

    Recent therapeutic strategies targeting beta amyloid and tauopathies in Alzheimer's disease

    ✓ Peer-reviewed Drug development Brain research bulletin

    Key finding: Approaches targeting cleavage and formation of toxic amyloid fragments by secretases, aggregation of amyloid monofilaments, and immunotherapy against amyloid deposits has been extensively studied to treat amyloid pathology. +4 more findings

    Full summary, score breakdown and related studies → Original source

  7. 2019-01-08

    Cognitive improvement effects of electro-acupuncture for the treatment of MCI compared with Western medications: a systematic review and Meta-analysis

    ✓ Peer-reviewed Digital health tools BMC complementary and alternative medicine

    Key finding: Electroacupuncture was an effective treatment for MCI patients by improving cognitive function. +3 more findings

    Full summary, score breakdown and related studies → Original source

  8. 2019-01-07

    Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer's models

    ✓ Peer-reviewed Tau biomarkers Nature medicine

    Key finding: Defective brain hormonal signaling has been associated with Alzheimer's disease (AD), a disorder characterized by synapse and memory failure. +1 more finding

    Full summary, score breakdown and related studies → Original source

  9. 2019-01-07

    Proinflammatory and anti-inflammatory cytokines in the CSF of patients with Alzheimer's disease and their correlation with cognitive decline

    ✓ Peer-reviewed Inflammation and the immune system Neurobiology of aging

    Key finding: The purpose of this work was to assess if patients with AD present a specific cerebrospinal fluid (CSF) cytokine profile and if it correlates to disease progression. +3 more findings

    Full summary, score breakdown and related studies → Original source

  10. 2019-01-07

    Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE

    ✓ Peer-reviewed TREM2 and immune genetics Nature neuroscience

    Key finding: We demonstrate that amyloid plaque seeding is increased in the absence of functional Trem2. +3 more findings

    Full summary, score breakdown and related studies → Original source

  11. 2019-01-07

    Cognitive and Pathological Influences of Tau Pathology in Lewy Body Disorders

    ✓ Peer-reviewed Digital health tools Annals of neurology

    Key finding: LBD patients with AD copathology harbor greater neocortical SYN pathology.

    Full summary, score breakdown and related studies → Original source

  12. 2019-01-07

    Vascular Risk and β-Amyloid Are Synergistically Associated with Cortical Tau

    ✓ Peer-reviewed Genetics Annals of neurology

    Key finding: These results suggest a potential link between vascular risk and tau pathology in preclinical AD. +3 more findings

    Full summary, score breakdown and related studies → Original source

  13. 2019-01-05

    Alcohol use and dementia: a systematic scoping review

    ✓ Peer-reviewed Prevention and risk Alzheimer's research & therapy

    Key finding: Reducing heavy alcohol use may be an effective dementia prevention strategy. +4 more findings

    Full summary, score breakdown and related studies → Original source

  14. 2019-01-04

    The Role of Nutrients in Reducing the Risk for Noncommunicable Diseases during Aging

    ✓ Peer-reviewed Costs and economics Nutrients

    Key finding: An increasing aging population worldwide accounts for a growing share of noncommunicable diseases (NCDs) of the overall social and economic burden. +3 more findings

    Full summary, score breakdown and related studies → Original source

  15. 2019-01-04

    Vision loss and 12-year risk of dementia in older adults: the 3C cohort study

    ✓ Peer-reviewed Risk factors European journal of epidemiology

    Key finding: In Cox multivariate analysis, moderate to severe near VI was associated with an increased risk of dementia in the first 2 years (HR 2.0, 95% CI 1.2-3.3) and from 2 to 4 years (HR 1.8, 95% CI 1.1-3.1) but the association was not significant beyond 4 years after inclusion even if pointing in similar direction (HR 1.3, 95% CI 0.95-1.9). +4 more findings

    Full summary, score breakdown and related studies → Original source

  16. 2019-01-04

    Plasma neuronal exosomes serve as biomarkers of cognitive impairment in HIV infection and Alzheimer's disease

    ✓ Peer-reviewed Biomarkers Journal of neurovirology

    Key finding: They belong to the spectrum of neurodegenerative diseases that result in death or dysfunction of neurons with similarities to Alzheimer disease (AD) but also distinctive differences (reviewed (Canet et al., Front Cell Neurosci 12: 307, 2018)). +2 more findings

    Full summary, score breakdown and related studies → Original source

  17. 2019-01-03

    Changes in Synaptic Proteins Precede Neurodegeneration Markers in Preclinical Alzheimer's Disease Cerebrospinal Fluid

    ✓ Peer-reviewed Genetics Molecular & Cellular Proteomics

    Key finding: In BriefIn the search for biomarkers of synapse loss associated with Alzheimer's disease (AD), we used shotgun proteomics to identify a panel of 9 synaptic proteins detectable in human cerebrospinal fluid (CSF).Expression at the human synapse was verified using super resolution microscopy.

    Full summary, score breakdown and related studies → Original source

  18. 2019-01-03

    A rare missense variant of CASP7 is associated with familial late-onset Alzheimer's disease

    ✓ Peer-reviewed Genetics Alzheimer's & dementia : the journal of the Alzheimer's Association

    Key finding: We identified associations in EAs with variants in 12 novel loci. +2 more findings

    Full summary, score breakdown and related studies → Original source

  19. 2019-01-03

    Nursing staff needs in providing palliative care for people with dementia at home or in long-term care facilities: A scoping review

    ✓ Peer-reviewed End-of-life care International journal of nursing studies

    Key finding: Of the 15 articles that were included, most used qualitative methods (N = 13) and were conducted in long-term care facilities (N = 14).

    Full summary, score breakdown and related studies → Original source

  20. 2019-01-02

    Astrocyte Biomarkers in Alzheimer's Disease

    ✓ Peer-reviewed Biomarkers Trends in molecular medicine

    Key finding: Astrocytes are integral to normal brain function and astrocyte reactivity is an early feature of AD, potentially providing a promising target for preclinical diagnosis and treatment. +4 more findings

    Full summary, score breakdown and related studies → Original source

  21. 2019-01-02

    Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk

    ✓ Peer-reviewed Risk genes beyond APOE Nature Genetics

    Key finding: Associated genes are strongly expressed in immune-related tissues and cell types (spleen, liver, and microglia). +2 more findings

    Full summary, score breakdown and related studies → Original source

  22. 2019-01-02

    Neuroinflammation in mild cognitive impairment and Alzheimer's disease: A meta-analysis

    ✓ Peer-reviewed Mild cognitive impairment Ageing research reviews

    Key finding: Our findings support the association of increased neuroinflammation during the progression of MCI and AD, relative to HCs. +3 more findings

    Full summary, score breakdown and related studies → Original source

  23. 2019-01-01

    Tau covariance patterns in Alzheimer's disease patients match intrinsic connectivity networks in the healthy brain

    ✓ Peer-reviewed Brain scans and imaging NeuroImage Clinical

    Key finding: We found a striking convergence between [ 18 F]flortaucipir covariance patterns and intrinsic connectivity maps (range Spearman rho's: 0.32–0.78, p < .001), which corresponded with expected functional networks (range goodness-of-fit: 3.8–8.2). +1 more finding

    Full summary, score breakdown and related studies → Original source

  24. 2019 year only

    Measuring Alzheimer's Disease and Other Dementias in Diverse Populations Using Medicare Claims Data

    ✓ Peer-reviewed Costs and economics Journal of Alzheimer's disease : JAD

    Key finding: We found levels differed by method from 3.1% annual incidence to 3.6% in 2014.

    Full summary, score breakdown and related studies → Original source

  25. 2019-01-01

    Who's Your Family?: African American Caregivers of Older Adults With Dementia

    ✓ Peer-reviewed Disparities Research in gerontological nursing

    Key finding: The nature and outcome of family caregiving is different for various racial and ethnic groups.

    Full summary, score breakdown and related studies → Original source

Browse the library by subject, with the full score breakdown →